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MX2020005143A - Uso de celulas t modificadas por receptor de antigeno quimerico para tratar cancer. - Google Patents

Uso de celulas t modificadas por receptor de antigeno quimerico para tratar cancer.

Info

Publication number
MX2020005143A
MX2020005143A MX2020005143A MX2020005143A MX2020005143A MX 2020005143 A MX2020005143 A MX 2020005143A MX 2020005143 A MX2020005143 A MX 2020005143A MX 2020005143 A MX2020005143 A MX 2020005143A MX 2020005143 A MX2020005143 A MX 2020005143A
Authority
MX
Mexico
Prior art keywords
modified
cells
antigen receptor
chimeric antigen
treat cancer
Prior art date
Application number
MX2020005143A
Other languages
English (en)
Inventor
Carl H June
Bruce L Levine
Michael D Kalos
David L Porter
Michael C Milone
Original Assignee
Univ Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46207528&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2020005143(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Pennsylvania filed Critical Univ Pennsylvania
Publication of MX2020005143A publication Critical patent/MX2020005143A/es

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Abstract

La presente invención provee composiciones y métodos para tratar cáncer en un humano; la invención se refiere a la administración de una célula T genéticamente modificada para expresar un CAR en donde el CAR comprende un dominio de unión a antígeno, un dominio de transmembrana, una región de señalización co-estimulante, y un dominio de señalización de CD3 zeta.
MX2020005143A 2010-12-09 2013-06-07 Uso de celulas t modificadas por receptor de antigeno quimerico para tratar cancer. MX2020005143A (es)

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