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BR9810920A - Modificação da forma de cristal de um derivado de n-fenil-2-pirimidinoamina, processos para sua fabricação e seu uso - Google Patents

Modificação da forma de cristal de um derivado de n-fenil-2-pirimidinoamina, processos para sua fabricação e seu uso

Info

Publication number
BR9810920A
BR9810920A BR9810920-0A BR9810920A BR9810920A BR 9810920 A BR9810920 A BR 9810920A BR 9810920 A BR9810920 A BR 9810920A BR 9810920 A BR9810920 A BR 9810920A
Authority
BR
Brazil
Prior art keywords
phenyl
pyrimidinoamine
derivative
modification
manufacture
Prior art date
Application number
BR9810920-0A
Other languages
English (en)
Inventor
Juerg Zimmermann
Bertrand Sutter
Hans Michael Buerger
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4218028&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9810920(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BR9810920A publication Critical patent/BR9810920A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C30—CRYSTAL GROWTH
    • C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
    • C30B7/00—Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Metallurgy (AREA)
  • Materials Engineering (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)

Abstract

Patente de Invenção: <B>"MODIFICAçãO DA FORMA DE CRISTAL DE UM DERIVADO DE N-FENIL-2-PIRIMIDINOAMINA, PROCESSOS PARA SUA FABRICAçãO E SEU USO"<D>. A presente invenção refere-se a uma nova forma cristalina do sal de adição de ácido metanossulfónico de 4-(4-metilpiperazin-1-ilmetil)-N-[4-metil-3-(4-piridin-3-il)pirimidin-2-ilamin o)fenil]-benzamida de fórmula 1, que pode ser usada, por exemplo, na terapia de tumor.
BR9810920-0A 1997-07-18 1998-07-16 Modificação da forma de cristal de um derivado de n-fenil-2-pirimidinoamina, processos para sua fabricação e seu uso BR9810920A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH176497 1997-07-18
PCT/EP1998/004427 WO1999003854A1 (en) 1997-07-18 1998-07-16 Crystal modification of a n-phenyl-2-pyrimidineamine derivative, processes for its manufacture and its use

Publications (1)

Publication Number Publication Date
BR9810920A true BR9810920A (pt) 2000-08-15

Family

ID=4218028

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9810920-0A BR9810920A (pt) 1997-07-18 1998-07-16 Modificação da forma de cristal de um derivado de n-fenil-2-pirimidinoamina, processos para sua fabricação e seu uso

Country Status (30)

Country Link
US (5) US6894051B1 (pt)
EP (1) EP0998473B1 (pt)
JP (1) JP3276359B2 (pt)
KR (1) KR100450356B1 (pt)
CN (1) CN1134430C (pt)
AR (2) AR016351A1 (pt)
AT (1) ATE251152T1 (pt)
AU (1) AU740713B2 (pt)
BR (1) BR9810920A (pt)
CA (1) CA2296604C (pt)
CO (1) CO4940418A1 (pt)
CZ (1) CZ298531B6 (pt)
DE (1) DE69818674T2 (pt)
DK (1) DK0998473T3 (pt)
ES (1) ES2209194T3 (pt)
HU (1) HU230185B1 (pt)
ID (1) ID24093A (pt)
IL (5) IL133906A0 (pt)
MY (2) MY129772A (pt)
NO (2) NO319486B1 (pt)
NZ (1) NZ502295A (pt)
PE (1) PE97899A1 (pt)
PL (1) PL188348B1 (pt)
PT (1) PT998473E (pt)
RU (1) RU2208012C2 (pt)
SK (2) SK287276B6 (pt)
TR (1) TR200000060T2 (pt)
TW (1) TW491845B (pt)
WO (1) WO1999003854A1 (pt)
ZA (1) ZA986362B (pt)

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