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BG63121B1 - Таксоиди, тяхното получаване и фармацевтични състави, които ги съдържат - Google Patents

Таксоиди, тяхното получаване и фармацевтични състави, които ги съдържат Download PDF

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Publication number
BG63121B1
BG63121B1 BG101918A BG10191897A BG63121B1 BG 63121 B1 BG63121 B1 BG 63121B1 BG 101918 A BG101918 A BG 101918A BG 10191897 A BG10191897 A BG 10191897A BG 63121 B1 BG63121 B1 BG 63121B1
Authority
BG
Bulgaria
Prior art keywords
radical
oddc
carbon atoms
cancer
general formula
Prior art date
Application number
BG101918A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG101918A (en
Inventor
Herve Bouchard
Jean-Dominique Bourzat
Alain Commercon
Original Assignee
Rhone-Poulenc Rorer S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9503545A external-priority patent/FR2732340B1/fr
Priority claimed from FR9515381A external-priority patent/FR2742754B1/fr
Application filed by Rhone-Poulenc Rorer S.A. filed Critical Rhone-Poulenc Rorer S.A.
Publication of BG101918A publication Critical patent/BG101918A/xx
Publication of BG63121B1 publication Critical patent/BG63121B1/bg

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BG101918A 1995-03-27 1997-09-25 Таксоиди, тяхното получаване и фармацевтични състави, които ги съдържат BG63121B1 (bg)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9503545A FR2732340B1 (fr) 1995-03-27 1995-03-27 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
FR9515381A FR2742754B1 (fr) 1995-12-22 1995-12-22 Procede de preparation de taxoides
PCT/FR1996/000441 WO1996030356A1 (fr) 1995-03-27 1996-03-25 Nouveaux taxoïdes, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
BG101918A BG101918A (en) 1998-10-30
BG63121B1 true BG63121B1 (bg) 2001-04-30

Family

ID=26231838

Family Applications (2)

Application Number Title Priority Date Filing Date
BG101918A BG63121B1 (bg) 1995-03-27 1997-09-25 Таксоиди, тяхното получаване и фармацевтични състави, които ги съдържат
BG101917A BG63009B1 (bg) 1995-03-27 1997-09-25 Таксоиди,тяхното получаване и фармацевтични състави, които ги съдържат

Family Applications After (1)

Application Number Title Priority Date Filing Date
BG101917A BG63009B1 (bg) 1995-03-27 1997-09-25 Таксоиди,тяхното получаване и фармацевтични състави, които ги съдържат

Country Status (41)

Country Link
US (3) US5889043A (cs)
EP (2) EP0817780B1 (cs)
JP (2) JP3790826B2 (cs)
KR (2) KR100485309B1 (cs)
CN (2) CN1213042C (cs)
AP (2) AP785A (cs)
AR (1) AR001440A1 (cs)
AT (2) ATE188471T1 (cs)
AU (2) AU703278B2 (cs)
BG (2) BG63121B1 (cs)
BR (2) BR9607929A (cs)
CA (2) CA2214321C (cs)
CO (1) CO4700576A1 (cs)
CZ (2) CZ287326B6 (cs)
DE (2) DE69604653T2 (cs)
DK (2) DK0817780T3 (cs)
DZ (1) DZ2009A1 (cs)
EA (2) EA000567B1 (cs)
EE (2) EE03608B1 (cs)
ES (2) ES2140075T3 (cs)
GE (2) GEP20002188B (cs)
GR (2) GR3031526T3 (cs)
HU (2) HU223666B1 (cs)
IL (1) IL117636A (cs)
IS (2) IS2058B (cs)
MA (1) MA23823A1 (cs)
MY (1) MY121225A (cs)
NO (2) NO316607B1 (cs)
NZ (2) NZ304900A (cs)
OA (2) OA10513A (cs)
PE (1) PE51097A1 (cs)
PL (2) PL188284B1 (cs)
PT (1) PT817779E (cs)
RO (2) RO115878B1 (cs)
SK (2) SK281927B6 (cs)
TN (1) TNSN96043A1 (cs)
TR (2) TR199701042T1 (cs)
TW (1) TW394765B (cs)
UY (2) UY24192A1 (cs)
WO (2) WO1996030355A1 (cs)
ZA (1) ZA962399B (cs)

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US6593334B1 (en) 2002-05-02 2003-07-15 The University Of North Carolina At Chapel Hill Camptothecin-taxoid conjugates as antimitotic and antitumor agents
KR101268258B1 (ko) 2002-09-06 2013-05-31 인설트 테라페틱스, 인코퍼레이티드 공유결합된 치료제 전달을 위한 사이클로덱스트린-기초 중합체
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CN102408397B (zh) 2011-10-19 2014-08-20 上海贝美医药科技有限公司 紫杉烷类衍生物及其制备方法
CN102424672A (zh) * 2011-10-20 2012-04-25 江苏红豆杉生物科技有限公司 脱保护基制备二甲氧基紫杉烷类化合物的方法
CN102516281B (zh) * 2011-10-20 2015-02-04 江苏红豆杉生物科技股份有限公司 一种10-脱乙酰基巴卡丁iii及其衍生物甲氧基化的方法
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PL3258931T3 (pl) 2015-02-17 2020-12-28 Erasmus University Medical Center Rotterdam Zastosowanie kabazitakselu w leczeniu nowotworu złośliwego prostaty
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Also Published As

Publication number Publication date
ZA962399B (en) 1996-10-01
JPH11500141A (ja) 1999-01-06
SK130297A3 (en) 1998-03-04
US6331635B1 (en) 2001-12-18
HUP9801201A3 (en) 2000-12-28
CN1179775A (zh) 1998-04-22
EE03608B1 (et) 2002-02-15
ATE185562T1 (de) 1999-10-15
PL188284B1 (pl) 2005-01-31
NO973922L (no) 1997-08-26
WO1996030355A1 (fr) 1996-10-03
BR9607929A (pt) 1998-06-02
DE69604653T2 (de) 2000-05-31
PT817779E (pt) 2000-04-28
CZ303297A3 (cs) 1998-01-14
GEP20002211B (en) 2000-08-25
CZ287468B6 (en) 2000-12-13
DZ2009A1 (fr) 2002-10-23
IL117636A (en) 2004-08-31
RO115878B1 (ro) 2000-07-28
CA2214321A1 (fr) 1996-10-03
AP9701090A0 (en) 1997-10-31
AP753A (en) 1999-07-21
OA10514A (fr) 2002-04-22
EP0817780A1 (fr) 1998-01-14
EE03609B1 (et) 2002-02-15
EE9700323A (et) 1998-06-15
AR001440A1 (es) 1997-10-22
EE9700315A (et) 1998-06-15
IS2058B (is) 2005-10-14
ES2140075T3 (es) 2000-02-16
HU223666B1 (hu) 2004-11-29
SK281928B6 (sk) 2001-09-11
NO973923L (no) 1997-08-26
AU711227B2 (en) 1999-10-07
ATE188471T1 (de) 2000-01-15
WO1996030356A1 (fr) 1996-10-03
SK281927B6 (sk) 2001-09-11
HUP9801204A3 (en) 2000-12-28
EA199700269A1 (ru) 1998-04-30
NO973922D0 (no) 1997-08-26
IS2056B (is) 2005-10-14
BG101918A (en) 1998-10-30
HUP9801204A1 (hu) 2000-05-28
KR100485309B1 (ko) 2005-10-12
US20020038038A1 (en) 2002-03-28
RO115877B1 (ro) 2000-07-28
NO973923D0 (no) 1997-08-26
BG101917A (en) 1998-10-30
IL117636A0 (en) 1996-07-23
CN1152870C (zh) 2004-06-09
TW394765B (en) 2000-06-21
NO316379B1 (no) 2004-01-19
JP2941951B2 (ja) 1999-08-30
DE69604653D1 (de) 1999-11-18
JPH11502531A (ja) 1999-03-02
EA000567B1 (ru) 1999-12-29
DK0817780T3 (da) 2000-03-27
CA2214319C (fr) 2004-02-17
CA2214319A1 (fr) 1996-10-03
PE51097A1 (es) 1997-12-22
OA10513A (fr) 2002-04-22
PL322465A1 (en) 1998-02-02
KR100297196B1 (ko) 2001-11-22
JP3790826B2 (ja) 2006-06-28
MX9706278A (es) 1997-10-31
EA199700270A1 (ru) 1998-02-26
IS4567A (is) 1997-09-23
EP0817779B1 (fr) 2000-01-05
EP0817779A1 (fr) 1998-01-14
CN1213042C (zh) 2005-08-03
MA23823A1 (fr) 1996-10-01
DE69606028T2 (de) 2000-08-10
KR19980703287A (ko) 1998-10-15
HU223732B1 (hu) 2004-12-28
PL188987B1 (pl) 2005-05-31
HUP9801201A2 (hu) 2000-05-28
AP9701093A0 (en) 1997-10-31
UY24370A1 (es) 2001-10-25
AU5278096A (en) 1996-10-16
AU703278B2 (en) 1999-03-25
CZ287326B6 (en) 2000-10-11
NO316607B1 (no) 2004-03-08
TR199701040T1 (xx) 1998-01-21
IS4536A (is) 1997-07-31
DK0817779T3 (da) 2000-06-19
CO4700576A1 (es) 1998-12-29
GEP20002188B (en) 2000-07-25
EA000709B1 (ru) 2000-02-28
UY24192A1 (es) 1996-06-14
BR9607930A (pt) 1998-06-02
NZ304900A (en) 1998-09-24
MY121225A (en) 2006-01-28
TNSN96043A1 (fr) 2005-03-15
MX9706568A (es) 1997-11-29
AU5278196A (en) 1996-10-16
KR19980703357A (ko) 1998-10-15
TR199701042T1 (xx) 1998-01-21
GR3031526T3 (en) 2000-01-31
SK130197A3 (en) 1998-04-08
EP0817780B1 (fr) 1999-10-13
DE69606028D1 (de) 2000-02-10
PL322499A1 (en) 1998-02-02
NZ304901A (en) 1998-12-23
ES2143187T3 (es) 2000-05-01
GR3032316T3 (en) 2000-04-27
US5889043A (en) 1999-03-30
CZ303097A3 (cs) 1998-01-14
BG63009B1 (bg) 2001-01-31
CN1179776A (zh) 1998-04-22
CA2214321C (fr) 2008-01-22
US6387946B1 (en) 2002-05-14
AP785A (en) 1999-11-26

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