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MX2021012478A - Formas cristalinas de un inhibidor de tirosina quinasa de bruton. - Google Patents

Formas cristalinas de un inhibidor de tirosina quinasa de bruton.

Info

Publication number
MX2021012478A
MX2021012478A MX2021012478A MX2021012478A MX2021012478A MX 2021012478 A MX2021012478 A MX 2021012478A MX 2021012478 A MX2021012478 A MX 2021012478A MX 2021012478 A MX2021012478 A MX 2021012478A MX 2021012478 A MX2021012478 A MX 2021012478A
Authority
MX
Mexico
Prior art keywords
bruton
tyrosine kinase
inhibitor
kinase inhibitor
conditions
Prior art date
Application number
MX2021012478A
Other languages
English (en)
Inventor
Mark Smyth
Erick Goldman
David D Wirth
Norbert Purro
Original Assignee
Pharmacyclics Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49712527&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2021012478(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacyclics Llc filed Critical Pharmacyclics Llc
Publication of MX2021012478A publication Critical patent/MX2021012478A/es

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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Abstract

Se describe aquí al inhibidor de tirosina quinasa (Btk) de Bruton 1-((R)-3-(4-amino-3-(4-fenoxifenil)-1H-pirazolo[3,4-d] pirimidin-1-il)piperidin-1-il)prop-2-en-1-ona, incluyendo las formas cristalinas, solvatos y sus sales aceptables en el campo farmacéutico. Se describen también composiciones farmacéuticas que incluyen al inhibidor Btk, así como composiciones para usar a dicho inhibidor solo o en combinación con otros agentes terapéuticos, en el tratamiento de enfermedades o condiciones autoinmunes, enfermedades o condiciones heteroinmunes, cáncer, incluyendo linfoma, así como enfermedades o condiciones inflamatorias.
MX2021012478A 2012-06-04 2014-12-04 Formas cristalinas de un inhibidor de tirosina quinasa de bruton. MX2021012478A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261655381P 2012-06-04 2012-06-04

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MX2021012478A true MX2021012478A (es) 2021-11-12

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MX2017006815A MX387669B (es) 2012-06-04 2013-06-03 Formas cristalinas de un inhibidor de tirosina quinasa de bruton.
MX2014014848A MX348290B (es) 2012-06-04 2013-06-03 Formas cristalinas de un inhibidor de tirosina quinasa de bruton.
MX2021012478A MX2021012478A (es) 2012-06-04 2014-12-04 Formas cristalinas de un inhibidor de tirosina quinasa de bruton.

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MX2017006815A MX387669B (es) 2012-06-04 2013-06-03 Formas cristalinas de un inhibidor de tirosina quinasa de bruton.
MX2014014848A MX348290B (es) 2012-06-04 2013-06-03 Formas cristalinas de un inhibidor de tirosina quinasa de bruton.

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US (26) US9296753B2 (es)
EP (1) EP2854859A4 (es)
JP (10) JP6236071B2 (es)
KR (8) KR20170091785A (es)
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EP2526934B1 (en) * 2006-09-22 2015-12-09 Pharmacyclics LLC Inhibitors of bruton's tyrosine kinase
US20120101113A1 (en) 2007-03-28 2012-04-26 Pharmacyclics, Inc. Inhibitors of bruton's tyrosine kinase
ES2660418T3 (es) 2008-07-16 2018-03-22 Pharmacyclics Llc Inhibidores de la tirosina quinasa de Bruton para el tratamiento de tumores sólidos
US8491927B2 (en) * 2009-12-02 2013-07-23 Nimble Epitech, Llc Pharmaceutical composition containing a hypomethylating agent and a histone deacetylase inhibitor
CA3240281A1 (en) 2010-06-03 2011-12-08 Pharmacyclics Llc Use of inhibitors of bruton's tyrosine kinase (btk) in the treatment of follicular lymphoma
AU2012205601B2 (en) 2011-01-11 2016-03-24 Novartis Ag Combination
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