MX2018008772A - Formulaciones/composiciones que comprenden un inhibidor de btk. - Google Patents
Formulaciones/composiciones que comprenden un inhibidor de btk.Info
- Publication number
- MX2018008772A MX2018008772A MX2018008772A MX2018008772A MX2018008772A MX 2018008772 A MX2018008772 A MX 2018008772A MX 2018008772 A MX2018008772 A MX 2018008772A MX 2018008772 A MX2018008772 A MX 2018008772A MX 2018008772 A MX2018008772 A MX 2018008772A
- Authority
- MX
- Mexico
- Prior art keywords
- formulations
- compositions
- btk inhibitor
- ibrutinib
- disease
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 8
- 238000009472 formulation Methods 0.000 title abstract 4
- 229940124291 BTK inhibitor Drugs 0.000 title abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000002177 L01XE27 - Ibrutinib Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229960001507 ibrutinib Drugs 0.000 abstract 1
- XYFPWWZEPKGCCK-GOSISDBHSA-N ibrutinib Chemical compound C1=2C(N)=NC=NC=2N([C@H]2CN(CCC2)C(=O)C=C)N=C1C(C=C1)=CC=C1OC1=CC=CC=C1 XYFPWWZEPKGCCK-GOSISDBHSA-N 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Inorganic Chemistry (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Se divulgan formulaciones/composiciones que comprenden un inhibidor de BTK, especialmente ibrutinib: (ver formula) asi como los procesos para preparar dichas formulaciones/composiciones y metodos para el tratamiento de una enfermedad o dolencia que comprende el uso de dichas formulaciones/composiciones.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN201621001987 | 2016-01-19 | ||
| PCT/EP2017/050964 WO2017125424A1 (en) | 2016-01-19 | 2017-01-18 | Formulations/compositions comprising a btk inhibitor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2018008772A true MX2018008772A (es) | 2018-11-09 |
Family
ID=57851068
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018008772A MX2018008772A (es) | 2016-01-19 | 2017-01-18 | Formulaciones/composiciones que comprenden un inhibidor de btk. |
| MX2022006817A MX2022006817A (es) | 2016-01-19 | 2018-07-17 | Formulaciones/composiciones que comprenden un inhibidor de btk. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2022006817A MX2022006817A (es) | 2016-01-19 | 2018-07-17 | Formulaciones/composiciones que comprenden un inhibidor de btk. |
Country Status (25)
| Country | Link |
|---|---|
| US (3) | US20190290650A1 (es) |
| EP (2) | EP3405178B1 (es) |
| JP (3) | JP7336195B2 (es) |
| KR (2) | KR20180102150A (es) |
| CN (2) | CN108472258B (es) |
| AR (1) | AR107392A1 (es) |
| AU (1) | AU2017208473B2 (es) |
| BR (1) | BR112018014540B1 (es) |
| CA (1) | CA3008576A1 (es) |
| DK (1) | DK3405178T3 (es) |
| EA (1) | EA201891664A1 (es) |
| ES (1) | ES3041841T3 (es) |
| FI (1) | FI3405178T3 (es) |
| HK (2) | HK1259433A1 (es) |
| HR (1) | HRP20251152T1 (es) |
| LT (1) | LT3405178T (es) |
| MA (1) | MA43650B1 (es) |
| MX (2) | MX2018008772A (es) |
| PL (1) | PL3405178T3 (es) |
| PT (1) | PT3405178T (es) |
| RS (1) | RS67236B1 (es) |
| SI (1) | SI3405178T1 (es) |
| SM (1) | SMT202500360T1 (es) |
| TW (1) | TWI794153B (es) |
| WO (1) | WO2017125424A1 (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX387669B (es) | 2012-06-04 | 2025-03-18 | Pharmacyclics Llc | Formas cristalinas de un inhibidor de tirosina quinasa de bruton. |
| IL315294A (en) | 2015-03-03 | 2024-10-01 | Pharmacyclics Llc | Pharmaceutical formulations of bruton's tyrosine kinase inhibitor |
| US20190290650A1 (en) * | 2016-01-19 | 2019-09-26 | Janssen Pharmaceutic Nv | Formulations/compositions comprising a btk inhibitor |
| JP7590810B2 (ja) | 2016-10-06 | 2024-11-27 | ヤンセン ファーマシューティカ エヌ．ベー． | Ｂｔｋ阻害剤を調製するための方法および中間体 |
| EP3824906A1 (en) | 2016-12-21 | 2021-05-26 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| US11576917B2 (en) | 2018-01-20 | 2023-02-14 | Natco Pharma Limited | Pharmaceutical compositions comprising Ibrutinib |
| EP3575300A1 (en) | 2018-05-31 | 2019-12-04 | Apotex Inc. | Novel crystalline forms of ibrutinib |
| MA52874A (fr) | 2018-06-15 | 2021-04-21 | Janssen Pharmaceutica Nv | Formulations/compositions comprenant de l'ibrutinib |
| US10688050B1 (en) * | 2018-12-21 | 2020-06-23 | Synthon B.V. | Pharmaceutical composition comprising ibrutinib |
| BR112022007468A2 (pt) * | 2019-10-21 | 2022-07-12 | Celgene Corp | Composições farmacêuticas compreendendo (s)-2-(2,6-dioxopiperidin-3-il)-4-((2-fluoro-4-((3-morfolinoazetidin-1-il)metil)benzil)amino)isoindolina-1,3-diona e métodos para usar as mesmas |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4327725A (en) | 1980-11-25 | 1982-05-04 | Alza Corporation | Osmotic device with hydrogel driving member |
| US4624848A (en) | 1984-05-10 | 1986-11-25 | Ciba-Geigy Corporation | Active agent containing hydrogel devices wherein the active agent concentration profile contains a sigmoidal concentration gradient for improved constant release, their manufacture and use |
| US4968509A (en) | 1987-07-27 | 1990-11-06 | Mcneilab, Inc. | Oral sustained release acetaminophen formulation and process |
| IL92966A (en) | 1989-01-12 | 1995-07-31 | Pfizer | Dispensing devices powered by hydrogel |
| JP2527107B2 (ja) | 1991-04-16 | 1996-08-21 | 日本新薬株式会社 | 固体分散体の製造方法 |
| CZ282760B6 (cs) | 1991-11-22 | 1997-09-17 | Procter And Gamble Pharmaceuticals, Inc. | Risedronátové prostředky se zpožděným uvolňováním |
| US5461140A (en) | 1992-04-30 | 1995-10-24 | Pharmaceutical Delivery Systems | Bioerodible polymers for solid controlled release pharmaceutical compositions |
| US5323907A (en) | 1992-06-23 | 1994-06-28 | Multi-Comp, Inc. | Child resistant package assembly for dispensing pharmaceutical medications |
| CA2147283C (en) | 1992-10-16 | 2007-01-16 | Kouichi Nakamichi | Method of manufacturing wax matrices |
| US5686105A (en) | 1993-10-19 | 1997-11-11 | The Procter & Gamble Company | Pharmaceutical dosage form with multiple enteric polymer coatings for colonic delivery |
| US6326469B1 (en) | 1994-04-22 | 2001-12-04 | Sugen, Inc. | Megakaryocytic protein tyrosine kinases |
| JPH11505258A (ja) | 1995-05-17 | 1999-05-18 | セダーシナイ メディカル センター | 小腸における消化および吸収を改善させる脂肪酸を含む組成物 |
| US6395300B1 (en) | 1999-05-27 | 2002-05-28 | Acusphere, Inc. | Porous drug matrices and methods of manufacture thereof |
| US6465014B1 (en) | 2001-03-21 | 2002-10-15 | Isp Investments Inc. | pH-dependent sustained release, drug-delivery composition |
| CA2537254A1 (en) | 2003-09-03 | 2005-03-17 | Government Of The United States Of America, As Represented By Secretary, Department Of Health And Human Services | Methods for identifying, diagnosing, and predicting survival of lymphomas |
| PL2529621T3 (pl) | 2006-09-22 | 2017-06-30 | Pharmacyclics Llc | Inhibitory kinazy tyrozynowej brutona |
| KR20230109775A (ko) * | 2011-10-19 | 2023-07-20 | 파마싸이클릭스 엘엘씨 | 브루톤 티로신 인산화효소(btk)의 억제제의 용도 |
| MX387669B (es) * | 2012-06-04 | 2025-03-18 | Pharmacyclics Llc | Formas cristalinas de un inhibidor de tirosina quinasa de bruton. |
| WO2014004707A1 (en) * | 2012-06-29 | 2014-01-03 | Principia Biopharma Inc. | Formulations comprising ibrutinib |
| HK1224173A1 (zh) * | 2013-03-14 | 2017-08-18 | Pharmacyclics Llc | 布鲁顿氏酪氨酸激酶抑制剂和cyp3a4抑制剂的组合 |
| WO2015071432A1 (en) * | 2013-11-14 | 2015-05-21 | Sandoz Ag | Pharmaceutical compositions of ibrutinib |
| CN104523695A (zh) * | 2014-11-12 | 2015-04-22 | 广东东阳光药业有限公司 | 一种治疗过度增生性疾病的药物组合物 |
| US20190290650A1 (en) * | 2016-01-19 | 2019-09-26 | Janssen Pharmaceutic Nv | Formulations/compositions comprising a btk inhibitor |
| EP3405177A1 (en) * | 2016-01-19 | 2018-11-28 | Janssen Pharmaceutica NV | Formulations/compositions comprising a btk inhibitor |
-
2017
- 2017-01-18 US US16/071,453 patent/US20190290650A1/en not_active Abandoned
- 2017-01-18 MA MA43650A patent/MA43650B1/fr unknown
- 2017-01-18 KR KR1020187023229A patent/KR20180102150A/ko active Pending
- 2017-01-18 CA CA3008576A patent/CA3008576A1/en active Pending
- 2017-01-18 RS RS20250946A patent/RS67236B1/sr unknown
- 2017-01-18 SI SI201731626T patent/SI3405178T1/sl unknown
- 2017-01-18 DK DK17700821.6T patent/DK3405178T3/da active
- 2017-01-18 JP JP2018556012A patent/JP7336195B2/ja active Active
- 2017-01-18 WO PCT/EP2017/050964 patent/WO2017125424A1/en not_active Ceased
- 2017-01-18 HR HRP20251152TT patent/HRP20251152T1/hr unknown
- 2017-01-18 EA EA201891664A patent/EA201891664A1/ru unknown
- 2017-01-18 HK HK19101837.4A patent/HK1259433A1/zh unknown
- 2017-01-18 EP EP17700821.6A patent/EP3405178B1/en active Active
- 2017-01-18 MX MX2018008772A patent/MX2018008772A/es unknown
- 2017-01-18 LT LTEPPCT/EP2017/050964T patent/LT3405178T/lt unknown
- 2017-01-18 AU AU2017208473A patent/AU2017208473B2/en active Active
- 2017-01-18 HK HK19101845.4A patent/HK1259441A1/zh unknown
- 2017-01-18 PL PL17700821.6T patent/PL3405178T3/pl unknown
- 2017-01-18 ES ES17700821T patent/ES3041841T3/es active Active
- 2017-01-18 SM SM20250360T patent/SMT202500360T1/it unknown
- 2017-01-18 CN CN201780006739.5A patent/CN108472258B/zh active Active
- 2017-01-18 FI FIEP17700821.6T patent/FI3405178T3/fi active
- 2017-01-18 BR BR112018014540-8A patent/BR112018014540B1/pt active IP Right Grant
- 2017-01-18 EP EP25183977.5A patent/EP4663247A2/en active Pending
- 2017-01-18 CN CN202210154359.9A patent/CN114681462A/zh active Pending
- 2017-01-18 KR KR1020257004789A patent/KR20250025518A/ko active Pending
- 2017-01-18 PT PT177008216T patent/PT3405178T/pt unknown
- 2017-01-19 AR ARP170100142A patent/AR107392A1/es unknown
- 2017-01-19 TW TW106101787A patent/TWI794153B/zh not_active IP Right Cessation
-
2018
- 2018-07-17 MX MX2022006817A patent/MX2022006817A/es unknown
-
2021
- 2021-02-11 US US17/174,305 patent/US20210169888A1/en not_active Abandoned
-
2022
- 2022-04-07 JP JP2022063752A patent/JP7565971B2/ja active Active
- 2022-11-22 US US17/992,348 patent/US20230364090A1/en not_active Abandoned
-
2024
- 2024-06-05 JP JP2024091441A patent/JP2024138243A/ja active Pending
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