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FI970800A0 - Migreeninvastaisia indolijohdossuoloja - Google Patents

Migreeninvastaisia indolijohdossuoloja

Info

Publication number
FI970800A0
FI970800A0 FI970800A FI970800A FI970800A0 FI 970800 A0 FI970800 A0 FI 970800A0 FI 970800 A FI970800 A FI 970800A FI 970800 A FI970800 A FI 970800A FI 970800 A0 FI970800 A0 FI 970800A0
Authority
FI
Finland
Prior art keywords
migraine
indole derivative
derivative salts
salts
indole
Prior art date
Application number
FI970800A
Other languages
English (en)
Swedish (sv)
Other versions
FI970800L (fi
FI113768B (fi
Inventor
Valerie Denise Harding
Ross James Macrae
Ronald James Ogilvie
Original Assignee
Pfizer Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10760474&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI970800(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Res & Dev filed Critical Pfizer Res & Dev
Publication of FI970800A0 publication Critical patent/FI970800A0/fi
Publication of FI970800L publication Critical patent/FI970800L/fi
Application granted granted Critical
Publication of FI113768B publication Critical patent/FI113768B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Toxicology (AREA)
  • Anesthesiology (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Otolaryngology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Reciprocating, Oscillating Or Vibrating Motors (AREA)
FI970800A 1994-08-27 1997-02-26 Migreeninvastaisia indolijohdossuoloja FI113768B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9417310A GB9417310D0 (en) 1994-08-27 1994-08-27 Therapeutic agents
GB9417310 1994-08-27
EP9501914 1995-05-17
PCT/EP1995/001914 WO1996006842A1 (en) 1994-08-27 1995-05-17 Salts of an anti-migraine indole derivative

Publications (3)

Publication Number Publication Date
FI970800A0 true FI970800A0 (fi) 1997-02-26
FI970800L FI970800L (fi) 1997-02-26
FI113768B FI113768B (fi) 2004-06-15

Family

ID=10760474

Family Applications (1)

Application Number Title Priority Date Filing Date
FI970800A FI113768B (fi) 1994-08-27 1997-02-26 Migreeninvastaisia indolijohdossuoloja

Country Status (45)

Country Link
US (2) US6110940A (fi)
EP (1) EP0776323B1 (fi)
JP (1) JP2904588B2 (fi)
KR (1) KR100228952B1 (fi)
CN (1) CN1066727C (fi)
AP (1) AP576A (fi)
AT (1) ATE163182T1 (fi)
AU (1) AU691005B2 (fi)
BG (1) BG61840B1 (fi)
BR (1) BRPI9503812B1 (fi)
CA (1) CA2198599C (fi)
CO (1) CO4410334A1 (fi)
CZ (1) CZ287693B6 (fi)
DE (1) DE69501620T2 (fi)
DK (1) DK0776323T3 (fi)
DZ (1) DZ1923A1 (fi)
EG (1) EG23822A (fi)
ES (1) ES2112650T3 (fi)
FI (1) FI113768B (fi)
GB (1) GB9417310D0 (fi)
GR (1) GR3026475T3 (fi)
HR (1) HRP950460B1 (fi)
HU (1) HU227822B1 (fi)
IL (1) IL115013A (fi)
IS (1) IS1850B (fi)
LV (1) LV11800B (fi)
MA (1) MA23650A1 (fi)
MX (1) MX9701538A (fi)
MY (1) MY113733A (fi)
NO (1) NO311297B1 (fi)
NZ (1) NZ288210A (fi)
OA (1) OA10600A (fi)
PE (1) PE41596A1 (fi)
PL (1) PL180867B1 (fi)
RO (1) RO116400B1 (fi)
RU (1) RU2159241C2 (fi)
SA (1) SA95160156B1 (fi)
SI (1) SI9520091B (fi)
SK (1) SK282922B6 (fi)
TN (1) TNSN95092A1 (fi)
TR (1) TR199501061A2 (fi)
UA (1) UA45980C2 (fi)
WO (1) WO1996006842A1 (fi)
YU (1) YU49287B (fi)
ZA (1) ZA957142B (fi)

Families Citing this family (39)

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GB9420529D0 (en) 1994-10-12 1994-11-30 Pfizer Ltd Indoles
GB9706089D0 (en) * 1997-03-24 1997-05-14 Scherer Ltd R P Pharmaceutical composition
GB9714081D0 (en) * 1997-07-03 1997-09-10 Pfizer Ltd Pharmaceutical compositions
AU724728B2 (en) * 1997-07-03 2000-09-28 Pfizer Inc. Pharmaceutical compositions containing eletriptan hemisulphate and caffeine
GB9816556D0 (en) * 1998-07-30 1998-09-30 Pfizer Ltd Therapy
GB9825988D0 (en) * 1998-11-27 1999-01-20 Pfizer Ltd Indole derivatives
GB9922963D0 (en) * 1999-09-28 1999-12-01 Pfizer Ltd Polymorphic salt
GB9915231D0 (en) 1999-06-29 1999-09-01 Pfizer Ltd Pharmaceutical complex
GB9923314D0 (en) 1999-10-01 1999-12-08 Pfizer Ltd Acylation process
CA2324116A1 (en) * 1999-10-25 2001-04-25 Susan Beth Sobolov-Jaynes Nk-1 receptor antagonists and eletriptan for the treatment of migraine
US7108970B2 (en) 2000-01-07 2006-09-19 Transform Pharmaceuticals, Inc. Rapid identification of conditions, compounds, or compositions that inhibit, prevent, induce, modify, or reverse transitions of physical state
US6977723B2 (en) 2000-01-07 2005-12-20 Transform Pharmaceuticals, Inc. Apparatus and method for high-throughput preparation and spectroscopic classification and characterization of compositions
GB0008563D0 (en) 2000-04-07 2000-05-24 Cambridge Discovery Chemistry Investigating different physical and/or chemical forms of materials
GB0018968D0 (en) * 2000-08-02 2000-09-20 Pfizer Ltd Particulate composition
US20030166704A1 (en) * 2000-12-20 2003-09-04 Pfizer Inc. New process
GB0031094D0 (en) * 2000-12-20 2001-01-31 Pfizer Ltd New Process
US6579898B2 (en) 2001-03-01 2003-06-17 Pfizer Inc. Compositions having improved bioavailability
EP1615635A1 (en) 2003-04-11 2006-01-18 Pfizer Limited Pharmaceutical combination comprising eletriptan and sodium bicarbonate
GB0312478D0 (en) * 2003-05-30 2003-07-09 Pfizer Ltd Improved process
US7132549B2 (en) 2003-05-30 2006-11-07 Pfizer Inc. Process
US6927296B2 (en) 2003-07-23 2005-08-09 Pfizer Inc. Process
GB0317229D0 (en) * 2003-07-23 2003-08-27 Pfizer Ltd Improved process
US7241805B2 (en) 2005-06-27 2007-07-10 Biovail Laboratories, Inc. Modified release formulations of a bupropion salt
RU2313340C1 (ru) * 2006-02-20 2007-12-27 Дмитрий Владимирович Зимин Лекарственное средство, обладающее противомигренозным действием, и способ его изготовления
ATE502921T1 (de) * 2006-10-19 2011-04-15 Auspex Pharmaceuticals Inc Substituierte indole
US20080139510A1 (en) * 2006-12-07 2008-06-12 Abe Rose Treatment of migraine headaches with sublingual amino acids
EP1956018A1 (de) * 2007-02-06 2008-08-13 Boehringer Ingelheim Pharma GmbH & Co. KG Verfahren zur Herstellung eines Benzimidazolderivats
US20080287519A1 (en) * 2007-05-01 2008-11-20 Marioara Mendelovici Amorphous eletriptan hydrobromide and process for preparing it and other forms of eletriptan hydrobromide
EP2038273A1 (en) * 2007-05-29 2009-03-25 Plus Chemicals B.V. A process for preparing 5-bromo-3-[(r)-1-methyl-pyrrolidin-2-ylmethyl]-1h-indole
EP2225224A2 (en) * 2007-12-17 2010-09-08 Actavis Group PTC EHF Novel hemioxalate salt of eletriptan
WO2009142771A2 (en) * 2008-05-22 2009-11-26 Plus Chemicals, S.A. Salts of (r)-5-(2-phenylsulphonylethenyl)-3-(n- methylpyrrolidin-2-ylmethyl)-1h-indole, 5-bromo-3-[(r)-1- methyl-pyrrolidin-2- ylmethyl]-1h-indole and of eletriptan
CA2731041C (en) 2008-08-07 2016-09-06 Biovail Laboratories International Srl Bupropion hydrobromide polymorphs
US20120027816A1 (en) * 2009-02-25 2012-02-02 Actavis Group Ptc Ehf Highly pure eletriptan or a pharmaceutically acceptable salt thereof substantially free of eletriptan n-oxide impurity
WO2010116386A2 (en) * 2009-04-08 2010-10-14 Biophore India Pharmaceuticals Pvt. Ltd. Novel polymorph of eletriptan hydrobromide and process for the preparation thereof
IT1393700B1 (it) 2009-04-22 2012-05-08 F S I Fabbrica Italiana Sint Sintesi di 3-{[(2r)-1-metilpirrolidin-2-il]metil}-5-[2-(fenilsulfonil)etil]-1h-indolo
WO2011004391A2 (en) 2009-06-25 2011-01-13 Matrix Laboratories Ltd An improved process for the preparation of eletriptan and its salt thereof
US8754239B2 (en) 2010-01-19 2014-06-17 Sms Pharmaceuticals Limited Process for preparing eletriptan hydrobromide having α-form
WO2014063752A1 (en) 2012-10-26 2014-05-01 Synthon Bv Process for making crystalline form alpha of eletriptan hydrobromide
JP2019502761A (ja) 2016-01-21 2019-01-31 ラボラトリオス レヴィ エセエレ ((r)−3−[(−1−メチルピロリジン−2−イル)メチル]−5−(2−フェニルスルホニルエチル)−1h−インドールを作製する方法

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US5545644A (en) * 1990-10-15 1996-08-13 Pfizer Inc. Indole derivatives
US5578612A (en) * 1990-10-15 1996-11-26 Pfizer Inc. Indole derivatives
US5208248A (en) * 1991-01-11 1993-05-04 Merck Sharpe & Dohme, Ltd. Indazole-substituted five-membered heteroaromatic compounds
SK278998B6 (sk) * 1991-02-01 1998-05-06 Merck Sharp & Dohme Limited Deriváty imidazolu, triazolu a tetrazolu, spôsob i
ATE190608T1 (de) * 1991-11-25 2000-04-15 Pfizer 5-(hetero- oder carbocyclylamino)-indol derivate, deren herstellung und deren verwendung als 5-ht1 agonisten
GB9201038D0 (en) * 1992-01-16 1992-03-11 Glaxo Group Ltd Chemical compounds
US5409941A (en) * 1992-02-03 1995-04-25 Pfizer Inc. 5-heteroyl indole derivatives
TW288010B (fi) * 1992-03-05 1996-10-11 Pfizer
UA27467C2 (uk) * 1992-04-07 2000-09-15 Пфайзер Інк. ПОХІДНІ ІНДОЛУ ЯК 5-НТ<sub>1</sub> АГОНІСТИ ТА ПРОМІЖНІ СПОЛУКИ
CZ282653B6 (cs) * 1992-04-10 1997-08-13 Pfizer Inc. Acylaminoindolové deriváty představující 5-HT1 agonisty, způsob jejich přípravy, farmaceutické prostředky obsahující tyto látky, jejich použití a meziprodukty postupu přípravy
GB9207930D0 (en) * 1992-04-10 1992-05-27 Pfizer Ltd Indoles
GB9208161D0 (en) * 1992-04-14 1992-05-27 Pfizer Ltd Indoles
GB9210400D0 (en) * 1992-05-15 1992-07-01 Merck Sharp & Dohme Therapeutic agents
FR2701026B1 (fr) * 1993-02-02 1995-03-31 Adir Nouveaux dérivés de l'indole, de l'indazole et du benzisoxazole, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
EP0695301B1 (en) * 1993-04-22 1996-10-30 Pfizer Limited Indole derivatives as 5-ht1-like agonists for use in migraine
AP486A (en) * 1993-04-27 1996-04-16 Pfizer Indole derivatives.
DK0716649T3 (da) * 1993-08-31 1999-02-08 Pfizer 5-Arylindolderivater

Also Published As

Publication number Publication date
KR100228952B1 (ko) 1999-11-01
NO311297B1 (no) 2001-11-12
MX9701538A (es) 1997-05-31
HU227822B1 (en) 2012-03-28
SA95160156B1 (ar) 2005-05-30
DE69501620T2 (de) 1998-07-02
DK0776323T3 (da) 1998-03-30
ES2112650T3 (es) 1998-04-01
PL180867B1 (pl) 2001-04-30
LV11800B (en) 1997-10-20
SI9520091B (sl) 2004-10-31
AP576A (en) 1997-03-20
HRP950460B1 (en) 2000-02-29
IL115013A (en) 2000-11-21
AU691005B2 (en) 1998-05-07
IS4401A (is) 1996-12-19
CZ287693B6 (en) 2001-01-17
YU56995A (sh) 1998-07-10
CA2198599C (en) 2000-06-06
SK282922B6 (sk) 2003-01-09
CA2198599A1 (en) 1996-03-07
US6110940A (en) 2000-08-29
NO970861D0 (no) 1997-02-26
JPH09512283A (ja) 1997-12-09
RU2159241C2 (ru) 2000-11-20
NO970861L (no) 1997-02-26
NZ288210A (en) 1998-01-26
RO116400B1 (ro) 2001-01-30
US6380226B1 (en) 2002-04-30
PL318319A1 (en) 1997-06-09
EP0776323B1 (en) 1998-02-11
CZ56397A3 (cs) 1998-05-13
SK24897A3 (en) 1998-08-05
IL115013A0 (en) 1995-12-08
FI970800L (fi) 1997-02-26
ZA957142B (en) 1997-02-25
SI9520091A (sl) 1998-02-28
DZ1923A1 (fr) 2002-02-17
YU49287B (sh) 2005-03-15
FI113768B (fi) 2004-06-15
TNSN95092A1 (fr) 1996-02-06
BR9503812A (pt) 1996-04-16
BG101250A (en) 1997-09-30
EP0776323A1 (en) 1997-06-04
LV11800A (lv) 1997-06-20
AU2735295A (en) 1996-03-22
JP2904588B2 (ja) 1999-06-14
MY113733A (en) 2002-05-31
MA23650A1 (fr) 1996-04-01
OA10600A (en) 2000-04-06
HUT77310A (hu) 1998-03-30
KR970705557A (ko) 1997-10-09
PE41596A1 (es) 1996-10-12
HRP950460A2 (en) 1997-08-31
CN1066727C (zh) 2001-06-06
TR199501061A2 (tr) 1996-06-21
BG61840B1 (bg) 1998-07-31
IS1850B (is) 2003-02-07
GR3026475T3 (en) 1998-06-30
CN1155886A (zh) 1997-07-30
WO1996006842A1 (en) 1996-03-07
DE69501620D1 (de) 1998-03-19
CO4410334A1 (es) 1997-01-09
AP9500754A0 (en) 1995-07-31
BRPI9503812B1 (pt) 2017-04-18
UA45980C2 (uk) 2002-05-15
GB9417310D0 (en) 1994-10-19
EG23822A (en) 2007-09-19
ATE163182T1 (de) 1998-02-15

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