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ECSP10010270A - Anticuerpos bivalentes biespecíficos - Google Patents

Anticuerpos bivalentes biespecíficos

Info

Publication number
ECSP10010270A
ECSP10010270A EC2010010270A ECSP10010270A ECSP10010270A EC SP10010270 A ECSP10010270 A EC SP10010270A EC 2010010270 A EC2010010270 A EC 2010010270A EC SP10010270 A ECSP10010270 A EC SP10010270A EC SP10010270 A ECSP10010270 A EC SP10010270A
Authority
EC
Ecuador
Prior art keywords
biven
specific antibodies
elaboration
present
bivalent antibodies
Prior art date
Application number
EC2010010270A
Other languages
English (en)
Inventor
Wolfgang Schaefer
Christian Klein
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ECSP10010270A publication Critical patent/ECSP10010270A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invención está relacionada con nuevos anticuerpos bivalentes biespecíficos con intercambio de dominios, su elaboración y su utilización.
EC2010010270A 2007-12-21 2010-06-18 Anticuerpos bivalentes biespecíficos ECSP10010270A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07024864 2007-12-21

Publications (1)

Publication Number Publication Date
ECSP10010270A true ECSP10010270A (es) 2010-07-30

Family

ID=39093026

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2010010270A ECSP10010270A (es) 2007-12-21 2010-06-18 Anticuerpos bivalentes biespecíficos

Country Status (22)

Country Link
US (5) US20090162359A1 (es)
EP (1) EP2225279B1 (es)
JP (1) JP5281097B2 (es)
KR (1) KR101249607B1 (es)
CN (1) CN101903404B (es)
AR (1) AR071547A1 (es)
AU (1) AU2008340693A1 (es)
BR (1) BRPI0821791B1 (es)
CA (1) CA2709023C (es)
CL (1) CL2008003781A1 (es)
CO (1) CO6280542A2 (es)
CR (1) CR11460A (es)
EC (1) ECSP10010270A (es)
ES (1) ES2469791T3 (es)
IL (1) IL206161A0 (es)
MA (1) MA31904B1 (es)
MX (1) MX2010006396A (es)
NZ (1) NZ585627A (es)
PE (1) PE20091172A1 (es)
RU (1) RU2587616C2 (es)
TW (1) TWI359027B (es)
WO (1) WO2009080252A1 (es)

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