BRPI0916915A2 - anticorpos anti-il-17a/f de reatividade cruzada e biespecíficos - Google Patents

anticorpos anti-il-17a/f de reatividade cruzada e biespecíficos

Info

Publication number: BRPI0916915A2
Authority: BR; Brazil
Prior art keywords: antibodies; reactive anti; bispecific cross; bispecific; cross
Prior art date: 2008-08-29

Application number

BRPI0916915A

Other languages

English (en)

Inventor

Scott Stawicki

Wenjun Ouyang

Yan Helen Hu

Yan Wu

Yongmei Chen

Original Assignee

Genentech Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-08-29

Filing date

2009-08-28

Publication date

2015-11-24

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41497126&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0916915(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2009-08-28 Application filed by Genentech Inc filed Critical Genentech Inc

2015-11-24 Publication of BRPI0916915A2 publication Critical patent/BRPI0916915A2/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Pulmonology (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Diabetes (AREA)
Virology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Biomedical Technology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Neurology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Orthopedic Medicine & Surgery (AREA)
Neurosurgery (AREA)
Tropical Medicine & Parasitology (AREA)
Hematology (AREA)
Biotechnology (AREA)
Dermatology (AREA)
Pain & Pain Management (AREA)
Zoology (AREA)
Endocrinology (AREA)
Wood Science & Technology (AREA)

BRPI0916915A 2008-08-29 2009-08-28 anticorpos anti-il-17a/f de reatividade cruzada e biespecíficos BRPI0916915A2 (pt)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US9321208P	2008-08-29	2008-08-29
US11264408P	2008-11-07	2008-11-07
US16470909P	2009-03-30	2009-03-30
PCT/US2009/055420 WO2010025400A2 (en)	2008-08-29	2009-08-28	Cross-reactive and bispecific anti-el 17a/f antibodies

Publications (1)

Publication Number	Publication Date
BRPI0916915A2 true BRPI0916915A2 (pt)	2015-11-24

Family

ID=41497126

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0916915A BRPI0916915A2 (pt)	2008-08-29	2009-08-28	anticorpos anti-il-17a/f de reatividade cruzada e biespecíficos

Country Status (17)

Country	Link
US (2)	US8790642B2 (pt)
EP (2)	EP2321349A2 (pt)
JP (1)	JP2012501186A (pt)
KR (1)	KR20110055692A (pt)
CN (2)	CN103360493A (pt)
AR (1)	AR073232A1 (pt)
AU (2)	AU2009285616B2 (pt)
BR (1)	BRPI0916915A2 (pt)
CA (1)	CA2732642A1 (pt)
CL (1)	CL2011000397A1 (pt)
IL (1)	IL210942A0 (pt)
MX (1)	MX337684B (pt)
PE (1)	PE20110801A1 (pt)
SG (1)	SG10201507009YA (pt)
TW (1)	TW201012478A (pt)
WO (1)	WO2010025400A2 (pt)
ZA (1)	ZA201100749B (pt)

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ES2751414T5 (es)	2003-07-08	2024-04-23	Novartis Pharma Ag	Anticuerpos antagonistas a polipéptidos heterólogos IL-17 A/F
US20090317400A1 (en)	2008-05-05	2009-12-24	Krzysztof Masternak	Anti-IL 17A/IL-17F Cross-Reactive Antibodies and Methods of Use Thereof
US8790642B2 (en)	2008-08-29	2014-07-29	Genentech, Inc.	Cross-reactive and bispecific anti-IL-17A/F antibodies
RU2605318C2 (ru)	2009-05-05	2016-12-20	Новиммун С.А.	Анти-il-17f антитела и способы их применения
EP3546483A1 (en)	2010-05-20	2019-10-02	Ablynx N.V.	Biological materials related to her3
EP3176184B1 (en)	2010-11-10	2020-02-19	F. Hoffmann-La Roche AG	Anti-bace1 antibodies for neural disease immunotherapy
GB201100282D0 (en)	2011-01-07	2011-02-23	Ucb Pharma Sa	Biological methods
US10208349B2 (en)	2011-01-07	2019-02-19	Ucb Biopharma Sprl	Lipocalin 2 as a biomarker for IL-17 inhibitor therapy efficacy
CN103384682B (zh)	2011-01-14	2017-04-12	Ucb医药有限公司	结合il‑17a和il‑17f的抗体分子
UA117218C2 (uk) *	2011-05-05	2018-07-10	Мерк Патент Гмбх	Поліпептид, спрямований проти il-17a, il-17f та/або il17-a/f
CN103308697B (zh) *	2013-06-09	2014-11-26	卫生部北京医院	检测抗丙型肝炎病毒编码的非结构蛋白ns3和ns5的天然双特异性抗体的试剂盒
JP6546178B2 (ja)	2013-09-13	2019-07-17	ジェネンテック，インコーポレイテッド	細胞株中の宿主細胞タンパク質及び組換えポリペプチド産物を検出及び定量化するための組成物並びに方法
EP4331605A3 (en)	2013-09-13	2024-05-22	F. Hoffmann-La Roche AG	Methods and compositions comprising purified recombinant polypeptides
CN103554264B (zh) *	2013-11-05	2015-08-12	哈尔滨博翱生物医药技术开发有限公司	针对IL-1β和IL-17A的双特异性抗体及其应用
TWI713453B (zh)	2014-06-23	2020-12-21	美商健生生物科技公司	干擾素α及ω抗體拮抗劑
CN107148283A (zh) *	2014-10-31	2017-09-08	豪夫迈·罗氏有限公司	抗il‑17a和il‑17f交叉反应性抗体变体、包含其的组合物及其制备和使用方法
US10882920B2 (en)	2014-11-19	2021-01-05	Genentech, Inc.	Antibodies against BACE1 and use thereof for neural disease immunotherapy
US11008403B2 (en)	2014-11-19	2021-05-18	Genentech, Inc.	Anti-transferrin receptor / anti-BACE1 multispecific antibodies and methods of use
AR103173A1 (es)	2014-12-22	2017-04-19	Novarits Ag	Productos farmacéuticos y composiciones líquidas estables de anticuerpos il-17
SG11201802887PA (en) *	2015-10-27	2018-05-30	Ucb Biopharma Sprl	Methods of treatment using anti-il-17a/f antibodies
KR20200083996A (ko)	2017-11-02	2020-07-09	노파르티스 아게	인터류킨-17(il-17)을 사용하여 건병증을 치료하는 방법
KR20250174989A (ko) *	2018-03-27	2025-12-15	아즈테라피즈 인코포레이티드	신경변성 질환을 치료하기 위한 CAR-Treg-기반 요법
EP4433503A2 (en) *	2021-11-18	2024-09-25	Twist Bioscience Corporation	Cytokine variant antibodies and methods of use
CN119630422A (zh)	2022-05-16	2025-03-14	诺华股份有限公司	使用白细胞介素-17(il-17)拮抗剂治疗巨细胞动脉炎的方法
KR20250011948A (ko)	2022-05-18	2025-01-22	노파르티스 아게	인터류킨-17(il-17) 길항제를 사용하여 건병증을 선택적으로 치료하는 방법
EP4393948A1 (en) *	2022-12-28	2024-07-03	Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.	Therapeutic vhh antibodies cross-neutralizing the il-17a and il-17f homodimers as well as the il-17af heterodimer

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- 2009-08-28 AU AU2009285616A patent/AU2009285616B2/en not_active Ceased
- 2009-08-28 EP EP09792076A patent/EP2321349A2/en not_active Withdrawn
- 2009-08-28 KR KR1020117006871A patent/KR20110055692A/ko not_active Ceased
- 2009-08-28 CN CN2013102735648A patent/CN103360493A/zh active Pending
- 2009-08-28 AR ARP090103325A patent/AR073232A1/es unknown
- 2009-08-28 PE PE2011000189A patent/PE20110801A1/es not_active Application Discontinuation
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- 2009-08-28 BR BRPI0916915A patent/BRPI0916915A2/pt not_active IP Right Cessation
- 2009-08-28 TW TW098129172A patent/TW201012478A/zh unknown
- 2009-08-28 JP JP2011525247A patent/JP2012501186A/ja active Pending
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2011
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2014
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Publication number	Publication date
WO2010025400A2 (en)	2010-03-04
MX2011002073A (es)	2011-03-29
US20100055103A1 (en)	2010-03-04
KR20110055692A (ko)	2011-05-25
AU2009285616B2 (en)	2014-11-20
SG10201507009YA (en)	2015-10-29
PE20110801A1 (es)	2011-10-31
WO2010025400A3 (en)	2010-07-15
AU2009285616A1 (en)	2010-03-04
AU2015200790A1 (en)	2015-03-05
AR073232A1 (es)	2010-10-20
CL2011000397A1 (es)	2012-03-30
CN102137872A (zh)	2011-07-27
TW201012478A (en)	2010-04-01
JP2012501186A (ja)	2012-01-19
US8790642B2 (en)	2014-07-29
ZA201100749B (en)	2012-04-25
CN103360493A (zh)	2013-10-23
US9512217B2 (en)	2016-12-06
IL210942A0 (en)	2011-04-28
US20140314763A1 (en)	2014-10-23
MX337684B (es)	2016-03-15
EP3211008A1 (en)	2017-08-30
CA2732642A1 (en)	2010-03-04
EP2321349A2 (en)	2011-05-18

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