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MX2010005888A - Anticuerpos bivalentes biespecificos. - Google Patents

Anticuerpos bivalentes biespecificos.

Info

Publication number
MX2010005888A
MX2010005888A MX2010005888A MX2010005888A MX2010005888A MX 2010005888 A MX2010005888 A MX 2010005888A MX 2010005888 A MX2010005888 A MX 2010005888A MX 2010005888 A MX2010005888 A MX 2010005888A MX 2010005888 A MX2010005888 A MX 2010005888A
Authority
MX
Mexico
Prior art keywords
bivalent
bispecific antibodies
manufacture
relates
present
Prior art date
Application number
MX2010005888A
Other languages
English (en)
Inventor
Wolfgang Schaefer
Christian Klein
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39687068&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2010005888(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MX2010005888A publication Critical patent/MX2010005888A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invención se refiere a nuevos anticuerpos bivalentes biespecíficos de dominio intercambiados, su obtención y uso.
MX2010005888A 2007-12-21 2008-12-16 Anticuerpos bivalentes biespecificos. MX2010005888A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07024867 2007-12-21
PCT/EP2008/010702 WO2009080251A1 (en) 2007-12-21 2008-12-16 Bivalent, bispecific antibodies

Publications (1)

Publication Number Publication Date
MX2010005888A true MX2010005888A (es) 2010-06-22

Family

ID=39687068

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010005888A MX2010005888A (es) 2007-12-21 2008-12-16 Anticuerpos bivalentes biespecificos.

Country Status (17)

Country Link
US (1) US9266967B2 (es)
EP (1) EP2231709B1 (es)
JP (1) JP5281096B2 (es)
KR (1) KR101265912B1 (es)
CN (1) CN101896504B (es)
AR (1) AR069776A1 (es)
AU (1) AU2008340692A1 (es)
BR (1) BRPI0821375B8 (es)
CA (1) CA2709345C (es)
CL (1) CL2008003779A1 (es)
ES (1) ES2468265T3 (es)
IL (1) IL205285A0 (es)
MX (1) MX2010005888A (es)
PE (1) PE20091340A1 (es)
RU (1) RU2547615C2 (es)
TW (1) TW200927171A (es)
WO (1) WO2009080251A1 (es)

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