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MX2010005292A - Inhibidores de la replicacion del virus de la inmunodeficiencia humana. - Google Patents

Inhibidores de la replicacion del virus de la inmunodeficiencia humana.

Info

Publication number
MX2010005292A
MX2010005292A MX2010005292A MX2010005292A MX2010005292A MX 2010005292 A MX2010005292 A MX 2010005292A MX 2010005292 A MX2010005292 A MX 2010005292A MX 2010005292 A MX2010005292 A MX 2010005292A MX 2010005292 A MX2010005292 A MX 2010005292A
Authority
MX
Mexico
Prior art keywords
sup
immunodeficiency virus
human immunodeficiency
inhibitors
virus replication
Prior art date
Application number
MX2010005292A
Other languages
English (en)
Inventor
Bruno Simoneau
Serge Landry
Christian Brochu
Stephen Kawai
Youla S Tsantrizos
Rebekah J Carson
Lee Fader
Sebastien Morin
Mathieu Parisien
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of MX2010005292A publication Critical patent/MX2010005292A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se refiere a compuestos de fórmula (I): (ver fórmula I) en la que c, X, Y, R2, R3, R4 y R6 se definen en la presente memoria, composiciones y usos de los mismos, una infección por el virus de inmunodeficiencia humana (VIH). En particular, la presente invención proporciona nuevos inhibidores de la integrasa de VIH, composiciones farmacéuticas que contiene dichos compuestos y métodos para usar estos compuestos en el tratamiento de una infección por VIH.
MX2010005292A 2007-11-15 2008-11-03 Inhibidores de la replicacion del virus de la inmunodeficiencia humana. MX2010005292A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98834207P 2007-11-15 2007-11-15
PCT/CA2008/001935 WO2009062288A1 (en) 2007-11-15 2008-11-03 Inhibitors of human immunodeficiency virus replication

Publications (1)

Publication Number Publication Date
MX2010005292A true MX2010005292A (es) 2010-07-05

Family

ID=40638277

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010005292A MX2010005292A (es) 2007-11-15 2008-11-03 Inhibidores de la replicacion del virus de la inmunodeficiencia humana.

Country Status (18)

Country Link
US (1) US7956068B2 (es)
EP (2) EP2220095B1 (es)
JP (1) JP5269085B2 (es)
KR (1) KR20100108337A (es)
CN (1) CN102124011A (es)
AR (1) AR069334A1 (es)
AU (1) AU2008323561B2 (es)
BR (1) BRPI0819328A8 (es)
CA (1) CA2705312C (es)
CL (1) CL2008003405A1 (es)
ES (1) ES2402322T3 (es)
IL (1) IL205746A0 (es)
MX (1) MX2010005292A (es)
NZ (1) NZ585297A (es)
RU (1) RU2503679C2 (es)
TW (1) TW200920363A (es)
WO (1) WO2009062288A1 (es)
ZA (1) ZA201003305B (es)

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EP3116879A1 (en) 2014-02-18 2017-01-18 VIIV Healthcare UK (No.5) Limited Imidazopyrimidine macrocycles as inhibitors of human immunodeficiency virus replication
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Also Published As

Publication number Publication date
CA2705312A1 (en) 2009-05-22
ES2402322T3 (es) 2013-04-30
RU2503679C2 (ru) 2014-01-10
BRPI0819328A8 (pt) 2016-02-10
TW200920363A (en) 2009-05-16
EP2574610A1 (en) 2013-04-03
IL205746A0 (en) 2010-11-30
JP2011503117A (ja) 2011-01-27
EP2220095A1 (en) 2010-08-25
US20100305115A1 (en) 2010-12-02
AR069334A1 (es) 2010-01-13
US7956068B2 (en) 2011-06-07
WO2009062288A1 (en) 2009-05-22
RU2010123989A (ru) 2011-12-20
ZA201003305B (en) 2011-03-30
EP2220095B1 (en) 2013-01-02
CL2008003405A1 (es) 2010-02-12
JP5269085B2 (ja) 2013-08-21
EP2220095A4 (en) 2011-01-26
BRPI0819328A2 (pt) 2015-05-12
AU2008323561B2 (en) 2013-07-18
NZ585297A (en) 2012-06-29
KR20100108337A (ko) 2010-10-06
AU2008323561A1 (en) 2009-05-22
CA2705312C (en) 2013-06-25
CN102124011A (zh) 2011-07-13

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