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BRPI0819328A8 - Compostos inibidores de replicação de vírus da imunodeficiência humana, composição farmacêutica e uso dos ditos compostos - Google Patents

Compostos inibidores de replicação de vírus da imunodeficiência humana, composição farmacêutica e uso dos ditos compostos

Info

Publication number
BRPI0819328A8
BRPI0819328A8 BRPI0819328A BRPI0819328A BRPI0819328A8 BR PI0819328 A8 BRPI0819328 A8 BR PI0819328A8 BR PI0819328 A BRPI0819328 A BR PI0819328A BR PI0819328 A BRPI0819328 A BR PI0819328A BR PI0819328 A8 BRPI0819328 A8 BR PI0819328A8
Authority
BR
Brazil
Prior art keywords
compounds
pharmaceutical composition
immunodeficiency virus
human immunodeficiency
virus replication
Prior art date
Application number
BRPI0819328A
Other languages
English (en)
Inventor
J Carson Rebekah
Fader Lee
Kawai Stephen
Landry Serge
S Tsantrizos Youla
Brochu Christian
Morin Sebastien
Parisien Mathieu
Simoneau Bruno
Original Assignee
Boehringer Ingelheim Int
Gilead Sciences Ltd
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int, Gilead Sciences Ltd, Gilead Sciences Inc filed Critical Boehringer Ingelheim Int
Publication of BRPI0819328A2 publication Critical patent/BRPI0819328A2/pt
Publication of BRPI0819328A8 publication Critical patent/BRPI0819328A8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

COMPOSTOS INIBIDORES DE REPLICAÇÃO DE VÍRUS DA IMUNODEFICIÊNCIA HUMANA, COMPOSIÇÃO FARMACÊUTICA E USO DOS DITOS COMPOSTOS. A presente invenção refere-se a compostos de fórmula |:(1) em que c, X, Y, R2, R3, R4 e R6 são definidos aqui, que são úteis como inibidores de replicação de HIV.
BRPI0819328A 2007-11-15 2008-11-03 Compostos inibidores de replicação de vírus da imunodeficiência humana, composição farmacêutica e uso dos ditos compostos BRPI0819328A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98834207P 2007-11-15 2007-11-15
PCT/CA2008/001935 WO2009062288A1 (en) 2007-11-15 2008-11-03 Inhibitors of human immunodeficiency virus replication

Publications (2)

Publication Number Publication Date
BRPI0819328A2 BRPI0819328A2 (pt) 2015-05-12
BRPI0819328A8 true BRPI0819328A8 (pt) 2016-02-10

Family

ID=40638277

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0819328A BRPI0819328A8 (pt) 2007-11-15 2008-11-03 Compostos inibidores de replicação de vírus da imunodeficiência humana, composição farmacêutica e uso dos ditos compostos

Country Status (18)

Country Link
US (1) US7956068B2 (pt)
EP (2) EP2220095B1 (pt)
JP (1) JP5269085B2 (pt)
KR (1) KR20100108337A (pt)
CN (1) CN102124011A (pt)
AR (1) AR069334A1 (pt)
AU (1) AU2008323561B2 (pt)
BR (1) BRPI0819328A8 (pt)
CA (1) CA2705312C (pt)
CL (1) CL2008003405A1 (pt)
ES (1) ES2402322T3 (pt)
IL (1) IL205746A0 (pt)
MX (1) MX2010005292A (pt)
NZ (1) NZ585297A (pt)
RU (1) RU2503679C2 (pt)
TW (1) TW200920363A (pt)
WO (1) WO2009062288A1 (pt)
ZA (1) ZA201003305B (pt)

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US9834566B2 (en) 2014-02-18 2017-12-05 VIIV Healthcare UK (No.5) Limited Pyrazolopyrimidine macrocycles as inhibitors of human immunodeficiency virus replication
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Also Published As

Publication number Publication date
AR069334A1 (es) 2010-01-13
JP2011503117A (ja) 2011-01-27
EP2220095B1 (en) 2013-01-02
RU2010123989A (ru) 2011-12-20
ES2402322T3 (es) 2013-04-30
EP2574610A1 (en) 2013-04-03
TW200920363A (en) 2009-05-16
EP2220095A4 (en) 2011-01-26
IL205746A0 (en) 2010-11-30
RU2503679C2 (ru) 2014-01-10
US20100305115A1 (en) 2010-12-02
MX2010005292A (es) 2010-07-05
CA2705312A1 (en) 2009-05-22
ZA201003305B (en) 2011-03-30
EP2220095A1 (en) 2010-08-25
AU2008323561A1 (en) 2009-05-22
BRPI0819328A2 (pt) 2015-05-12
KR20100108337A (ko) 2010-10-06
US7956068B2 (en) 2011-06-07
CN102124011A (zh) 2011-07-13
WO2009062288A1 (en) 2009-05-22
AU2008323561B2 (en) 2013-07-18
CA2705312C (en) 2013-06-25
CL2008003405A1 (es) 2010-02-12
NZ585297A (en) 2012-06-29
JP5269085B2 (ja) 2013-08-21

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Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.