UA85546C2 - Method for treatment and/or prevention of arrhythmic events - Google Patents
Method for treatment and/or prevention of arrhythmic eventsInfo
- Publication number
- UA85546C2 UA85546C2 UAA200505967A UA2005005967A UA85546C2 UA 85546 C2 UA85546 C2 UA 85546C2 UA A200505967 A UAA200505967 A UA A200505967A UA 2005005967 A UA2005005967 A UA 2005005967A UA 85546 C2 UA85546 C2 UA 85546C2
- Authority
- UA
- Ukraine
- Prior art keywords
- treatment
- arrhythmic events
- diazabicyclo
- prevention
- human patients
- Prior art date
Links
- 238000011282 treatment Methods 0.000 title abstract 3
- 230000002763 arrhythmic effect Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title 1
- 206010003658 Atrial Fibrillation Diseases 0.000 abstract 2
- BKIMMITUMNQMOS-UHFFFAOYSA-N nonane Chemical class CCCCCCCCC BKIMMITUMNQMOS-UHFFFAOYSA-N 0.000 abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 229940127557 pharmaceutical product Drugs 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 230000033764 rhythmic process Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- CTIRHWCPXYGDGF-HDICACEKSA-N tedisamil Chemical compound [H][C@]12CN(CC3CC3)C[C@]([H])(CN(CC3CC3)C1)C21CCCC1 CTIRHWCPXYGDGF-HDICACEKSA-N 0.000 abstract 1
- 229960002926 tedisamil Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4747—Quinolines; Isoquinolines spiro-condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
Abstract
Данное изобретение относится к применению производных 3,7-диазабицикло[3.3.1]нонана, преимущественно производных 9,9-алкилен-3,7-диазабицикло[3.3.1]нонана и предпочтительнее - применения тедисамила и его физиологически приемлемых кислотно-аддитивных солей и/или сольватов в форме жидкого фармацевтического препарата для лечения и/или профилактики аритмических приступов у человека, преимущественно при конверсии начальной фибрилляции предсердий (Afib) или трепетания в нормальный синусовый ритм (NSR) у пациентов. Кроме того, изобретение относится к способу лечения и фармацевтическим препаратам.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42679502P | 2002-11-18 | 2002-11-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA85546C2 true UA85546C2 (en) | 2009-02-10 |
Family
ID=32326429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200505967A UA85546C2 (en) | 2002-11-18 | 2003-11-17 | Method for treatment and/or prevention of arrhythmic events |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US7087620B2 (ru) |
| EP (1) | EP1565239B8 (ru) |
| JP (1) | JP2006510613A (ru) |
| KR (1) | KR101059330B1 (ru) |
| CN (1) | CN1726062A (ru) |
| AR (1) | AR042199A1 (ru) |
| AT (1) | ATE501758T1 (ru) |
| AU (1) | AU2003296580B8 (ru) |
| BR (1) | BR0316383A (ru) |
| CA (1) | CA2506083A1 (ru) |
| DE (1) | DE60336417D1 (ru) |
| IL (1) | IL168630A (ru) |
| MX (1) | MXPA05005344A (ru) |
| NO (1) | NO20053010L (ru) |
| RU (1) | RU2358732C2 (ru) |
| SA (1) | SA04250023B1 (ru) |
| TW (1) | TW200418468A (ru) |
| UA (1) | UA85546C2 (ru) |
| WO (1) | WO2004045591A2 (ru) |
| ZA (1) | ZA200504049B (ru) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200418468A (en) * | 2002-11-18 | 2004-10-01 | Solvay Pharm Gmbh | Liquid pharmaceutical formulations containing 3,7-diazabicyclo[3,3,1]nonane compounds and method of treatments relating to anti-arrhytmic events |
| US20050054667A1 (en) * | 2003-07-21 | 2005-03-10 | Solvay Pharmaceuticals Gmbh | Method of treating or inhibiting anti-arrhythmic events in male human patients |
| AU2004260624A1 (en) * | 2003-07-21 | 2005-02-10 | Solvay Pharmaceuticals Gmbh | Use of 3,7-diazabicyclo`3, 3,1 !nonane compounds for the treatment and/or prophylaxis of anti-arrhythmic events in male human patients |
| JPWO2007023775A1 (ja) * | 2005-08-23 | 2009-02-26 | アステラス製薬株式会社 | 心房細動治療剤 |
| EP2149370A1 (en) * | 2008-07-31 | 2010-02-03 | Neuroscienze Pharmaness S.C. A R.L. | Diazabicyclic compounds and microemulsions thereof |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3361244D1 (de) * | 1982-01-29 | 1986-01-02 | Ici Plc | Alkanolamine derivatives |
| DE3234697A1 (de) * | 1982-09-18 | 1984-03-22 | Kali-Chemie Pharma Gmbh, 3000 Hannover | Neue diazabicyclo-(3,3,1)-nonane |
| PT88381B (pt) * | 1987-09-09 | 1995-07-06 | Kali Chemie Pharma Gmbh | Processo para a preparacao de novos compostos 3,7-diazabiciclo{3,3,1} nonano, e de composicoes farmaceuticas que contem estes compostos |
| DE4019080A1 (de) * | 1990-06-15 | 1991-12-19 | Kali Chemie Pharma Gmbh | Neue 3,7-diazabicycolo (3,3,1)nonan-verbindungen enthaltende arzneimittel |
| DE4139763A1 (de) * | 1991-12-03 | 1993-06-09 | Kali-Chemie Pharma Gmbh, 3000 Hannover, De | Kristalline fumarsaure salze von 9,9-alkylen-3,7-diazabicyclononan-verbindungen und diese verbindungen enthaltende arzneimittel |
| DE4402931A1 (de) * | 1994-02-01 | 1995-08-03 | Kali Chemie Pharma Gmbh | Neue 3-Phenylsulfonyl-3,7-diazabicyclo[3,3,1] nonan-Verbindungen enthaltende Arzneimittel |
| DE4402933A1 (de) * | 1994-02-01 | 1995-08-03 | Kali Chemie Pharma Gmbh | Neue 3-Benzoyl-3,7-diazabicyclo[3,3,1] nonan-Verbindungen enthaltende Arzneimittel |
| US5576349A (en) * | 1995-11-30 | 1996-11-19 | The General Hospital Corporation | Retionoic acid treatment of cardiac arrhythmia |
| US6026817A (en) * | 1996-11-14 | 2000-02-22 | Clemens; Anton H. | Method of treating the syndrome of coronary heart disease risk factors in humans |
| SE9704709D0 (sv) * | 1997-12-17 | 1997-12-17 | Astra Ab | Pharmaceutically active compounds |
| US6790463B2 (en) * | 2001-03-30 | 2004-09-14 | Robert F. Hofmann | Uses of targeted oxidative therapeutic formulation in arteriosclerosis |
| DE10131217A1 (de) * | 2001-06-28 | 2003-01-09 | Solvay Pharm Gmbh | 3-Phenyl-3,7-diazabicyclo 3,3,1 nonan-Verbindungen sowie Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
| TW200418468A (en) * | 2002-11-18 | 2004-10-01 | Solvay Pharm Gmbh | Liquid pharmaceutical formulations containing 3,7-diazabicyclo[3,3,1]nonane compounds and method of treatments relating to anti-arrhytmic events |
-
2003
- 2003-11-13 TW TW092131744A patent/TW200418468A/zh unknown
- 2003-11-17 AU AU2003296580A patent/AU2003296580B8/en not_active Ceased
- 2003-11-17 KR KR1020057008973A patent/KR101059330B1/ko not_active Expired - Fee Related
- 2003-11-17 AT AT03811379T patent/ATE501758T1/de not_active IP Right Cessation
- 2003-11-17 UA UAA200505967A patent/UA85546C2/ru unknown
- 2003-11-17 DE DE60336417T patent/DE60336417D1/de not_active Expired - Lifetime
- 2003-11-17 CA CA002506083A patent/CA2506083A1/en not_active Abandoned
- 2003-11-17 MX MXPA05005344A patent/MXPA05005344A/es unknown
- 2003-11-17 WO PCT/EP2003/012844 patent/WO2004045591A2/en not_active Ceased
- 2003-11-17 RU RU2005119280/15A patent/RU2358732C2/ru not_active IP Right Cessation
- 2003-11-17 CN CNA2003801061229A patent/CN1726062A/zh active Pending
- 2003-11-17 JP JP2004552627A patent/JP2006510613A/ja not_active Ceased
- 2003-11-17 EP EP03811379A patent/EP1565239B8/en not_active Expired - Lifetime
- 2003-11-17 BR BR0316383-0A patent/BR0316383A/pt not_active IP Right Cessation
- 2003-11-17 AR ARP030104235A patent/AR042199A1/es not_active Application Discontinuation
- 2003-11-18 US US10/715,130 patent/US7087620B2/en not_active Expired - Fee Related
-
2004
- 2004-03-03 SA SA04250023A patent/SA04250023B1/ar unknown
-
2005
- 2005-05-17 IL IL168630A patent/IL168630A/en not_active IP Right Cessation
- 2005-05-19 ZA ZA200504049A patent/ZA200504049B/en unknown
- 2005-06-20 NO NO20053010A patent/NO20053010L/no not_active Application Discontinuation
- 2005-07-13 US US11/179,635 patent/US20050261300A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR101059330B1 (ko) | 2011-08-24 |
| US7087620B2 (en) | 2006-08-08 |
| US20040152716A1 (en) | 2004-08-05 |
| ATE501758T1 (de) | 2011-04-15 |
| AU2003296580B8 (en) | 2010-03-18 |
| AU2003296580A1 (en) | 2004-06-15 |
| SA04250023B1 (ar) | 2008-12-23 |
| DE60336417D1 (de) | 2011-04-28 |
| JP2006510613A (ja) | 2006-03-30 |
| WO2004045591A3 (en) | 2004-07-22 |
| TW200418468A (en) | 2004-10-01 |
| WO2004045591A2 (en) | 2004-06-03 |
| BR0316383A (pt) | 2005-10-04 |
| EP1565239B1 (en) | 2011-03-16 |
| US20050261300A1 (en) | 2005-11-24 |
| ZA200504049B (en) | 2006-07-26 |
| CA2506083A1 (en) | 2004-06-03 |
| CN1726062A (zh) | 2006-01-25 |
| NO20053010L (no) | 2005-06-20 |
| MXPA05005344A (es) | 2005-08-03 |
| RU2005119280A (ru) | 2006-03-20 |
| EP1565239A2 (en) | 2005-08-24 |
| AR042199A1 (es) | 2005-06-15 |
| IL168630A (en) | 2013-08-29 |
| AU2003296580B2 (en) | 2010-02-18 |
| KR20050116125A (ko) | 2005-12-09 |
| EP1565239B8 (en) | 2011-06-22 |
| RU2358732C2 (ru) | 2009-06-20 |
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