NO20053010L - Flytende farmasoytiske preparater inneholdende 3,7- diazabisyklo [3,3,1] nonaner for behandling av anti- arytmiske hendelser. - Google Patents
Flytende farmasoytiske preparater inneholdende 3,7- diazabisyklo [3,3,1] nonaner for behandling av anti- arytmiske hendelser.Info
- Publication number
- NO20053010L NO20053010L NO20053010A NO20053010A NO20053010L NO 20053010 L NO20053010 L NO 20053010L NO 20053010 A NO20053010 A NO 20053010A NO 20053010 A NO20053010 A NO 20053010A NO 20053010 L NO20053010 L NO 20053010L
- Authority
- NO
- Norway
- Prior art keywords
- antiarrhythmic
- diazabicyclo
- events
- treatment
- liquid pharmaceutical
- Prior art date
Links
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 3
- 238000011282 treatment Methods 0.000 title abstract 3
- PTPQJKANBKHDPM-UHFFFAOYSA-N 3,7-diazabicyclo[3.3.1]nonane Chemical class C1NCC2CNCC1C2 PTPQJKANBKHDPM-UHFFFAOYSA-N 0.000 title abstract 2
- 230000003288 anthiarrhythmic effect Effects 0.000 title abstract 2
- 239000003416 antiarrhythmic agent Substances 0.000 title abstract 2
- 239000007788 liquid Substances 0.000 title abstract 2
- 206010003658 Atrial Fibrillation Diseases 0.000 abstract 2
- 206010033557 Palpitations Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- BKIMMITUMNQMOS-UHFFFAOYSA-N nonane Chemical class CCCCCCCCC BKIMMITUMNQMOS-UHFFFAOYSA-N 0.000 abstract 1
- 229940127557 pharmaceutical product Drugs 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 230000033764 rhythmic process Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- CTIRHWCPXYGDGF-HDICACEKSA-N tedisamil Chemical compound [H][C@]12CN(CC3CC3)C[C@]([H])(CN(CC3CC3)C1)C21CCCC1 CTIRHWCPXYGDGF-HDICACEKSA-N 0.000 abstract 1
- 229960002926 tedisamil Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4747—Quinolines; Isoquinolines spiro-condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
Abstract
Den foreliggende oppfinnelse vedrører anvendelsen av 3,7-diazabisyklo[3,3,1]nonanforbindelser, fortrinnsvis av 9,9-alkylen-3,7diazabisyklo[3,3,1]nonan-forbindelser, og mest foretrukket anvendelsen av tedisamil, og de fysiologisk akseptable syreaddisjonssaltene og/eller solvatene derav, i form av et flytende farmasøytisk preparat for behandling og/eller profylakse av anti-arytmiske hendelser hos menneskepasienter, fortrinnsvis ved omstilling av nylig oppstart av atrieflimmer (Afib) eller hjertebank til normal sinusrytme (NSR) hos menneskepasienter. Dessuten vedrører oppfinnelsen en fremgangsmåte for behandlinger, og farmasøytiske produkter.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42679502P | 2002-11-18 | 2002-11-18 | |
| PCT/EP2003/012844 WO2004045591A2 (en) | 2002-11-18 | 2003-11-17 | Liquid pharmaceutical formulations containing 3,7-diazabicyclo`3,3,1! nonanes for treating anti-arrhythmic events |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20053010L true NO20053010L (no) | 2005-06-20 |
Family
ID=32326429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20053010A NO20053010L (no) | 2002-11-18 | 2005-06-20 | Flytende farmasoytiske preparater inneholdende 3,7- diazabisyklo [3,3,1] nonaner for behandling av anti- arytmiske hendelser. |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US7087620B2 (no) |
| EP (1) | EP1565239B8 (no) |
| JP (1) | JP2006510613A (no) |
| KR (1) | KR101059330B1 (no) |
| CN (1) | CN1726062A (no) |
| AR (1) | AR042199A1 (no) |
| AT (1) | ATE501758T1 (no) |
| AU (1) | AU2003296580B8 (no) |
| BR (1) | BR0316383A (no) |
| CA (1) | CA2506083A1 (no) |
| DE (1) | DE60336417D1 (no) |
| IL (1) | IL168630A (no) |
| MX (1) | MXPA05005344A (no) |
| NO (1) | NO20053010L (no) |
| RU (1) | RU2358732C2 (no) |
| SA (1) | SA04250023B1 (no) |
| TW (1) | TW200418468A (no) |
| UA (1) | UA85546C2 (no) |
| WO (1) | WO2004045591A2 (no) |
| ZA (1) | ZA200504049B (no) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200418468A (en) * | 2002-11-18 | 2004-10-01 | Solvay Pharm Gmbh | Liquid pharmaceutical formulations containing 3,7-diazabicyclo[3,3,1]nonane compounds and method of treatments relating to anti-arrhytmic events |
| US20050054667A1 (en) * | 2003-07-21 | 2005-03-10 | Solvay Pharmaceuticals Gmbh | Method of treating or inhibiting anti-arrhythmic events in male human patients |
| AU2004260624A1 (en) * | 2003-07-21 | 2005-02-10 | Solvay Pharmaceuticals Gmbh | Use of 3,7-diazabicyclo`3, 3,1 !nonane compounds for the treatment and/or prophylaxis of anti-arrhythmic events in male human patients |
| JPWO2007023775A1 (ja) * | 2005-08-23 | 2009-02-26 | アステラス製薬株式会社 | 心房細動治療剤 |
| EP2149370A1 (en) * | 2008-07-31 | 2010-02-03 | Neuroscienze Pharmaness S.C. A R.L. | Diazabicyclic compounds and microemulsions thereof |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3361244D1 (de) * | 1982-01-29 | 1986-01-02 | Ici Plc | Alkanolamine derivatives |
| DE3234697A1 (de) * | 1982-09-18 | 1984-03-22 | Kali-Chemie Pharma Gmbh, 3000 Hannover | Neue diazabicyclo-(3,3,1)-nonane |
| PT88381B (pt) * | 1987-09-09 | 1995-07-06 | Kali Chemie Pharma Gmbh | Processo para a preparacao de novos compostos 3,7-diazabiciclo{3,3,1} nonano, e de composicoes farmaceuticas que contem estes compostos |
| DE4019080A1 (de) * | 1990-06-15 | 1991-12-19 | Kali Chemie Pharma Gmbh | Neue 3,7-diazabicycolo (3,3,1)nonan-verbindungen enthaltende arzneimittel |
| DE4139763A1 (de) * | 1991-12-03 | 1993-06-09 | Kali-Chemie Pharma Gmbh, 3000 Hannover, De | Kristalline fumarsaure salze von 9,9-alkylen-3,7-diazabicyclononan-verbindungen und diese verbindungen enthaltende arzneimittel |
| DE4402931A1 (de) * | 1994-02-01 | 1995-08-03 | Kali Chemie Pharma Gmbh | Neue 3-Phenylsulfonyl-3,7-diazabicyclo[3,3,1] nonan-Verbindungen enthaltende Arzneimittel |
| DE4402933A1 (de) * | 1994-02-01 | 1995-08-03 | Kali Chemie Pharma Gmbh | Neue 3-Benzoyl-3,7-diazabicyclo[3,3,1] nonan-Verbindungen enthaltende Arzneimittel |
| US5576349A (en) * | 1995-11-30 | 1996-11-19 | The General Hospital Corporation | Retionoic acid treatment of cardiac arrhythmia |
| US6026817A (en) * | 1996-11-14 | 2000-02-22 | Clemens; Anton H. | Method of treating the syndrome of coronary heart disease risk factors in humans |
| SE9704709D0 (sv) * | 1997-12-17 | 1997-12-17 | Astra Ab | Pharmaceutically active compounds |
| US6790463B2 (en) * | 2001-03-30 | 2004-09-14 | Robert F. Hofmann | Uses of targeted oxidative therapeutic formulation in arteriosclerosis |
| DE10131217A1 (de) * | 2001-06-28 | 2003-01-09 | Solvay Pharm Gmbh | 3-Phenyl-3,7-diazabicyclo 3,3,1 nonan-Verbindungen sowie Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
| TW200418468A (en) * | 2002-11-18 | 2004-10-01 | Solvay Pharm Gmbh | Liquid pharmaceutical formulations containing 3,7-diazabicyclo[3,3,1]nonane compounds and method of treatments relating to anti-arrhytmic events |
-
2003
- 2003-11-13 TW TW092131744A patent/TW200418468A/zh unknown
- 2003-11-17 AU AU2003296580A patent/AU2003296580B8/en not_active Ceased
- 2003-11-17 KR KR1020057008973A patent/KR101059330B1/ko not_active Expired - Fee Related
- 2003-11-17 AT AT03811379T patent/ATE501758T1/de not_active IP Right Cessation
- 2003-11-17 UA UAA200505967A patent/UA85546C2/ru unknown
- 2003-11-17 DE DE60336417T patent/DE60336417D1/de not_active Expired - Lifetime
- 2003-11-17 CA CA002506083A patent/CA2506083A1/en not_active Abandoned
- 2003-11-17 MX MXPA05005344A patent/MXPA05005344A/es unknown
- 2003-11-17 WO PCT/EP2003/012844 patent/WO2004045591A2/en not_active Ceased
- 2003-11-17 RU RU2005119280/15A patent/RU2358732C2/ru not_active IP Right Cessation
- 2003-11-17 CN CNA2003801061229A patent/CN1726062A/zh active Pending
- 2003-11-17 JP JP2004552627A patent/JP2006510613A/ja not_active Ceased
- 2003-11-17 EP EP03811379A patent/EP1565239B8/en not_active Expired - Lifetime
- 2003-11-17 BR BR0316383-0A patent/BR0316383A/pt not_active IP Right Cessation
- 2003-11-17 AR ARP030104235A patent/AR042199A1/es not_active Application Discontinuation
- 2003-11-18 US US10/715,130 patent/US7087620B2/en not_active Expired - Fee Related
-
2004
- 2004-03-03 SA SA04250023A patent/SA04250023B1/ar unknown
-
2005
- 2005-05-17 IL IL168630A patent/IL168630A/en not_active IP Right Cessation
- 2005-05-19 ZA ZA200504049A patent/ZA200504049B/en unknown
- 2005-06-20 NO NO20053010A patent/NO20053010L/no not_active Application Discontinuation
- 2005-07-13 US US11/179,635 patent/US20050261300A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR101059330B1 (ko) | 2011-08-24 |
| US7087620B2 (en) | 2006-08-08 |
| US20040152716A1 (en) | 2004-08-05 |
| ATE501758T1 (de) | 2011-04-15 |
| AU2003296580B8 (en) | 2010-03-18 |
| AU2003296580A1 (en) | 2004-06-15 |
| SA04250023B1 (ar) | 2008-12-23 |
| DE60336417D1 (de) | 2011-04-28 |
| JP2006510613A (ja) | 2006-03-30 |
| WO2004045591A3 (en) | 2004-07-22 |
| TW200418468A (en) | 2004-10-01 |
| WO2004045591A2 (en) | 2004-06-03 |
| BR0316383A (pt) | 2005-10-04 |
| EP1565239B1 (en) | 2011-03-16 |
| US20050261300A1 (en) | 2005-11-24 |
| ZA200504049B (en) | 2006-07-26 |
| CA2506083A1 (en) | 2004-06-03 |
| CN1726062A (zh) | 2006-01-25 |
| UA85546C2 (en) | 2009-02-10 |
| MXPA05005344A (es) | 2005-08-03 |
| RU2005119280A (ru) | 2006-03-20 |
| EP1565239A2 (en) | 2005-08-24 |
| AR042199A1 (es) | 2005-06-15 |
| IL168630A (en) | 2013-08-29 |
| AU2003296580B2 (en) | 2010-02-18 |
| KR20050116125A (ko) | 2005-12-09 |
| EP1565239B8 (en) | 2011-06-22 |
| RU2358732C2 (ru) | 2009-06-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |