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SI3010503T1 - Novi biciklični inhibitorji bromodomene - Google Patents

Novi biciklični inhibitorji bromodomene

Info

Publication number
SI3010503T1
SI3010503T1 SI201431582T SI201431582T SI3010503T1 SI 3010503 T1 SI3010503 T1 SI 3010503T1 SI 201431582 T SI201431582 T SI 201431582T SI 201431582 T SI201431582 T SI 201431582T SI 3010503 T1 SI3010503 T1 SI 3010503T1
Authority
SI
Slovenia
Prior art keywords
bromodomain inhibitors
novel bicyclic
bicyclic bromodomain
novel
inhibitors
Prior art date
Application number
SI201431582T
Other languages
English (en)
Inventor
Bryan Cordell Duffy
Shuang Liu
John Frederick Quinn
Ruifang Wang
May Xiaowu Jiang
Gregory Scott Martin
Gregory Steven Wagner
Peter Ronald Young
Original Assignee
Zenith Epigenetics Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zenith Epigenetics Ltd. filed Critical Zenith Epigenetics Ltd.
Publication of SI3010503T1 publication Critical patent/SI3010503T1/sl

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
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