SE8500107D0 - Neue 8alfa-acylaminoergoline - Google Patents

Neue 8alfa-acylaminoergoline

Info

Publication number: SE8500107D0
Authority: SE; Sweden
Prior art keywords: 8alfa; acylaminoergoline; new; hydrogen; 5alkenyl
Prior art date: 1984-01-12

Application number

SE8500107A

Other languages

English (en)

Other versions

SE460420B (sv

SE8500107L (sv

Inventor

W Haefliger

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-01-12

Filing date

1985-01-10

Publication date

1985-01-10

1985-01-10 Application filed by Sandoz Ag filed Critical Sandoz Ag

1985-01-10 Publication of SE8500107D0 publication Critical patent/SE8500107D0/sv

1985-07-13 Publication of SE8500107L publication Critical patent/SE8500107L/sv

1989-10-09 Publication of SE460420B publication Critical patent/SE460420B/sv

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
- C07D457/06—Lysergic acid amides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
- C07D457/12—Nitrogen atoms

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Anesthesiology (AREA)
Hospice & Palliative Care (AREA)
Otolaryngology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

SE8500107A 1984-01-12 1985-01-10 8-alfa-acylaminoergoliner, foerfarande foer framstaellning av dessa och ett farmaceutiskt preparat SE460420B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE3400853		1984-01-12

Publications (3)

Publication Number	Publication Date
SE8500107D0 true SE8500107D0 (sv)	1985-01-10
SE8500107L SE8500107L (sv)	1985-07-13
SE460420B SE460420B (sv)	1989-10-09

Family

ID=6224786

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE8500107A SE460420B (sv)	1984-01-12	1985-01-10	8-alfa-acylaminoergoliner, foerfarande foer framstaellning av dessa och ett farmaceutiskt preparat

Country Status (28)

Country	Link
US (2)	US4950672A (sv)
JP (1)	JPH0655739B2 (sv)
AT (1)	AT391317B (sv)
AU (3)	AU583489B2 (sv)
BE (1)	BE901456A (sv)
CA (1)	CA1245640A (sv)
CH (1)	CH664568A5 (sv)
CY (1)	CY1542A (sv)
DE (1)	DE3500251C2 (sv)
DK (1)	DK169891B1 (sv)
ES (1)	ES8605514A1 (sv)
FI (1)	FI82466C (sv)
FR (1)	FR2560196B1 (sv)
GB (1)	GB2152507B (sv)
GR (1)	GR850065B (sv)
HK (1)	HK48590A (sv)
HU (1)	HU197569B (sv)
IE (1)	IE58228B1 (sv)
IL (1)	IL74043A (sv)
IT (1)	IT1214648B (sv)
LU (1)	LU85725A1 (sv)
NL (1)	NL193541C (sv)
NZ (1)	NZ210818A (sv)
PH (1)	PH23286A (sv)
PT (1)	PT79818B (sv)
SE (1)	SE460420B (sv)
SG (1)	SG32390G (sv)
ZA (1)	ZA85276B (sv)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH664568A5 (de) *	1984-01-12	1988-03-15	Sandoz Ag	8-alpha-acylaminoergoline.
EP0160842B1 (de) *	1984-04-09	1994-06-22	Schering Aktiengesellschaft	2-substituierte Ergolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
NL8700046A (nl) *	1986-01-24	1987-08-17	Sandoz Ag	8 alfa-acylaminoergolinen, werkwijzen voor hun bereiding en farmaceutische preparaten die ze bevatten.
US4981859A (en) *	1987-06-15	1991-01-01		Cycloalkylamides of (8 beta )-1-alkyl-6-(substituted)ergolines
US4931447A (en) *	1987-06-15	1990-06-05	Eli Lilly And Company	Cycloalkylamides of (8β)-1-alkyl-6-(substituted) ergolines
IT1219652B (it) *	1987-06-23	1990-05-24	Sandoz Ag	8-acilamminoergolina,la sua preparazione e il suo impiego come medicamneto
DE3820159A1 (de) *	1987-06-23	1989-01-05	Sandoz Ag	8(alpha)-acylaminoergolin, seine herstellung und dieses enthaltende arzneimittel
DK338789A (da) *	1988-07-15	1990-01-16	Schering Ag	2-substituerede ergolinylurinstofderivater og fremgangsmaade til fremstilling deraf, deres anvendelse som laegemidler samt mellemprodukter til fremstilling deraf
GB8824744D0 (en) *	1988-10-21	1988-11-30	Erba Carlo Spa	Antiemesis ergoline derivatives
DE3915950A1 (de) *	1989-05-12	1990-11-15	Schering Ag	8(alpha)-acylamino-ergoline, ihre herstellung und verwendung als arzneimittel
CA2974117A1 (en)	2015-01-20	2016-07-28	Xoc Pharmaceuticals, Inc.	Ergoline compounds and uses thereof
US9676776B2 (en) *	2015-01-20	2017-06-13	Xoc Pharmaceuticals, Inc.	Isoergoline compounds and uses thereof
MX2019014272A (es)	2017-06-01	2020-12-11	Xoc Pharmaceuticals Inc	Compuestos policiclicos y usos de los mismos.

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3218323A (en) *		1965-11-16		Esters of i,g-dimethyl-b-ergolenyl carbamic acid
US2864822A (en) *	1956-10-22	1958-12-16	Lilly Co Eli	9-amino-7-methyl-belta10-ergolene and derivatives thereof
CH622519A5 (en) *	1974-07-05	1981-04-15	Hoechst Ag	Process for the preparation of hydroxyalkylxanthines
US4348392A (en) *	1974-07-19	1982-09-07	Sandoz Ltd.	8α-Substituted ergoline-I derivatives
GB1517971A (en) *	1974-07-19	1978-07-19	Sandoz Ltd	8alpha-substituted ergoline i derivatives
US3922347A (en) *	1974-12-19	1975-11-25	Lilly Co Eli	Method of inhibiting prolactin secretion with 8-acylaminoergolenes
CH615929A5 (en) *	1975-06-02	1980-02-29	Sandoz Ag	Process for the preparation of novel ergoline compounds
DE2656344A1 (de) *	1975-12-23	1977-07-07	Sandoz Ag	Ergolinderivate, ihre verwendung und herstellung
CH622518A5 (en) *	1976-12-14	1981-04-15	Sandoz Ag	Process for the preparation of novel ergoline compounds
CH644606A5 (de) *	1980-09-23	1984-08-15	Sandoz Ag	Verfahren zur isomerisierung von 9,10-dihydrolysergsaeurederivaten.
DE3151912A1 (de) *	1981-12-23	1983-06-30	Schering Ag, 1000 Berlin Und 4619 Bergkamen	Neue ergolin-aminoderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
CH664568A5 (de) *	1984-01-12	1988-03-15	Sandoz Ag	8-alpha-acylaminoergoline.
CH666035A5 (de) *	1984-12-24	1988-06-30	Sandoz Ag	8-alpha-acylaminoergolene.
IT1219652B (it) *	1987-06-23	1990-05-24	Sandoz Ag	8-acilamminoergolina,la sua preparazione e il suo impiego come medicamneto

1985
- 1985-01-03 CH CH16/85A patent/CH664568A5/de not_active IP Right Cessation
- 1985-01-03 NL NL8500008A patent/NL193541C/nl not_active IP Right Cessation
- 1985-01-03 HU HU8524A patent/HU197569B/hu unknown
- 1985-01-05 DE DE3500251A patent/DE3500251C2/de not_active Expired - Fee Related
- 1985-01-07 FR FR8500217A patent/FR2560196B1/fr not_active Expired
- 1985-01-08 GB GB08500454A patent/GB2152507B/en not_active Expired
- 1985-01-08 BE BE1/11168A patent/BE901456A/fr not_active IP Right Cessation
- 1985-01-10 IE IE6485A patent/IE58228B1/en not_active IP Right Cessation
- 1985-01-10 GR GR850065A patent/GR850065B/el unknown
- 1985-01-10 DK DK012685A patent/DK169891B1/da active
- 1985-01-10 CA CA000471859A patent/CA1245640A/en not_active Expired
- 1985-01-10 PT PT79818A patent/PT79818B/pt not_active IP Right Cessation
- 1985-01-10 LU LU85725A patent/LU85725A1/fr unknown
- 1985-01-10 SE SE8500107A patent/SE460420B/sv not_active IP Right Cessation
- 1985-01-11 JP JP60003913A patent/JPH0655739B2/ja not_active Expired - Lifetime
- 1985-01-11 AT AT0005985A patent/AT391317B/de not_active IP Right Cessation
- 1985-01-11 IT IT8547538A patent/IT1214648B/it active
- 1985-01-11 AU AU37609/85A patent/AU583489B2/en not_active Ceased
- 1985-01-11 ES ES539511A patent/ES8605514A1/es not_active Expired
- 1985-01-11 IL IL74043A patent/IL74043A/xx not_active IP Right Cessation
- 1985-01-11 NZ NZ210818A patent/NZ210818A/xx unknown
- 1985-01-11 FI FI850130A patent/FI82466C/sv not_active IP Right Cessation
- 1985-01-11 ZA ZA85276A patent/ZA85276B/xx unknown
- 1985-01-14 PH PH31714A patent/PH23286A/en unknown
1988
- 1988-11-11 AU AU25066/88A patent/AU609539B2/en not_active Ceased
- 1988-11-11 AU AU25067/88A patent/AU618290B2/en not_active Ceased
1989
- 1989-02-27 US US07/316,363 patent/US4950672A/en not_active Expired - Fee Related
1990
- 1990-05-02 SG SG32390A patent/SG32390G/en unknown
- 1990-06-21 HK HK485/90A patent/HK48590A/xx not_active IP Right Cessation
- 1990-07-02 US US07/547,899 patent/US5077298A/en not_active Expired - Lifetime
1991
- 1991-03-22 CY CY1542A patent/CY1542A/en unknown

Also Published As

Publication number	Publication date
FI850130L (fi)	1985-07-13
US4950672A (en)	1990-08-21
AU3760985A (en)	1985-07-18
IL74043A0 (en)	1985-04-30
GR850065B (sv)	1985-05-03
FI82466B (fi)	1990-11-30
PT79818A (en)	1985-02-01
IL74043A (en)	1988-10-31
IE850064L (en)	1985-07-12
SE460420B (sv)	1989-10-09
AU2506688A (en)	1989-02-23
GB2152507A (en)	1985-08-07
DE3500251C2 (de)	1995-01-26
AU2506788A (en)	1989-03-02
NL193541B (nl)	1999-09-01
CA1245640A (en)	1988-11-29
JPS60174783A (ja)	1985-09-09
HU197569B (en)	1989-04-28
NL8500008A (nl)	1985-08-01
IE58228B1 (en)	1993-08-11
DK12685A (da)	1985-07-13
ES8605514A1 (es)	1986-03-16
HK48590A (en)	1990-06-29
AT391317B (de)	1990-09-25
FI850130A0 (fi)	1985-01-11
FR2560196A1 (fr)	1985-08-30
ATA5985A (de)	1990-03-15
HUT37148A (en)	1985-11-28
LU85725A1 (fr)	1985-10-22
DE3500251A1 (de)	1985-07-18
ZA85276B (en)	1986-08-27
US5077298A (en)	1991-12-31
AU618290B2 (en)	1991-12-19
NZ210818A (en)	1989-02-24
CY1542A (en)	1991-03-22
GB2152507B (en)	1987-07-15
JPH0655739B2 (ja)	1994-07-27
IT1214648B (it)	1990-01-18
PH23286A (en)	1989-06-30
DK12685D0 (da)	1985-01-10
SE8500107L (sv)	1985-07-13
GB8500454D0 (en)	1985-02-13
FI82466C (sv)	1991-03-11
PT79818B (en)	1987-01-07
ES539511A0 (es)	1986-03-16
BE901456A (fr)	1985-07-08
FR2560196B1 (fr)	1986-07-18
IT8547538A0 (it)	1985-01-11
DK169891B1 (da)	1995-03-27
NL193541C (nl)	2000-01-04
AU583489B2 (en)	1989-05-04
SG32390G (en)	1990-08-03
CH664568A5 (de)	1988-03-15
AU609539B2 (en)	1991-05-02

Publication	Publication Date	Title
ATE32077T1 (de)	1988-02-15	7-amino-azolo(1,5-a>-pyrimidine und diese enthaltende fungizide.
MX9204327A (es)	1994-07-29	Beta-lactamas substituidas compuestos utiles como agentes hipocolesteromicos y procedimientos para preparar los mismos.
DK0563345T3 (da)	2002-10-14	Nye 4-arylpiperaziner og 4-arylpiperidiner
ATE305923T1 (de)	2005-10-15	Arylthioverbindungen als antibakterielle und antivirale mittel
SE7907121L (sv)	1981-02-28	Ftalimidinderivat
SE8500107D0 (sv)	1985-01-10	Neue 8alfa-acylaminoergoline
CS621987A2 (en)	1990-06-13	Coating composition
DK163287D0 (da)	1987-03-31	1,4-diazepiner og farmaceutiske midler med indhold af saadanne forbindelser
FI863836A0 (fi)	1986-09-23	Kinolinderivat.
FI942457A0 (sv)	1994-05-26	Framställning av substituerade piperidiner
SE8503415D0 (sv)	1985-07-09	Novel isoindolinyl-alkyl-piperazines
ES2104174T3 (es)	1997-10-01	Derivados de bencilamino, bencilamido y bencilimido ciclicos utilizados como agentes antipsicoticos.
SE8506125L (sv)	1986-06-25	8alfa-acylaminoergoliner, deras framstellning och farmaceutiska kopositioner innehallande dessa
DK0736009T3 (da)	2002-10-07	N-oxider af 4-arylpiperaziner og 4-arylpiperidiner som antipsykotiske medikamenter
NO177461C (no)	1995-09-20	Trijodbenzenforbindelser og kontrastmidler inneholdende disse
ES517874A0 (es)	1983-12-01	Procedimiento de preparacion de derivados de diaza-3,7a-cicloherta-(j,k)-fluorenos.
DE59405727D1 (de)	1998-05-20	Thiocarbamoylverbindungen als mikrobizide
DE3464602D1 (en)	1987-08-13	4-alkylimidazole derivatives, their preparation and their application
DK428087A (da)	1987-08-17	Dihydropyridin-5-phosphonsyre-cyclopropylenester
SE8700566L (sv)	1987-08-14	Tetracykliska kinazolinoner
DK506885A (da)	1986-05-06	3-amino-2,3-dihydro-1-benzoxepin-forbindelser og farmaceutiske praeparater indeholdende disse
DE3565265D1 (de)	1988-11-03	Benzoyl ureas

Legal Events

Date	Code	Title	Description
1995-01-31	NAL	Patent in force	Ref document number: 8500107-1 Format of ref document f/p: F
2000-09-11	NUG	Patent has lapsed	Ref document number: 8500107-1 Format of ref document f/p: F

Date

Code

Title

Description

1995-01-31

NAL

Patent in force

Ref document number: 8500107-1

Format of ref document f/p: F

2000-09-11

NUG

Patent has lapsed