DK428087A - Dihydropyridin-5-phosphonsyre-cyclopropylenester - Google Patents
Dihydropyridin-5-phosphonsyre-cyclopropylenesterInfo
- Publication number
- DK428087A DK428087A DK428087A DK428087A DK428087A DK 428087 A DK428087 A DK 428087A DK 428087 A DK428087 A DK 428087A DK 428087 A DK428087 A DK 428087A DK 428087 A DK428087 A DK 428087A
- Authority
- DK
- Denmark
- Prior art keywords
- denotes
- image
- chlorine
- denote
- cyclopropylenester
- Prior art date
Links
- 229910052801 chlorine Inorganic materials 0.000 abstract 4
- 239000000460 chlorine Substances 0.000 abstract 4
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000006274 (C1-C3)alkoxy group Chemical group 0.000 abstract 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical group FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 125000004786 difluoromethoxy group Chemical group [H]C(F)(F)O* 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- JVJQPDTXIALXOG-UHFFFAOYSA-N nitryl fluoride Chemical compound [O-][N+](F)=O JVJQPDTXIALXOG-UHFFFAOYSA-N 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
- C07F9/657163—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom
- C07F9/657181—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom the ring phosphorus atom and, at least, one ring oxygen atom being part of a (thio)phosphonic acid derivative
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61011255A JPH0655751B2 (ja) | 1986-01-22 | 1986-01-22 | ジヒドロピリジンホスホン酸環状エステル |
| JP1125586 | 1986-01-22 | ||
| JP1275586 | 1986-01-23 | ||
| JP1275586 | 1986-01-23 | ||
| US06/851,158 US4885284A (en) | 1986-01-22 | 1986-04-14 | Dihydropyridine-5-phosphonic acid cyclic propylene ester |
| US85115886 | 1986-04-14 | ||
| JP28015986 | 1986-11-25 | ||
| JP28015986 | 1986-11-25 | ||
| JP8700032 | 1987-01-20 | ||
| PCT/JP1987/000032 WO1987004439A1 (en) | 1986-01-22 | 1987-01-20 | Dihydropyridine-5-phosphonic acid cyclic propylene ester |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK428087D0 DK428087D0 (da) | 1987-08-17 |
| DK428087A true DK428087A (da) | 1987-08-17 |
| DK168821B1 DK168821B1 (da) | 1994-06-20 |
Family
ID=27455571
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK428087A DK168821B1 (da) | 1986-01-22 | 1987-08-17 | Dihydropyridin-5-phosphonsyre-cyclopropylenester, fremgangsmåde til fremstilling heraf samt sammensætning omfattende samme |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0230944B1 (da) |
| CN (1) | CN1016063B (da) |
| AR (1) | AR248142A1 (da) |
| BG (1) | BG60236B1 (da) |
| DE (1) | DE3761662D1 (da) |
| DK (1) | DK168821B1 (da) |
| FI (1) | FI85491C (da) |
| GR (2) | GR3000478T3 (da) |
| HU (1) | HU196605B (da) |
| IL (1) | IL81315A (da) |
| WO (1) | WO1987004439A1 (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2528706B2 (ja) * | 1988-05-30 | 1996-08-28 | ゼリア新薬工業株式会社 | ジヒドロピリジン化合物の製剤組成物 |
| EP0353692B1 (en) * | 1988-08-02 | 1995-10-04 | Nissan Chemical Industries Ltd. | Drug effect-enhancing agent for antitumor drug |
| JP2850376B2 (ja) * | 1988-08-02 | 1999-01-27 | 日産化学工業株式会社 | 抗癌剤薬効増強剤 |
| PT893999E (pt) * | 1996-03-18 | 2002-12-31 | Nissan Chemical Ind Ltd | Processo para a producao para a producao de preparacoes de cloridrato de efonidipina |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59161392A (ja) | 1983-03-04 | 1984-09-12 | Nippon Shinyaku Co Ltd | ジヒドロピリジン誘導体及びその製法 |
| DE3477669D1 (en) | 1983-09-26 | 1989-05-18 | Nissan Chemical Ind Ltd | Dihydropyridine-5-phosphonic acid cyclic ester |
| EP0141221A1 (en) | 1983-09-26 | 1985-05-15 | Nissan Chemical Industries Ltd. | 1,4-Dihydropyridine-5-phosphonic acid ester |
| JPS6069089A (ja) | 1983-09-26 | 1985-04-19 | Nissan Chem Ind Ltd | ジヒドロピリジン−５−ホスホネ−ト誘導体およびその製造法 |
| JPS60248693A (ja) | 1984-04-19 | 1985-12-09 | Nippon Shinyaku Co Ltd | ピリジン誘導体及び製法 |
-
1987
- 1987-01-14 CN CN87100286.8A patent/CN1016063B/zh not_active Expired
- 1987-01-19 DE DE8787100602T patent/DE3761662D1/de not_active Expired - Lifetime
- 1987-01-19 EP EP87100602A patent/EP0230944B1/en not_active Expired
- 1987-01-20 WO PCT/JP1987/000032 patent/WO1987004439A1/en not_active Ceased
- 1987-01-20 HU HU87768A patent/HU196605B/hu not_active IP Right Cessation
- 1987-01-20 IL IL81315A patent/IL81315A/xx not_active IP Right Cessation
- 1987-01-21 AR AR87306539A patent/AR248142A1/es active
- 1987-08-03 BG BG080825A patent/BG60236B1/bg unknown
- 1987-08-12 FI FI873503A patent/FI85491C/fi not_active IP Right Cessation
- 1987-08-17 DK DK428087A patent/DK168821B1/da not_active IP Right Cessation
-
1990
- 1990-05-07 GR GR90400281T patent/GR3000478T3/el unknown
- 1990-10-31 GR GR89300192T patent/GR890300192T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR248142A1 (es) | 1995-06-30 |
| DE3761662D1 (de) | 1990-03-15 |
| BG60236B2 (en) | 1994-01-24 |
| FI85491B (fi) | 1992-01-15 |
| BG60236B1 (bg) | 1994-01-24 |
| EP0230944B1 (en) | 1990-02-07 |
| EP0230944A1 (en) | 1987-08-05 |
| AU589485B2 (en) | 1989-10-12 |
| WO1987004439A1 (en) | 1987-07-30 |
| FI85491C (fi) | 1992-04-27 |
| DK428087D0 (da) | 1987-08-17 |
| IL81315A (en) | 1991-11-21 |
| FI873503A7 (fi) | 1987-08-12 |
| CN1016063B (zh) | 1992-04-01 |
| HUT44570A (en) | 1988-03-28 |
| AU6763587A (en) | 1987-07-23 |
| HU196605B (en) | 1988-12-28 |
| FI873503A0 (fi) | 1987-08-12 |
| GR3000478T3 (en) | 1991-06-28 |
| GR890300192T1 (en) | 1990-10-31 |
| DK168821B1 (da) | 1994-06-20 |
| CN87100286A (zh) | 1988-01-13 |
| IL81315A0 (en) | 1987-08-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PUP | Patent expired |