|
HU225496B1
(en)
|
1993-04-07 |
2007-01-29 |
Scios Inc |
Pharmaceutical compositions of prolonged delivery, containing peptides
|
|
US6284727B1
(en)
|
1993-04-07 |
2001-09-04 |
Scios, Inc. |
Prolonged delivery of peptides
|
|
US5424286A
(en)
|
1993-05-24 |
1995-06-13 |
Eng; John |
Exendin-3 and exendin-4 polypeptides, and pharmaceutical compositions comprising same
|
|
US5641757A
(en)
|
1994-12-21 |
1997-06-24 |
Ortho Pharmaceutical Corporation |
Stable 2-chloro-2'-deoxyadenosine formulations
|
|
ATE417622T1
(de)
|
1996-08-08 |
2009-01-15 |
Amylin Pharmaceuticals Inc |
Regulation gastrointestinaler beweglichkeit
|
|
KR100556067B1
(ko)
|
1996-08-30 |
2006-03-07 |
노보 노르디스크 에이/에스 |
지엘피 - 1 유도체
|
|
US6458924B2
(en)
|
1996-08-30 |
2002-10-01 |
Novo Nordisk A/S |
Derivatives of GLP-1 analogs
|
|
AU739020B2
(en)
|
1997-01-07 |
2001-10-04 |
Amylin Pharmaceuticals, Inc. |
Use of exendins and agonists thereof for the reduction of food intake
|
|
US7312196B2
(en)
|
1997-01-08 |
2007-12-25 |
Amylin Pharmaceuticals, Inc. |
Formulations for amylin agonist peptides
|
|
US6410511B2
(en)
|
1997-01-08 |
2002-06-25 |
Amylin Pharmaceuticals, Inc. |
Formulations for amylin agonist peptides
|
|
US6723530B1
(en)
|
1997-02-05 |
2004-04-20 |
Amylin Pharmaceuticals, Inc. |
Polynucleotides encoding proexendin, and methods and uses thereof
|
|
US7157555B1
(en)
|
1997-08-08 |
2007-01-02 |
Amylin Pharmaceuticals, Inc. |
Exendin agonist compounds
|
|
PT1019077E
(pt)
|
1997-08-08 |
2008-02-21 |
Amylin Pharmaceuticals Inc |
Novos compostos agonistas de exendina
|
|
DE69838916T2
(de)
|
1997-11-14 |
2008-12-18 |
Amylin Pharmaceuticals, Inc., San Diego |
Neuartige exendin agonisten
|
|
US7223725B1
(en)
|
1997-11-14 |
2007-05-29 |
Amylin Pharmaceuticals, Inc. |
Exendin agonist compounds
|
|
US7220721B1
(en)
|
1997-11-14 |
2007-05-22 |
Amylin Pharmaceuticals, Inc. |
Exendin agonist peptides
|
|
EP1032587B2
(en)
|
1997-11-14 |
2013-03-13 |
Amylin Pharmaceuticals, Inc. |
Novel exendin agonist compounds
|
|
JP4353544B2
(ja)
|
1998-01-09 |
2009-10-28 |
アミリン・ファーマシューティカルズ,インコーポレイテッド |
アミリン作動薬ペプチド用製剤
|
|
US6703359B1
(en)
|
1998-02-13 |
2004-03-09 |
Amylin Pharmaceuticals, Inc. |
Inotropic and diuretic effects of exendin and GLP-1
|
|
EP1056775B1
(en)
|
1998-02-27 |
2010-04-28 |
Novo Nordisk A/S |
Glp-1 derivatives of glp-1 and exendin with protracted profile of action
|
|
NZ506839A
(en)
|
1998-03-09 |
2003-05-30 |
Zealand Pharma As |
Pharmacologically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis
|
|
WO1999047160A1
(en)
|
1998-03-13 |
1999-09-23 |
Novo Nordisk A/S |
Stabilized aqueous peptide solutions
|
|
US6998387B1
(en)
|
1998-03-19 |
2006-02-14 |
Amylin Pharmaceuticals, Inc. |
Human appetite control by glucagon-like peptide receptor binding compounds
|
|
CZ294848B6
(cs)
|
1998-06-12 |
2005-03-16 |
Amylin Pharmaceuticals, Inc. |
Glukagonu podobný peptid-1 zlepšuje odpověď ß-buněk na glukózu u subjektů se zhoršenou tolerancí glukózy
|
|
DE69941510D1
(de)
|
1998-08-10 |
2009-11-19 |
Us Gov Nat Inst Health |
Differenzierung von nicht-insulin in insulin-produzierende zellen durch glp-1 und exendin-4 und dessen verwendung
|
|
CN1317967A
(zh)
|
1998-09-17 |
2001-10-17 |
伊莱利利公司 |
蛋白质制剂
|
|
US7259136B2
(en)
|
1999-04-30 |
2007-08-21 |
Amylin Pharmaceuticals, Inc. |
Compositions and methods for treating peripheral vascular disease
|
|
US6429197B1
(en)
|
1998-10-08 |
2002-08-06 |
Bionebraska, Inc. |
Metabolic intervention with GLP-1 or its biologically active analogues to improve the function of the ischemic and reperfused brain
|
|
US6284725B1
(en)
|
1998-10-08 |
2001-09-04 |
Bionebraska, Inc. |
Metabolic intervention with GLP-1 to improve the function of ischemic and reperfused tissue
|
|
DK1140148T3
(da)
|
1998-12-22 |
2006-01-30 |
Lilly Co Eli |
Lagerholdbar formulering af glucagon-agtigt peptid-1
|
|
US7399489B2
(en)
|
1999-01-14 |
2008-07-15 |
Amylin Pharmaceuticals, Inc. |
Exendin analog formulations
|
|
PT1140145E
(pt)
|
1999-01-14 |
2005-11-30 |
Amylin Pharmaceuticals Inc |
Formulacoes novas de agonistas de exendina e metodos para a sua administracao
|
|
NZ512657A
(en)
|
1999-01-14 |
2004-01-30 |
Amylin Pharmaceuticals Inc |
Glucagon suppression
|
|
US20030087820A1
(en)
|
1999-01-14 |
2003-05-08 |
Young Andrew A. |
Novel exendin agonist formulations and methods of administration thereof
|
|
US6451974B1
(en)
|
1999-03-17 |
2002-09-17 |
Novo Nordisk A/S |
Method of acylating peptides and novel acylating agents
|
|
CA2361830A1
(en)
|
1999-03-17 |
2000-09-21 |
Novo Nordisk A/S |
Method for acylating peptides and novel acylating agents
|
|
WO2000066629A1
(en)
|
1999-04-30 |
2000-11-09 |
Amylin Pharmaceuticals, Inc. |
Modified exendins and exendin agonists
|
|
US6924264B1
(en)
|
1999-04-30 |
2005-08-02 |
Amylin Pharmaceuticals, Inc. |
Modified exendins and exendin agonists
|
|
US6887470B1
(en)
|
1999-09-10 |
2005-05-03 |
Conjuchem, Inc. |
Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components
|
|
US6514500B1
(en)
|
1999-10-15 |
2003-02-04 |
Conjuchem, Inc. |
Long lasting synthetic glucagon like peptide {GLP-!}
|
|
SI1180121T1
(en)
|
1999-05-17 |
2004-04-30 |
Conjuchem, Inc. |
Long lasting insulinotropic peptides
|
|
US6849714B1
(en)
|
1999-05-17 |
2005-02-01 |
Conjuchem, Inc. |
Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components
|
|
US6482799B1
(en)
|
1999-05-25 |
2002-11-19 |
The Regents Of The University Of California |
Self-preserving multipurpose ophthalmic solutions incorporating a polypeptide antimicrobial
|
|
US6506724B1
(en)
|
1999-06-01 |
2003-01-14 |
Amylin Pharmaceuticals, Inc. |
Use of exendins and agonists thereof for the treatment of gestational diabetes mellitus
|
|
US6344180B1
(en)
|
1999-06-15 |
2002-02-05 |
Bionebraska, Inc. |
GLP-1 as a diagnostic test to determine β-cell function and the presence of the condition of IGT and type II diabetes
|
|
US6528486B1
(en)
|
1999-07-12 |
2003-03-04 |
Zealand Pharma A/S |
Peptide agonists of GLP-1 activity
|
|
US6972319B1
(en)
|
1999-09-28 |
2005-12-06 |
Bayer Pharmaceuticals Corporation |
Pituitary adenylate cyclase activating peptide (PACAP)receptor 3 (R3) agonists and their pharmacological methods of use
|
|
GB9930882D0
(en)
|
1999-12-30 |
2000-02-23 |
Nps Allelix Corp |
GLP-2 formulations
|
|
CA2396157A1
(en)
|
2000-01-10 |
2001-07-19 |
Amylin Pharmaceuticals, Inc. |
Use of exendins and agonists thereof for modulation of triglyceride levels and treatment of dyslipidemia
|
|
AU2001252201A1
(en)
|
2000-03-14 |
2001-09-24 |
Amylin Pharmaceuticals, Inc. |
Effects of glucagon-like peptide-1 (7-36) on antro-pyloro-duodenal motility
|
|
WO2001087322A2
(en)
|
2000-05-17 |
2001-11-22 |
Bionebraska, Inc. |
Peptide pharmaceutical formulations
|
|
KR100518046B1
(ko)
|
2000-05-19 |
2005-10-04 |
아밀린 파마슈티칼스, 인크. |
Glp-1을 사용한 급성 관상동맥 증후군의 치료
|
|
WO2002016309A1
(en)
|
2000-08-18 |
2002-02-28 |
Emisphere Technologies, Inc. |
Compounds and compositions for delivering active agents
|
|
US7507714B2
(en)
|
2000-09-27 |
2009-03-24 |
Bayer Corporation |
Pituitary adenylate cyclase activating peptide (PACAP) receptor 3 (R3) agonists and their pharmacological methods of use
|
|
WO2002034285A2
(en)
|
2000-10-20 |
2002-05-02 |
Coolidge Thomas R |
Treatment of hibernating myocardium and diabetic cardiomyopathy with a glp-1 peptide
|
|
BR0116024A
(pt)
|
2000-12-07 |
2005-12-13 |
Lilly Co Eli |
Proteìna de fusão heteróloga e uso da mesma
|
|
US7259233B2
(en)
|
2000-12-13 |
2007-08-21 |
Eli Lilly And Company |
Chronic treatment regimen using glucagon-like insulinotropic peptides
|
|
GB2371227A
(en)
|
2001-01-10 |
2002-07-24 |
Grandis Biotech Gmbh |
Crystallisation - resistant aqueous growth hormone formulations
|
|
US6573237B2
(en)
|
2001-03-16 |
2003-06-03 |
Eli Lilly And Company |
Protein formulations
|
|
CN1162446C
(zh)
|
2001-05-10 |
2004-08-18 |
上海华谊生物技术有限公司 |
促胰岛素分泌肽衍生物
|
|
AU2002308706A1
(en)
|
2001-06-01 |
2002-12-16 |
Eli Lilly And Company |
Glp-1 formulations with protracted time action
|
|
ATE382057T1
(de)
|
2001-06-28 |
2008-01-15 |
Novo Nordisk As |
Stabile formulierung von modifiziertem glp-1
|
|
ES2320431T3
(es)
|
2001-07-16 |
2009-05-22 |
Caprotec Bioanalytics Gmbh |
Compuestos de captura, colecciones de los mismos y metodos para analizar el proteoma y composiciones complejas.
|
|
DE60228972D1
(de)
|
2001-07-31 |
2008-10-30 |
Us Gov Health & Human Serv |
Glp 1 exendin 4 peptidanaloga und deren verwendungen
|
|
US7238663B2
(en)
|
2001-08-28 |
2007-07-03 |
Eli Lilly And Company |
Pre-mixes of GLP-1 and basal insulin
|
|
CN1571676A
(zh)
|
2001-10-19 |
2005-01-26 |
伊莱利利公司 |
Glp-1和胰岛素的双相混合物
|
|
EP2277889B1
(en)
|
2001-12-21 |
2014-07-09 |
Human Genome Sciences, Inc. |
Fusion proteins of albumin and interferon beta
|
|
CA2484556A1
(en)
|
2001-12-21 |
2003-07-24 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
|
US7105489B2
(en)
|
2002-01-22 |
2006-09-12 |
Amylin Pharmaceuticals, Inc. |
Methods and compositions for treating polycystic ovary syndrome
|
|
JP4417113B2
(ja)
|
2002-02-20 |
2010-02-17 |
エミスフェアー・テクノロジーズ・インク |
Glp−1分子の投与方法
|
|
PT1946776T
(pt)
|
2002-02-27 |
2017-03-17 |
Immunex Corp |
Composição de tnfr-fc estabilizada compreendendo arginina
|
|
WO2003077851A2
(en)
|
2002-03-11 |
2003-09-25 |
Hk Pharmaceuticals, Inc. |
Compounds and methods for analyzing the proteome
|
|
US7141240B2
(en)
|
2002-03-12 |
2006-11-28 |
Cedars-Sinai Medical Center |
Glucose-dependent insulin-secreting cells transfected with a nucleotide sequence encoding GLP-1
|
|
JP2005535569A
(ja)
|
2002-04-04 |
2005-11-24 |
ノボ・ノルデイスク・エー/エス |
Glp−1アゴニスト及び心臓血管合併症
|
|
EA200401345A1
(ru)
|
2002-04-10 |
2005-08-25 |
Эли Лилли Энд Компани |
Лечение гастропареза
|
|
US6861236B2
(en)
|
2002-05-24 |
2005-03-01 |
Applied Nanosystems B.V. |
Export and modification of (poly)peptides in the lantibiotic way
|
|
AU2003232172A1
(en)
|
2002-06-14 |
2003-12-31 |
Novo Nordisk A/S |
Combined use of a modulator of cd3 and a glp-1 compound
|
|
US20040037826A1
(en)
|
2002-06-14 |
2004-02-26 |
Michelsen Birgitte Koch |
Combined use of a modulator of CD3 and a GLP-1 compound
|
|
DE10227232A1
(de)
|
2002-06-18 |
2004-01-15 |
Aventis Pharma Deutschland Gmbh |
Saure Insulinzubereitungen mit verbesserter Stabilität
|
|
ATE432289T1
(de)
|
2002-07-04 |
2009-06-15 |
Zealand Pharma As |
Glp-1 und behandlungsmethode für diabetes
|
|
WO2004004780A1
(en)
|
2002-07-09 |
2004-01-15 |
Sandoz Ag |
Liquid formulations with high concentration of human growth hormone (hgh) comprising phenol
|
|
US20070065469A1
(en)
|
2002-07-09 |
2007-03-22 |
Michael Betz |
Liquid formulations with high concentration of human growth hormone (high) comprising glycine
|
|
US20040038865A1
(en)
|
2002-08-01 |
2004-02-26 |
Mannkind Corporation |
Cell transport compositions and uses thereof
|
|
US20080260838A1
(en)
|
2003-08-01 |
2008-10-23 |
Mannkind Corporation |
Glucagon-like peptide 1 (glp-1) pharmaceutical formulations
|
|
AU2003257156B2
(en)
|
2002-08-01 |
2007-08-30 |
Mannkind Corporation |
Cell transport compositions and uses thereof
|
|
EA016166B1
(ru)
|
2002-08-21 |
2012-02-28 |
Бёрингер Ингельхайм Фарма Гмбх & Ко. Кг |
8-[3-аминопиперидин-1-ил]ксантины, способ их получения и их применение в качестве лекарственных средств
|
|
US7407955B2
(en)
|
2002-08-21 |
2008-08-05 |
Boehringer Ingelheim Pharma Gmbh & Co., Kg |
8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
|
|
AU2003268621B2
(en)
|
2002-10-02 |
2009-01-15 |
Zealand Pharma A/S |
Stabilized exendin-4 compounds
|
|
US20050209142A1
(en)
|
2002-11-20 |
2005-09-22 |
Goran Bertilsson |
Compounds and methods for increasing neurogenesis
|
|
ATE494904T1
(de)
|
2002-11-20 |
2011-01-15 |
Neuronova Ab |
Verbindungen und verfahren zur erhöhung der neurogenese
|
|
US6969702B2
(en)
|
2002-11-20 |
2005-11-29 |
Neuronova Ab |
Compounds and methods for increasing neurogenesis
|
|
US20040209803A1
(en)
|
2002-12-19 |
2004-10-21 |
Alain Baron |
Compositions for the treatment and prevention of nephropathy
|
|
US7790681B2
(en)
|
2002-12-17 |
2010-09-07 |
Amylin Pharmaceuticals, Inc. |
Treatment of cardiac arrhythmias with GLP-1 receptor ligands
|
|
JP2006514035A
(ja)
|
2002-12-17 |
2006-04-27 |
アミリン・ファーマシューティカルズ,インコーポレイテッド |
心不整脈の予防および治療
|
|
GB0300571D0
(en)
|
2003-01-10 |
2003-02-12 |
Imp College Innovations Ltd |
Modification of feeding behaviour
|
|
WO2004089280A2
(en)
|
2003-04-08 |
2004-10-21 |
Yeda Research And Development Co. Ltd. |
Reversible pegylated drugs
|
|
WO2004089985A1
(en)
|
2003-04-11 |
2004-10-21 |
Novo Nordisk A/S |
Stable pharmaceutical compositions
|
|
ATE549028T1
(de)
|
2003-05-15 |
2012-03-15 |
Tufts College |
Stabile analoga von glp-1
|
|
US7947261B2
(en)
|
2003-05-23 |
2011-05-24 |
Nektar Therapeutics |
Conjugates formed from polymer derivatives having particular atom arrangements
|
|
HUE043911T2
(hu)
|
2003-05-23 |
2019-09-30 |
Nektar Therapeutics |
Két PEG láncot tartalmazó PEG származékok
|
|
ES2425221T3
(es)
|
2003-05-30 |
2013-10-14 |
Amylin Pharmaceuticals, Llc |
Nuevos métodos y composiciones para suministro por vía transmucosa potenciado de péptidos y proteínas
|
|
PL1633391T3
(pl)
|
2003-06-03 |
2012-03-30 |
Novo Nordisk As |
Stabilizowane farmaceutycznie kompozycje peptydowe
|
|
WO2004105781A2
(en)
|
2003-06-03 |
2004-12-09 |
Novo Nordisk A/S |
Stabilized pharmaceutical peptide compositions
|
|
ES2375056T3
(es)
|
2003-06-03 |
2012-02-24 |
Novo Nordisk A/S |
Composiciones pept�?dicas farmacéuticas estabilizadas.
|
|
KR101308912B1
(ko)
|
2003-06-03 |
2013-09-23 |
노보 노르디스크 에이/에스 |
안정화된 약학적 펩티드 조성물
|
|
US8921311B2
(en)
|
2003-08-01 |
2014-12-30 |
Mannkind Corporation |
Method for treating hyperglycemia
|
|
EP2107069B1
(en)
|
2003-08-05 |
2013-01-16 |
Novo Nordisk A/S |
Novel insulin derivatives
|
|
AU2004266757A1
(en)
|
2003-08-21 |
2005-03-03 |
Novo Nordisk A/S |
Separation of polypeptides comprising a racemized amino acid
|
|
US20060247167A1
(en)
|
2003-09-01 |
2006-11-02 |
Novo Nordisk A/S |
Stable formulations of peptides
|
|
EP1663295A2
(en)
|
2003-09-01 |
2006-06-07 |
Novo Nordisk A/S |
Stable formulations of peptides
|
|
JP2007537981A
(ja)
|
2003-09-19 |
2007-12-27 |
ノボ ノルディスク アクティーゼルスカブ |
新規の血漿タンパク質親和性タグ
|
|
EP1684793B1
(en)
|
2003-11-13 |
2011-09-21 |
Novo Nordisk A/S |
Pharmaceutical composition comprising an insulinotropic glp-1(7-37) analogue, asp(b28)-insulin, and a surfactant
|
|
US20060287221A1
(en)
|
2003-11-13 |
2006-12-21 |
Novo Nordisk A/S |
Soluble pharmaceutical compositions for parenteral administration comprising a GLP-1 peptide and an insulin peptide of short time action for treatment of diabetes and bulimia
|
|
US20050106214A1
(en)
|
2003-11-14 |
2005-05-19 |
Guohua Chen |
Excipients in drug delivery vehicles
|
|
US20050281879A1
(en)
|
2003-11-14 |
2005-12-22 |
Guohua Chen |
Excipients in drug delivery vehicles
|
|
SI3300721T2
(sl)
|
2003-11-20 |
2025-05-30 |
Novo Nordisk A/S |
Peptidne formulacije, ki vsebujejo propilen glikol in ki so optimalne za proizvodnjo in uporabo v napravah za injiciranje
|
|
EP1750752A2
(en)
|
2003-11-20 |
2007-02-14 |
Neuronova AB |
Compounds and methods for increasing neurogenesis
|
|
ATE517119T1
(de)
|
2003-12-03 |
2011-08-15 |
Novo Nordisk As |
Einzelketteninsulin
|
|
AU2004298996A1
(en)
|
2003-12-10 |
2005-06-30 |
Nektar Therapeutics Al, Corporation |
Compositions comprising two different populations of polymer-active agent conjugates
|
|
US20060210614A1
(en)
|
2003-12-26 |
2006-09-21 |
Nastech Pharmaceutical Company Inc. |
Method of treatment of a metabolic disease using intranasal administration of exendin peptide
|
|
US20050143303A1
(en)
|
2003-12-26 |
2005-06-30 |
Nastech Pharmaceutical Company Inc. |
Intranasal administration of glucose-regulating peptides
|
|
CN1938334A
(zh)
*
|
2004-01-30 |
2007-03-28 |
瓦拉塔药品公司 |
Glp-1激动剂和胃泌素化合物的联合使用
|
|
US8076288B2
(en)
|
2004-02-11 |
2011-12-13 |
Amylin Pharmaceuticals, Inc. |
Hybrid polypeptides having glucose lowering activity
|
|
EP1789440A4
(en)
|
2004-02-11 |
2008-03-12 |
Amylin Pharmaceuticals Inc |
REASONS FOR THE FAMILY OF PANCREATIC POLYPEPTIDES AND POLYPEPTIDES CONTAINING THEM
|
|
EP2233497A3
(en)
|
2004-02-11 |
2011-01-12 |
Amylin Pharmaceuticals, Inc. |
Amylin family peptides and methods for making and using them
|
|
EP2422806A3
(en)
|
2004-02-11 |
2012-06-13 |
Amylin Pharmaceuticals Inc. |
Hybrid polypeptides with selectable properties
|
|
US7399744B2
(en)
|
2004-03-04 |
2008-07-15 |
Amylin Pharmaceuticals, Inc. |
Methods for affecting body composition
|
|
US20060110423A1
(en)
|
2004-04-15 |
2006-05-25 |
Wright Steven G |
Polymer-based sustained release device
|
|
KR101040415B1
(ko)
|
2004-04-15 |
2011-06-09 |
알케르메스,인코포레이티드 |
중합체 기재 지속적 방출 방법
|
|
US7456254B2
(en)
|
2004-04-15 |
2008-11-25 |
Alkermes, Inc. |
Polymer-based sustained release device
|
|
US20090069226A1
(en)
|
2004-05-28 |
2009-03-12 |
Amylin Pharmaceuticals, Inc. |
Transmucosal delivery of peptides and proteins
|
|
WO2005117584A2
(en)
|
2004-05-28 |
2005-12-15 |
Amylin Pharmaceuticals, Inc |
Improved transmucosal delivery of peptides and proteins
|
|
EP2316446A1
(en)
|
2004-06-11 |
2011-05-04 |
Novo Nordisk A/S |
Counteracting drug-induced obesity using GLP-1 agonists
|
|
US7872095B2
(en)
|
2004-07-19 |
2011-01-18 |
Biocon Limited |
Insulin-oligomer conjugates, formulations and uses thereof
|
|
WO2006091231A2
(en)
|
2004-07-21 |
2006-08-31 |
Ambrx, Inc. |
Biosynthetic polypeptides utilizing non-naturally encoded amino acids
|
|
EA200700391A1
(ru)
|
2004-08-03 |
2007-10-26 |
Байорексис Текнолоджи, Инк. |
Комбинированное лечение с применением слитых белков трансферрина, содержащих glp-1
|
|
US20070204633A1
(en)
|
2004-08-16 |
2007-09-06 |
Whisson Maxwell E |
Apparatus and Method for Cooling of Air
|
|
PL1789434T3
(pl)
|
2004-08-31 |
2014-07-31 |
Novo Nordisk As |
Zastosowanie tris(hydroksymetylo)aminometanu do stabilizacji peptydów, polipeptydów i białek
|
|
DE102004043153B4
(de)
|
2004-09-03 |
2013-11-21 |
Philipps-Universität Marburg |
Erfindung betreffend GLP-1 und Exendin
|
|
WO2006028110A1
(ja)
|
2004-09-07 |
2006-03-16 |
Chugai Seiyaku Kabushiki Kaisha |
水溶性ヒアルロン酸修飾物の製造方法
|
|
US20080280814A1
(en)
|
2004-09-17 |
2008-11-13 |
Novo Nordisk A/S |
Pharmaceutical Compositions Containing Insulin and Insulinotropic Peptide
|
|
MX366832B
(es)
|
2004-10-01 |
2019-07-24 |
Ramscor Inc |
Composiciones de farmaco de liberacion sostenida convenientemente implantables.
|
|
JP5107713B2
(ja)
|
2004-10-07 |
2012-12-26 |
ノヴォ ノルディスク アー/エス |
遅延性のエキセンディン−4化合物
|
|
US7595294B2
(en)
|
2004-10-08 |
2009-09-29 |
Transition Therapeutics, Inc. |
Vasoactive intestinal polypeptide pharmaceuticals
|
|
US20060089325A1
(en)
|
2004-10-13 |
2006-04-27 |
Sanjay Bhanot |
Antisense modulation of PTP1B expression
|
|
US7442682B2
(en)
|
2004-10-19 |
2008-10-28 |
Nitto Denko Corporation |
Transepithelial delivery of peptides with incretin hormone activities
|
|
ES2458991T5
(en)
|
2004-11-12 |
2025-10-14 |
Novo Nordisk As |
Stable formulations of insulinoptropic peptides
|
|
US20080125361A1
(en)
|
2004-11-12 |
2008-05-29 |
Novo Nordisk A/S |
Stable Formulations Of Peptides
|
|
US20090011976A1
(en)
|
2004-11-12 |
2009-01-08 |
Novo Nordisk A/S |
Stable Formulations Of Peptides
|
|
RU2428431C2
(ru)
|
2004-12-02 |
2011-09-10 |
Домантис Лимитед |
Слитые конструкции лекарственного средства и конъюгаты
|
|
MX2007006830A
(es)
|
2004-12-13 |
2008-02-07 |
Amylin Pharmaceuticals Inc |
Porciones de la familia del polipeptido pancreatico, polipeptidos y metodos que comprenden las mismas.
|
|
EP1827501B2
(en)
|
2004-12-21 |
2013-11-20 |
Nektar Therapeutics |
Stabilized polymeric thiol reagents
|
|
ATE435235T1
(de)
|
2004-12-22 |
2009-07-15 |
Lilly Co Eli |
Formulierungen glp-1-analoger fusionsproteine
|
|
EP1838336A2
(en)
|
2004-12-24 |
2007-10-03 |
Amylin Pharmaceuticals, Inc. |
Use of glp-1 and agonists thereof to prevent cardiac myocyte apoptosis
|
|
US8716221B2
(en)
|
2005-01-14 |
2014-05-06 |
Wuxi Grandchamp Pharmaceutical Technology Co., Ltd. |
Modified exendins and uses thereof
|
|
CN100540565C
(zh)
|
2005-01-14 |
2009-09-16 |
无锡宏创医药科技有限公司 |
修饰的Exendins及其应用
|
|
WO2006082588A2
(en)
|
2005-02-07 |
2006-08-10 |
Pharmalight Inc. |
Method and device for ophthalmic administration of active pharmaceutical ingredients
|
|
CA2597649A1
(en)
|
2005-02-11 |
2006-08-17 |
Amylin Pharmaceuticals, Inc. |
Gip analog and hybrid polypeptides with selectable properties
|
|
US8263545B2
(en)
|
2005-02-11 |
2012-09-11 |
Amylin Pharmaceuticals, Inc. |
GIP analog and hybrid polypeptides with selectable properties
|
|
WO2006097535A2
(en)
|
2005-03-18 |
2006-09-21 |
Novo Nordisk A/S |
Peptide agonists of the glucagon family with secretin like activity
|
|
DK1888103T3
(da)
|
2005-04-11 |
2012-04-23 |
Amylin Pharmaceuticals Inc |
Anvendelse af glp-1, exendin og agonister deraf til forsinkelse eller forhindring af kardial remodellering
|
|
JP4979686B2
(ja)
|
2005-04-24 |
2012-07-18 |
ノボ・ノルデイスク・エー/エス |
注入デバイス
|
|
CN101180081B
(zh)
|
2005-05-25 |
2015-08-26 |
诺沃-诺迪斯克有限公司 |
稳定的多肽制剂
|
|
CN101282991A
(zh)
|
2005-05-26 |
2008-10-08 |
布里斯托尔-迈尔斯斯奎布公司 |
N-端修饰的胰高血糖素样肽-1受体调节剂
|
|
CA2609810C
(en)
|
2005-06-06 |
2012-05-22 |
Camurus Ab |
Glp-1 analogue formulations
|
|
JP2008543816A
(ja)
|
2005-06-13 |
2008-12-04 |
インペリアル イノベーションズ リミテッド |
新規化合物および該化合物が摂食行動に及ぼす効果
|
|
GB0511986D0
(en)
|
2005-06-13 |
2005-07-20 |
Imp College Innovations Ltd |
Novel compounds and their effects on feeding behaviour
|
|
MX2007016314A
(es)
|
2005-06-16 |
2008-03-10 |
Nektar Therapeutics Al Corp |
Conjugados que tienen un enlace degradable y reactivos polimericos utiles en la preparacion de tales conjugados.
|
|
WO2007019331A2
(en)
|
2005-08-04 |
2007-02-15 |
Nektar Therapeutics Al, Corporation |
Conjugates of a g-csf moiety and a polymer
|
|
CN101277722A
(zh)
|
2005-08-06 |
2008-10-01 |
王庆华 |
用于预防和治疗ⅰ型糖尿病的组合物及方法
|
|
AU2006279680B2
(en)
|
2005-08-11 |
2012-12-06 |
Amylin Pharmaceuticals, Llc |
Hybrid polypeptides with selectable properties
|
|
DK2347762T3
(da)
|
2005-08-19 |
2019-06-11 |
Amylin Pharmaceuticals Llc |
Exendin til behandling af diabetes og reduktion af kropsvægt
|
|
US7799344B2
(en)
|
2005-09-14 |
2010-09-21 |
Mannkind Corporation |
Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents
|
|
JP5072848B2
(ja)
|
2005-09-20 |
2012-11-14 |
ノバルティス アーゲー |
低血糖イベントを低減するためのdpp−iv阻害剤の使用
|
|
WO2007047834A2
(en)
|
2005-10-18 |
2007-04-26 |
Biocon Limited |
Oral peptide conjugates for metabolic diseases
|
|
US20070099820A1
(en)
|
2005-10-19 |
2007-05-03 |
Smartcells, Inc. |
Polymer-drug conjugates
|
|
WO2007056362A2
(en)
|
2005-11-07 |
2007-05-18 |
Indiana University Research And Technology Corporation |
Glucagon analogs exhibiting physiological solubility and stability
|
|
WO2007053946A1
(en)
|
2005-11-09 |
2007-05-18 |
Conjuchem Biotechnologies Inc. |
Method of treating diabetes and/or obesity with reduced nausea side effects using an insulinotropic peptide conjugated to albumin
|
|
US8293726B2
(en)
|
2005-12-02 |
2012-10-23 |
Vianova Labs, Inc. |
Treatment of cancer and other diseases
|
|
MX2008007075A
(es)
|
2005-12-02 |
2008-11-12 |
Mdrna Inc |
Formulacion farmaceutica para incrementar la permeabilidad epitelial por peptido regulador de glucosa.
|
|
WO2007067964A2
(en)
|
2005-12-08 |
2007-06-14 |
Nastech Pharmaceutical Company Inc. |
Mucosal delivery of stabilized formulations of exendin
|
|
JP5096363B2
(ja)
|
2005-12-16 |
2012-12-12 |
ネクター セラピューティックス |
Glp−1のポリマ複合体
|
|
US8841255B2
(en)
|
2005-12-20 |
2014-09-23 |
Duke University |
Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides
|
|
EP1971355B1
(en)
|
2005-12-20 |
2020-03-11 |
Duke University |
Methods and compositions for delivering active agents with enhanced pharmacological properties
|
|
US20130172274A1
(en)
|
2005-12-20 |
2013-07-04 |
Duke University |
Methods and compositions for delivering active agents with enhanced pharmacological properties
|
|
ES2397712T3
(es)
|
2006-01-18 |
2013-03-08 |
Qps, Llc |
Composiciones farmacéuticas con estabilidad reforzada
|
|
AU2007212147A1
(en)
|
2006-02-03 |
2007-08-16 |
Medimmune, Llc |
Protein formulations
|
|
US7704953B2
(en)
|
2006-02-17 |
2010-04-27 |
Mdrna, Inc. |
Phage displayed cell binding peptides
|
|
JP5412273B2
(ja)
|
2006-03-21 |
2014-02-12 |
アミリン・ファーマシューティカルズ,リミテッド・ライアビリティ・カンパニー |
ペプチド−ぺプチダーゼ阻害剤及びその使用
|
|
CA2648440A1
(en)
|
2006-04-13 |
2007-10-25 |
Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. . |
Pharmaceutical compositions of hglp-1, exendin-4 and analogs thereof
|
|
RU2409349C2
(ru)
|
2006-04-14 |
2011-01-20 |
Маннкайнд Корпорейшн |
Фармацевтические композиции, содержащие глюкагонподобный пептид(glp-1)
|
|
PE20080251A1
(es)
|
2006-05-04 |
2008-04-25 |
Boehringer Ingelheim Int |
Usos de inhibidores de dpp iv
|
|
EP2029160A2
(en)
|
2006-05-12 |
2009-03-04 |
Amylin Pharmaceuticals, Inc. |
Methods to restore glycemic control
|
|
WO2007139589A1
(en)
|
2006-05-26 |
2007-12-06 |
Bristol-Myers Squibb Company |
Sustained release glp-1 receptor modulators
|
|
EP2636680A3
(en)
|
2006-05-26 |
2013-12-11 |
Amylin Pharmaceuticals, LLC |
Composition and methods for treatment of congestive heart failure
|
|
PT2038423E
(pt)
|
2006-06-21 |
2013-03-27 |
Biocon Ltd |
Método de produção de um polipéptido biologicamente activo possuindo actividade insulinotrópica
|
|
DK2494959T3
(en)
|
2006-07-05 |
2015-02-23 |
Foamix Pharmaceuticals Ltd |
Foam Bart dicarboxylsyrebærestof and pharmaceutical compositions thereof
|
|
CA2658654A1
(en)
|
2006-07-24 |
2008-01-31 |
Biorexis Pharmaceutical Corporation |
Exendin fusion proteins
|
|
US7928186B2
(en)
|
2006-08-02 |
2011-04-19 |
Phoenix Pharmaceuticals, Inc. |
Cell permeable bioactive peptide conjugates
|
|
EP2046284A1
(en)
|
2006-08-04 |
2009-04-15 |
Nastech Pharmaceutical Company Inc. |
Compositions for intranasal delivery of human insulin and uses thereof
|
|
AU2007284759B2
(en)
|
2006-08-09 |
2010-10-28 |
Intarcia Therapeutics, Inc. |
Osmotic delivery systems and piston assemblies
|
|
US8497240B2
(en)
|
2006-08-17 |
2013-07-30 |
Amylin Pharmaceuticals, Llc |
DPP-IV resistant GIP hybrid polypeptides with selectable properties
|
|
CA2660835A1
(en)
|
2006-08-17 |
2008-02-21 |
Amylin Pharmaceuticals, Inc. |
Dpp-iv resistant gip hybrid polypeptides with selectable propperties
|
|
US20090318353A1
(en)
*
|
2006-08-25 |
2009-12-24 |
Novo Nordisk A/S |
Acylated Exendin-4 Compounds
|
|
CN102827284B
(zh)
|
2006-11-14 |
2015-07-29 |
上海仁会生物制药股份有限公司 |
带有聚乙二醇基团的Exendin或其类似物及其制剂和用途
|
|
JP2010512399A
(ja)
|
2006-12-12 |
2010-04-22 |
アミリン・ファーマシューティカルズ,インコーポレイテッド |
医薬製剤及びその調製方法
|
|
TWI428346B
(zh)
|
2006-12-13 |
2014-03-01 |
Imp Innovations Ltd |
新穎化合物及其等對進食行為影響
|
|
RU2432361C2
(ru)
|
2007-01-05 |
2011-10-27 |
КовЭкс Текнолоджиз Айэлэнд Лимитед |
Соединения агонисты рецептора глюкагоноподобного белка-1 (glp-1r)
|
|
CN101663317A
(zh)
*
|
2007-01-05 |
2010-03-03 |
CovX科技爱尔兰有限公司 |
胰高血糖素样蛋白-1受体glp-1r激动剂化合物
|
|
US20090098130A1
(en)
*
|
2007-01-05 |
2009-04-16 |
Bradshaw Curt W |
Glucagon-like protein-1 receptor (glp-1r) agonist compounds
|
|
EP2124974B1
(en)
|
2007-01-05 |
2017-03-15 |
Indiana University Research and Technology Corporation |
Glucagon analogs exhibiting enhanced solubility in physiological ph buffers
|
|
WO2008098212A2
(en)
|
2007-02-08 |
2008-08-14 |
Diobex, Inc. |
Extended release formulations of glucagon and other peptides and proteins
|
|
AU2008216265B2
(en)
|
2007-02-15 |
2014-04-03 |
Indiana University Research And Technology Corporation |
Glucagon/GLP-1 receptor co-agonists
|
|
WO2008130066A1
(en)
|
2007-04-20 |
2008-10-30 |
Kang Choon Lee |
Mono modified exendin with polyethylene glycol or its derivatives and uses thereof
|
|
CN101715340A
(zh)
|
2007-04-23 |
2010-05-26 |
精达制药公司 |
促胰岛素释放肽的混悬制剂及其应用
|
|
US8236760B2
(en)
|
2007-04-27 |
2012-08-07 |
Cedars-Sinsai Medical Center |
Use of GLP-1 receptor agonists for the treatment of short bowel syndrome
|
|
US7829664B2
(en)
|
2007-06-01 |
2010-11-09 |
Boehringer Ingelheim International Gmbh |
Modified nucleotide sequence encoding glucagon-like peptide-1 (GLP-1), nucleic acid construct comprising same for production of glucagon-like peptide-1 (GLP-1), human cells comprising said construct and insulin-producing constructs, and methods of use thereof
|
|
CA2689909C
(en)
|
2007-06-08 |
2016-04-05 |
Ascendis Pharma As |
Long-acting polymeric prodrugs of exendin
|
|
US7994122B2
(en)
|
2007-06-15 |
2011-08-09 |
Zealand Pharma A/S |
Glucagon analogues
|
|
US20100196405A1
(en)
|
2007-07-10 |
2010-08-05 |
Kingman Ng |
GLP-1 Fc FUSION PROTEIN FORMULATION
|
|
EP2185178B1
(en)
|
2007-08-03 |
2017-08-23 |
Eli Lilly And Company |
Use of an fgf-21 compound and a glp-1 compound for the treatment of obesity
|
|
CN101366692A
(zh)
|
2007-08-15 |
2009-02-18 |
江苏豪森药业股份有限公司 |
一种稳定的艾塞那肽制剂
|
|
MY165889A
(en)
|
2007-08-30 |
2018-05-18 |
Curedm Group Holdings Llc |
Compositions and methods of using proislet peptides and analogs thereof
|
|
ES2532116T3
(es)
|
2007-09-05 |
2015-03-24 |
Novo Nordisk A/S |
Péptidos derivados con A-B-C-D y sus usos terapéuticos
|
|
JP2010538069A
(ja)
|
2007-09-07 |
2010-12-09 |
イプセン ファルマ ソシエテ パール アクシオン サンプリフィエ |
エキセンディン−4およびエキセンディン−3の類似体
|
|
CA2703338A1
(en)
|
2007-10-24 |
2009-04-30 |
Mannkind Corporation |
Method of preventing adverse effects by glp-1
|
|
US8785396B2
(en)
|
2007-10-24 |
2014-07-22 |
Mannkind Corporation |
Method and composition for treating migraines
|
|
BRPI0818874A2
(pt)
|
2007-10-24 |
2015-05-05 |
Mannkind Corp |
Liberação de agentes ativos
|
|
JP5669582B2
(ja)
|
2007-10-30 |
2015-02-12 |
インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation |
グルカゴンアンタゴニスト
|
|
EP2214691B1
(en)
|
2007-10-30 |
2015-09-30 |
Indiana University Research and Technology Corporation |
Compounds exhibiting glucagon antagonist and glp-1 agonist activity
|
|
MX2010005245A
(es)
|
2007-11-16 |
2010-06-01 |
Novo Nordisk As |
Composiciones farmaceuticas que comprenden peptidos glp-1 o exendin-4 y un peptido de insulina basal.
|
|
EP2224945B1
(en)
|
2007-11-23 |
2012-05-16 |
Michael Rothkopf |
Methods of enhancing diabetes resolution
|
|
CN101444618B
(zh)
|
2007-11-26 |
2012-06-13 |
杭州九源基因工程有限公司 |
含有艾塞那肽的药物制剂
|
|
JP2011506442A
(ja)
|
2007-12-11 |
2011-03-03 |
コンジュケム バイオテクノロジーズ インコーポレイテッド |
インスリン分泌性ペプチド結合体の製剤
|
|
EP2229407B1
(de)
|
2008-01-09 |
2016-11-16 |
Sanofi-Aventis Deutschland GmbH |
Neue insulinderivate mit extrem verzögertem zeit- / wirkungsprofil
|
|
AU2009210570B2
(en)
|
2008-01-30 |
2014-11-20 |
Indiana University Research And Technology Corporation |
Ester-based insulin prodrugs
|
|
HRP20191052T1
(hr)
|
2008-02-01 |
2019-11-01 |
Ascendis Pharma As |
Predlijek koji obuhvaća samocijepajuću poveznicu
|
|
EP2247737B1
(en)
|
2008-02-06 |
2018-06-20 |
Biocon Limited |
Fermentation medias and processes thereof
|
|
WO2009114959A1
(zh)
|
2008-03-20 |
2009-09-24 |
中国人民解放军军事医学科学院毒物药物研究所 |
可注射用缓释药物制剂及其制备方法
|
|
CA2720864C
(en)
|
2008-04-07 |
2017-07-04 |
National Institute Of Immunology |
Compositions useful for the treatment of diabetes and other chronic disorder
|
|
JP5671451B2
(ja)
|
2008-05-07 |
2015-02-18 |
メリオン・リサーチ・Iii・リミテッド |
GnRH関連化合物の組成物および調製プロセス
|
|
US20110263496A1
(en)
|
2008-05-21 |
2011-10-27 |
Amylin Pharmaceuticals, Inc. |
Exendins to lower cholesterol and triglycerides
|
|
WO2009143014A1
(en)
|
2008-05-23 |
2009-11-26 |
Amylin Pharmaceuticals, Inc. |
Glp-1 receptor agonist bioassays
|
|
DK2293833T3
(en)
|
2008-06-13 |
2016-05-23 |
Mannkind Corp |
DRY POWDER INHALER AND MEDICINAL ADMINISTRATION SYSTEM
|
|
US8485180B2
(en)
|
2008-06-13 |
2013-07-16 |
Mannkind Corporation |
Dry powder drug delivery system
|
|
MX337038B
(es)
|
2008-06-17 |
2016-02-10 |
Univ Indiana Res & Tech Corp |
Co-antagonistas de receptor de glucagon/glp-1.
|
|
CN104447980A
(zh)
|
2008-06-17 |
2015-03-25 |
印第安纳大学研究及科技有限公司 |
在生理pH缓冲液中具有增强的溶解性和稳定性的胰高血糖素类似物
|
|
EP2300035B1
(en)
|
2008-06-17 |
2015-08-12 |
Indiana University Research and Technology Corporation |
Gip-based mixed agonists for treatment of metabolic disorders and obesity
|
|
JP5604297B2
(ja)
|
2008-06-17 |
2014-10-08 |
株式会社糖鎖工学研究所 |
糖鎖付加glp−1ペプチド
|
|
WO2009158704A2
(en)
|
2008-06-27 |
2009-12-30 |
Duke University |
Therapeutic agents comprising elastin-like peptides
|
|
US20110129522A1
(en)
|
2008-07-21 |
2011-06-02 |
Transpharma Medical Ltd. |
Transdermal system for extended delivery of incretins and incretn mimetic peptides
|
|
WO2010013012A2
(en)
|
2008-08-01 |
2010-02-04 |
Lund University Bioscience Ab |
Novel polypeptides and uses thereof
|
|
CN101670096B
(zh)
|
2008-09-11 |
2013-01-16 |
杭州九源基因工程有限公司 |
含有艾塞那肽的药物制剂
|
|
PT2349324T
(pt)
|
2008-10-17 |
2017-12-06 |
Sanofi Aventis Deutschland |
Combinação de uma insulina e de um agonista do glp-1
|
|
EP2373681B1
(en)
|
2008-12-10 |
2017-01-18 |
Glaxosmithkline LLC |
Pharmaceutical compositions of albiglutide
|
|
KR20110126592A
(ko)
|
2008-12-15 |
2011-11-23 |
질랜드 파마 에이/에스 |
글루카곤 유사체
|
|
EP2370462B1
(en)
|
2008-12-15 |
2014-07-16 |
Zealand Pharma A/S |
Glucagon analogues
|
|
AU2008365555B2
(en)
|
2008-12-15 |
2016-01-14 |
Zealand Pharma A/S |
Glucagon analogues
|
|
MX2011006320A
(es)
|
2008-12-15 |
2011-09-22 |
Zealand Pharma As |
Analogos de glucagon.
|
|
SG172291A1
(en)
|
2008-12-19 |
2011-07-28 |
Univ Indiana Res & Tech Corp |
Amide based glucagon superfamily peptide prodrugs
|
|
CN101538323B
(zh)
|
2009-01-13 |
2012-05-09 |
深圳翰宇药业股份有限公司 |
一种纯化艾塞那肽的方法
|
|
DE102009006602A1
(de)
|
2009-01-29 |
2010-08-05 |
Bayer Schering Pharma Aktiengesellschaft |
Alkylamino-substituierte Dicyanopyridine und deren Aminosäureester-Prodrugs
|
|
WO2010096052A1
(en)
|
2009-02-19 |
2010-08-26 |
Merck Sharp & Dohme Corp. |
Oxyntomodulin analogs
|
|
AU2010221254B2
(en)
|
2009-03-04 |
2014-04-03 |
Mannkind Corporation |
An improved dry powder drug delivery system
|
|
WO2010100241A1
(en)
|
2009-03-05 |
2010-09-10 |
Sanofi-Aventis Deutschland Gmbh |
Drug delivery device with retractable needle
|
|
EP2413955A4
(en)
|
2009-04-01 |
2012-12-26 |
Amylin Pharmaceuticals Inc |
N-TERMINAL CONFORMATION RESTRICTED GLP-1 RECEPTOR AGONIST COMPOUNDS
|
|
US8992886B2
(en)
|
2009-04-06 |
2015-03-31 |
Board Of Regents, The University Of Texas System |
Cyclic peptide analogues for non-invasive imaging of pancreatic beta-cells
|
|
US9012606B2
(en)
|
2009-04-22 |
2015-04-21 |
Alteogen, Inc. |
In vivo half life increased fusion protein or peptide maintained by sustained in vivo release, and method for increasng in vivo half-life using same
|
|
CN101870728A
(zh)
|
2009-04-23 |
2010-10-27 |
派格生物医药(苏州)有限公司 |
新型Exendin变体及其缀合物
|
|
CN101559041B
(zh)
|
2009-05-19 |
2014-01-15 |
中国科学院过程工程研究所 |
粒径均一的多肽药物缓释微球或微囊制剂及制备方法
|
|
CN105536110B
(zh)
|
2009-05-20 |
2020-01-17 |
赛诺菲-安万特德国有限公司 |
用于药物递送装置中药物容纳筒的塞子
|
|
WO2010133676A1
(en)
|
2009-05-20 |
2010-11-25 |
Sanofi-Aventis Deutschland Gmbh |
A system comprising a drug delivery device and a cartridge provided with a bung and a method of identifying the cartridge
|
|
EP2435061A4
(en)
|
2009-05-28 |
2013-03-27 |
Amylin Pharmaceuticals Inc |
DAMPING GLP-1 RECEPTOR AGONIST COMPOUNDS
|
|
CN102802657A
(zh)
|
2009-06-11 |
2012-11-28 |
诺沃-诺迪斯克有限公司 |
用于治疗2型糖尿病的glp-1和fgf21组合
|
|
MX2011013625A
(es)
|
2009-06-16 |
2012-01-20 |
Univ Indiana Res & Tech Corp |
Compuestos glucagon activo de receptor de gip.
|
|
JP5932642B2
(ja)
|
2009-07-02 |
2016-06-08 |
アンジオケム インコーポレーテッド |
多量体ペプチドコンジュゲートおよびその使用
|
|
AP3329A
(en)
|
2009-07-13 |
2015-06-30 |
Zealand Pharma As |
Acylated glucagon analogues
|
|
CN101601646B
(zh)
|
2009-07-22 |
2011-03-23 |
南京凯瑞尔纳米生物技术有限公司 |
治疗糖尿病的鼻腔滴剂及其制备方法
|
|
WO2011011675A1
(en)
|
2009-07-23 |
2011-01-27 |
Zelos Therapeutics, Inc. |
Pharmaceutically acceptable formulations/compositions for peptidyl drugs
|
|
PE20120918A1
(es)
|
2009-07-31 |
2012-08-14 |
Sanofi Aventis Deutschland |
Profarmacos que comprenden un conjugado de insulina-conector
|
|
WO2011017835A1
(en)
|
2009-08-11 |
2011-02-17 |
Nanjing University |
Preparation method of protein or peptide nanoparticles for in vivo drug delivery by unfolding and refolding
|
|
CN101993485B
(zh)
|
2009-08-20 |
2013-04-17 |
重庆富进生物医药有限公司 |
促胰岛素分泌肽类似物同源二聚体及其用途
|
|
US20120148586A1
(en)
|
2009-08-27 |
2012-06-14 |
Joyce Ching Tsu Chou |
Glucagon-like protein-1 receptor (glp-1r) agonists for treating autoimmune disorders
|
|
MX2012003939A
(es)
|
2009-09-30 |
2012-07-30 |
Glaxo Group Ltd |
Fusiones y conjugados de farmaco.
|
|
DK2490708T3
(da)
|
2009-10-22 |
2013-04-15 |
Biodel Inc |
Stabiliserede glucagon-opløsninger
|
|
US20110097386A1
(en)
|
2009-10-22 |
2011-04-28 |
Biodel, Inc. |
Stabilized glucagon solutions
|
|
US9610329B2
(en)
|
2009-10-22 |
2017-04-04 |
Albireo Pharma, Inc. |
Stabilized glucagon solutions
|
|
EP2495255A4
(en)
|
2009-10-30 |
2013-05-15 |
Otsuka Chemical Co Ltd |
GLYCOSYLATED FORM OF AN ANTIGENIC GLP-1 ANALOG
|
|
KR101426180B1
(ko)
|
2009-11-02 |
2014-07-31 |
화이자 인코포레이티드 |
디옥사-비시클로[3.2.1]옥탄-2,3,4-트리올 유도체
|
|
WO2011056713A2
(en)
|
2009-11-03 |
2011-05-12 |
Amylin Pharmaceuticals, Inc. |
Glp-1 receptor agonist compounds for obstructive sleep apnea
|
|
WO2011058083A1
(de)
|
2009-11-13 |
2011-05-19 |
Sanofi-Aventis Deutschland Gmbh |
Pharmazeutische zusammensetzung umfassend einen glp-1-agonisten, ein insulin und methionin
|
|
SG10201500871TA
(en)
|
2009-11-13 |
2015-04-29 |
Sanofi Aventis Deutschland |
Pharmaceutical composition comprising a glp-1 agonist and methionine
|
|
RU2012130011A
(ru)
|
2009-12-15 |
2014-01-27 |
МЕТАБОЛИК СОЛЮШНЗ ДЕВЕЛОПМЕНТ КОМПАНИ, ЭлЭлСи |
Ppar-снижающие тиазолидиндионы и комбинации для лечения сахарного диабета и других нарушений обмена веществ
|
|
AU2010340061A1
(en)
|
2009-12-15 |
2012-06-21 |
Metabolic Solutions Development Company, Llc |
PPAR-sparing thiazolidinediones and combinations for the treatment of obesity and other metabolic diseases
|
|
JP2013514368A
(ja)
|
2009-12-15 |
2013-04-25 |
メタボリック ソリューションズ ディベロップメント カンパニー, エルエルシー |
神経変性疾患を処置するための、ppar温存チアゾリジンジオンおよび組み合わせ物
|
|
HUE038042T2
(hu)
|
2009-12-15 |
2018-09-28 |
Cirius Therapeutics Inc |
PPAR helyettesítõ tiazolidindion sók metabolikus betegségek kezelésére
|
|
MX2012006634A
(es)
|
2009-12-16 |
2012-06-21 |
Novo Nordisk As |
Derivados de peptidos tipo glucagon 1 de doble acilato.
|
|
CN102933200B
(zh)
|
2009-12-18 |
2015-11-25 |
莱迪杜德制药公司 |
包含磷脂的单相凝胶组合物
|
|
WO2011075393A2
(en)
|
2009-12-18 |
2011-06-23 |
Indiana University Research And Technology Corporation |
Glucagon/glp-1 receptor co-agonists
|
|
CN101798588B
(zh)
*
|
2009-12-21 |
2015-09-09 |
上海仁会生物制药股份有限公司 |
Glp-1受体激动剂生物学活性测定方法
|
|
AR079344A1
(es)
|
2009-12-22 |
2012-01-18 |
Lilly Co Eli |
Analogo peptidico de oxintomodulina, composicion farmaceutica que lo comprende y uso para preparar un medicamento util para tratar diabetes no insulinodependiente y/u obesidad
|
|
AR079345A1
(es)
|
2009-12-22 |
2012-01-18 |
Lilly Co Eli |
Analogo peptidico de oxintomodulina
|
|
AU2011206979B2
(en)
|
2010-01-20 |
2015-09-10 |
Zealand Pharma A/S |
Treatment of cardiac conditions
|
|
JP2013518115A
(ja)
|
2010-01-27 |
2013-05-20 |
インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーション |
代謝疾患及び肥満の治療のためのグルカゴンアンタゴニスト‐gipアゴニスト複合体及び組成物
|
|
US9775949B2
(en)
|
2010-02-01 |
2017-10-03 |
Sanofi-Aventis Deutschland Gmbh |
Cartridge holder, drug delivery device and method for securing a cartridge in a cartridge holder
|
|
WO2011109784A1
(en)
|
2010-03-05 |
2011-09-09 |
Conjuchem, Llc |
Formulation of insulinotropic peptide conjugates
|
|
US8840601B2
(en)
|
2010-03-24 |
2014-09-23 |
Shifamed Holdings, Llc |
Intravascular tissue disruption
|
|
AR080592A1
(es)
*
|
2010-03-26 |
2012-04-18 |
Lilly Co Eli |
Peptido con actividad para el gip-r y glp-1-r, formulacion famaceutica que lo comprende, su uso para preparar un medicamento util para el tratamiento de diabetes mellitus y para inducir la perdida de peso
|
|
RU2559320C2
(ru)
|
2010-03-26 |
2015-08-10 |
Ново Нордиск А/С |
Новые аналоги глюкагона
|
|
RU2012153753A
(ru)
|
2010-05-13 |
2014-06-20 |
Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн |
Пептиды глюкагонового суперсемейства, обладающие активностью в отношении сопряженных с g-белком рецепторов
|
|
ES2661228T3
(es)
|
2010-05-13 |
2018-03-28 |
Indiana University Research And Technology Corporation |
Péptidos de la superfamilia de glucagón que muestran actividad de receptor nuclear de hormona
|
|
AU2011202239C1
(en)
|
2010-05-19 |
2017-03-16 |
Sanofi |
Long-acting formulations of insulins
|
|
EP2571900A1
(en)
|
2010-05-20 |
2013-03-27 |
Glaxo Group Limited |
Improved anti-serum albumin binding variants
|
|
WO2011156407A2
(en)
|
2010-06-09 |
2011-12-15 |
Amylin Pharmaceuticals, Inc. |
Glp-1 receptor agonists to treat pancre-atitis
|
|
CN101891823B
(zh)
|
2010-06-11 |
2012-10-03 |
北京东方百泰生物科技有限公司 |
一种Exendin-4及其类似物融合蛋白
|
|
US8636711B2
(en)
|
2010-06-14 |
2014-01-28 |
Legacy Emanuel Hospital & Health Center |
Stabilized glucagon solutions and uses therefor
|
|
IL223742A
(en)
|
2010-06-21 |
2016-06-30 |
Mannkind Corp |
A dry powder inhaler and preparation for it
|
|
AR081975A1
(es)
|
2010-06-23 |
2012-10-31 |
Zealand Pharma As |
Analogos de glucagon
|
|
US9234023B2
(en)
|
2010-06-24 |
2016-01-12 |
Biousian Biosystems, Inc. |
Glucagon-like peptide-1 glycopeptides
|
|
CA2796894A1
(en)
|
2010-06-24 |
2011-12-29 |
Indiana University Research And Technology Corporation |
Amide based glucagon superfamily peptide prodrugs
|
|
WO2011163473A1
(en)
|
2010-06-25 |
2011-12-29 |
Indiana University Research And Technology Corporation |
Glucagon analogs exhibiting enhanced solubility and stability in physiological ph buffers
|
|
US20130137645A1
(en)
|
2010-07-19 |
2013-05-30 |
Mary S. Rosendahl |
Modified peptides and proteins
|
|
US20120046225A1
(en)
|
2010-07-19 |
2012-02-23 |
The Regents Of The University Of Colorado, A Body Corporate |
Stable glucagon formulations for the treatment of hypoglycemia
|
|
EA201390182A1
(ru)
|
2010-07-28 |
2014-01-30 |
АМИЛИН ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи |
Соединения-агонисты рецептора glp-1, содержащие стабилизированные области
|
|
CN102397558B
(zh)
|
2010-09-09 |
2013-08-14 |
中国人民解放军军事医学科学院毒物药物研究所 |
Exendin-4类似物的定位聚乙二醇化修饰物及其用途
|
|
EP2438930A1
(en)
|
2010-09-17 |
2012-04-11 |
Sanofi-Aventis Deutschland GmbH |
Prodrugs comprising an exendin linker conjugate
|
|
CN106986940A
(zh)
|
2010-09-28 |
2017-07-28 |
艾米琳制药有限责任公司 |
具有增强的作用持续时间的工程化多肽
|
|
WO2012059762A1
(en)
|
2010-11-03 |
2012-05-10 |
Arecor Limited |
Novel composition comprising glucagon
|
|
CN107854454A
(zh)
|
2010-11-09 |
2018-03-30 |
曼金德公司 |
用于治疗偏头痛的包含血清素受体激动剂和二酮哌嗪的组合物
|
|
EP2460552A1
(en)
|
2010-12-06 |
2012-06-06 |
Sanofi-Aventis Deutschland GmbH |
Drug delivery device with locking arrangement for dose button
|
|
CN102552883B
(zh)
|
2010-12-09 |
2014-02-19 |
天津药物研究院 |
一种多肽复合物、药物组合物、其制备方法和应用
|
|
RS56998B1
(sr)
|
2010-12-16 |
2018-05-31 |
Novo Nordisk As |
Čvrste kompozicije koje sadrže agonist glp-1 i so n-(8-(2-hidroksibenzoil)amino)kaprilne kiseline
|
|
WO2012088157A2
(en)
|
2010-12-22 |
2012-06-28 |
Amylin Pharmaceuticals, Inc. |
Glp-1 receptor agonists for islet cell transplantation
|
|
EA201390941A1
(ru)
|
2010-12-22 |
2013-12-30 |
Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн |
Аналоги глюкагона, проявляющие активность на рецепторе gip
|
|
CN102532301B
(zh)
|
2010-12-31 |
2014-09-03 |
上海医药工业研究院 |
一类新型的Exendin-4类似物及其制备方法
|
|
US20120208755A1
(en)
|
2011-02-16 |
2012-08-16 |
Intarcia Therapeutics, Inc. |
Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
|
|
CN102100906A
(zh)
|
2011-02-18 |
2011-06-22 |
深圳翰宇药业股份有限公司 |
一种艾塞那肽的药用制剂及其制备方法
|
|
AU2012225268B2
(en)
|
2011-03-10 |
2016-10-20 |
Xeris Pharmaceuticals, Inc. |
Stable formulations for parenteral injection of peptide drugs
|
|
CN102718858B
(zh)
|
2011-03-29 |
2014-07-02 |
天津药物研究院 |
胰高血糖素样肽-1类似物单体、二聚体及其制备方法与应用
|
|
CN102718868A
(zh)
|
2011-03-30 |
2012-10-10 |
上海华谊生物技术有限公司 |
定点单取代聚乙二醇化Exendin类似物及其制备方法
|
|
US9790262B2
(en)
|
2011-04-05 |
2017-10-17 |
Longevity Biotech, Inc. |
Compositions comprising glucagon analogs and methods of making and using the same
|
|
EP2696897A2
(en)
|
2011-04-11 |
2014-02-19 |
Yeda Research and Development Co. Ltd. |
Albumin binding probes and drug conjugates thereof
|
|
WO2012150503A2
(en)
|
2011-05-03 |
2012-11-08 |
Zealand Pharma A/S |
Glu-glp-1 dual agonist signaling-selective compounds
|
|
CN102766204B
(zh)
|
2011-05-05 |
2014-10-15 |
天津药物研究院 |
胰高血糖素样肽-1突变体多肽及其制备方法和其应用
|
|
KR102497726B1
(ko)
|
2011-05-18 |
2023-02-07 |
메더리스 다이어비티즈, 엘엘씨 |
인슐린 저항성에 대한 개선된 펩티드 제약
|
|
US20140221282A1
(en)
|
2011-05-25 |
2014-08-07 |
Astrazeneca Pharmaceuticals Lp |
Long duration dual hormone conjugates
|
|
UA113626C2
(xx)
|
2011-06-02 |
2017-02-27 |
|
Композиція для лікування діабету, що містить кон'югат інсуліну тривалої дії та кон'югат інсулінотропного пептиду тривалої дії
|
|
CN103764673A
(zh)
|
2011-06-10 |
2014-04-30 |
北京韩美药品有限公司 |
葡萄糖依赖性促胰岛素多肽类似物、其药物组合物及应用
|
|
CA2838503C
(en)
|
2011-06-10 |
2020-02-18 |
Hanmi Science Co., Ltd. |
Novel oxyntomodulin derivatives and pharmaceutical composition for treating obesity comprising the same
|
|
WO2012174478A2
(en)
|
2011-06-17 |
2012-12-20 |
Halozyme, Inc. |
Stable formulations of a hyaluronan-degrading enzyme
|
|
ES2710356T3
(es)
|
2011-06-17 |
2019-04-24 |
Hanmi Science Co Ltd |
Conjugado que comprende oxintomodulina y un fragmento de inmunoglobulina, y uso del mismo
|
|
MX2013015168A
(es)
|
2011-06-22 |
2014-03-31 |
Univ Indiana Res & Tech Corp |
Co-agonista del receptor de glucagon/glp-1.
|
|
ME02816B
(me)
|
2011-06-22 |
2018-01-20 |
Univ Indiana Res & Tech Corp |
Koagonisti receptora za glukagon/glp-1 receptora
|
|
CN103906528A
(zh)
|
2011-06-24 |
2014-07-02 |
安米林药品有限责任公司 |
用glp-1受体激动剂的缓释制剂治疗糖尿病的方法
|
|
KR101357117B1
(ko)
|
2011-06-28 |
2014-02-06 |
비앤엘델리팜 주식회사 |
폴리에틸렌글라이콜 또는 이의 유도체로 페길화된 엑센딘-4 유사체, 이의 제조방법 및 이를 유효성분으로 함유하는 당뇨병 예방 또는 치료용 약학적 조성물
|
|
US9944687B2
(en)
|
2011-07-04 |
2018-04-17 |
Imperial Innovations Limited |
Compounds and their effects on feeding behaviour
|
|
US9382304B2
(en)
|
2011-07-08 |
2016-07-05 |
Amylin Pharmaceuticals, Llc |
Engineered polypeptides having enhanced duration of action with reduced immunogenicity
|
|
CA2843586A1
(fr)
|
2011-08-10 |
2013-02-14 |
Adocia |
Solution injectable d'au moins une insuline basale
|
|
US20130084277A1
(en)
|
2011-08-24 |
2013-04-04 |
Phasebio Pharmaceuticals, Inc. |
Formulations of active agents for sustained release
|
|
WO2013029279A1
(zh)
|
2011-09-03 |
2013-03-07 |
深圳市健元医药科技有限公司 |
新的glp-ⅰ类似物及其制备方法和用途
|
|
MY167234A
(en)
|
2011-09-23 |
2018-08-14 |
Novo Nordisk As |
Novel glucagon analogues
|
|
US20130296236A1
(en)
|
2011-10-28 |
2013-11-07 |
Louise SILVESTRE |
Treatment protocol of diabetes type 2
|
|
CN102363633B
(zh)
|
2011-11-16 |
2013-11-20 |
天津拓飞生物科技有限公司 |
胰高血糖素样肽-1突变体多肽及其制备方法、药物组合物和其应用
|
|
HK1198810A1
(en)
|
2011-11-17 |
2015-06-12 |
Indiana University Research And Technology Corporation |
Glucagon superfamily peptides exhibiting glucocorticoid receptor activity
|
|
CA2852716C
(en)
|
2011-11-29 |
2015-11-17 |
Jurox Pty Ltd |
Methods of preserving injectable pharmaceutical compositions comprising a cyclodextrin and a hydrophobic drug
|
|
PL2791160T3
(pl)
|
2011-12-16 |
2022-06-20 |
Modernatx, Inc. |
Kompozycje zmodyfikowanego mrna
|
|
US9163227B2
(en)
|
2011-12-22 |
2015-10-20 |
Covx Technologies Ireland Limited |
Anti-diabetic compounds
|
|
HK1200369A1
(en)
|
2011-12-23 |
2015-10-09 |
Zealand Pharma A/S |
Glucagon analogues
|
|
CN104159570A
(zh)
|
2011-12-29 |
2014-11-19 |
陈献 |
稳定的胰高血糖素纳米乳液
|
|
CN107583039A
(zh)
|
2012-01-09 |
2018-01-16 |
阿道恰公司 |
Ph为7且至少含pi为5.8至8.5之基础胰岛素和取代共聚(氨基酸)的可注射溶液
|
|
WO2013148966A1
(en)
|
2012-03-28 |
2013-10-03 |
Amylin Pharmaceuticals, Llc |
Transmucosal delivery of engineered polypeptides
|
|
WO2013148871A1
(en)
|
2012-03-28 |
2013-10-03 |
Amylin Pharmaceuticals, Llc |
Engineered polypeptides
|
|
AU2013243949A1
(en)
|
2012-04-02 |
2014-10-30 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of biologics and proteins associated with human disease
|
|
HK1206779A1
(en)
|
2012-04-02 |
2016-01-15 |
Modernatx, Inc. |
Modified polynucleotides for the production of nuclear proteins
|
|
CN102649947A
(zh)
|
2012-04-20 |
2012-08-29 |
无锡和邦生物科技有限公司 |
一种用于测定glp-1及其功能类似物生物活性的细胞株及其应用
|
|
WO2013163162A1
(en)
|
2012-04-24 |
2013-10-31 |
Amylin Pharmaceuticals, Llc |
Site-specific enzymatic modification of exendins and analogs thereof
|
|
US20130289241A1
(en)
|
2012-04-26 |
2013-10-31 |
Shanghai Ambiopharm, Inc. |
Method for preparing exenatide
|
|
WO2013182217A1
(en)
|
2012-04-27 |
2013-12-12 |
Sanofi-Aventis Deutschland Gmbh |
Quantification of impurities for release testing of peptide products
|
|
US8901484B2
(en)
|
2012-04-27 |
2014-12-02 |
Sanofi-Aventis Deutschland Gmbh |
Quantification of impurities for release testing of peptide products
|
|
CN104540850B
(zh)
|
2012-05-03 |
2018-05-18 |
西兰制药公司 |
胰高血糖素样肽2(glp-2)类似物
|
|
WO2013164483A1
(en)
|
2012-05-03 |
2013-11-07 |
Zealand Pharma A/S |
Gip-glp-1 dual agonist compounds and methods
|
|
EP2664374A1
(en)
|
2012-05-15 |
2013-11-20 |
F. Hoffmann-La Roche AG |
Lysin-glutamic acid dipeptide derivatives
|
|
CN103421094A
(zh)
|
2012-05-24 |
2013-12-04 |
上海医药工业研究院 |
一种具有epo类似活性的多肽化合物
|
|
US20150174209A1
(en)
|
2012-05-25 |
2015-06-25 |
Amylin Pharmaceuticals. Llc |
Insulin-pramlintide compositions and methods for making and using them
|
|
MX2014015423A
(es)
|
2012-06-14 |
2015-04-09 |
Sanofi Sa |
Analogos de peptido de exedina-4.
|
|
CN104583232B
(zh)
|
2012-06-21 |
2018-04-13 |
印第安纳大学研究及科技有限公司 |
展现gip受体活性的胰高血糖素类似物
|
|
DK2864350T3
(en)
|
2012-06-21 |
2018-05-28 |
Univ Indiana Res & Tech Corp |
ANALOGUE OF GLUCAGON EXPRESSING GIP RECEPTOR ACTIVITY
|
|
SG11201500218VA
(en)
|
2012-07-12 |
2015-03-30 |
Mannkind Corp |
Dry powder drug delivery systems and methods
|
|
IN2015DN00544A
(lt)
|
2012-07-23 |
2015-06-26 |
Zealand Pharma As |
|
|
AR094821A1
(es)
|
2012-07-25 |
2015-09-02 |
Hanmi Pharm Ind Co Ltd |
Formulación líquida de un conjugado de péptido insulinotrópico de acción prolongada
|
|
KR101968344B1
(ko)
|
2012-07-25 |
2019-04-12 |
한미약품 주식회사 |
옥신토모듈린 유도체를 포함하는 고지혈증 치료용 조성물
|
|
AR092862A1
(es)
|
2012-07-25 |
2015-05-06 |
Hanmi Pharm Ind Co Ltd |
Formulacion liquida de insulina de accion prolongada y un peptido insulinotropico y metodo de preparacion
|
|
WO2014027253A1
(en)
|
2012-08-14 |
2014-02-20 |
Wockhardt Limited |
Pharmaceutical microparticulate compositions of polypeptides
|
|
EP2931300A1
(en)
|
2012-08-14 |
2015-10-21 |
Wockhardt Limited |
Pharmaceutical microparticulate compositions of polypeptides
|
|
CN102816244A
(zh)
|
2012-08-23 |
2012-12-12 |
无锡和邦生物科技有限公司 |
一种Exendin-4肽与人血清白蛋白HSA的融合蛋白及其制备方法
|
|
CN102827270A
(zh)
|
2012-09-13 |
2012-12-19 |
无锡和邦生物科技有限公司 |
一种聚乙二醇化艾塞那肽衍生物及其用途
|
|
WO2014041375A1
(en)
|
2012-09-17 |
2014-03-20 |
Imperial Innovations Limited |
Peptide analogues of glucagon and glp1
|
|
TWI608013B
(zh)
|
2012-09-17 |
2017-12-11 |
西蘭製藥公司 |
升糖素類似物
|
|
WO2014049610A2
(en)
|
2012-09-26 |
2014-04-03 |
Cadila Healthcare Limited |
Peptides as gip, glp-1 and glucagon receptors triple-agonist
|
|
UA116217C2
(uk)
|
2012-10-09 |
2018-02-26 |
Санофі |
Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону
|
|
MY197849A
(en)
|
2012-11-06 |
2023-07-20 |
Hanmi Pharm Ind Co Ltd |
Liquid formulation of protein conjugate comprising the oxyntomodulin and an immunoglobulin fragment
|
|
KR101993393B1
(ko)
|
2012-11-06 |
2019-10-01 |
한미약품 주식회사 |
옥신토모듈린 유도체를 포함하는 당뇨병 또는 비만성 당뇨병 치료용 조성물
|
|
JP6525456B2
(ja)
|
2012-11-20 |
2019-06-05 |
メデリス ダイアビーティーズ,エルエルシー |
インスリン抵抗性のための改善されたペプチド製剤
|
|
TWI617574B
(zh)
|
2012-12-11 |
2018-03-11 |
梅迪繆思有限公司 |
用於治療肥胖之升糖素與glp-1共促效劑
|
|
SG11201503526UA
(en)
|
2012-12-21 |
2015-06-29 |
Sanofi Sa |
Dual glp1/gip or trigonal glp1/gip/glucagon agonists
|
|
CN103908657A
(zh)
|
2012-12-31 |
2014-07-09 |
复旦大学附属华山医院 |
胰升糖素样肽-1类似物在制备眼科疾病药物中的用途
|
|
US9714277B2
(en)
|
2013-03-14 |
2017-07-25 |
Medimmune Limited |
Pegylated glucagon and GLP-1 co-agonists for the treatment of obesity
|
|
KR20150131213A
(ko)
|
2013-03-14 |
2015-11-24 |
인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 |
인슐린-인크레틴 접합체들
|
|
US20160058881A1
(en)
|
2013-03-15 |
2016-03-03 |
Indiana University Research And Technology Corporation |
Prodrugs with prolonged action
|
|
WO2014170496A1
(en)
|
2013-04-18 |
2014-10-23 |
Novo Nordisk A/S |
Stable, protracted glp-1/glucagon receptor co-agonists for medical use
|
|
JP2014227368A
(ja)
|
2013-05-21 |
2014-12-08 |
国立大学法人帯広畜産大学 |
糖尿病および高血糖状態の処置のためのグルカゴンアナログ
|
|
CN103304660B
(zh)
|
2013-07-12 |
2016-08-10 |
上海昂博生物技术有限公司 |
一种利拉鲁肽的合成方法
|
|
CN103405753B
(zh)
|
2013-08-13 |
2016-05-11 |
上海仁会生物制药股份有限公司 |
稳定的促胰岛素分泌肽水针药物组合物
|
|
ES2688708T3
(es)
|
2013-10-17 |
2018-11-06 |
Zealand Pharma A/S |
Análogos de glucagón acilados
|
|
US9988429B2
(en)
|
2013-10-17 |
2018-06-05 |
Zealand Pharma A/S |
Glucagon analogues
|
|
US10131702B2
(en)
|
2013-11-06 |
2018-11-20 |
Zealand Pharma A/S |
Glucagon-GLP-1-GIP triple agonist compounds
|
|
WO2015086733A1
(en)
|
2013-12-13 |
2015-06-18 |
Sanofi |
Dual glp-1/glucagon receptor agonists
|
|
WO2015086732A1
(en)
|
2013-12-13 |
2015-06-18 |
Sanofi |
Exendin-4 peptide analogues
|
|
WO2015086729A1
(en)
|
2013-12-13 |
2015-06-18 |
Sanofi |
Dual glp-1/gip receptor agonists
|
|
WO2015086731A1
(en)
|
2013-12-13 |
2015-06-18 |
Sanofi |
Exendin-4 peptide analogues as dual glp-1/glucagon receptor agonists
|
|
WO2015086730A1
(en)
|
2013-12-13 |
2015-06-18 |
Sanofi |
Non-acylated exendin-4 peptide analogues
|
|
EP3080150B1
(en)
|
2013-12-13 |
2018-08-01 |
Sanofi |
Exendin-4 peptide analogues as dual glp-1/gip receptor agonists
|
|
CN103665148B
(zh)
|
2013-12-17 |
2016-05-11 |
中国药科大学 |
一种可口服给药的降糖多肽及其制法和用途
|
|
CN103980358B
(zh)
|
2014-01-03 |
2016-08-31 |
杭州阿诺生物医药科技股份有限公司 |
一种制备利拉鲁肽的方法
|
|
SG11201604710XA
(en)
|
2014-01-09 |
2016-07-28 |
Sanofi Sa |
Stabilized pharmaceutical formulations of insulin analogues and/or insulin derivatives
|
|
SG11201604708VA
(en)
|
2014-01-09 |
2016-07-28 |
Sanofi Sa |
Stabilized glycerol free pharmaceutical formulations of insulin analogues and/or insulin derivatives
|
|
GB201404002D0
(en)
|
2014-03-06 |
2014-04-23 |
Imp Innovations Ltd |
Novel compounds
|
|
TW201625670A
(zh)
|
2014-04-07 |
2016-07-16 |
賽諾菲公司 |
衍生自exendin-4之雙重glp-1/升糖素受體促效劑
|
|
TW201625668A
(zh)
|
2014-04-07 |
2016-07-16 |
賽諾菲公司 |
作為胜肽性雙重glp-1/昇糖素受體激動劑之艾塞那肽-4衍生物
|
|
TW201625669A
(zh)
|
2014-04-07 |
2016-07-16 |
賽諾菲公司 |
衍生自艾塞那肽-4(Exendin-4)之肽類雙重GLP-1/升糖素受體促效劑
|
|
US9932381B2
(en)
|
2014-06-18 |
2018-04-03 |
Sanofi |
Exendin-4 derivatives as selective glucagon receptor agonists
|
|
CN104926934B
(zh)
|
2014-09-23 |
2016-11-09 |
蒋先兴 |
胃泌酸调节素类似物
|
|
JP2017536343A
(ja)
|
2014-10-10 |
2017-12-07 |
ノヴォ ノルディスク アー/エス |
安定したglp−1ベースのglp−1/グルカゴン受容体コアゴニスト
|
|
MX382408B
(es)
|
2014-10-24 |
2025-03-13 |
Merck Sharp & Dohme Llc |
Coagonistas de los receptores de glucagón y de glp-1.
|
|
WO2016198624A1
(en)
|
2015-06-12 |
2016-12-15 |
Sanofi |
Exendin-4 derivatives as trigonal glp-1/glucagon/gip receptor agonists
|
|
WO2016198604A1
(en)
|
2015-06-12 |
2016-12-15 |
Sanofi |
Exendin-4 derivatives as dual glp-1 /glucagon receptor agonists
|
|
TW201706291A
(zh)
|
2015-07-10 |
2017-02-16 |
賽諾菲公司 |
作為選擇性肽雙重glp-1/升糖素受體促效劑之新毒蜥外泌肽(exendin-4)衍生物
|