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ES477785A1 - Procedimiento para la preparacion de nuevas 2-fenilimino- imidazolidinas sustituidas. - Google Patents

Procedimiento para la preparacion de nuevas 2-fenilimino- imidazolidinas sustituidas.

Info

Publication number
ES477785A1
ES477785A1 ES477785A ES477785A ES477785A1 ES 477785 A1 ES477785 A1 ES 477785A1 ES 477785 A ES477785 A ES 477785A ES 477785 A ES477785 A ES 477785A ES 477785 A1 ES477785 A1 ES 477785A1
Authority
ES
Spain
Prior art keywords
phenyl
methyl
chloro
salts
dichloro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES477785A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of ES477785A1 publication Critical patent/ES477785A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

2-fenilimino-imidazolidinas sustituidas de la fórmula general. **fórmula** en que R significa un radical 2,6-dicloro-4-hidroximatilfenilo, 2-cloro-4-metil-5-aminofenilo, 2-5-cloro-4-metil-fenilomino, 2-cloro -4-metil-5-5-nitrofenilo, 2-3-dicloro-4-metil.fenilo, 2 cloro-4-metil-6-nitrofenilo, 2-cloro-4-metil-6-aminofenilo, 2,4,6-trifluorofenilo, tetrafluorofenilo o 3-bromo-4-fluorofenilo, asi como sus sales por adición de ácido.
ES477785A 1978-02-17 1979-02-16 Procedimiento para la preparacion de nuevas 2-fenilimino- imidazolidinas sustituidas. Expired ES477785A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782806811 DE2806811A1 (de) 1978-02-17 1978-02-17 Neue substituierte 2-phenylimino- imidazolidine, deren saeureadditionssalze, diese enthaltene arzneimittel und verfahren zur herstellung derselben

Publications (1)

Publication Number Publication Date
ES477785A1 true ES477785A1 (es) 1980-02-01

Family

ID=6032262

Family Applications (1)

Application Number Title Priority Date Filing Date
ES477785A Expired ES477785A1 (es) 1978-02-17 1979-02-16 Procedimiento para la preparacion de nuevas 2-fenilimino- imidazolidinas sustituidas.

Country Status (11)

Country Link
US (1) US4213995A (es)
JP (1) JPS54122274A (es)
AU (1) AU519357B2 (es)
BE (1) BE874253A (es)
DE (1) DE2806811A1 (es)
DK (1) DK146066C (es)
ES (1) ES477785A1 (es)
FR (1) FR2417503A1 (es)
GB (1) GB2014983B (es)
IT (1) IT1114720B (es)
NL (1) NL7901242A (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4287201A (en) * 1980-03-03 1981-09-01 Merck & Co., Inc. Anovulatory method and chicken feed compositions
EP0043659B1 (en) * 1980-07-09 1985-02-06 Beecham Group Plc Clonidine derivatives useful in the treatment of diarrhoea
CA1201066A (en) * 1981-11-20 1986-02-25 Alcon Laboratories, Inc. N-¬3,5-dichloro-4-(2-imidazolidinylideneamino)- phenyl|-acetamide solutions for lowering intraocular pressure
US4515800A (en) * 1981-11-20 1985-05-07 Icilio Cavero Method of lowering intraocular pressure using phenylimino-imidazoles
US4461904A (en) * 1981-11-20 1984-07-24 Alcon Laboratories, Inc. 2-(Trisubstituted phenylimino)-imidazolines
US4517199A (en) * 1981-11-20 1985-05-14 Alcon Laboratories, Inc. Method for lowering intraocular pressure using phenylimino-imidazoles
US4644007A (en) * 1981-11-20 1987-02-17 Alcon Laboratories, Inc. 3-chloro-4-(4,5-dihydro-1H-imidazo-2-yl)-amino-5-alkylbenzoic acids, esters, salts, compositions and methods
US4587257A (en) * 1984-12-14 1986-05-06 Alcon Laboratories, Inc. Control of ocular bleeding using clonidine derivatives
DE19514579A1 (de) * 1995-04-20 1996-10-24 Boehringer Ingelheim Kg Verwendung von alpha¶1¶¶L¶-Agonisten zur Behandlung der Harninkontinenz
US6602897B2 (en) 2000-10-14 2003-08-05 Boehringer Ingelheim Pharma Kg m-Amino-phenylimino-imidazolidine derivatives for treating urinary incontinence
JP2004511547A (ja) * 2000-10-14 2004-04-15 ベーリンガー　インゲルハイム　ファルマ　ゲゼルシャフト　ミット　ベシュレンクテル　ハフツング　ウント　コンパニー　コマンディトゲゼルシャフト 尿失禁治療用の新規ｍ−アミノ−フェニルイミノ−イミダゾリジン誘導体

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE623305A (es) *
US3236857A (en) * 1961-10-09 1966-02-22 Boehringer Sohn Ingelheim 2-(phenyl-amino)-1, 3-diazacyclopentene-(2) substitution products
NL123037C (es) * 1963-10-04
US3595961A (en) * 1965-10-01 1971-07-27 Boehringer Sohn Ingelheim Hypotensive compositions containing 2-(2' - halo-anilino) - 1,3 -diazacyclopentenes-(2) and methods of using the same
BE687656A (es) * 1965-10-01 1967-03-30
DE1545628A1 (de) * 1965-10-01 1970-06-25 Boehringer Sohn Ingelheim Verfahren zur Herstellung von blutdrucksenkend und sedativ wirksamen Derivaten des 2-(2-Halogenanilino)-1,3-diazacyclopentens-(2)
DE1670274A1 (de) * 1966-10-31 1970-07-16 Boehringer Sohn Ingelheim Neues Verfahren zur Herstellung von 2-Arylamino-1,3-diazacycloalkenen-(2)
DE2356005A1 (de) * 1973-11-09 1975-05-22 Boehringer Sohn Ingelheim Neue 7-amino-imidazo eckige klammer auf 1,2-a eckige klammer zu pyrimidine, diese enthaltende arzneimittel sowie verfahren zu deren herstellung
DE2446758C3 (de) * 1974-10-01 1979-01-04 C.H. Boehringer Sohn, 6507 Ingelheim 2-(2-Fluor-6-trifluormethylphenylimino)-imidazolidin, dessen Säureadditionssalze, Verfahren zur Herstellung dieser Verbindungen und deren Verwendung bei der Bekämpfung der Hypertonie
DE2523103C3 (de) * 1975-05-24 1979-11-29 C.H. Boehringer Sohn, 6507 Ingelheim Substituierte 2-[N-Progargyl-N-(2-chlorphenyl)amino] -imidazoline-^), deren Säureadditionssalze, Verfahren zu ihrer Herstellung und deren Verwendung
DE2630060C2 (de) * 1976-07-03 1984-04-19 C.H. Boehringer Sohn, 6507 Ingelheim 2-(2-Brom-6-fluor-phenylimino)-imidazolidin, dessen Säureadditionssalze, diese enthaltende Arzneimittel und Verfahren zu deren Herstellung

Also Published As

Publication number Publication date
BE874253A (fr) 1979-08-16
GB2014983B (en) 1982-11-03
FR2417503A1 (fr) 1979-09-14
IT1114720B (it) 1986-01-27
AU4432679A (en) 1979-08-23
GB2014983A (en) 1979-09-05
AU519357B2 (en) 1981-11-26
IT7948011A0 (it) 1979-02-15
DK69179A (da) 1979-08-18
FR2417503B1 (es) 1980-10-10
DK146066C (da) 1983-11-14
DE2806811A1 (de) 1979-08-23
DK146066B (da) 1983-06-20
NL7901242A (nl) 1979-08-21
JPS54122274A (en) 1979-09-21
US4213995A (en) 1980-07-22

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971201