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ES8102561A1 - Procedimiento de preparacion de los aril-1 arilsulfonil-4 a amino-propoxi-3 1h pirazoles - Google Patents

Procedimiento de preparacion de los aril-1 arilsulfonil-4 a amino-propoxi-3 1h pirazoles

Info

Publication number
ES8102561A1
ES8102561A1 ES492986A ES492986A ES8102561A1 ES 8102561 A1 ES8102561 A1 ES 8102561A1 ES 492986 A ES492986 A ES 492986A ES 492986 A ES492986 A ES 492986A ES 8102561 A1 ES8102561 A1 ES 8102561A1
Authority
ES
Spain
Prior art keywords
hypocholesterolemiant
hypolipemiant
arylsulphonyl
aminopropoxy
pyrazoles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES492986A
Other languages
English (en)
Other versions
ES492986A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoire Roger Bellon SA
Original Assignee
Laboratoire Roger Bellon SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire Roger Bellon SA filed Critical Laboratoire Roger Bellon SA
Publication of ES492986A0 publication Critical patent/ES492986A0/es
Publication of ES8102561A1 publication Critical patent/ES8102561A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/28—Two oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO DE PREPARACION DE LOS ARIL-1 ARILSULFONIL-4 AMINO-PROPOXI-3 1H PIRAZOLES, DE FORMULA (I), EN DONDE R1, R2, R3, R4, R5 Y R6 REPRESENTAN DISTINTOS ATOMOS O RADICALES. SE CARACTERIZA POR TENER LUGAR LA CONDENSACION DE UN HALOGENO-1 DIALKIL-AMINO-3 PROPANO X-(CH2)3-NR5R6, DONDE X ES UN ATOMO DE HALOGENO, CON UNA SAL ALCALINA DE UN ARIL-1-ARILSULFONIL-4 1H-PIRAZOLOIL-3, A UNA TEMPERATURA DE 60 A 120GC, EN EL SENO DE UN DISOLVENTE ORGANICO. TIENE APLICACIONES TERAPEUTICAS. -
ES492986A 1979-07-05 1980-07-01 Procedimiento de preparacion de los aril-1 arilsulfonil-4 a amino-propoxi-3 1h pirazoles Expired ES8102561A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7917507A FR2460299A1 (fr) 1979-07-05 1979-07-05 Nouveaux derives du pyrazole et leur application therapeutique

Publications (2)

Publication Number Publication Date
ES492986A0 ES492986A0 (es) 1981-02-16
ES8102561A1 true ES8102561A1 (es) 1981-02-16

Family

ID=9227565

Family Applications (1)

Application Number Title Priority Date Filing Date
ES492986A Expired ES8102561A1 (es) 1979-07-05 1980-07-01 Procedimiento de preparacion de los aril-1 arilsulfonil-4 a amino-propoxi-3 1h pirazoles

Country Status (10)

Country Link
US (1) US4337263A (es)
JP (1) JPS5615271A (es)
BE (1) BE884189A (es)
CA (1) CA1152507A (es)
DE (1) DE3025579A1 (es)
ES (1) ES8102561A1 (es)
FR (1) FR2460299A1 (es)
GB (2) GB2063870B (es)
IT (1) IT8068062A0 (es)
NL (1) NL8003888A (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA857592B (en) * 1984-10-17 1986-05-28 Heumann Ludwig & Co Gmbh Pyrazole derivatives,processes for their preparation and pharmaceutical preparations containing these compounds
US4964895A (en) * 1987-06-08 1990-10-23 Monsanto Company Substituted 4-(4-nitrophenoxy) pyrazoles and their use as herbicides
US6103900A (en) * 1992-12-17 2000-08-15 Pfizer Inc Pyrazoles and pyrazolopyrimidines having CRF antagonistic activity
BR9307659A (pt) * 1992-12-17 1999-06-29 Pfizer Pirazóis e pirazolopirimidinas tendo atividade antagonista crf
US6005109A (en) * 1997-10-30 1999-12-21 Pflizer Inc. Pyrazoles and pyrazolopyrimidines having CRF antagonistic activity
US5646152A (en) * 1994-06-15 1997-07-08 Pfizer Inc. Methods of administering CRF antagonists
WO2006021462A1 (en) * 2004-08-27 2006-03-02 Laboratorios Del Dr. Esteve, S.A. Sigma receptor inhibitors
RU2417987C2 (ru) * 2004-08-27 2011-05-10 Лабораторьос Дель Др.Эстеве, С.А. Ингибиторы сигма-рецептора
EP1634872A1 (en) * 2004-08-27 2006-03-15 Laboratorios Del Dr. Esteve, S.A. Pyrazole derivatives as sigma receptor inhibitors
EP1829875A1 (en) 2006-03-01 2007-09-05 Laboratorios Del Dr. Esteve, S.A. Pyrazole derivatives as sigma receptor inhibitors
EP1994032A1 (en) * 2006-03-01 2008-11-26 Laboratorios del Dr. Esteve S.A. Pyrazole derivatives as sigma receptor inhibitors
EP1829866A1 (en) 2006-03-02 2007-09-05 Laboratorios Del Dr. Esteve, S.A. Sigma receptor inhibitors
EP1829867A1 (en) 2006-03-03 2007-09-05 Laboratorios Del Dr. Esteve, S.A. Imidazole compounds having pharmaceutical activity towards the sigma receptor
WO2009029317A2 (en) * 2007-06-08 2009-03-05 Georgia State University Research Foundation, Inc. Compositions for regulating or modulating quorum sensing in bacteria, methods of using the compounds, and methods of regulating or modulating quorum sensing in bacteria
EP2116539A1 (en) 2008-04-25 2009-11-11 Laboratorios Del. Dr. Esteve, S.A. 1-aryl-3-aminoalkoxy-pyrazoles as sigma ligands enhancing analgesic effects of opioids and attenuating the dependency thereof
EP2353591A1 (en) 2010-02-04 2011-08-10 Laboratorios Del. Dr. Esteve, S.A. Sigma ligands for potentiating the analgesic effect of opioids and opiates in post-operative pain and attenuating the dependency thereof
EP2388005A1 (en) 2010-05-21 2011-11-23 Laboratorios Del. Dr. Esteve, S.A. Sigma ligands for the prevention and/or treatment of emesis induced by chemotherapy or radiotherapy
EP2395003A1 (en) 2010-05-27 2011-12-14 Laboratorios Del. Dr. Esteve, S.A. Pyrazole compounds as sigma receptor inhibitors
EP2415471A1 (en) 2010-08-03 2012-02-08 Laboratorios Del. Dr. Esteve, S.A. Use of sigma ligands in opioid-induced hyperalgesia
EP2524694A1 (en) 2011-05-19 2012-11-21 Laboratorios Del. Dr. Esteve, S.A. Use of sigma ligands in diabetes type-2 associated pain
CA2933511A1 (en) 2013-12-17 2015-06-25 Laboratorios Del Dr. Esteve, S.A. Serotonin-norepinephrine reuptake inhibitors (snris) and sigma receptor ligands combinations

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI34517A (fi) 1962-12-08 1964-10-10 Laeaeketehdas Orion Oy 5-pyratsolyylialkamiinieetterien valmistusmenetelmä
JPS4832112B1 (es) * 1969-10-03 1973-10-04
DE2409753A1 (de) * 1974-03-01 1975-09-11 Basf Ag Substituierte pyrazole
FR2301250A1 (fr) 1975-02-21 1976-09-17 Bellon Labor Sa Roger Nouveaux diaryl-1, 4o-aminoalcoxy-3 pyrazoles et leurs sels

Also Published As

Publication number Publication date
IT8068062A0 (it) 1980-07-04
CA1152507A (fr) 1983-08-23
BE884189A (fr) 1981-01-05
GB2054566A (en) 1981-02-18
FR2460299B1 (es) 1983-01-14
GB2063870B (en) 1983-06-22
JPS5615271A (en) 1981-02-14
GB2054566B (en) 1983-05-18
ES492986A0 (es) 1981-02-16
FR2460299A1 (fr) 1981-01-23
NL8003888A (nl) 1981-01-07
US4337263A (en) 1982-06-29
DE3025579A1 (de) 1981-01-15
GB2063870A (en) 1981-06-10

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