DE60106933D1 - Verfahren zur herstellung von citalopram - Google Patents

Verfahren zur herstellung von citalopram

Info

Publication number: DE60106933D1
Authority: DE; Germany
Prior art keywords: citalopram; preparation
Prior art date: 2000-08-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE60106933T

Other languages

English (en)

Other versions

DE60106933T2 (de

Inventor

Hans Petersen

Haleh Ahmadian

Robert Dancer

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

H Lundbeck AS

Original Assignee

H Lundbeck AS

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-08-18

Filing date

2001-08-14

Publication date

2004-12-09

2001-08-14 Application filed by H Lundbeck AS filed Critical H Lundbeck AS

2004-12-09 Publication of DE60106933D1 publication Critical patent/DE60106933D1/de

2005-12-01 Application granted granted Critical

2005-12-01 Publication of DE60106933T2 publication Critical patent/DE60106933T2/de

2021-08-15 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Psychiatry (AREA)
Addiction (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)
Steroid Compounds (AREA)
Furan Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

DE60106933T 2000-08-18 2001-08-14 Verfahren zur herstellung von citalopram Expired - Lifetime DE60106933T2 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DK200001231		2000-08-18
DKPA200001231		2000-08-18
PCT/DK2001/000542 WO2002016342A1 (en)	2000-08-18	2001-08-14	Method for the preparation of citalopram

Publications (2)

Publication Number	Publication Date
DE60106933D1 true DE60106933D1 (de)	2004-12-09
DE60106933T2 DE60106933T2 (de)	2005-12-01

Family

ID=8159660

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
DE60106933T Expired - Lifetime DE60106933T2 (de)	2000-08-18	2001-08-14	Verfahren zur herstellung von citalopram
DE60106932T Expired - Lifetime DE60106932T2 (de)	2000-08-18	2001-08-14	Verfahren zur herstellung von citalopram
DE10140029A Withdrawn DE10140029A1 (de)	2000-08-18	2001-08-16	Vefahren zur Herstellung von Citalopram
DE10140028A Withdrawn DE10140028A1 (de)	2000-08-18	2001-08-16	Verfahren zur Herstellung von Citalopram

Family Applications After (3)

Application Number	Title	Priority Date	Filing Date
DE60106932T Expired - Lifetime DE60106932T2 (de)	2000-08-18	2001-08-14	Verfahren zur herstellung von citalopram
DE10140029A Withdrawn DE10140029A1 (de)	2000-08-18	2001-08-16	Vefahren zur Herstellung von Citalopram
DE10140028A Withdrawn DE10140028A1 (de)	2000-08-18	2001-08-16	Verfahren zur Herstellung von Citalopram

Country Status (41)

Country	Link
US (2)	US6426422B1 (de)
EP (2)	EP1309581B1 (de)
JP (2)	JP2004506730A (de)
KR (2)	KR100887206B1 (de)
CN (3)	CN1159307C (de)
AR (3)	AR029598A1 (de)
AT (4)	ATE281448T1 (de)
AU (6)	AU2001279609B2 (de)
BE (2)	BE1013443A6 (de)
BG (2)	BG65964B1 (de)
CA (2)	CA2354877C (de)
CH (2)	CH691968A5 (de)
CL (2)	CL2008002412A1 (de)
CZ (2)	CZ294746B6 (de)
DE (4)	DE60106933T2 (de)
DK (4)	DK200101219A (de)
EA (2)	EA005946B1 (de)
ES (4)	ES2228920T3 (de)
FI (2)	FI20011621L (de)
FR (2)	FR2813077B1 (de)
GB (2)	GB2362647B (de)
GR (1)	GR1004074B (de)
HK (2)	HK1044538B (de)
HR (2)	HRP20030065A2 (de)
HU (2)	HUP0103291A3 (de)
IE (2)	IES20010760A2 (de)
IL (2)	IL144816A (de)
IS (2)	IS2121B (de)
ME (2)	MEP2208A (de)
MX (2)	MXPA03001329A (de)
NL (2)	NL1018775C1 (de)
NO (2)	NO326570B1 (de)
NZ (2)	NZ523877A (de)
PL (2)	PL359969A1 (de)
PT (2)	PT1309581E (de)
RS (2)	RS50258B (de)
SI (2)	SI1309582T1 (de)
SK (2)	SK287236B6 (de)
UA (2)	UA72340C2 (de)
WO (2)	WO2002016341A1 (de)
ZA (1)	ZA200106683B (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR022329A1 (es)	1999-01-29	2002-09-04	Lundbeck & Co As H	Metodo para la preparacion de 5-cianoftalida
AU759716B2 (en)	1999-04-14	2003-04-17	H. Lundbeck A/S	Method for the preparation of citalopram
ITMI991581A1 (it) *	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
DE69920526T2 (de)	1999-10-25	2006-02-23	H. Lundbeck A/S	Verfahren zur herstellung von citalopram
AR026063A1 (es)	1999-11-01	2002-12-26	Lundbeck & Co As H	Metodo para la preparacion de 5-carboxiftalida.
PT1246812E (pt)	1999-12-28	2004-08-31	Lundbeck & Co As H	Metodo para a preparacao de citalopram
UA73336C2 (en)	1999-12-30	2005-07-15	Lundbeck & Co As H	A method for the preparation of 5-cyano-phtalid
ES2206177T3 (es) *	2000-01-14	2004-05-16	H. Lundbeck A/S	Metodo para la preparacion de 5-cianoftalida.
IES20010157A2 (en)	2000-03-03	2002-03-06	Lundbeck & Co As H	Method for the preparation of citalopram
WO2001068629A1 (en) *	2000-03-13	2001-09-20	H. Lundbeck A/S	Stepwise alkylation of 5-substituted 1-(4-fluorophenyl)-1,3-dihydroisobenzofurans
IL151490A0 (en) *	2000-03-13	2003-04-10	Lundbeck & Co As H	Method for the preparation of citalopram
NL1017500C1 (nl)	2000-03-13	2001-04-26	Lundbeck & Co As H	Werkwijze voor de bereiding van Citalopram.
DE60101786T2 (de)	2000-03-14	2004-07-15	H. Lundbeck A/S, Valby	Verfahren zur herstellung von citalopram
PL360115A1 (en) *	2000-03-16	2004-09-06	H.Lundbeck A/S	Method for the preparation of 5-cyano-1-(4-fluorophenyl)-1,3-dihydroisobenzofurans
AR032455A1 (es)	2000-05-12	2003-11-12	Lundbeck & Co As H	Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
IL144816A (en)	2000-08-18	2005-09-25	Lundbeck & Co As H	Method for the preparation of citalopram
IL147226A (en)	2000-12-22	2006-04-10	Lundbeck & Co As H	Process for the preparation of pure citalopram
US7148364B2 (en) *	2002-01-07	2006-12-12	Sun Pharmaceutical Industries	Process for the preparation of 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofuran carbonitrile
PE20040991A1 (es) *	2002-08-12	2004-12-27	Lundbeck & Co As H	Separacion de intermediarios para la preparacion de escitalopram
AU2003223105A1 (en) *	2003-03-24	2004-10-18	Hetero Drugs Limited	Novel crystalline forms of (s)-citalopram oxalate
US20050143350A1 (en) *	2003-11-19	2005-06-30	Seed John C.	Combination drug therapy to treat obesity
CN100569765C (zh)	2003-12-19	2009-12-16	杭州民生药业集团有限公司	西酞普兰中间体晶体碱
WO2009111031A2 (en) *	2008-03-04	2009-09-11	Intra-Cellular Therapies, Inc.	Methods of treating vasomotor symptoms
US20100087664A1 (en) *	2008-10-07	2010-04-08	Ravindra Vedantham	Preparation of citalopram and salts thereof
JP6222973B2 (ja) *	2013-04-19	2017-11-01	日本テルペン化学株式会社	ジベンジルトリチオカーボネート誘導体
CN103936702A (zh) *	2014-05-07	2014-07-23	成都诺维尔生物医药有限公司	艾司西酞普兰杂质j的合成方法
US9809524B1 (en) *	2014-10-14	2017-11-07	Syngenta Participations	Process for the preparation of 1-(3,5-dichloro-4-fluoro-phenyl)-2,2,2-trifluoro-ethanone
CN118724848A (zh) *	2023-03-29	2024-10-01	中国石油化工股份有限公司	一种制备2,5-呋喃二甲腈的方法

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1143702A (de)	1965-03-18
GB1526331A (en) *	1976-01-14	1978-09-27	Kefalas As	Phthalanes
GB8419963D0 (en)	1984-08-06	1984-09-12	Lundbeck & Co As H	Intermediate compound and method
GB8814057D0 (en)	1988-06-14	1988-07-20	Lundbeck & Co As H	New enantiomers & their isolation
DE3926765A1 (de)	1989-08-12	1991-02-14	Hoechst Ag	Verfahren zur verminderung von primaerem und sekundaerem amin in einem tertiaeren amin
US5296507A (en)	1990-09-06	1994-03-22	H.Lundbeck A/S	Treatment of cerbrovascular disorders
DK213290D0 (da)	1990-09-06	1990-09-06	Lundbeck & Co As H	Treatment of cerebrovascular disorders
DE19626659A1 (de)	1996-07-03	1998-01-08	Basf Ag	Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de)	1996-07-10	1998-01-15	Basf Ag	Verfahren zur Herstellung von Phthaliden
ZA9711376B (en)	1996-12-20	1998-07-21	Lundbeck & Co As H	Indole or dihydroindole derivatives
EA001728B1 (ru)	1997-07-08	2001-08-27	Х.Лундбекк А/С	Способ получения циталопрама
UA62985C2 (en) *	1997-11-10	2004-01-15	Lunnbeck As H	A method for the preparation of citalopram
CZ292911B6 (cs)	1997-11-11	2004-01-14	H. Lundbeck A/S	Způsob výroby citalopramu
NZ510858A (en) *	1998-10-20	2003-11-28	H	Method for the preparation of citalopram
TR200101796T2 (tr) *	1998-12-23	2001-11-21	H. Lundbeck A/S	5-Siyanofitalitin preparasyonuna yönelik metot
AR022329A1 (es)	1999-01-29	2002-09-04	Lundbeck & Co As H	Metodo para la preparacion de 5-cianoftalida
AU759716B2 (en)	1999-04-14	2003-04-17	H. Lundbeck A/S	Method for the preparation of citalopram
ITMI991581A1 (it) *	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
ITMI991579A1 (it) *	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
EP1228056B1 (de)	1999-10-25	2004-09-22	H. Lundbeck A/S	Verfahren zur herstellung von citalopram
US6310222B1 (en)	1999-11-01	2001-10-30	Sumika Fine Chemicals Co., Ltd.	Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
FR2805812A1 (fr)	2000-02-24	2001-09-07	Lundbeck & Co As H	Procede de preparation du citalopram
IES20010143A2 (en)	2000-02-24	2001-07-25	Lundbeck & Co As H	Method for the preparation of citalopram
GB0005477D0 (en) *	2000-03-07	2000-04-26	Resolution Chemicals Limited	Process for the preparation of citalopram
IL144816A (en)	2000-08-18	2005-09-25	Lundbeck & Co As H	Method for the preparation of citalopram
IL147226A (en)	2000-12-22	2006-04-10	Lundbeck & Co As H	Process for the preparation of pure citalopram
PL353369A1 (en)	2000-12-28	2003-11-17	H.Lundbeck A/S	Process for the preparation of pure citalopram

2001
- 2001-08-09 IL IL14481601A patent/IL144816A/xx not_active IP Right Cessation
- 2001-08-09 FI FI20011621A patent/FI20011621L/fi unknown
- 2001-08-09 FI FI20011622A patent/FI20011622L/fi unknown
- 2001-08-09 CA CA002354877A patent/CA2354877C/en not_active Expired - Fee Related
- 2001-08-09 CA CA002354880A patent/CA2354880C/en not_active Expired - Fee Related
- 2001-08-09 IL IL14481701A patent/IL144817A0/xx not_active IP Right Cessation
- 2001-08-10 IS IS6048A patent/IS2121B/is unknown
- 2001-08-10 IS IS6047A patent/IS2120B/is unknown
- 2001-08-10 HU HU0103291A patent/HUP0103291A3/hu unknown
- 2001-08-13 IE IE20010760A patent/IES20010760A2/en not_active IP Right Cessation
- 2001-08-13 IE IE20010761A patent/IES20010761A2/en not_active IP Right Cessation
- 2001-08-13 HU HU0103295A patent/HUP0103295A3/hu unknown
- 2001-08-14 AU AU2001279609A patent/AU2001279609B2/en not_active Ceased
- 2001-08-14 PT PT01957785T patent/PT1309581E/pt unknown
- 2001-08-14 EP EP01957785A patent/EP1309581B1/de not_active Expired - Lifetime
- 2001-08-14 EA EA200300279A patent/EA005946B1/ru not_active IP Right Cessation
- 2001-08-14 AU AU7960801A patent/AU7960801A/xx active Pending
- 2001-08-14 ME MEP-22/08A patent/MEP2208A/xx unknown
- 2001-08-14 DE DE60106933T patent/DE60106933T2/de not_active Expired - Lifetime
- 2001-08-14 AU AU2001279608A patent/AU2001279608B2/en not_active Ceased
- 2001-08-14 RS YU6903A patent/RS50258B/sr unknown
- 2001-08-14 NO NO20013943A patent/NO326570B1/no not_active IP Right Cessation
- 2001-08-14 AU AU7960901A patent/AU7960901A/xx active Pending
- 2001-08-14 NZ NZ523877A patent/NZ523877A/en unknown
- 2001-08-14 DK DK200101219A patent/DK200101219A/da not_active Application Discontinuation
- 2001-08-14 AT AT01957786T patent/ATE281448T1/de not_active IP Right Cessation
- 2001-08-14 DK DK200101216A patent/DK200101216A/da not_active Application Discontinuation
- 2001-08-14 RS YUP-115/03A patent/RS50287B/sr unknown
- 2001-08-14 AT AT01957785T patent/ATE281447T1/de not_active IP Right Cessation
- 2001-08-14 EP EP01957786A patent/EP1309582B1/de not_active Expired - Lifetime
- 2001-08-14 NZ NZ523853A patent/NZ523853A/en unknown
- 2001-08-14 DE DE60106932T patent/DE60106932T2/de not_active Expired - Lifetime
- 2001-08-14 HR HR20030065A patent/HRP20030065A2/xx not_active Application Discontinuation
- 2001-08-14 SI SI200130272T patent/SI1309582T1/xx unknown
- 2001-08-14 WO PCT/DK2001/000541 patent/WO2002016341A1/en not_active Ceased
- 2001-08-14 KR KR1020037002005A patent/KR100887206B1/ko not_active Expired - Fee Related
- 2001-08-14 HR HR20030064A patent/HRP20030064A2/xx not_active Application Discontinuation
- 2001-08-14 MX MXPA03001329A patent/MXPA03001329A/es active IP Right Grant
- 2001-08-14 PT PT01957786T patent/PT1309582E/pt unknown
- 2001-08-14 DK DK01957785T patent/DK1309581T3/da active
- 2001-08-14 PL PL35996901A patent/PL359969A1/xx not_active Application Discontinuation
- 2001-08-14 NO NO20013942A patent/NO326772B1/no not_active IP Right Cessation
- 2001-08-14 GB GB0119733A patent/GB2362647B/en not_active Expired - Fee Related
- 2001-08-14 PL PL35982501A patent/PL359825A1/xx not_active Application Discontinuation
- 2001-08-14 WO PCT/DK2001/000542 patent/WO2002016342A1/en not_active Ceased
- 2001-08-14 JP JP2002521443A patent/JP2004506730A/ja not_active Withdrawn
- 2001-08-14 UA UA2003010797A patent/UA72340C2/uk unknown
- 2001-08-14 ME MEP-23/08A patent/MEP2308A/xx unknown
- 2001-08-14 GR GR20010100398A patent/GR1004074B/el unknown
- 2001-08-14 GB GB0119734A patent/GB2365865B/en not_active Expired - Fee Related
- 2001-08-14 UA UA2003010798A patent/UA71676C2/uk unknown
- 2001-08-14 US US09/930,107 patent/US6426422B1/en not_active Expired - Fee Related
- 2001-08-14 SI SI200130273T patent/SI1309581T1/xx unknown
- 2001-08-14 DK DK01957786T patent/DK1309582T3/da active
- 2001-08-14 JP JP2002521442A patent/JP2004506729A/ja not_active Withdrawn
- 2001-08-14 US US09/930,110 patent/US6509483B2/en not_active Expired - Fee Related
- 2001-08-14 ES ES01957786T patent/ES2228920T3/es not_active Expired - Lifetime
- 2001-08-14 ES ES01957785T patent/ES2230347T3/es not_active Expired - Lifetime
- 2001-08-14 MX MXPA03000913A patent/MXPA03000913A/es active IP Right Grant
- 2001-08-14 KR KR1020037001900A patent/KR100887207B1/ko not_active Expired - Fee Related
- 2001-08-14 SK SK320-2003A patent/SK287236B6/sk not_active IP Right Cessation
- 2001-08-14 SK SK322-2003A patent/SK287008B6/sk not_active IP Right Cessation
- 2001-08-14 EA EA200300277A patent/EA005811B1/ru not_active IP Right Cessation
- 2001-08-14 ZA ZA200106683A patent/ZA200106683B/xx unknown
- 2001-08-15 CZ CZ20012958A patent/CZ294746B6/cs not_active IP Right Cessation
- 2001-08-15 CZ CZ20012959A patent/CZ295863B6/cs not_active IP Right Cessation
- 2001-08-15 AU AU2001100271A patent/AU2001100271B4/en not_active Expired
- 2001-08-16 DE DE10140029A patent/DE10140029A1/de not_active Withdrawn
- 2001-08-16 DE DE10140028A patent/DE10140028A1/de not_active Withdrawn
- 2001-08-16 FR FR0110855A patent/FR2813077B1/fr not_active Expired - Fee Related
- 2001-08-16 CH CH01521/01A patent/CH691968A5/de not_active IP Right Cessation
- 2001-08-16 BE BE2001/0548A patent/BE1013443A6/fr not_active IP Right Cessation
- 2001-08-16 AR ARP010103924A patent/AR029598A1/es not_active Application Discontinuation
- 2001-08-16 NL NL1018775A patent/NL1018775C1/nl not_active IP Right Cessation
- 2001-08-16 AU AU2001100278A patent/AU2001100278B4/en not_active Expired
- 2001-08-16 FR FR0110857A patent/FR2813078B1/fr not_active Expired - Fee Related
- 2001-08-16 NL NL1018776A patent/NL1018776C1/nl not_active IP Right Cessation
- 2001-08-16 AR ARP010103923A patent/AR029597A1/es not_active Application Discontinuation
- 2001-08-16 CH CH01522/01A patent/CH691969A5/de not_active IP Right Cessation
- 2001-08-17 ES ES200101920A patent/ES2170735B2/es not_active Expired - Fee Related
- 2001-08-17 CN CNB011339470A patent/CN1159307C/zh not_active Expired - Fee Related
- 2001-08-17 AT AT0065101U patent/AT5026U1/de not_active IP Right Cessation
- 2001-08-17 ES ES200101919A patent/ES2170734B2/es not_active Expired - Fee Related
- 2001-08-17 CN CNB2004100018711A patent/CN1239490C/zh not_active Expired - Fee Related
- 2001-08-17 CN CNB011339489A patent/CN1222517C/zh not_active Expired - Fee Related
- 2001-08-17 AT AT0065001U patent/AT4946U1/de not_active IP Right Cessation
- 2001-08-20 BE BE2001/0550A patent/BE1013444A6/fr not_active IP Right Cessation
2002
- 2002-08-22 HK HK02106176.1A patent/HK1044538B/zh not_active IP Right Cessation
- 2002-09-04 HK HK02106522.2A patent/HK1047086B/zh not_active IP Right Cessation
2003
- 2003-02-24 BG BG107583A patent/BG65964B1/bg unknown
- 2003-02-24 BG BG107584A patent/BG65965B1/bg unknown
2008
- 2008-04-25 AR ARP080101772A patent/AR066694A2/es unknown
- 2008-08-14 CL CL2008002412A patent/CL2008002412A1/es unknown
- 2008-09-09 CL CL2008002673A patent/CL2008002673A1/es unknown

Also Published As

Publication number	Publication date
FR2813078A1 (fr)	2002-02-22
CN1515564A (zh)	2004-07-28
EP1309582B1 (de)	2004-11-03
FI20011622A7 (fi)	2002-02-19
AR029597A1 (es)	2003-07-10
SI1309581T1 (en)	2005-04-30
US6509483B2 (en)	2003-01-21
US6426422B1 (en)	2002-07-30
CN1339435A (zh)	2002-03-13
ES2230347T3 (es)	2005-05-01
NO20013942L (no)	2002-02-19
SK3222003A3 (en)	2003-08-05
BE1013444A6 (fr)	2002-01-15
EA200300277A1 (ru)	2003-08-28
DE60106932D1 (de)	2004-12-09
AT4946U1 (de)	2002-01-25
AR066694A2 (es)	2009-09-09
GB2362647B (en)	2002-09-18
BG107584A (bg)	2004-01-30
BG65965B1 (bg)	2010-07-30
CL2008002412A1 (es)	2009-01-02
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GB0119733D0 (en)	2001-10-03
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HK1068069A1 (en)	2005-04-22
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EP1309581A1 (de)	2003-05-14
JP2004506730A (ja)	2004-03-04
CA2354877C (en)	2006-05-02
ES2228920T3 (es)	2005-04-16
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CZ295863B6 (cs)	2005-11-16
KR100887207B1 (ko)	2009-03-06
EA005946B1 (ru)	2005-08-25
BG65964B1 (bg)	2010-07-30
DE10140029A1 (de)	2002-05-02
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SI1309582T1 (en)	2005-06-30
DE60106932T2 (de)	2005-11-03
EP1309581B1 (de)	2004-11-03
YU11503A (sh)	2006-05-25
CN1159307C (zh)	2004-07-28
NL1018775C1 (nl)	2001-10-24
RS50258B (sr)	2009-07-15
UA71676C2 (en)	2004-12-15
HUP0103291A2 (hu)	2002-05-29
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NO20013943L (no)	2002-02-19
AU7960901A (en)	2002-03-04
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MEP2308A (xx)	2010-02-10
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SK287236B6 (sk)	2010-04-07
EA005811B1 (ru)	2005-06-30
IS6047A (is)	2001-10-20
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ES2170734A1 (es)	2002-08-01
SK287008B6 (sk)	2009-09-07
ES2170735A1 (es)	2002-08-01
FI20011622L (fi)	2002-02-19
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AU7960801A (en)	2002-03-04
FR2813077A1 (fr)	2002-02-22
UA72340C2 (uk)	2005-02-15
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FI20011621A0 (fi)	2001-08-09
CH691968A5 (de)	2001-12-14
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ATE281448T1 (de)	2004-11-15
WO2002016341A1 (en)	2002-02-28
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HUP0103291A3 (en)	2003-02-28
BE1013443A6 (fr)	2002-01-15
IES20010761A2 (en)	2002-02-20
ZA200106683B (en)	2002-08-05
DE60106933T2 (de)	2005-12-01
FI20011621L (fi)	2002-02-19
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AU2001279609B2 (en)	2007-09-06
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ATE281447T1 (de)	2004-11-15
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NO326772B1 (no)	2009-02-16
PT1309582E (pt)	2005-03-31
CN1239490C (zh)	2006-02-01
IS2121B (is)	2006-06-15
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IL144816A0 (en)	2002-06-30
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GB0119734D0 (en)	2001-10-03
KR20030022378A (ko)	2003-03-15
PT1309581E (pt)	2005-03-31
MEP2208A (xx)	2010-02-10
AU2001279608B2 (en)	2006-10-05
AU2001100278A4 (en)	2001-09-13
CN1222517C (zh)	2005-10-12
KR20030022385A (ko)	2003-03-15
EP1309582A1 (de)	2003-05-14
HRP20030064A2 (en)	2005-02-28
ES2170735B2 (es)	2003-09-16

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