DE19983486T1 - Verfahren zur Herstellung von Citalopram - Google Patents

Verfahren zur Herstellung von Citalopram

Info

Publication number: DE19983486T1
Authority: DE; Germany
Prior art keywords: citalopram; preparation
Prior art date: 1999-06-25
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

DE19983486T

Other languages

English (en)

Other versions

DE19983486C2 (de

Inventor

Hans Petersen

Michael H Rock

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

H Lundbeck AS

Original Assignee

H Lundbeck AS

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-06-25

Filing date

1999-11-19

Publication date

2001-10-18

1999-11-19 Application filed by H Lundbeck AS filed Critical H Lundbeck AS

2001-10-18 Publication of DE19983486T1 publication Critical patent/DE19983486T1/de

2002-09-05 Application granted granted Critical

2002-09-05 Publication of DE19983486C2 publication Critical patent/DE19983486C2/de

2019-11-20 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- B01J31/22—Organic complexes
- B01J31/2282—Unsaturated compounds used as ligands
- B01J31/2295—Cyclic compounds, e.g. cyclopentadienyls
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- B01J31/24—Phosphines, i.e. phosphorus bonded to only carbon atoms, or to both carbon and hydrogen atoms, including e.g. sp2-hybridised phosphorus compounds such as phosphabenzene, phosphole or anionic phospholide ligands
- B01J31/2404—Cyclic ligands, including e.g. non-condensed polycyclic ligands, the phosphine-P atom being a ring member or a substituent on the ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2231/00—Catalytic reactions performed with catalysts classified in B01J31/00
- B01J2231/40—Substitution reactions at carbon centres, e.g. C-C or C-X, i.e. carbon-hetero atom, cross-coupling, C-H activation or ring-opening reactions
- B01J2231/42—Catalytic cross-coupling, i.e. connection of previously not connected C-atoms or C- and X-atoms without rearrangement
- B01J2231/4205—C-C cross-coupling, e.g. metal catalyzed or Friedel-Crafts type
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/80—Complexes comprising metals of Group VIII as the central metal
- B01J2531/84—Metals of the iron group
- B01J2531/847—Nickel

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Inorganic Chemistry (AREA)
Materials Engineering (AREA)
Neurosurgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Rheumatology (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Steroid Compounds (AREA)
Furan Compounds (AREA)

DE19983486T 1999-06-25 1999-11-19 Verfahren zur Herstellung von Citalopram Expired - Fee Related DE19983486C2 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DKPA199900921		1999-06-25
PCT/DK1999/000643 WO2000011926A2 (en)	1999-06-25	1999-11-19	Method for the preparation of citalopram

Publications (2)

Publication Number	Publication Date
DE19983486T1 true DE19983486T1 (de)	2001-10-18
DE19983486C2 DE19983486C2 (de)	2002-09-05

Family

ID=8099044

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DE19983486T Expired - Fee Related DE19983486C2 (de)	1999-06-25	1999-11-19	Verfahren zur Herstellung von Citalopram
DE69900891T Expired - Lifetime DE69900891D1 (de)	1999-06-25	1999-11-19	Verfahren zur herstellung von citalopram

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DE69900891T Expired - Lifetime DE69900891D1 (de)	1999-06-25	1999-11-19	Verfahren zur herstellung von citalopram

Country Status (36)

Country	Link
US (1)	US6750358B2 (de)
EP (1)	EP1105382B1 (de)
JP (1)	JP3389571B2 (de)
KR (1)	KR100491369B1 (de)
CN (1)	CN1129593C (de)
AR (1)	AR020573A1 (de)
AT (3)	ATE213237T1 (de)
AU (2)	AU2001100433B4 (de)
BG (1)	BG106190A (de)
BR (1)	BR9917367A (de)
CA (1)	CA2290125C (de)
CH (1)	CH691304A5 (de)
CZ (1)	CZ292174B6 (de)
DE (2)	DE19983486C2 (de)
DK (1)	DK1105382T3 (de)
EA (1)	EA002661B1 (de)
ES (1)	ES2172356T3 (de)
FI (1)	FI108538B (de)
GB (1)	GB2354240B (de)
HK (1)	HK1047745B (de)
HU (1)	HUP0103417A3 (de)
IL (1)	IL145960A0 (de)
IS (1)	IS5862A (de)
IT (1)	ITMI991579A1 (de)
MX (1)	MXPA01010986A (de)
NO (1)	NO20010318L (de)
NZ (1)	NZ514982A (de)
PL (1)	PL345971A1 (de)
PT (1)	PT1105382E (de)
SE (1)	SE516689C2 (de)
SI (1)	SI1105382T1 (de)
SK (1)	SK18412001A3 (de)
TR (1)	TR200103700T2 (de)
UA (1)	UA62023C2 (de)
WO (1)	WO2000011926A2 (de)
ZA (1)	ZA200108855B (de)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1140886B1 (de)	1998-12-23	2003-04-02	H. Lundbeck A/S	Verfahren zur herstellung von 5-cyanophthalid
AR022329A1 (es)	1999-01-29	2002-09-04	Lundbeck & Co As H	Metodo para la preparacion de 5-cianoftalida
KR100604156B1 (ko)	1999-04-14	2006-07-25	하. 룬트벡 아크티에 셀스카브	시탈로프람의 제조방법
ITMI991581A1 (it) *	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
ITMI991579A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
EP1228056B1 (de)	1999-10-25	2004-09-22	H. Lundbeck A/S	Verfahren zur herstellung von citalopram
HK1043129B (zh)	1999-10-25	2004-10-21	H‧隆德贝克有限公司	西酞普蘭的製備方法
AR026063A1 (es)	1999-11-01	2002-12-26	Lundbeck & Co As H	Metodo para la preparacion de 5-carboxiftalida.
CN1398263A (zh)	1999-12-28	2003-02-19	H·隆德贝克有限公司	制备西酞普兰的方法
HK1052512B (zh)	1999-12-30	2006-03-03	H. 隆德贝克有限公司	西酞普兰的制备方法
PL197821B1 (pl)	2000-01-14	2008-04-30	Lundbeck & Co As H	Sposób wytwarzania 5-cyjanoftalidu
NL1017415C1 (nl)	2000-02-24	2001-05-18	Lundbeck & Co As H	Werkwijze voor de bereiding van Citalopram.
NL1017417C1 (nl)	2000-03-03	2001-03-16	Lundbeck & Co As H	Werkwijze voor de bereiding van Citalopram.
GB0005477D0 (en)	2000-03-07	2000-04-26	Resolution Chemicals Limited	Process for the preparation of citalopram
NZ521204A (en) *	2000-03-13	2004-03-26	H	Stepwise alkylation of 5-substituted 1-(4-fluorophenyl)- 1,3-dihydroisobenzofurans for preparing citalopram, an anti depressant
TR200202166T2 (tr)	2000-03-13	2002-12-23	H. Lndbeck A/S	Sitalopramın preparasyon metodu
NL1017500C1 (nl)	2000-03-13	2001-04-26	Lundbeck & Co As H	Werkwijze voor de bereiding van Citalopram.
GB2357762B (en) *	2000-03-13	2002-01-30	Lundbeck & Co As H	Crystalline base of citalopram
PT1265882E (pt)	2000-03-14	2004-06-30	Lundbeck & Co As H	Metodo para preparacao de citalopram; composto e citalopram
HUP0300134A2 (en) *	2000-03-16	2003-05-28	Lundbeck & Co As H	Method for the preparation of 5-cyano-1-(4-fluorophenyl)-1,3-dihydroisobenzofurans
AR032455A1 (es)	2000-05-12	2003-11-12	Lundbeck & Co As H	Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
EA200200332A1 (ru) *	2000-07-06	2002-06-27	Х.Лундбекк А/С	Способ получения циталопрама
IL144817A0 (en) *	2000-08-18	2002-06-30	Lundbeck & Co As H	Method for the preparation of citalopram
IL147226A (en) *	2000-12-22	2006-04-10	Lundbeck & Co As H	Process for the preparation of pure citalopram
SK284418B6 (sk) *	2000-12-28	2005-04-01	H. Lundbeck A/S	Spôsob výroby citalopramu
EP1355897A1 (de)	2001-01-30	2003-10-29	Orion Corporation Fermion	Verfahren zur herstellung von 1-(3-dimethylaminopropyl)-1-(4-fluorphenyl)-1,3-dihydrobenzofuran-5-carbonitrile
GB0105627D0 (en) *	2001-03-07	2001-04-25	Cipla Ltd	Preparation of phthalanes
CZ20032567A3 (en) *	2001-03-09	2004-04-14	Ranbaxy Laboratories Limited	Process for the preparation of citalopram
WO2003011278A1 (en) *	2001-07-31	2003-02-13	H. Lundbeck A/S	Crystalline composition containing escitalopram
AU2003222435A1 (en)	2002-01-07	2003-07-24	Sun Pharmaceutical Industries Limited	Process for the preparation of 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)- 1,3-dihydro-5-isobenzofuran carbonitrile
TWI306846B (en)	2002-08-12	2009-03-01	Lundbeck & Co As H	Method for the separation of intermediates which may be used for the preparation of escitalopram
AU2003223105A1 (en) *	2003-03-24	2004-10-18	Hetero Drugs Limited	Novel crystalline forms of (s)-citalopram oxalate
US7019153B2 (en)	2003-06-10	2006-03-28	Sun Pharmaceutical Industries Limited	Process for hydrogenolysis of [1-(3-dimethylamino)propyl)]-1-(4-fluorophenyl)-1,3-dihydro-5-halo-isobenzofuran acetamido-3-substituted-3-cephem-4-carboxylic acid
TWI339651B (en)	2004-02-12	2011-04-01	Lundbeck & Co As H	Method for the separation of intermediates which may be used for the preparation of escitalopram
JP2006008603A (ja) *	2004-06-25	2006-01-12	Sumitomo Chemical Co Ltd	光学活性シタロプラムの製造方法、その中間体およびその製造方法
EP1797060A2 (de)	2004-08-23	2007-06-20	Sun Pharmaceutical Industries Limited	Verfahren zur herstellung von citalopram und enantiomeren
WO2006103550A1 (en) *	2005-03-31	2006-10-05	Ranbaxy Laboratories Limited	Processes for the preparation of citalopram and its intermediate 5-aminophthalide
TWI358407B (en)	2005-06-22	2012-02-21	Lundbeck & Co As H	Crystalline base of escitalopram and orodispersibl
US7834201B2 (en)	2005-06-22	2010-11-16	H. Lundbeck A/S	Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
EP2017271A1 (de)	2007-07-06	2009-01-21	Aurobindo Pharma Limited	Verfahren zur Herstellung von Escitalopram

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Publication number	Priority date	Publication date	Assignee	Title
GB1143703A (de)	1965-03-18
GB1526331A (en) *	1976-01-14	1978-09-27	Kefalas As	Phthalanes
GB8419963D0 (en)	1984-08-06	1984-09-12	Lundbeck & Co As H	Intermediate compound and method
GB8814057D0 (en)	1988-06-14	1988-07-20	Lundbeck & Co As H	New enantiomers & their isolation
CA2010159A1 (en)	1989-02-21	1990-08-21	James J. Maul	Cyanation of haloaromatics utilizing catalysts generated in situ starting with nic1 or nic1 6h 0
US5296507A (en)	1990-09-06	1994-03-22	H.Lundbeck A/S	Treatment of cerbrovascular disorders
DE19626659A1 (de)	1996-07-03	1998-01-08	Basf Ag	Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de)	1996-07-10	1998-01-15	Basf Ag	Verfahren zur Herstellung von Phthaliden
DE19706648A1 (de)	1997-02-20	1998-08-27	Bayer Ag	Verfahren zur Herstellung von aromatischen Nitrilen
SK283309B6 (sk)	1997-07-08	2003-05-02	H. Lundbeck A/S	Spôsob výroby citalopramu a medziprodukty
UA62985C2 (en)	1997-11-10	2004-01-15	Lunnbeck As H	A method for the preparation of citalopram
ES2149734T3 (es)	1997-11-11	2003-02-16	Lundbeck & Co As H	Metodo para la preparacion de citalopram.
WO2000023431A1 (en)	1998-10-20	2000-04-27	H. Lundbeck A/S	Method for the preparation of citalopram
EP1140886B1 (de)	1998-12-23	2003-04-02	H. Lundbeck A/S	Verfahren zur herstellung von 5-cyanophthalid
AR022329A1 (es)	1999-01-29	2002-09-04	Lundbeck & Co As H	Metodo para la preparacion de 5-cianoftalida
DE10015280A1 (de)	1999-03-29	2001-01-04	Nissan Chemical Ind Ltd	Verfahren zur Herstellung von Benzonitrilverbindungen
KR100604156B1 (ko)	1999-04-14	2006-07-25	하. 룬트벡 아크티에 셀스카브	시탈로프람의 제조방법
ITMI991581A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
ITMI991579A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
EP1228056B1 (de)	1999-10-25	2004-09-22	H. Lundbeck A/S	Verfahren zur herstellung von citalopram
US6310222B1 (en)	1999-11-01	2001-10-30	Sumika Fine Chemicals Co., Ltd.	Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
GB0005477D0 (en)	2000-03-07	2000-04-26	Resolution Chemicals Limited	Process for the preparation of citalopram
IL147226A (en)	2000-12-22	2006-04-10	Lundbeck & Co As H	Process for the preparation of pure citalopram
SK284418B6 (sk)	2000-12-28	2005-04-01	H. Lundbeck A/S	Spôsob výroby citalopramu

1999
- 1999-07-15 IT IT1999MI001579A patent/ITMI991579A1/it unknown
- 1999-11-19 NZ NZ514982A patent/NZ514982A/xx unknown
- 1999-11-19 ES ES99968206T patent/ES2172356T3/es not_active Expired - Lifetime
- 1999-11-19 DE DE19983486T patent/DE19983486C2/de not_active Expired - Fee Related
- 1999-11-19 DK DK99968206T patent/DK1105382T3/da active
- 1999-11-19 GB GB0101508A patent/GB2354240B/en not_active Expired - Fee Related
- 1999-11-19 TR TR2001/03700T patent/TR200103700T2/xx unknown
- 1999-11-19 CN CN99816768A patent/CN1129593C/zh not_active Expired - Fee Related
- 1999-11-19 IL IL14596099A patent/IL145960A0/xx unknown
- 1999-11-19 MX MXPA01010986A patent/MXPA01010986A/es not_active IP Right Cessation
- 1999-11-19 AU AU2001100433A patent/AU2001100433B4/en not_active Ceased
- 1999-11-19 KR KR10-2001-7013971A patent/KR100491369B1/ko not_active Expired - Fee Related
- 1999-11-19 HK HK02109330.8A patent/HK1047745B/zh not_active IP Right Cessation
- 1999-11-19 SI SI9930039T patent/SI1105382T1/xx unknown
- 1999-11-19 AT AT99968206T patent/ATE213237T1/de not_active IP Right Cessation
- 1999-11-19 BR BR9917367-0A patent/BR9917367A/pt not_active IP Right Cessation
- 1999-11-19 AT AT0904099A patent/AT409960B/de not_active IP Right Cessation
- 1999-11-19 WO PCT/DK1999/000643 patent/WO2000011926A2/en not_active Ceased
- 1999-11-19 HU HU0103417A patent/HUP0103417A3/hu unknown
- 1999-11-19 AU AU13748/00A patent/AU1374800A/en active Pending
- 1999-11-19 PL PL99345971A patent/PL345971A1/xx not_active Application Discontinuation
- 1999-11-19 CZ CZ2001319A patent/CZ292174B6/cs not_active IP Right Cessation
- 1999-11-19 EA EA200101071A patent/EA002661B1/ru not_active IP Right Cessation
- 1999-11-19 PT PT99968206T patent/PT1105382E/pt unknown
- 1999-11-19 UA UA2001117897A patent/UA62023C2/uk unknown
- 1999-11-19 DE DE69900891T patent/DE69900891D1/de not_active Expired - Lifetime
- 1999-11-19 SK SK1841-2001A patent/SK18412001A3/sk unknown
- 1999-11-19 CH CH00307/01A patent/CH691304A5/de not_active IP Right Cessation
- 1999-11-19 EP EP99968206A patent/EP1105382B1/de not_active Expired - Lifetime
- 1999-11-19 JP JP2000567065A patent/JP3389571B2/ja not_active Expired - Fee Related
- 1999-11-22 CA CA002290125A patent/CA2290125C/en not_active Expired - Fee Related
2000
- 2000-06-21 AR ARP000103080A patent/AR020573A1/es unknown
2001
- 2001-01-19 NO NO20010318A patent/NO20010318L/no unknown
- 2001-01-24 SE SE0100194A patent/SE516689C2/sv not_active IP Right Cessation
- 2001-01-25 FI FI20010154A patent/FI108538B/fi not_active IP Right Cessation
- 2001-02-23 IS IS5862A patent/IS5862A/is unknown
- 2001-03-13 AT AT0018501U patent/AT4366U1/de not_active IP Right Cessation
- 2001-10-26 ZA ZA200108855A patent/ZA200108855B/xx unknown
- 2001-11-06 US US10/012,025 patent/US6750358B2/en not_active Expired - Fee Related
- 2001-12-07 BG BG106190A patent/BG106190A/xx unknown

Also Published As

Publication number	Publication date
HK1047745B (zh)	2004-09-10
ATA904099A (de)	2002-05-15
CH691304A5 (de)	2001-06-29
GB2354240A (en)	2001-03-21
SI1105382T1 (en)	2002-06-30
NO20010318D0 (no)	2001-01-19
WO2000011926A3 (en)	2000-06-29
AU2001100433B4 (en)	2002-01-17
FI108538B (fi)	2002-02-15
EP1105382A2 (de)	2001-06-13
PT1105382E (pt)	2002-07-31
CZ292174B6 (cs)	2003-08-13
ATE213237T1 (de)	2002-02-15
EP1105382B1 (de)	2002-02-13
US20020061925A1 (en)	2002-05-23
ITMI991579A1 (it)	2001-01-15
GB0101508D0 (en)	2001-03-07
AT4366U1 (de)	2001-06-25
AU2001100433A4 (en)	2001-11-01
ES2172356T3 (es)	2002-09-16
CN1129593C (zh)	2003-12-03
TR200103700T2 (tr)	2002-05-21
SE0100194D0 (sv)	2001-01-24
DE19983486C2 (de)	2002-09-05
KR100491369B1 (ko)	2005-05-24
BG106190A (en)	2002-08-30
EA200101071A1 (ru)	2002-02-28
HUP0103417A3 (en)	2003-01-28
SE516689C2 (sv)	2002-02-12
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CN1356993A (zh)	2002-07-03
GB2354240B (en)	2001-05-23
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CA2290125C (en)	2004-08-10
CA2290125A1 (en)	2000-12-25
DE69900891D1 (de)	2002-03-21
ITMI991579A0 (it)	1999-07-15
IS5862A (is)	2001-02-23
AU1374800A (en)	2000-03-21
AR020573A1 (es)	2002-05-15
HK1047745A1 (en)	2003-03-07
HUP0103417A2 (hu)	2002-01-28
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