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CN1228119B - 用于病毒生长的固定化细胞系 - Google Patents

用于病毒生长的固定化细胞系 Download PDF

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Publication number
CN1228119B
CN1228119B CN971972818A CN97197281A CN1228119B CN 1228119 B CN1228119 B CN 1228119B CN 971972818 A CN971972818 A CN 971972818A CN 97197281 A CN97197281 A CN 97197281A CN 1228119 B CN1228119 B CN 1228119B
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Prior art keywords
cells
cell
virus
immortalized
culture
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Expired - Lifetime
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CN971972818A
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English (en)
Chinese (zh)
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CN1228119A (zh
Inventor
D·N·福斯特
L·K·福斯特
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University of Minnesota System
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University of Minnesota System
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C12N15/867—Retroviral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/04—Immortalised cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16651—Methods of production or purification of viral material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12051—Methods of production or purification of viral material

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Rheumatology (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN971972818A 1996-08-13 1997-08-13 用于病毒生长的固定化细胞系 Expired - Lifetime CN1228119B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/696,200 US5672485A (en) 1996-08-13 1996-08-13 Immortalized cell lines for virus growth
US08/696,200 1996-08-13
PCT/US1997/014384 WO1998006824A1 (en) 1996-08-13 1997-08-13 Immortalized cell lines for virus growth

Publications (2)

Publication Number Publication Date
CN1228119A CN1228119A (zh) 1999-09-08
CN1228119B true CN1228119B (zh) 2012-04-04

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CN971972818A Expired - Lifetime CN1228119B (zh) 1996-08-13 1997-08-13 用于病毒生长的固定化细胞系

Country Status (28)

Country Link
US (4) US5672485A (es)
EP (1) EP0920491B1 (es)
JP (3) JP3754088B2 (es)
KR (1) KR100375871B1 (es)
CN (1) CN1228119B (es)
AR (1) AR008294A1 (es)
AT (1) ATE362524T1 (es)
AU (1) AU726820B2 (es)
BR (1) BR9711067A (es)
CA (1) CA2263725C (es)
CO (1) CO4700552A1 (es)
DE (1) DE69737735T2 (es)
DK (1) DK0920491T3 (es)
DZ (1) DZ2291A1 (es)
ES (1) ES2285738T3 (es)
GT (1) GT199700091A (es)
HN (1) HN1997000124A (es)
HU (1) HU226658B1 (es)
IL (4) IL128511A (es)
MA (1) MA24303A1 (es)
MY (1) MY125594A (es)
NZ (1) NZ334147A (es)
PE (1) PE108198A1 (es)
PT (1) PT920491E (es)
SV (1) SV1997000071A (es)
UY (1) UY24668A1 (es)
WO (1) WO1998006824A1 (es)
ZA (1) ZA977216B (es)

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US6150505A (en) * 1997-09-19 2000-11-21 Hadasit Medical Research Services & Development Ltd. Fibrin microbeads prepared from fibrinogen, thrombin and factor XIII
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US6552172B2 (en) 2001-08-30 2003-04-22 Habto Biotech, Inc. Fibrin nanoparticles and uses thereof
US20040210954A1 (en) * 2003-03-07 2004-10-21 Alex Harvey Integrase mediated avian transgenesis
US20040023358A1 (en) * 2001-12-21 2004-02-05 Wyeth Avian embryo particulate biomass for the production of virus antigens
FR2836924B1 (fr) 2002-03-08 2005-01-14 Vivalis Lignees de cellules aviaires utiles pour la production de substances d'interet
US20090217404A1 (en) * 2002-09-27 2009-08-27 Lowe Scott W Cell-based RNA interference and related methods and compositions
JPWO2004031450A1 (ja) * 2002-09-30 2006-02-02 本田技研工業株式会社 水素活性化装置
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US20090186839A1 (en) * 2003-02-17 2009-07-23 Cold Spring Harbor Laboratory Model for studying the role of genes in chemoresistance
EP1599573B1 (en) * 2003-02-17 2013-06-19 Cold Spring Harbor Laboratory Model for studying the role of genes in tumor resistance to chemotherapy
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US20040255345A1 (en) * 2003-03-07 2004-12-16 Rapp Jeffrey C. Production of transgenic avians
US20050034186A1 (en) * 2003-03-07 2005-02-10 Harvey Alex J. Site specific nucleic acid integration
PT1646715E (pt) 2003-07-22 2010-08-09 Vivalis Produção de poxvírus com linhagem das células aviarias aderentes ou não aderentes
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US20060174364A1 (en) * 2004-03-01 2006-08-03 Avigenics, Inc. Artificial chromosomes and transchromosomic avians
WO2006042214A1 (en) * 2004-10-08 2006-04-20 Avigenics, Inc. Modified integrase and methods of use
US8137907B2 (en) * 2005-01-03 2012-03-20 Cold Spring Harbor Laboratory Orthotopic and genetically tractable non-human animal model for liver cancer and the uses thereof
FR2884255B1 (fr) 2005-04-11 2010-11-05 Vivalis Utilisation de lignees de cellules souches aviaires ebx pour la production de vaccin contre la grippe
US20070044164A1 (en) * 2005-05-31 2007-02-22 Cold Spring Harbor Laboratory Methods for producing microRNAs
US7524626B2 (en) * 2005-10-05 2009-04-28 Synageva Biopharma Corp. Rapid production of high titer virus
DK2029756T3 (en) 2006-06-20 2017-02-13 Transgene Sa PROCEDURE FOR PREPARING POXVIRA AND POXVIRUS COMPOSITIONS
CN100443588C (zh) * 2006-12-11 2008-12-17 中国农业科学院北京畜牧兽医研究所 静宁鸡胚成纤维细胞系及其培养方法
US8213704B2 (en) * 2007-05-09 2012-07-03 Kla-Tencor Corp. Methods and systems for detecting defects in a reticle design pattern
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US8357531B2 (en) 2007-07-03 2013-01-22 Transgene S.A. Immortalized avian cell lines
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JP5653223B2 (ja) 2008-02-25 2015-01-14 バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ 連続細胞系の生成方法
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JP7334124B2 (ja) 2017-06-21 2023-08-28 トランジェーヌ 個別化ワクチン
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Also Published As

Publication number Publication date
CA2263725A1 (en) 1998-02-19
ES2285738T3 (es) 2007-11-16
KR100375871B1 (ko) 2003-03-10
IL158303A0 (en) 2004-05-12
BR9711067A (pt) 1999-08-17
JP3754088B2 (ja) 2006-03-08
HUP0000188A2 (hu) 2000-06-28
US5672485A (en) 1997-09-30
US5985642A (en) 1999-11-16
AU4069197A (en) 1998-03-06
EP0920491A1 (en) 1999-06-09
US6207415B1 (en) 2001-03-27
PT920491E (pt) 2007-07-27
DE69737735D1 (de) 2007-06-28
ATE362524T1 (de) 2007-06-15
JP2006320328A (ja) 2006-11-30
EP0920491B1 (en) 2007-05-16
HU226658B1 (en) 2009-06-29
MA24303A1 (fr) 1998-04-01
IL128511A0 (en) 2000-01-31
GT199700091A (es) 1997-08-12
IL158302A0 (en) 2004-05-12
IL128511A (en) 2004-06-01
HK1022496A1 (en) 2000-08-11
ZA977216B (en) 1998-02-19
DK0920491T3 (da) 2007-09-17
DE69737735T2 (de) 2008-01-31
US5879924A (en) 1999-03-09
KR20000029968A (ko) 2000-05-25
NZ334147A (en) 2000-08-25
AR008294A1 (es) 1999-12-29
PE108198A1 (es) 1999-01-21
IL158301A0 (en) 2004-05-12
HUP0000188A3 (en) 2005-11-28
WO1998006824A1 (en) 1998-02-19
HN1997000124A (es) 1999-03-19
SV1997000071A (es) 2000-07-06
JP2000516095A (ja) 2000-12-05
CN1228119A (zh) 1999-09-08
CO4700552A1 (es) 1998-12-29
MY125594A (en) 2006-08-30
UY24668A1 (es) 1998-02-02
DZ2291A1 (fr) 2002-12-25
AU726820B2 (en) 2000-11-23
CA2263725C (en) 2002-10-15
JP2005118053A (ja) 2005-05-12

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