AR069128A1 - Forma de dosificacion que se desintegra oralmente y proceso de preparacion - Google Patents
Forma de dosificacion que se desintegra oralmente y proceso de preparacionInfo
- Publication number
- AR069128A1 AR069128A1 ARP080104761A ARP080104761A AR069128A1 AR 069128 A1 AR069128 A1 AR 069128A1 AR P080104761 A ARP080104761 A AR P080104761A AR P080104761 A ARP080104761 A AR P080104761A AR 069128 A1 AR069128 A1 AR 069128A1
- Authority
- AR
- Argentina
- Prior art keywords
- dosage form
- group
- orally
- hydrate
- active agent
- Prior art date
Links
- 239000002552 dosage form Substances 0.000 title abstract 8
- 238000002360 preparation method Methods 0.000 title 1
- 239000013543 active substance Substances 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- 239000007787 solid Substances 0.000 abstract 3
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 abstract 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 2
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 abstract 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 2
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 abstract 2
- 235000009508 confectionery Nutrition 0.000 abstract 2
- 229960001031 glucose Drugs 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- SPFMQWBKVUQXJV-BTVCFUMJSA-N (2r,3s,4r,5r)-2,3,4,5,6-pentahydroxyhexanal;hydrate Chemical compound O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O SPFMQWBKVUQXJV-BTVCFUMJSA-N 0.000 abstract 1
- SERLAGPUMNYUCK-DCUALPFSSA-N 1-O-alpha-D-glucopyranosyl-D-mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O SERLAGPUMNYUCK-DCUALPFSSA-N 0.000 abstract 1
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 abstract 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 abstract 1
- ZKLPARSLTMPFCP-UHFFFAOYSA-N Cetirizine Chemical compound C1CN(CCOCC(=O)O)CCN1C(C=1C=CC(Cl)=CC=1)C1=CC=CC=C1 ZKLPARSLTMPFCP-UHFFFAOYSA-N 0.000 abstract 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 abstract 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 abstract 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 abstract 1
- WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 abstract 1
- 239000004386 Erythritol Substances 0.000 abstract 1
- UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 abstract 1
- 229930091371 Fructose Natural products 0.000 abstract 1
- 239000005715 Fructose Substances 0.000 abstract 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 abstract 1
- 229920001908 Hydrogenated starch hydrolysate Polymers 0.000 abstract 1
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 abstract 1
- MKXZASYAUGDDCJ-SZMVWBNQSA-N LSM-2525 Chemical compound C1CCC[C@H]2[C@@]3([H])N(C)CC[C@]21C1=CC(OC)=CC=C1C3 MKXZASYAUGDDCJ-SZMVWBNQSA-N 0.000 abstract 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 1
- 229920002774 Maltodextrin Polymers 0.000 abstract 1
- 239000005913 Maltodextrin Substances 0.000 abstract 1
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 abstract 1
- 229930195725 Mannitol Natural products 0.000 abstract 1
- 108010009736 Protein Hydrolysates Proteins 0.000 abstract 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract 1
- 229930006000 Sucrose Natural products 0.000 abstract 1
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 abstract 1
- 240000008042 Zea mays Species 0.000 abstract 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 abstract 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 abstract 1
- 239000011668 ascorbic acid Substances 0.000 abstract 1
- 229960005070 ascorbic acid Drugs 0.000 abstract 1
- 235000010323 ascorbic acid Nutrition 0.000 abstract 1
- 239000011324 bead Substances 0.000 abstract 1
- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 229910000019 calcium carbonate Inorganic materials 0.000 abstract 1
- 229960003563 calcium carbonate Drugs 0.000 abstract 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 235000014633 carbohydrates Nutrition 0.000 abstract 1
- 229960001803 cetirizine Drugs 0.000 abstract 1
- 235000005822 corn Nutrition 0.000 abstract 1
- 230000018044 dehydration Effects 0.000 abstract 1
- 238000006297 dehydration reaction Methods 0.000 abstract 1
- 230000008021 deposition Effects 0.000 abstract 1
- 229960001985 dextromethorphan Drugs 0.000 abstract 1
- 239000008121 dextrose Substances 0.000 abstract 1
- 229960000673 dextrose monohydrate Drugs 0.000 abstract 1
- MQRJBSHKWOFOGF-UHFFFAOYSA-L disodium;carbonate;hydrate Chemical compound O.[Na+].[Na+].[O-]C([O-])=O MQRJBSHKWOFOGF-UHFFFAOYSA-L 0.000 abstract 1
- HFCSXCKLARAMIQ-UHFFFAOYSA-L disodium;sulfate;hydrate Chemical compound O.[Na+].[Na+].[O-]S([O-])(=O)=O HFCSXCKLARAMIQ-UHFFFAOYSA-L 0.000 abstract 1
- 235000019414 erythritol Nutrition 0.000 abstract 1
- UNXHWFMMPAWVPI-ZXZARUISSA-N erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 abstract 1
- 229940009714 erythritol Drugs 0.000 abstract 1
- XUFQPHANEAPEMJ-UHFFFAOYSA-N famotidine Chemical compound NC(N)=NC1=NC(CSCCC(N)=NS(N)(=O)=O)=CS1 XUFQPHANEAPEMJ-UHFFFAOYSA-N 0.000 abstract 1
- 229960001596 famotidine Drugs 0.000 abstract 1
- 229960002737 fructose Drugs 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 229960001680 ibuprofen Drugs 0.000 abstract 1
- 239000000905 isomalt Substances 0.000 abstract 1
- 235000010439 isomalt Nutrition 0.000 abstract 1
- HPIGCVXMBGOWTF-UHFFFAOYSA-N isomaltol Natural products CC(=O)C=1OC=CC=1O HPIGCVXMBGOWTF-UHFFFAOYSA-N 0.000 abstract 1
- DKYWVDODHFEZIM-UHFFFAOYSA-N ketoprofen Chemical compound OC(=O)C(C)C1=CC=CC(C(=O)C=2C=CC=CC=2)=C1 DKYWVDODHFEZIM-UHFFFAOYSA-N 0.000 abstract 1
- 229960000991 ketoprofen Drugs 0.000 abstract 1
- 239000000832 lactitol Substances 0.000 abstract 1
- 235000010448 lactitol Nutrition 0.000 abstract 1
- VQHSOMBJVWLPSR-JVCRWLNRSA-N lactitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-JVCRWLNRSA-N 0.000 abstract 1
- 229960003451 lactitol Drugs 0.000 abstract 1
- 239000008101 lactose Substances 0.000 abstract 1
- 229960001375 lactose Drugs 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- RDOIQAHITMMDAJ-UHFFFAOYSA-N loperamide Chemical compound C=1C=CC=CC=1C(C=1C=CC=CC=1)(C(=O)N(C)C)CCN(CC1)CCC1(O)C1=CC=C(Cl)C=C1 RDOIQAHITMMDAJ-UHFFFAOYSA-N 0.000 abstract 1
- 229960001571 loperamide Drugs 0.000 abstract 1
- 229940035034 maltodextrin Drugs 0.000 abstract 1
- 239000000594 mannitol Substances 0.000 abstract 1
- 235000010355 mannitol Nutrition 0.000 abstract 1
- 229960001855 mannitol Drugs 0.000 abstract 1
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 abstract 1
- 229960005489 paracetamol Drugs 0.000 abstract 1
- SONNWYBIRXJNDC-VIFPVBQESA-N phenylephrine Chemical compound CNC[C@H](O)C1=CC=CC(O)=C1 SONNWYBIRXJNDC-VIFPVBQESA-N 0.000 abstract 1
- 229960001802 phenylephrine Drugs 0.000 abstract 1
- 238000005096 rolling process Methods 0.000 abstract 1
- 235000019980 sodium acid phosphate Nutrition 0.000 abstract 1
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 abstract 1
- HPALAKNZSZLMCH-UHFFFAOYSA-M sodium;chloride;hydrate Chemical compound O.[Na+].[Cl-] HPALAKNZSZLMCH-UHFFFAOYSA-M 0.000 abstract 1
- 239000000600 sorbitol Substances 0.000 abstract 1
- 229960002920 sorbitol Drugs 0.000 abstract 1
- 235000010356 sorbitol Nutrition 0.000 abstract 1
- 239000005720 sucrose Substances 0.000 abstract 1
- 239000006188 syrup Substances 0.000 abstract 1
- 235000020357 syrup Nutrition 0.000 abstract 1
- 239000000811 xylitol Substances 0.000 abstract 1
- 235000010447 xylitol Nutrition 0.000 abstract 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 abstract 1
- 229960002675 xylitol Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Zoology (AREA)
- Inorganic Chemistry (AREA)
- Physiology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La presente invencion presenta una forma de dosificacion que se desintegra oralmente incluyendo desde alrededor de 5% hasta alrededor de 40%, en peso, de al menos una sal hidratada y un agente farmacéuticamente activo, en donde la al menos sal hidratada tiene una temperatura de deshidratacion de desde alrededor de 20 hasta alrededor de 120°C. Reivindicacion 4: La forma de dosificacion que se desintegra oralmente de conformidad con la reivindicacion 3, caracterizada porque el al menos un carbohidrato se selecciona del grupo que consiste de dextrosa, monohidrato de dextrosa, lactosa, glucosa, fructosa, isomalta, sucrosa, manosa, maltosa, maltodextrina, solidos de jarabe de maíz, hidrolisados de almidon hidrogenado, lactitol, xilitol, manitol, eritritol, y sorbitol, y mezclas de los mismos. Reivindicacion 6: La forma de dosificacion que se desintegra oralmente de conformidad con la reivindicacion 1, caracterizada porque la al menos una sal hidratada se selecciona del grupo que consiste de hidrato del sulfato de sodio, hidrato del carbonato de sodio, hidrato del cloruro de sodio, hidrato del fosfato ácido de sodio, y mezclas de los mismos. Reivindicacion 8: La forma de dosificacion que se desintegra oralmente de conformidad con la reivindicacion 1, caracterizada porque el agente farmacéuticamente activo se selecciona del grupo que consiste de acetaminofen, ibuprofen, cetoprofen, loperamida, famotidina, cetirizina, fenilefrina, dextrometorfano, carbonato de calcio, ácido ascorbico, y difenihidramina. Reivindicacion 9: La forma de dosificacion que se desintegra oralmente de conformidad con la reivindicacion 1, caracterizada porque comprende perlas rellenas de líquido recubiertas de gel. Reivindicacion 16: La forma de dosificacion de conformidad con la reivindicacion 15,. caracterizada porque la porcion exterior comestible comprende un agente farmacéuticamente activo Reivindicacion 17: La forma de dosificacion de conformidad con la reivindicacion 15, caracterizada porque la porcion exterior comestible es un caramelo macizo. Reivindicacion 20. El proceso de conformidad con la reivindicacion 18 caracterizada porque la porcion exterior comestible es un caramelo macizo exterior preparado por un método seleccionado del grupo que consiste de rolado uniplast, formacion de cordeles, y el posterior corte y estampado, o deposicion en un molde.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98397307P | 2007-10-31 | 2007-10-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR069128A1 true AR069128A1 (es) | 2009-12-30 |
Family
ID=40184970
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP080104761A AR069128A1 (es) | 2007-10-31 | 2008-10-30 | Forma de dosificacion que se desintegra oralmente y proceso de preparacion |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US20090110716A1 (es) |
| EP (1) | EP2217213B1 (es) |
| KR (1) | KR101560176B1 (es) |
| CN (1) | CN101842085B (es) |
| AR (1) | AR069128A1 (es) |
| AU (1) | AU2008318851B2 (es) |
| BR (1) | BRPI0819231B8 (es) |
| CA (1) | CA2704209C (es) |
| ES (1) | ES2633449T3 (es) |
| MX (1) | MX2010004897A (es) |
| RU (1) | RU2482839C2 (es) |
| WO (1) | WO2009058798A2 (es) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090060983A1 (en) * | 2007-08-30 | 2009-03-05 | Bunick Frank J | Method And Composition For Making An Orally Disintegrating Dosage Form |
| RU2482839C2 (ru) * | 2007-10-31 | 2013-05-27 | МакНЕЙЛС-ППС, ИНК. | Распадающаяся в полости рта лекарственная форма |
| US8313768B2 (en) | 2009-09-24 | 2012-11-20 | Mcneil-Ppc, Inc. | Manufacture of tablet having immediate release region and sustained release region |
| US20110318411A1 (en) | 2010-06-24 | 2011-12-29 | Luber Joseph R | Multi-layered orally disintegrating tablet and the manufacture thereof |
| US8343533B2 (en) * | 2009-09-24 | 2013-01-01 | Mcneil-Ppc, Inc. | Manufacture of lozenge product with radiofrequency |
| US20110070286A1 (en) * | 2009-09-24 | 2011-03-24 | Andreas Hugerth | Process for the manufacture of nicotine-comprising chewing gum and nicotine-comprising chewing gum manufactured according to said process |
| MA34262B1 (fr) * | 2010-05-31 | 2013-05-02 | Haremlik Gida Dekorasyon Ve Ekipmanlari Ticaret Sanayi Ltd Sirketi | Capsule pour le versement d'une poudre dans un dispositif |
| US9511028B2 (en) | 2012-05-01 | 2016-12-06 | Johnson & Johnson Consumer Inc. | Orally disintegrating tablet |
| US9233491B2 (en) | 2012-05-01 | 2016-01-12 | Johnson & Johnson Consumer Inc. | Machine for production of solid dosage forms |
| US9445971B2 (en) | 2012-05-01 | 2016-09-20 | Johnson & Johnson Consumer Inc. | Method of manufacturing solid dosage form |
| US20150283083A1 (en) * | 2012-11-19 | 2015-10-08 | Azanta A/S | Dispersible Tablet |
| ES2761407T3 (es) * | 2013-03-15 | 2020-05-19 | Aprecia Pharmaceuticals LLC | Forma de dosificación rápidamente dispersable de topiramato |
| WO2015050283A1 (ko) * | 2013-10-02 | 2015-04-09 | 이상헌 | 식욕억제용 한방 구강붕해정제 및 그 제조방법 |
| RU2712267C2 (ru) | 2014-01-10 | 2020-01-28 | Джонсон энд Джонсон Консьюмер Инк. | Способ изготовления таблеток с использованием радиочастотного излучения и частиц с поглощающим покрытием |
| DE202015004009U1 (de) | 2015-06-09 | 2016-01-11 | Hermes Arzneimittel Gmbh | Schnell zerfallende Tabletten ohne Zerfallsbeschleuniger |
| RU2625737C2 (ru) * | 2015-07-13 | 2017-07-18 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Ставропольский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО СтГМУ Минздрава России) | Шипучий фитоминеральный комплекс с антидиабетическим действием |
| CN107921471B (zh) | 2015-08-21 | 2023-05-23 | 阿普雷奇亚制药有限责任公司 | 三维打印系统和设备组件 |
| WO2018004391A1 (ru) * | 2016-06-29 | 2018-01-04 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Фармацевтическая композиция, содержащая комбинацию мемантина и мелатонина |
| DE202016005032U1 (de) | 2016-08-19 | 2017-02-10 | Hermes Arzneimittel Gmbh | Schnell zerfallende Efeu-Trinktabletten ohne Zerfallsbeschleuniger |
| US10493026B2 (en) | 2017-03-20 | 2019-12-03 | Johnson & Johnson Consumer Inc. | Process for making tablet using radiofrequency and lossy coated particles |
| JP7614103B2 (ja) | 2018-10-15 | 2025-01-15 | アプレシア・ファーマスーティカルズ・エルエルシー | 包装内に剤形を形成する方法およびシステム |
| MX2022016117A (es) | 2020-06-26 | 2023-04-05 | Aprecia Pharmaceuticals LLC | Tabletas rapidamente orodispersables que tienen una cavidad interior. |
Family Cites Families (173)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2183053A (en) * | 1936-12-03 | 1939-12-12 | Atlantic Coast Fisheries Co | Vitamin preparation and method of making same |
| BE536822A (es) | 1954-03-25 | |||
| US2887437A (en) * | 1956-08-22 | 1959-05-19 | Pfizer & Co C | Palatable vitamin tablet containing an amino acid |
| US3071470A (en) | 1959-12-24 | 1963-01-01 | Bishop Lee Porter | Method for preparing soluble coffee wafers |
| GB1097207A (en) | 1964-08-24 | 1967-12-29 | Collett & Co As | Process for the preparation of sustained action tablets |
| US3337116A (en) | 1965-06-09 | 1967-08-22 | Container Corp | Snap lock arrangement |
| NL6808619A (es) * | 1968-06-19 | 1969-12-23 | ||
| DE2246013A1 (de) * | 1972-09-20 | 1974-03-28 | Boehringer Mannheim Gmbh | Verfahren zur herstellung von poroesen tabletten |
| CA1063935A (en) | 1975-04-21 | 1979-10-09 | Frederick G. Wheeler | Antacid tablets and processes for their preparation |
| US4230693A (en) | 1975-04-21 | 1980-10-28 | Armour-Dial, Inc. | Antacid tablets and processes for their preparation |
| US4368634A (en) * | 1975-12-29 | 1983-01-18 | Kennametal Inc. | Extrusion punch and method of construction |
| US4158411A (en) * | 1976-05-10 | 1979-06-19 | Hall Douglas C | Dispensing package |
| US4268465A (en) | 1978-01-27 | 1981-05-19 | Massachusetts Institute Of Technology | Method of accelerating the cooling of polymeric articles |
| US4268238A (en) * | 1978-03-13 | 1981-05-19 | Clint, Inc. | Flow molding |
| US4173626A (en) * | 1978-12-11 | 1979-11-06 | Merck & Co., Inc. | Sustained release indomethacin |
| US4260596A (en) * | 1979-08-13 | 1981-04-07 | Bristol-Myers Company | Edible unit dosage form consisting of outer mannitol shell and inner liquid or gel center and method for manufacturing the same |
| US4327076A (en) | 1980-11-17 | 1982-04-27 | Life Savers, Inc. | Compressed chewable antacid tablet and method for forming same |
| EP0070127A3 (en) | 1981-07-10 | 1983-08-17 | Beecham Group Plc | Tablets |
| US4398634A (en) | 1981-11-12 | 1983-08-16 | Wrapade Machine Company, Inc. | Child-proof package system |
| US4994260A (en) * | 1982-05-28 | 1991-02-19 | Astra Lakemedel Aktiebolag | Pharmaceutical mixture |
| JPS5967006A (ja) | 1982-10-08 | 1984-04-16 | Hitachi Ltd | タブレツト成形機 |
| GB2137470B (en) | 1983-04-08 | 1986-11-26 | Meiji Seika Kaisha | Fleecy confectionery producing machine |
| US4508740A (en) | 1983-07-11 | 1985-04-02 | General Foods Corporation | Tabletted beverage composition containing dipeptide sweetener and process therefore |
| US4609543A (en) * | 1983-11-14 | 1986-09-02 | Nabisco Brands, Inc. | Soft homogeneous antacid tablet |
| US4758439A (en) | 1984-06-11 | 1988-07-19 | Godfrey Science & Design, Inc. | Flavor of zinc supplements for oral use |
| US4590075A (en) * | 1984-08-27 | 1986-05-20 | Warner-Lambert Company | Elastomer encapsulation of flavors and sweeteners, long lasting flavored chewing gum compositions based thereon and process of preparation |
| US4684534A (en) | 1985-02-19 | 1987-08-04 | Dynagram Corporation Of America | Quick-liquifying, chewable tablet |
| US4642903A (en) * | 1985-03-26 | 1987-02-17 | R. P. Scherer Corporation | Freeze-dried foam dosage form |
| EP0272265B1 (de) * | 1985-09-25 | 1991-05-22 | Gergely, Gerhard, Dr. | Zerfallstablette und verfahren zu ihrer herstellung |
| JPS62205009A (ja) | 1986-03-05 | 1987-09-09 | Kanebo Ltd | 受皿入り多色固形化粧料の製造方法 |
| IE58401B1 (en) * | 1986-06-20 | 1993-09-08 | Elan Corp Plc | Controlled absorption pharmaceutical composition |
| US4762719A (en) * | 1986-08-07 | 1988-08-09 | Mark Forester | Powder filled cough product |
| US4828845A (en) | 1986-12-16 | 1989-05-09 | Warner-Lambert Company | Xylitol coated comestible and method of preparation |
| US4824681A (en) * | 1986-12-19 | 1989-04-25 | Warner-Lambert Company | Encapsulated sweetener composition for use with chewing gum and edible products |
| US4777050A (en) | 1987-03-23 | 1988-10-11 | Schering Corporation | Controlled-release dosage form comprising acetaminophen, pseudoephedrine and dexbrompheniramine |
| US4851226A (en) * | 1987-11-16 | 1989-07-25 | Mcneil Consumer Products Company | Chewable medicament tablet containing means for taste masking |
| US4979720A (en) * | 1987-11-30 | 1990-12-25 | Jeffrey Robinson | Injection mold having interchangeable inscription plates |
| US4857331A (en) * | 1988-03-31 | 1989-08-15 | Warner-Lambert Company | Sugarless pectin delivery system |
| DE3822095A1 (de) * | 1988-06-30 | 1990-01-04 | Klinge Co Chem Pharm Fab | Neue arzneimittelformulierung sowie verfahren zu deren herstellung |
| US5073374A (en) * | 1988-11-30 | 1991-12-17 | Schering Corporation | Fast dissolving buccal tablet |
| US5112616A (en) * | 1988-11-30 | 1992-05-12 | Schering Corporation | Fast dissolving buccal tablet |
| US4906478A (en) * | 1988-12-12 | 1990-03-06 | Valentine Enterprises, Inc. | Simethicone/calcium silicate composition |
| US4984240A (en) * | 1988-12-22 | 1991-01-08 | Codex Corporation | Distributed switching architecture for communication module redundancy |
| US5082436A (en) * | 1989-07-14 | 1992-01-21 | General Electric Company | Apparatus for deforming thermoplastic material using RF heating |
| NZ234587A (en) * | 1989-08-04 | 1991-11-26 | Mcneil Ppc Inc | A chewable pharmaceutical tablet of compressed coated granules |
| US5139407A (en) | 1989-09-01 | 1992-08-18 | General Electric Company | Apparatus for reducing thermoplastic material compression mold cycle time |
| EP0416791A2 (en) | 1989-09-08 | 1991-03-13 | General Motors Corporation | Method and apparatus for compression moulding with dielectric heating |
| US5178878A (en) * | 1989-10-02 | 1993-01-12 | Cima Labs, Inc. | Effervescent dosage form with microparticles |
| US5223264A (en) * | 1989-10-02 | 1993-06-29 | Cima Labs, Inc. | Pediatric effervescent dosage form |
| US5013557A (en) * | 1989-10-03 | 1991-05-07 | Warner-Lambert Company | Taste masking compositions comprising spray dried microcapsules containing sucralfate and methods for preparing same |
| US5275822A (en) * | 1989-10-19 | 1994-01-04 | Valentine Enterprises, Inc. | Defoaming composition |
| US5064656A (en) * | 1989-11-14 | 1991-11-12 | Dr. Gergely & Co. | Uncoated pharmaceutical reaction tablet |
| US5558880A (en) * | 1989-12-22 | 1996-09-24 | Janssen Pharmaceutica Inc. | Pharmaceutical and other dosage forms |
| US5215756A (en) * | 1989-12-22 | 1993-06-01 | Gole Dilip J | Preparation of pharmaceutical and other matrix systems by solid-state dissolution |
| DE4005328A1 (de) | 1990-02-20 | 1991-08-22 | Technics Plasma Gmbh | Verfahren zur konditionierung eines pulvers und vorrichtung dafuer |
| US5075114A (en) * | 1990-05-23 | 1991-12-24 | Mcneil-Ppc, Inc. | Taste masking and sustained release coatings for pharmaceuticals |
| US5134260A (en) * | 1990-06-27 | 1992-07-28 | Carnegie-Mellon University | Method and apparatus for inductively heating powders or powder compacts for consolidation |
| SE9003296L (sv) | 1990-10-16 | 1992-04-17 | Kabi Pharmacia Ab | Foerfarande foer att formulera laekemedel |
| US5046618A (en) * | 1990-11-19 | 1991-09-10 | R. P. Scherer Corporation | Child-resistant blister pack |
| US5126151A (en) * | 1991-01-24 | 1992-06-30 | Warner-Lambert Company | Encapsulation matrix |
| US5286497A (en) * | 1991-05-20 | 1994-02-15 | Carderm Capital L.P. | Diltiazem formulation |
| EP0587744B1 (en) | 1991-05-28 | 2003-07-16 | McNEIL-PPC, Inc. | Chewable drug-delivery composition |
| CA2068402C (en) * | 1991-06-14 | 1998-09-22 | Michael R. Hoy | Taste mask coatings for preparation of chewable pharmaceutical tablets |
| US5464632C1 (en) * | 1991-07-22 | 2001-02-20 | Prographarm Lab | Rapidly disintegratable multiparticular tablet |
| US5326570A (en) * | 1991-07-23 | 1994-07-05 | Pharmavene, Inc. | Advanced drug delivery system and method of treating psychiatric, neurological and other disorders with carbamazepine |
| US5236636A (en) | 1991-10-07 | 1993-08-17 | Ford Motor Company | In-mold plasma treatment |
| US5262171A (en) * | 1991-11-25 | 1993-11-16 | Isp Investments Inc. | Pharmaceutical tablet with PVP having enhanced drug dissolution rate |
| US5304055A (en) | 1991-11-27 | 1994-04-19 | Nabisco, Inc. | Apparatus and methods for the production of three-dimensional food products |
| JP2640570B2 (ja) | 1992-01-13 | 1997-08-13 | ファイザー インク． | 強度が増加した錠剤の製造 |
| MX9300110A (es) * | 1992-01-13 | 1994-07-29 | Gerhard Gergely | Preparacion farmaceutica en la forma de una tableta de efervescencia o de desintegracion o de un granulado de tipo instanteneo y procedimiento para su preparacion. |
| DE69331839T2 (de) * | 1992-01-29 | 2002-12-12 | Takeda Chemical Industries, Ltd. | Schnellösliche Tablette und ihre Herstellung |
| DE4214270A1 (de) * | 1992-04-30 | 1993-11-04 | Thomson Brandt Gmbh | Bandandruckrollen-betaetigungsvorrichtung |
| CA2095776C (en) * | 1992-05-12 | 2007-07-10 | Richard C. Fuisz | Rapidly dispersable compositions containing polydextrose |
| IT1255522B (it) | 1992-09-24 | 1995-11-09 | Ubaldo Conte | Compressa per impiego terapeutico atta a cedere una o piu' sostanze attive con differenti velocita' |
| US5503846A (en) * | 1993-03-17 | 1996-04-02 | Cima Labs, Inc. | Base coated acid particles and effervescent formulation incorporating same |
| DE69429119T2 (de) * | 1993-07-09 | 2002-07-18 | R.P. Scherer Corp., Troy | Verfahren zur herstellung von gefriergetrockneten arzneistoffdosierungsformen |
| ZA945944B (en) * | 1993-08-13 | 1996-02-08 | Eurand America Inc | Procedure for encapsulating nsaids |
| US5622719A (en) * | 1993-09-10 | 1997-04-22 | Fuisz Technologies Ltd. | Process and apparatus for making rapidly dissolving dosage units and product therefrom |
| US5662849A (en) * | 1993-09-10 | 1997-09-02 | Fulsz Technologies Ltd. | Method and apparatus for forming compression dosage units within the product package |
| US5895664A (en) * | 1993-09-10 | 1999-04-20 | Fuisz Technologies Ltd. | Process for forming quickly dispersing comestible unit and product therefrom |
| WO1995009044A1 (en) | 1993-09-29 | 1995-04-06 | E.I. Du Pont De Nemours And Company | Melt granulation with dielectric heating |
| NL9400040A (nl) | 1994-01-10 | 1995-08-01 | Suiker Unie | Werkwijze voor het bereiden van polysaccharidederivaten. |
| US5635210A (en) * | 1994-02-03 | 1997-06-03 | The Board Of Regents Of The University Of Oklahoma | Method of making a rapidly dissolving tablet |
| JPH1133084A (ja) | 1994-02-10 | 1999-02-09 | Yamanouchi Pharmaceut Co Ltd | 口腔内溶解型錠剤およびその製造方法 |
| TW466119B (en) | 1994-02-28 | 2001-12-01 | Janssen Pharmaceutica Nv | Film coated tablet of paracetamol and domperidone |
| US5672364A (en) | 1994-07-07 | 1997-09-30 | Sankyo Seisakusho Co. & Eisai Co., Ltd. | Apparatus for manufacturing tablets |
| US5607697A (en) * | 1995-06-07 | 1997-03-04 | Cima Labs, Incorporated | Taste masking microparticles for oral dosage forms |
| TR199802068T2 (xx) | 1996-04-16 | 2000-01-21 | Novartis Consumer Health S.A. | H�zl� b�l�nen oral doz formu. |
| DE69710460T2 (de) * | 1996-06-17 | 2002-10-02 | Janssen Pharmaceutica N.V., Beerse | Bikonvexe, rasch desintegrierende verabreichungsformen |
| WO1998002185A1 (en) | 1996-07-12 | 1998-01-22 | Daiichi Pharmaceutical Co., Ltd. | Quickly disintegrable compression-molded materials and process for producing the same |
| US6491900B2 (en) * | 1996-08-20 | 2002-12-10 | American Dental Association Health Foundation | Anti-carious candies and confections |
| IT1286212B1 (it) | 1996-09-11 | 1998-07-08 | Mg 2 Spa | Metodo e macchina per la produzione di pastiglie di polvere medicinale |
| US5891474A (en) * | 1997-01-29 | 1999-04-06 | Poli Industria Chimica, S.P.A. | Time-specific controlled release dosage formulations and method of preparing same |
| US6024981A (en) | 1997-04-16 | 2000-02-15 | Cima Labs Inc. | Rapidly dissolving robust dosage form |
| KR100238284B1 (ko) * | 1997-05-12 | 2000-01-15 | 윤종용 | 위상 보정 회로 및 그 방법 |
| US5939091A (en) | 1997-05-20 | 1999-08-17 | Warner Lambert Company | Method for making fast-melt tablets |
| ATE288742T1 (de) * | 1997-07-10 | 2005-02-15 | Gergely Dr & Co | Lösliche, gummihaltige, dragierte kautablette |
| US6103260A (en) * | 1997-07-17 | 2000-08-15 | Mcneil-Ppc, Inc. | Simethicone/anhydrous calcium phosphate compositions |
| US5886081A (en) * | 1997-08-05 | 1999-03-23 | Rockwell Science Center, Inc. | Efficient dielectrically heatable compound and method |
| JP2001518503A (ja) | 1997-10-02 | 2001-10-16 | ハー・ルンドベック・アクチエゼルスカベット | ５−（２−エチル−２ｈ−テトラゾール−５−イル）−１−メチル−１，２，３，６−テトラヒドロピリジンの粒状調合物 |
| US6612826B1 (en) | 1997-10-15 | 2003-09-02 | Iap Research, Inc. | System for consolidating powders |
| US5914128A (en) * | 1997-12-22 | 1999-06-22 | Schering Corporation | Orally administrable solid dosage form |
| NZ507271A (en) * | 1998-03-06 | 2003-03-28 | Eurand Internat S | Fast disintegrating tablets |
| US6589554B1 (en) * | 1998-03-16 | 2003-07-08 | Yamanouchi Pharmaceutical Co., Ltd. | Tablets quickly disintegrating in the oral cavity and process for producing the same |
| JP3746167B2 (ja) * | 1998-05-18 | 2006-02-15 | 武田薬品工業株式会社 | 医薬製剤 |
| DE19831520A1 (de) | 1998-07-14 | 2000-01-20 | Schaeffler Waelzlager Ohg | Elektromagnetischer Ventiltrieb |
| IL137665A0 (en) | 1998-07-17 | 2001-10-31 | Janssen Pharmaceutica Nv | Pellets having core coated with an antifungal and a polymer |
| US6358060B2 (en) * | 1998-09-03 | 2002-03-19 | Jsr Llc | Two-stage transmucosal medicine delivery system for symptom relief |
| US5997905A (en) | 1998-09-04 | 1999-12-07 | Mcneil-Ppc | Preparation of pharmaceutically active particles |
| JP2000095674A (ja) * | 1998-09-22 | 2000-04-04 | Sato Pharmaceutical Co Ltd | 口腔内崩壊時間短縮化錠剤の製造方法及び装置 |
| US6060078A (en) * | 1998-09-28 | 2000-05-09 | Sae Han Pharm Co., Ltd. | Chewable tablet and process for preparation thereof |
| US20010055613A1 (en) * | 1998-10-21 | 2001-12-27 | Beth A. Burnside | Oral pulsed dose drug delivery system |
| US7815937B2 (en) * | 1998-10-27 | 2010-10-19 | Biovail Laboratories International Srl | Quick dissolve compositions and tablets based thereon |
| WO2000025752A1 (en) | 1998-11-02 | 2000-05-11 | Church, Marla, J. | Multiparticulate modified release composition |
| US6270805B1 (en) * | 1998-11-06 | 2001-08-07 | Andrx Pharmaceuticals, Inc. | Two pellet controlled release formulation for water soluble drugs which contains an alkaline metal stearate |
| US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| US20030161879A1 (en) * | 1999-06-29 | 2003-08-28 | Shinji Ohmori | Tablets quickly disintegrating in mouth |
| US6284270B1 (en) * | 1999-08-04 | 2001-09-04 | Drugtech Corporation | Means for creating a mass having structural integrity |
| US6649888B2 (en) | 1999-09-23 | 2003-11-18 | Codaco, Inc. | Radio frequency (RF) heating system |
| US6227409B1 (en) * | 1999-10-25 | 2001-05-08 | Dresser Equipment Group, Inc. | Fluid flow system and method with selective flow rate measurement |
| US6258381B1 (en) * | 2000-02-11 | 2001-07-10 | Mcneil-Ppc, Inc. | Tablet and process for making the same |
| US6277409B1 (en) * | 2000-02-11 | 2001-08-21 | Mcneil-Ppc, Inc. | Protective coating for tablet |
| US6499984B1 (en) * | 2000-05-22 | 2002-12-31 | Warner-Lambert Company | Continuous production of pharmaceutical granulation |
| DE10029201A1 (de) * | 2000-06-19 | 2001-12-20 | Basf Ag | Verfahren zur Herstellung fester oraler Darreichungsformen mit retardierender Wirkstoffreisetzung |
| ATE522211T1 (de) * | 2000-09-20 | 2011-09-15 | Jagotec Ag | Stabilisierte fibrat-mikropartikel |
| ATE431136T1 (de) | 2000-09-22 | 2009-05-15 | Dainippon Sumitomo Pharma Co | Orale zubereitungen mit vorteilhaften zerfallseigenschaften |
| IN192750B (es) | 2000-12-15 | 2004-05-15 | Ranbaxy Lab Ltd | |
| US6814978B2 (en) * | 2000-12-29 | 2004-11-09 | Mcneil-Ppc, Inc. | Process for preparing a soft tablet |
| DE60223659T2 (de) | 2001-03-23 | 2008-10-30 | Gumlink A/S | Einstufiges verfahren zur herstellung von kaugummi |
| GB0110846D0 (en) * | 2001-05-02 | 2001-06-27 | Phoqus Ltd | Tablets with coloured patterns |
| KR100899643B1 (ko) | 2001-09-26 | 2009-05-27 | 가부시키가이샤산와카가쿠켄큐쇼 | 복수의 핵을 갖는 성형품의 제조방법 및 제조장치 |
| US7323192B2 (en) * | 2001-09-28 | 2008-01-29 | Mcneil-Ppc, Inc. | Immediate release tablet |
| CN1596104A (zh) | 2001-09-28 | 2005-03-16 | 麦克内尔-Ppc股份有限公司 | 改进的释放剂型 |
| US20030228368A1 (en) | 2001-09-28 | 2003-12-11 | David Wynn | Edible solid composition and dosage form |
| US6767200B2 (en) * | 2001-09-28 | 2004-07-27 | Mcneil-Ppc, Inc. | Systems, methods and apparatuses for manufacturing dosage forms |
| EA012329B1 (ru) | 2002-01-16 | 2009-08-28 | Бёрингер Ингельхайм Фарма Гмбх Унд Ко. Кг | Способ получения практически аморфного телмисартана |
| WO2003061399A1 (en) | 2002-01-25 | 2003-07-31 | De Abhijit | Chewing gum composition and a process for preparing the same |
| US7993674B2 (en) * | 2002-02-13 | 2011-08-09 | Weibel Michael K | Drug dose-form and method of manufacture |
| US6753009B2 (en) * | 2002-03-13 | 2004-06-22 | Mcneil-Ppc, Inc. | Soft tablet containing high molecular weight polyethylene oxide |
| GB0208587D0 (en) | 2002-04-13 | 2002-05-22 | Stanelco Fibre Optics Ltd | Capsules |
| WO2003101431A1 (en) | 2002-06-04 | 2003-12-11 | J.B. Chemicals & Pharmaceuticals Ltd. | Pharmaceutical composition for controlled drug delivery system |
| US7070825B2 (en) | 2002-09-10 | 2006-07-04 | Abbott Laboratories | Infant formula |
| US7807197B2 (en) * | 2002-09-28 | 2010-10-05 | Mcneil-Ppc, Inc. | Composite dosage forms having an inlaid portion |
| DE10253479A1 (de) | 2002-11-16 | 2004-06-03 | Henkel Kgaa | Befüllte Muldentabletten und Verfahren zu ihrer Herstellung II |
| WO2004047810A1 (en) * | 2002-11-25 | 2004-06-10 | Purdue Research Foundation | Mannose-based fast dissolving tablets |
| DK1599186T3 (da) | 2003-02-24 | 2013-07-08 | Pharmaceutical Productions Inc | System til administration af transmukalt lægemiddel |
| CA2524806C (en) | 2003-05-07 | 2011-07-12 | Akina, Inc. | Highly plastic granules for making fast melting tablets |
| GB0322358D0 (en) | 2003-09-24 | 2003-10-22 | Bioprogress Technology Ltd | Improvements in powder compaction and enrobing |
| WO2006127618A2 (en) | 2005-05-23 | 2006-11-30 | Cadbury Adams Usa Llc | Compressible gum based delivery systems for the release of ingredients |
| DE102004008804A1 (de) | 2004-02-20 | 2005-09-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Mehrschichttablette |
| US20070196477A1 (en) * | 2004-04-30 | 2007-08-23 | Withiam Michael C | Rapidly dissolving tablets comprising low surface area calcium phosphates |
| US20060034927A1 (en) * | 2004-08-04 | 2006-02-16 | Gemma Casadevall | Means of delivering drugs in an ascending zero order release pattern |
| EP1632135A1 (en) | 2004-08-18 | 2006-03-08 | Nestec S.A. | Inert, glassy matrices for the stabilization of aroma in soluble coffee |
| DE102004052308B4 (de) | 2004-10-12 | 2013-04-04 | Divapharma-Knufinke Arzneimittelwerk Gmbh | Octenidinhaltige Lutschtabletten gegen entzündliche Erkrankungen des Mund- und Rachenraums |
| TWI354559B (en) | 2004-12-27 | 2011-12-21 | Yaizu Suisankagaku Ind Co Ltd | Oral disintegrative n-acetylglucosamine tablet and |
| ES2380952T3 (es) * | 2005-10-11 | 2012-05-21 | Bayer Consumer Care Ag | Mezcla de sales de hierro y cobre que enmascaran el sabor metálico. |
| US20070184111A1 (en) | 2006-02-03 | 2007-08-09 | Pharmavite Llc | Hybrid tablet |
| KR20090029710A (ko) | 2006-05-02 | 2009-03-23 | 파나세아 바이오테크 리미티드 | 경점막 조성물 |
| US20070286900A1 (en) | 2006-06-09 | 2007-12-13 | Catherine Herry | Low dose tablets of opioid analgesics and preparation process |
| WO2008005318A2 (en) | 2006-06-29 | 2008-01-10 | Capricorn Pharma Inc. | Chewy products and methods for making the same |
| DK2046300T3 (da) | 2006-08-04 | 2010-07-26 | Ethypharm Sa | Oralt desintegrerende multilagstablet |
| US20080286340A1 (en) * | 2007-05-16 | 2008-11-20 | Sven-Borje Andersson | Buffered nicotine containing products |
| CN101686942B (zh) | 2007-06-27 | 2012-09-26 | 韩美药品株式会社 | 用于快速制备用于口服的崩解剂的方法及其产品 |
| TWI547282B (zh) | 2007-07-02 | 2016-09-01 | 愛戴爾製藥股份有限公司 | 樂命達之口服分解錠劑組合物 |
| US20090060983A1 (en) * | 2007-08-30 | 2009-03-05 | Bunick Frank J | Method And Composition For Making An Orally Disintegrating Dosage Form |
| BRPI0816890A2 (pt) | 2007-09-18 | 2015-03-24 | Niconovum Ab | Composição de goma de mascar, uso de uma combinação de nicotina-celulose, maltitol e uma base de goma, e, método para a preparação de uma composição de goma de mascar |
| RU2482839C2 (ru) | 2007-10-31 | 2013-05-27 | МакНЕЙЛС-ППС, ИНК. | Распадающаяся в полости рта лекарственная форма |
| DK2229158T3 (en) | 2007-12-20 | 2016-12-12 | Fertin Pharma As | Compressed chewing gum tablet |
| CN102119034B (zh) | 2008-06-13 | 2013-05-22 | 大日本住友制药株式会社 | 在口腔中快速崩解的片剂和制备其的方法 |
| GB0821186D0 (en) | 2008-11-19 | 2008-12-24 | Intrinsiq Materials Global Ltd | Gum compositions |
| US8343533B2 (en) | 2009-09-24 | 2013-01-01 | Mcneil-Ppc, Inc. | Manufacture of lozenge product with radiofrequency |
| US8313768B2 (en) | 2009-09-24 | 2012-11-20 | Mcneil-Ppc, Inc. | Manufacture of tablet having immediate release region and sustained release region |
| WO2012039789A1 (en) | 2010-09-22 | 2012-03-29 | Mcneil-Ppc, Inc. | Manufacture of variable density dosage forms utilizing radiofrequency energy |
-
2008
- 2008-10-29 RU RU2010121887/15A patent/RU2482839C2/ru active
- 2008-10-29 BR BRPI0819231A patent/BRPI0819231B8/pt not_active IP Right Cessation
- 2008-10-29 US US12/260,151 patent/US20090110716A1/en not_active Abandoned
- 2008-10-29 KR KR1020107012013A patent/KR101560176B1/ko not_active Expired - Fee Related
- 2008-10-29 MX MX2010004897A patent/MX2010004897A/es not_active Application Discontinuation
- 2008-10-29 AU AU2008318851A patent/AU2008318851B2/en not_active Ceased
- 2008-10-29 CN CN2008801145725A patent/CN101842085B/zh not_active Expired - Fee Related
- 2008-10-29 WO PCT/US2008/081496 patent/WO2009058798A2/en not_active Ceased
- 2008-10-29 CA CA2704209A patent/CA2704209C/en not_active Expired - Fee Related
- 2008-10-29 ES ES08844404.7T patent/ES2633449T3/es active Active
- 2008-10-29 EP EP08844404.7A patent/EP2217213B1/en not_active Not-in-force
- 2008-10-30 AR ARP080104761A patent/AR069128A1/es unknown
-
2009
- 2009-09-24 US US12/566,096 patent/US20100016348A1/en not_active Abandoned
- 2009-09-24 US US12/566,078 patent/US8968769B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2217213B1 (en) | 2017-05-24 |
| CN101842085B (zh) | 2013-01-30 |
| KR20100096120A (ko) | 2010-09-01 |
| KR101560176B1 (ko) | 2015-10-14 |
| US20090110716A1 (en) | 2009-04-30 |
| ES2633449T3 (es) | 2017-09-21 |
| CA2704209C (en) | 2017-02-28 |
| EP2217213A2 (en) | 2010-08-18 |
| US20100016451A1 (en) | 2010-01-21 |
| HK1147202A1 (en) | 2011-08-05 |
| MX2010004897A (es) | 2010-05-19 |
| US8968769B2 (en) | 2015-03-03 |
| AU2008318851A1 (en) | 2009-05-07 |
| CA2704209A1 (en) | 2009-05-07 |
| WO2009058798A3 (en) | 2009-08-27 |
| US20100016348A1 (en) | 2010-01-21 |
| RU2482839C2 (ru) | 2013-05-27 |
| WO2009058798A2 (en) | 2009-05-07 |
| BRPI0819231B1 (pt) | 2019-04-30 |
| BRPI0819231B8 (pt) | 2021-05-25 |
| RU2010121887A (ru) | 2011-12-10 |
| CN101842085A (zh) | 2010-09-22 |
| BRPI0819231A2 (pt) | 2015-05-05 |
| AU2008318851B2 (en) | 2014-04-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR069128A1 (es) | Forma de dosificacion que se desintegra oralmente y proceso de preparacion | |
| ES2645255T3 (es) | Comprimidos orodispersables | |
| NZ598993A (en) | Multi-portion intra-oral dosage form with organoleptic properties | |
| AR079175A1 (es) | Comprimidos y composiciones farmaceuticas comprimibles recubiertos, metodos de fabricacion y metodo para tratar una enfermedad | |
| EP2797587B1 (en) | Highly robust fast-disintegrating tablet and process for manufacturing the same | |
| JP6717902B2 (ja) | シクロベンザプリン塩酸塩の共融製剤 | |
| JP2014509645A5 (es) | ||
| CO5130019A1 (es) | Tabletas masticables suaves comprimidas y de forma convexa y proceso para su preparacion | |
| TWI354559B (en) | Oral disintegrative n-acetylglucosamine tablet and | |
| BRPI0709909A2 (pt) | tabletes de desintegraÇço oral | |
| AR076864A1 (es) | Procedimiento y composicion para mejorar la absorcion de agentes terapeuticos | |
| ES2982524T3 (es) | Comprimido de disgregación por vía oral | |
| JP6049624B2 (ja) | 苦味のある薬物のための経口用医薬フィルム製剤 | |
| AR073365A1 (es) | Preparacion farmaceutica solida de liberacion sostenida | |
| ES2228046T3 (es) | Agente anticatarral que contiene isomalta como principio activo. | |
| BR0114897A (pt) | Preparação farmacêutica hidrofìlica contendo nateglinida, e, método para a preparação da mesma | |
| RU2014130743A (ru) | Таблетки и средства с сухим покрытием | |
| JPH10167958A (ja) | ロキソプロフェンナトリウム類を含有する口腔内速溶性製剤及びその製造方法 | |
| JP2015537019A5 (es) | ||
| PT1878426E (pt) | Preparação granulada contendo um composto de biguanida | |
| IT201900015192A1 (it) | Formulazioni edibili a base di principi attivi e arginina | |
| JP6517575B2 (ja) | 積層錠剤 | |
| KR20140065862A (ko) | 발포성 속붕해성 이매티닙 제제 | |
| CN107951034B (zh) | 维生素泡腾制剂及其制备方法 | |
| RU2009131757A (ru) | Оксалиплатиновая фармацевтическая композиция с буфером на основе сахарного спирта |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |