NO981817L - Indolin-2-on-derivater, fremgangsmÕte for fremstilling av dem og farmas÷ytiske blandinger inneholdende dem - Google Patents

Indolin-2-on-derivater, fremgangsmÕte for fremstilling av dem og farmas÷ytiske blandinger inneholdende dem

Info

Publication number: NO981817L
Authority: NO; Norway
Prior art keywords: indolin; derivatives; preparation; pharmaceutical compositions; compositions containing
Prior art date: 1995-10-24

Application number

NO981817A

Other languages

English (en)

Other versions

NO981817D0 (no

NO310974B1 (no

Inventor

Lo C Foulon

Georges Garcia

Claudine Serradeil-Le Gal

Gurard Valette

Original Assignee

Sanofi Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-10-24

Filing date

1998-04-23

Publication date

1998-04-23

1998-04-23 Application filed by Sanofi Sa filed Critical Sanofi Sa

1998-04-23 Publication of NO981817L publication Critical patent/NO981817L/no

1998-04-23 Publication of NO981817D0 publication Critical patent/NO981817D0/no

2001-09-24 Publication of NO310974B1 publication Critical patent/NO310974B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
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- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/96—Spiro-condensed ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Diabetes (AREA)
Biomedical Technology (AREA)
Ophthalmology & Optometry (AREA)
Cardiology (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Psychiatry (AREA)
Endocrinology (AREA)
Addiction (AREA)
Urology & Nephrology (AREA)
Obesity (AREA)
Hospice & Palliative Care (AREA)
Gastroenterology & Hepatology (AREA)
Vascular Medicine (AREA)
Pain & Pain Management (AREA)
Reproductive Health (AREA)
Emergency Medicine (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

NO19981817A 1995-10-24 1998-04-23 Indolin-2-on-derivater, anvendelse derav, fremgangsmate for fremstilling av dem og farmasoytiske preparater inneholdende dem NO310974B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9512533A FR2740136B1 (fr)	1995-10-24	1995-10-24	Derives d'indolin-2-one, procede pour leur preparation et les compositions pharmaceutiques les contenant
PCT/FR1996/001666 WO1997015556A1 (fr)	1995-10-24	1996-10-24	Derives 3-spiro-indolin-2-one comme ligands des recepteurs de la vasopressine et/ou de l'ocytocine

Publications (3)

Publication Number	Publication Date
NO981817L true NO981817L (no)	1998-04-23
NO981817D0 NO981817D0 (no)	1998-04-23
NO310974B1 NO310974B1 (no)	2001-09-24

Family

ID=9483867

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19981817A NO310974B1 (no)	1995-10-24	1998-04-23	Indolin-2-on-derivater, anvendelse derav, fremgangsmate for fremstilling av dem og farmasoytiske preparater inneholdende dem

Country Status (30)

Country	Link
US (2)	US5994350A (no)
EP (1)	EP0873309B1 (no)
JP (2)	JP3274471B2 (no)
KR (1)	KR100298925B1 (no)
CN (1)	CN1106384C (no)
AR (1)	AR004225A1 (no)
AT (1)	ATE229940T1 (no)
AU (1)	AU715841B2 (no)
BR (1)	BR9611198A (no)
CZ (1)	CZ295585B6 (no)
DE (1)	DE69625517T2 (no)
DK (1)	DK0873309T3 (no)
EE (1)	EE04433B1 (no)
ES (1)	ES2191769T3 (no)
FR (1)	FR2740136B1 (no)
HU (1)	HUP9900331A3 (no)
IL (1)	IL124002A (no)
IN (1)	IN185328B (no)
IS (1)	IS1949B (no)
MY (1)	MY115864A (no)
NO (1)	NO310974B1 (no)
NZ (1)	NZ320352A (no)
PL (1)	PL187093B1 (no)
RU (1)	RU2167864C2 (no)
SK (1)	SK284546B6 (no)
TR (1)	TR199800719T2 (no)
TW (1)	TW474917B (no)
UA (1)	UA59345C2 (no)
WO (1)	WO1997015556A1 (no)
ZA (1)	ZA968945B (no)

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FR2757157B1 (fr) *	1996-12-13	1999-12-31	Sanofi Sa	Derives d'indolin-2-one, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2775598A1 (fr) *	1998-03-06	1999-09-10	Sanofi Sa	Compositions pharmaceutiques contenant en association un antagoniste selectif des recepteurs v1a de l'arginine-vasopressine et un antagoniste selectif des recepteur v2 de l'arginine-vasopressine
FR2778103A1 (fr) *	1998-04-29	1999-11-05	Sanofi Sa	Compositions pharmaceutiques contenant en association un antagoniste v1a de l'arginine-vasopressine et un antagoniste des recepteurs at1 de l'angiotensine ii
HU225150B1 (en) *	1999-07-15	2006-07-28	Sanofi Aventis	Novel process for producing 2-methoxy-4-(t-butylaminocarbonyl)-benzenesulfonyl chloride
HUP9902376A3 (en) *	1999-07-15	2002-11-28	Sanofi Aventis	Process for producing n-(1,1-dimethyl)-4-[[s'-ethoxi-4-cis-[2-(4-morpholino)-ethoxi]-2'-oxospiro[cyclohexane-1,3'-[3h]indole]-1'(2'h)yl]-sulfonyl]-3-methoxybenzamide and its salts
HUP9902374A3 (en) *	1999-07-15	2002-11-28	Sanofi Aventis	Process for producing spiro[(4-cyclohexanone)-[3h]indol-2'[1'h]-on derivatives and intermediates
HU225703B1 (en) *	1999-07-15	2007-06-28	Sanofi Aventis	Process for producing spiro[cis-4-(betha-hydroxy-ethyloxi)-cyclohexane-[3h]indole]-2'[1'h]-one derivatives
US20030103983A1 (en) *	2002-05-09	2003-06-05	Pressler Milton Lethan	Ace inhibitor-vasopressin antagonist combinations
CA2425892A1 (en) *	2000-11-28	2003-04-11	Hiroyuki Koshio	1,4,5,6-tetrahydroimidazo[4,5-d]diazepine derivative or salt thereof
WO2002047679A2 (en) *	2000-12-15	2002-06-20	Emory University	Nonpeptide agonists and antagonists of vasopressin receptors
AU2002247127A1 (en) *	2001-02-14	2002-08-28	Duke University	Therapy for cerebral vasospasm
DE60204154T2 (de) *	2001-07-31	2006-01-19	Sanofi-Aventis	Verfahren zur herstellung von 3 spiro'cyclohexan-1,3'-'3h!indolin-2'-on!derivaten
US7517899B2 (en)	2004-03-30	2009-04-14	Wyeth	Phenylaminopropanol derivatives and methods of their use
US7414052B2 (en)	2004-03-30	2008-08-19	Wyeth	Phenylaminopropanol derivatives and methods of their use
ATE493973T1 (de)	2004-06-04	2011-01-15	Teva Pharma	Irbesartan enthaltende pharmazeutische zusammensetzung
FR2874921B1 (fr) *	2004-09-09	2006-10-20	Sanofi Aventis Sa	Derives de 3-spiro-indolin-2-one, leur preparation et leur application en therapeutique
FR2874920B1 (fr) *	2004-09-09	2006-10-20	Sanofi Aventis Sa	Derives de 3-spiro-indolin-2-one comme ligand des recepteurs de la vasopressine
BRPI0519013A2 (pt) *	2004-12-13	2009-11-03	Lilly Co Eli	composto ou esteroisÈmeros únicos, misturas de esteroisÈmeros, sais, tautÈmeros ou pró-drogas destes farmaceuticamente aceitáveis, composição farmacêutica, e, uso de um composto
EP1831197A2 (de) *	2004-12-31	2007-09-12	Abbott GmbH & Co. KG	Substituierte oxindol-derivate, diese enthaltende arzneimittel und deren verwendung
DE102005014936A1 (de) *	2005-03-24	2006-12-14	Abbott Gmbh & Co. Kg	Substituierte Oxindol-Derivate, diese enthaltende Arzneimittel und deren Verwendung
AR053710A1 (es) *	2005-04-11	2007-05-16	Xenon Pharmaceuticals Inc	Compuestos espiroheterociclicos y sus usos como agentes terapeuticos
MY158766A (en) *	2005-04-11	2016-11-15	Xenon Pharmaceuticals Inc	Spiro-oxindole compounds and their uses as therapeutic agents
AR056317A1 (es) *	2005-04-20	2007-10-03	Xenon Pharmaceuticals Inc	Compuestos de oxindol y composicion farmaceutica
US7351706B2 (en) *	2006-01-05	2008-04-01	Hoffmann-La Roche Inc.	Indol-3-yl-carbonyl-spiro-piperidine derivatives
RU2009117642A (ru)	2006-10-12	2010-11-20	Ксенон Фармасьютикалз Инк. (Ca)	Применение спирооксиндоловых соединений в качестве терапевтических средств
US20110294842A9 (en) *	2006-10-12	2011-12-01	Xenon Pharmaceuticals Inc.	Spiro (furo [3, 2-c] pyridine-3-3' -indol) -2' (1'h)-one derivatives and related compounds for the treatment of sodium-channel mediated diseases, such as pain
CA2666136A1 (en) *	2006-10-12	2008-04-17	Xenon Pharmaceuticals Inc.	Tricyclic spiro-oxindole derivatives and their uses as therapeutic agents
FR2927625B1 (fr)	2008-02-19	2010-03-12	Sanofi Aventis	Nouveaux derives de 3-aminoalkyl-1,3-dihydro-2h-indol-2-one, leur preparation et leur application en therapeutique
US7723372B2 (en) *	2008-03-19	2010-05-25	Hoffman-La Roche Inc.	Spiroindolinone derivatives
FR2930249B1 (fr)	2008-04-21	2010-05-14	Sanofi Aventis	Nouveaux derives de 3-aminoalkyl-1,3-dihydro-2h-indol-2-one, leur preparation et leur application en therapeutique.
JP5570172B2 (ja) *	2008-10-08	2014-08-13	持田製薬株式会社	喫煙による循環機能不全の予防／改善または治療剤
US8101647B2 (en)	2008-10-17	2012-01-24	Xenon Pharmaceuticals Inc.	Spiro-oxindole compounds and their use as therapeutic agents
HRP20150882T1 (hr)	2008-10-17	2015-09-25	Xenon Pharmaceuticals Inc.	Spirooksindolski spojevi i njihova upotreba kao terapijska sredstva
AR077252A1 (es)	2009-06-29	2011-08-10	Xenon Pharmaceuticals Inc	Enantiomeros de compuestos de espirooxindol y sus usos como agentes terapeuticos
WO2011047173A2 (en) *	2009-10-14	2011-04-21	Xenon Pharmaceuticals Inc.	Pharmaceutical compositions for oral administration
NZ599334A (en)	2009-10-14	2014-03-28	Xenon Pharmaceuticals Inc	Synthetic methods for spiro-oxindole compounds
US8088815B2 (en)	2009-12-02	2012-01-03	Hoffman-La Roche Inc.	Spiroindolinone pyrrolidines
US8288431B2 (en)	2010-02-17	2012-10-16	Hoffmann-La Roche Inc.	Substituted spiroindolinones
CN102946859B (zh)	2010-02-26	2016-03-02	泽农医药公司	用于局部给药的螺-羟吲哚化合物的药物组合物及其作为治疗剂的用途
US8217044B2 (en)	2010-04-28	2012-07-10	Hoffmann-La Roche Inc.	Spiroindolinone pyrrolidines
MD4202C1 (ro) *	2012-03-21	2013-09-30	Институт Химии Академии Наук Молдовы	Procedeu de obţinere a derivaţilor carbometoxi ai spiro[ciclopropan-oxindolilor]
MD4201C1 (ro) *	2012-03-21	2013-09-30	Институт Химии Академии Наук Молдовы	Procedeu de obţinere a derivaţilor carbonitrilici ai spiro[ciclopropan-oxindolilor]
CN105143225A (zh) *	2013-03-08	2015-12-09	沃克哈特有限公司	一种制备(2s,5r)-7-氧代-6-磺酰氧基-2-[((3r)-哌啶-3-羰基)-肼基羰基]-1,6-二氮杂-双环[3.2.1]辛烷的方法
AR103636A1 (es)	2015-02-05	2017-05-24	Teva Pharmaceuticals Int Gmbh	Métodos de tratamiento de neuralgia postherpética con una formulación tópica de un compuesto de espiro-oxindol
HU231206B1 (hu)	2017-12-15	2021-10-28	Richter Gedeon Nyrt.	Triazolobenzazepinek
TW201938171A (zh)	2017-12-15	2019-10-01	匈牙利商羅特格登公司	作為血管升壓素Ｖ１ａ受體拮抗劑之三環化合物

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Publication number	Priority date	Publication date	Assignee	Title
DE3818830A1 (de) *	1988-06-03	1989-12-14	Boehringer Mannheim Gmbh	Bicyclische carboxamide, verfahren zu ihrer herstellung, deren vorstufen, und diese verbindungen enthaltende arzneimittel
US5686624A (en) *	1992-01-30	1997-11-11	Sanofi	1-benzenesulfonyl-1,3-dihydro-indol-2-one derivatives, their preparation and pharmaceutical compositions in which they are present
FR2686878B1 (fr) *	1992-01-30	1995-06-30	Sanofi Elf	Derives du n-sulfonyl oxo-2 indole, leur preparation, les compositions pharmaceutiques en contenant.
FR2708605A1 (fr) *	1993-07-30	1995-02-10	Sanofi Sa	Dérivés du N-sulfonylindol-2-one, leur préparation, les compositions pharmaceutiques en contenant.
US5663431A (en) *	1992-01-30	1997-09-02	Sanofi	1-benzenesulfonyl-1,3-dihydro-indol-2-one derivatives, their preparation and pharmaceutical compositions in which they are present
FR2708606B1 (fr) *	1993-07-30	1995-10-27	Sanofi Sa	Dérivés du N-phénylalkylindol-2-one, leur préparation, les compositions pharmaceutiques en contenant.

1995
- 1995-10-24 FR FR9512533A patent/FR2740136B1/fr not_active Expired - Fee Related
1996
- 1996-10-22 TW TW085112955A patent/TW474917B/zh not_active IP Right Cessation
- 1996-10-23 IN IN2288DE1996 patent/IN185328B/en unknown
- 1996-10-23 MY MYPI96004404A patent/MY115864A/en unknown
- 1996-10-23 AR ARP960104863A patent/AR004225A1/es active IP Right Grant
- 1996-10-24 SK SK490-98A patent/SK284546B6/sk not_active IP Right Cessation
- 1996-10-24 US US09/051,900 patent/US5994350A/en not_active Expired - Lifetime
- 1996-10-24 IL IL12400296A patent/IL124002A/en not_active IP Right Cessation
- 1996-10-24 CZ CZ19981267A patent/CZ295585B6/cs not_active IP Right Cessation
- 1996-10-24 TR TR1998/00719T patent/TR199800719T2/xx unknown
- 1996-10-24 ZA ZA968945A patent/ZA968945B/xx unknown
- 1996-10-24 DK DK96934967T patent/DK0873309T3/da active
- 1996-10-24 BR BR9611198A patent/BR9611198A/pt not_active IP Right Cessation
- 1996-10-24 AU AU73080/96A patent/AU715841B2/en not_active Ceased
- 1996-10-24 PL PL96326555A patent/PL187093B1/pl not_active IP Right Cessation
- 1996-10-24 AT AT96934967T patent/ATE229940T1/de active
- 1996-10-24 WO PCT/FR1996/001666 patent/WO1997015556A1/fr not_active Ceased
- 1996-10-24 EE EE9800151A patent/EE04433B1/xx not_active IP Right Cessation
- 1996-10-24 DE DE69625517T patent/DE69625517T2/de not_active Expired - Lifetime
- 1996-10-24 JP JP51636397A patent/JP3274471B2/ja not_active Expired - Fee Related
- 1996-10-24 ES ES96934967T patent/ES2191769T3/es not_active Expired - Lifetime
- 1996-10-24 UA UA98042064A patent/UA59345C2/uk unknown
- 1996-10-24 EP EP96934967A patent/EP0873309B1/fr not_active Expired - Lifetime
- 1996-10-24 NZ NZ320352A patent/NZ320352A/xx not_active IP Right Cessation
- 1996-10-24 CN CN96198579A patent/CN1106384C/zh not_active Expired - Fee Related
- 1996-10-24 HU HU9900331A patent/HUP9900331A3/hu unknown
- 1996-10-24 KR KR1019980702996A patent/KR100298925B1/ko not_active Expired - Fee Related
- 1996-10-24 RU RU98109945/04A patent/RU2167864C2/ru not_active IP Right Cessation
1998
- 1998-04-14 IS IS4714A patent/IS1949B/is unknown
- 1998-04-23 NO NO19981817A patent/NO310974B1/no not_active IP Right Cessation
1999
- 1999-10-12 US US09/417,190 patent/US6046341A/en not_active Expired - Lifetime
2001
- 2001-03-16 JP JP2001075467A patent/JP2001302631A/ja active Pending

Also Published As

Publication number	Publication date
DE69625517D1 (de)	2003-01-30
CZ126798A3 (cs)	1998-08-12
RU2167864C2 (ru)	2001-05-27
MX9803269A (es)	1998-09-30
CN1202886A (zh)	1998-12-23
SK49098A3 (en)	1998-09-09
FR2740136B1 (fr)	1998-01-09
HUP9900331A3 (en)	1999-11-29
NO981817D0 (no)	1998-04-23
ES2191769T3 (es)	2003-09-16
IS1949B (is)	2004-10-13
AU7308096A (en)	1997-05-15
IL124002A (en)	2002-11-10
JP3274471B2 (ja)	2002-04-15
IN185328B (no)	2000-12-30
HUP9900331A2 (hu)	1999-05-28
CN1106384C (zh)	2003-04-23
KR19990067056A (ko)	1999-08-16
HK1016596A1 (en)	1999-11-05
PL187093B1 (pl)	2004-05-31
ATE229940T1 (de)	2003-01-15
EE9800151A (et)	1998-12-15
WO1997015556A1 (fr)	1997-05-01
US6046341A (en)	2000-04-04
DK0873309T3 (da)	2003-03-17
UA59345C2 (uk)	2003-09-15
JP2001302631A (ja)	2001-10-31
FR2740136A1 (fr)	1997-04-25
AU715841B2 (en)	2000-02-10
US5994350A (en)	1999-11-30
DE69625517T2 (de)	2003-09-11
ZA968945B (en)	1997-05-29
AR004225A1 (es)	1998-11-04
NO310974B1 (no)	2001-09-24
EP0873309B1 (fr)	2002-12-18
CZ295585B6 (cs)	2005-08-17
MY115864A (en)	2003-09-30
EP0873309A1 (fr)	1998-10-28
TR199800719T2 (xx)	1998-08-21
KR100298925B1 (ko)	2001-09-06
TW474917B (en)	2002-02-01
IS4714A (is)	1998-04-14
SK284546B6 (sk)	2005-06-02
JPH11509232A (ja)	1999-08-17
NZ320352A (en)	2000-01-28
PL326555A1 (en)	1998-09-28
EE04433B1 (et)	2005-02-15
BR9611198A (pt)	1999-04-06

Publication	Publication Date	Title
NO981817L (no)	1998-04-23	Indolin-2-on-derivater, fremgangsmÕte for fremstilling av dem og farmas÷ytiske blandinger inneholdende dem
HUP9602511A2 (en)	1997-03-28	Aryl-diazinone derivatives, pharmaceutical compositions containing them, and process for producing all these
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DK0477049T3 (da)	2000-04-25	3-amido-pyrazolderivater, fremgangsmåde til deres fremstilling og farmaceutiske præparater indeholdende dem
NO975987D0 (no)	1997-12-19	4-Fenylaminotiazol-derivater, fremgangsmåte for fremstilling av disse og farmasöytiske blandinger inneholdende nevnte derivater
NO974685D0 (no)	1997-10-10	Acetamidderivater, fremgangsmåte for fremstilling av disse, og farmasöytisk preparat inneholdende disse
HUP9901086A3 (en)	2000-03-28	Arylsulfonylaminobenzene derivatives, pharmaceutical compositions containing them and their use for producing pharmaceutical compositions
AU4821096A (en)	1996-10-03	Benzazepine-, benzoxazepine- and benzothiazepine-N-acetic derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0100723A3 (en)	2002-12-28	Indole derivatives, process for producing them and pharmaceutical compositions containing them
NO942835L (no)	1995-01-31	1-benzensulfonyl-1,3-dihydro-2H-benzimidazol-2-on-derivater, fremstilling derav og farmasöytiske blandinger som inneholder dem
HUP9600071A3 (en)	2000-04-28	Indolo-piperidine derivatives, pharmaceutical compositions containing them, process for producing them and their use
HUP9603023A3 (en)	1998-12-28	Substituted (sulfonimidamido)benzoyl-guanidine derivatives, process for producing them and pharmaceutical compositions containing them
IL109703A0 (en)	1994-08-26	Substituted carbazole derivatives, processes for their preparation and pharmaceutical compositions containing them
HUP9600876A3 (en)	2000-04-28	Benzonitril- and -fluoride derivatives, pharmaceutical compositions containing them, process for producing them and their use
HUP9602681A1 (en)	1997-09-29	Hydroxy-pyridinone derivatives, process for producing them and pharmaceutical compositions containing them
HUP9602635A2 (en)	1997-11-28	4-aciloxy-benzenesulfonamide derivatives, process for their preparation and pharmaceutical compositions containing them
HUT76065A (en)	1997-06-30	Indole derivatives, pharmaceutical compositions containing them, process for producing them and their use
NO950537D0 (no)	1995-02-13	Polysubstituerte 3-acylamino-5-fenyl-1,4-benzodiazepin-2-on-derivater, fremgangsmåter for fremstilling derav og farmasöytiske blandinger inneholdende dem
NO955320L (no)	1996-07-01	Substituerte 4-fenyltiazolderivater, fremgangsmåte for fremstilling derav og farmasöytiske blandinger som inneholder dem
GB9617893D0 (en)	1996-10-09	New pharmaceutical derivatives, process for obtaining them and pharmaceutical compositions containing them
HUP9601062A3 (en)	1998-10-28	Chromone derivatives, pharmaceutical compositions containing them and process for their preparation
HU9602640D0 (en)	1996-11-28	Substituted benzoyl-guanidine derivatives, process for producing them and pharmaceutical compositions containing them
HUP0004294A3 (en)	2001-11-28	Indole derivatives, pharmaceutical compositions containing them and process for producing them
HUP0100785A3 (en)	2001-09-28	Indole derivatives, process for producing them and pharmaceutical compositions containing them

Legal Events

Date	Code	Title	Description
2013-05-27	MM1K	Lapsed by not paying the annual fees