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MX2013005169A - Derivados biciclicos sustituidos de carboxamida y urea como ligandos de receptor vanilloide. - Google Patents

Derivados biciclicos sustituidos de carboxamida y urea como ligandos de receptor vanilloide.

Info

Publication number
MX2013005169A
MX2013005169A MX2013005169A MX2013005169A MX2013005169A MX 2013005169 A MX2013005169 A MX 2013005169A MX 2013005169 A MX2013005169 A MX 2013005169A MX 2013005169 A MX2013005169 A MX 2013005169A MX 2013005169 A MX2013005169 A MX 2013005169A
Authority
MX
Mexico
Prior art keywords
urea derivatives
substituted bicyclic
receptor ligands
vanilloid receptor
bicyclic carboxamide
Prior art date
Application number
MX2013005169A
Other languages
English (en)
Inventor
Sven Frormann
Thomas Christoph
Robert Frank
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of MX2013005169A publication Critical patent/MX2013005169A/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Psychology (AREA)
  • Immunology (AREA)
  • Anesthesiology (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)

Abstract

La invención se relaciona con derivados de carboxamida y urea bicíclicos sustituidos, con procedimientos para la preparación de los mismos, con composiciones farmacéuticas que contienen estos compuestos y también con el uso de estos compuestos para preparar composiciones farmacéuticas. (ver Fórmula).
MX2013005169A 2010-11-10 2011-11-09 Derivados biciclicos sustituidos de carboxamida y urea como ligandos de receptor vanilloide. MX2013005169A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10014450 2010-11-10
PCT/EP2011/005630 WO2012062463A1 (en) 2010-11-10 2011-11-09 Substituted bicyclic carboxamide and urea derivatives as vanilloid receptor ligands

Publications (1)

Publication Number Publication Date
MX2013005169A true MX2013005169A (es) 2013-07-05

Family

ID=43642406

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013005169A MX2013005169A (es) 2010-11-10 2011-11-09 Derivados biciclicos sustituidos de carboxamida y urea como ligandos de receptor vanilloide.

Country Status (10)

Country Link
US (1) US20120115893A1 (es)
EP (1) EP2638015A1 (es)
JP (1) JP2013542231A (es)
AR (1) AR083816A1 (es)
AU (1) AU2011328521A1 (es)
BR (1) BR112013010587A2 (es)
CA (1) CA2816804A1 (es)
MX (1) MX2013005169A (es)
TW (1) TW201302712A (es)
WO (1) WO2012062463A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020061315A1 (en) 2018-09-20 2020-03-26 University Of Miami Materials and methods for inducing therapeutic hypothermia in a mammalian subject

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007054480A1 (en) * 2005-11-08 2007-05-18 N.V. Organon 2-(benzimidazol-1-yl)-acetamide biaryl derivatives and their use as inhibitors of the trpv1 receptor
BRPI0713187A2 (pt) * 2006-07-20 2012-10-16 Mehmet Kahraman método de inibir rho-quinase, método de tratamento de doença mediada por rho-quinase, composto e composição farmacêutica
ATE509925T1 (de) * 2006-11-17 2011-06-15 Pfizer Substituierte bicyclocarbonsäureamidverbindungen
ES2640257T3 (es) * 2009-05-07 2017-11-02 Medifron Dbt Inc. Fenilureas y fenilamidas sustituidas como ligandos del receptor vanilloide

Also Published As

Publication number Publication date
US20120115893A1 (en) 2012-05-10
AU2011328521A1 (en) 2013-05-02
CA2816804A1 (en) 2012-05-18
WO2012062463A1 (en) 2012-05-18
JP2013542231A (ja) 2013-11-21
BR112013010587A2 (pt) 2016-08-09
TW201302712A (zh) 2013-01-16
AR083816A1 (es) 2013-03-27
EP2638015A1 (en) 2013-09-18

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