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MX2012000369A - Forma de dosificacion resistente a la manipulacion para opioides sensibles a la oxidacion. - Google Patents

Forma de dosificacion resistente a la manipulacion para opioides sensibles a la oxidacion.

Info

Publication number
MX2012000369A
MX2012000369A MX2012000369A MX2012000369A MX2012000369A MX 2012000369 A MX2012000369 A MX 2012000369A MX 2012000369 A MX2012000369 A MX 2012000369A MX 2012000369 A MX2012000369 A MX 2012000369A MX 2012000369 A MX2012000369 A MX 2012000369A
Authority
MX
Mexico
Prior art keywords
dosage form
oploids
tamper
oxidation
sensitive
Prior art date
Application number
MX2012000369A
Other languages
English (en)
Inventor
Johannes Bartholomaeus
Anja Geissler
Ulrike Bertram
Kornelia Griessmann
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41263602&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2012000369(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of MX2012000369A publication Critical patent/MX2012000369A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/284Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Wrappers (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La invención se refiere a una forma de dosificación farmacéutica termoformada que tiene una resistencia a la ruptura de al menos 300 N, la forma de dosificación comprende: - un opioide (A), - un ácido libre fisiológicamente aceptable (B) en una cantidad de desde 0T001 a 5.0% por peso, con base en el peso total de la forma de dosificación farmacéutica, y - un óxido de polialquileno (C) que tiene un peso de peso molecular promedio MW de al menos 200,000 g/mol.
MX2012000369A 2009-07-22 2010-07-21 Forma de dosificacion resistente a la manipulacion para opioides sensibles a la oxidacion. MX2012000369A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09009480 2009-07-22
PCT/EP2010/004460 WO2011009603A1 (en) 2009-07-22 2010-07-21 Tamper-resistant dosage form for oxidation-sensitive oploids

Publications (1)

Publication Number Publication Date
MX2012000369A true MX2012000369A (es) 2012-02-01

Family

ID=41263602

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2012000369A MX2012000369A (es) 2009-07-22 2010-07-21 Forma de dosificacion resistente a la manipulacion para opioides sensibles a la oxidacion.
MX2012000644A MX2012000644A (es) 2009-07-22 2010-07-21 Forma de dosificacion de oxidacion estabilizada resistente a la manipulacion.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2012000644A MX2012000644A (es) 2009-07-22 2010-07-21 Forma de dosificacion de oxidacion estabilizada resistente a la manipulacion.

Country Status (26)

Country Link
US (7) US20110020451A1 (es)
EP (4) EP2456425B1 (es)
JP (2) JP2012533585A (es)
KR (2) KR101747156B1 (es)
CN (2) CN102639118B (es)
AR (1) AR077420A1 (es)
AU (2) AU2010275754B2 (es)
BR (2) BR112012001466A2 (es)
CA (2) CA2766172C (es)
CL (2) CL2011002969A1 (es)
CO (2) CO6470798A2 (es)
EC (2) ECSP12011590A (es)
ES (3) ES2718688T3 (es)
HK (1) HK1216296A1 (es)
HU (1) HUE042987T2 (es)
IL (3) IL216525A (es)
MX (2) MX2012000369A (es)
NZ (2) NZ596666A (es)
PE (2) PE20120572A1 (es)
PL (2) PL2456424T3 (es)
PT (1) PT2456424E (es)
RU (3) RU2555531C2 (es)
SI (1) SI2456424T1 (es)
TW (1) TWI473628B (es)
WO (2) WO2011009604A1 (es)
ZA (2) ZA201109446B (es)

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