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MX2007001338A - Anticuerpos antagonistas de il-17. - Google Patents

Anticuerpos antagonistas de il-17.

Info

Publication number
MX2007001338A
MX2007001338A MX2007001338A MX2007001338A MX2007001338A MX 2007001338 A MX2007001338 A MX 2007001338A MX 2007001338 A MX2007001338 A MX 2007001338A MX 2007001338 A MX2007001338 A MX 2007001338A MX 2007001338 A MX2007001338 A MX 2007001338A
Authority
MX
Mexico
Prior art keywords
antagonist antibodies
antibody
human
disorder
heavy
Prior art date
Application number
MX2007001338A
Other languages
English (en)
Inventor
Margit Jeschke
Franco E Di Padova
Hermann Gram
Hans Hofstetter
Jean-Michael Rondeau
Wim Van Den Berg
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32982602&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2007001338(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2007001338A publication Critical patent/MX2007001338A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Pain & Pain Management (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Dermatology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Se proporciona una molecula de enlace de IL-17, en particular un anticuerpo para IL-17 humana, mas preferiblemente un anticuerpo humano para IL-17 humana, en donde las regiones hipervariables de las cadenas pesada y ligera tienen secuencias de aminoacidos como se definen, para utilizarse en el tratamiento de una enfermedad o trastorno mediado por IL-17, por ejemplo artritis reumatoide.
MX2007001338A 2004-08-05 2005-08-04 Anticuerpos antagonistas de il-17. MX2007001338A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0417487.6A GB0417487D0 (en) 2004-08-05 2004-08-05 Organic compound
PCT/EP2005/008470 WO2006013107A1 (en) 2004-08-05 2005-08-04 Il-17 antagonistic antibodies

Publications (1)

Publication Number Publication Date
MX2007001338A true MX2007001338A (es) 2008-03-11

Family

ID=32982602

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007001338A MX2007001338A (es) 2004-08-05 2005-08-04 Anticuerpos antagonistas de il-17.

Country Status (40)

Country Link
US (9) US7807155B2 (es)
EP (5) EP2366405B1 (es)
JP (1) JP4682200B2 (es)
KR (2) KR100852523B1 (es)
CN (1) CN101001645B (es)
AR (1) AR050200A1 (es)
AT (1) ATE517924T1 (es)
AU (2) AU2005268857C1 (es)
BE (1) BE2015C041I2 (es)
BR (3) BR122018075556B1 (es)
CA (1) CA2573586C (es)
CY (6) CY1111963T1 (es)
DK (4) DK1776142T6 (es)
EC (1) ECSP077198A (es)
ES (4) ES2536228T3 (es)
FR (1) FR15C0048I2 (es)
GB (1) GB0417487D0 (es)
HK (1) HK1256639A1 (es)
HR (3) HRP20110758T4 (es)
HU (4) HUE038187T2 (es)
IL (1) IL180717A (es)
LT (3) LT2902039T (es)
LU (2) LU92768I2 (es)
MA (1) MA28982B1 (es)
MX (1) MX2007001338A (es)
MY (1) MY144925A (es)
NL (1) NL300749I2 (es)
NO (9) NO336279B1 (es)
NZ (1) NZ552658A (es)
PE (1) PE20060418A1 (es)
PL (4) PL2902039T3 (es)
PT (4) PT2902039T (es)
RU (2) RU2426741C3 (es)
SG (1) SG155186A1 (es)
SI (4) SI2902039T1 (es)
TN (1) TNSN07034A1 (es)
TR (1) TR201808057T4 (es)
TW (1) TWI359153B (es)
WO (1) WO2006013107A1 (es)
ZA (1) ZA200700242B (es)

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NO20171697A1 (no) 2007-03-30
PL2364729T3 (pl) 2014-10-31
DK2366405T3 (en) 2015-05-11
HRP20110758T1 (en) 2011-11-30
NO2015023I2 (no) 2015-10-26
BRPI0513078C1 (pt) 2021-05-25
PL2902039T3 (pl) 2018-09-28
GB0417487D0 (en) 2004-09-08
AU2010201689A1 (en) 2010-05-20
PT2364729E (pt) 2014-09-01
DK1776142T3 (da) 2011-10-31
ES2367440T3 (es) 2011-11-03
ES2487533T3 (es) 2014-08-21
MA28982B1 (fr) 2007-11-01
CY1116256T1 (el) 2017-02-08
US20150152178A1 (en) 2015-06-04
US20250122277A1 (en) 2025-04-17
US20230235038A1 (en) 2023-07-27
HUE025815T2 (en) 2016-04-28
PT1776142E (pt) 2011-10-06
PE20060418A1 (es) 2006-06-15
CA2573586C (en) 2013-06-25
NO336279B1 (no) 2015-07-06
TWI359153B (en) 2012-03-01
AU2005268857B2 (en) 2010-01-28
US10344084B2 (en) 2019-07-09
LTPA2018515I1 (lt) 2018-10-25
AU2010201689B2 (en) 2011-09-29
EP2364729B3 (en) 2015-06-24
LT2902039T (lt) 2018-06-25
BRPI0513078B1 (pt) 2019-02-19
ES2677245T3 (es) 2018-07-31
ZA200700242B (en) 2008-08-27
CY2015030I2 (el) 2017-11-14
KR20070036166A (ko) 2007-04-02
PL1776142T6 (pl) 2016-06-30
PL1776142T4 (pl) 2018-04-30
EP2902039A1 (en) 2015-08-05
NO2015023I1 (no) 2015-11-02
NO337129B1 (no) 2016-01-25
NO348010B1 (no) 2024-06-17
AU2005268857C1 (en) 2012-01-19
LU92768I2 (fr) 2015-11-03
BRPI0513078A (pt) 2008-04-22
SI1776142T1 (sl) 2011-11-30
SG155186A1 (en) 2009-09-30
EP2902039B1 (en) 2018-04-11

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