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UA97084C2 - Пеллета пролонгированного высвобождения, которая содержит прамипексол или его фармацевтически приемлемую соль, ее применение и капсула, которая содержит такие пеллеты - Google Patents

Пеллета пролонгированного высвобождения, которая содержит прамипексол или его фармацевтически приемлемую соль, ее применение и капсула, которая содержит такие пеллеты

Info

Publication number
UA97084C2
UA97084C2 UAA201010396A UAA201010396A UA97084C2 UA 97084 C2 UA97084 C2 UA 97084C2 UA A201010396 A UAA201010396 A UA A201010396A UA A201010396 A UAA201010396 A UA A201010396A UA 97084 C2 UA97084 C2 UA 97084C2
Authority
UA
Ukraine
Prior art keywords
pharmaceutically acceptable
pellets
extended release
manufacturing
pramipexole
Prior art date
Application number
UAA201010396A
Other languages
English (en)
Ukrainian (uk)
Inventor
Томас Фридль
Рольф-Штефан Брикль
Original Assignee
Бьорингер Ингельхайм Интернациональ Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34926162&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA97084(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Бьорингер Ингельхайм Интернациональ Гмбх filed Critical Бьорингер Ингельхайм Интернациональ Гмбх
Publication of UA97084C2 publication Critical patent/UA97084C2/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Изобретение касается пеллеты пролонгированного высвобождения, которая включает ядро, сформированное экструзией из раствора или расплава или гранулирования из расплава прамипексола или его фармацевтически приемлемой соли и инертных наполнителей, и покрытие пролонгированного высвобождения, которое включает смесь от 10 до 85 масс. % зависимого от рН полимера, который образовывает энтеросолюбильное покрытие, и от 15 до 75 масс. % независимого от рН полимера, который набухает в воде, и необязательно дополнительно включает порообразующий компонент.
UAA201010396A 2004-08-13 2005-07-25 Пеллета пролонгированного высвобождения, которая содержит прамипексол или его фармацевтически приемлемую соль, ее применение и капсула, которая содержит такие пеллеты UA97084C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04019249 2004-08-13

Publications (1)

Publication Number Publication Date
UA97084C2 true UA97084C2 (ru) 2011-12-26

Family

ID=34926162

Family Applications (3)

Application Number Title Priority Date Filing Date
UAA201010396A UA97084C2 (ru) 2004-08-13 2005-07-25 Пеллета пролонгированного высвобождения, которая содержит прамипексол или его фармацевтически приемлемую соль, ее применение и капсула, которая содержит такие пеллеты
UAA200702473A UA88477C2 (ru) 2004-08-13 2005-07-25 Композиция пеллеты пролонгированного высвобождения, которая содержит прамипексол или его фармацевтически приемлемую соль, способ ее изготовления и ее применение
UAA200906587A UA95993C2 (ru) 2004-08-13 2005-07-25 Композиция пеллеты пролонгированного высвобождения, которая содержит прамипексол или его фармацевтически приемлемую соль, способ ее изготовления и ее применение

Family Applications After (2)

Application Number Title Priority Date Filing Date
UAA200702473A UA88477C2 (ru) 2004-08-13 2005-07-25 Композиция пеллеты пролонгированного высвобождения, которая содержит прамипексол или его фармацевтически приемлемую соль, способ ее изготовления и ее применение
UAA200906587A UA95993C2 (ru) 2004-08-13 2005-07-25 Композиция пеллеты пролонгированного высвобождения, которая содержит прамипексол или его фармацевтически приемлемую соль, способ ее изготовления и ее применение

Country Status (19)

Country Link
US (3) US20060051419A1 (ru)
EP (3) EP1778201B1 (ru)
JP (1) JP4971159B2 (ru)
KR (2) KR20070050081A (ru)
CN (3) CN101843597A (ru)
AU (1) AU2005271193B2 (ru)
BR (1) BRPI0513848A (ru)
CA (1) CA2576386A1 (ru)
EA (2) EA200700388A1 (ru)
EC (1) ECSP077243A (ru)
EG (1) EG26209A (ru)
IL (1) IL181281A0 (ru)
MX (1) MX2007001850A (ru)
NO (1) NO20070944L (ru)
NZ (1) NZ553645A (ru)
SG (1) SG164375A1 (ru)
UA (3) UA97084C2 (ru)
WO (1) WO2006015943A2 (ru)
ZA (1) ZA200700313B (ru)

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