SMT201600081B - Inibitore di bromodominio di benzodiazepina - Google Patents

Inibitore di bromodominio di benzodiazepina

Info

Publication number: SMT201600081B
Authority: SM; San Marino
Prior art keywords: bromodomyn; benzodiazepine; inhibitor; bromodomyn inhibitor; benzodiazepine bromodomyn
Prior art date: 2009-11-05

Application number

SM201600081T

Other languages

English (en)

Inventor

Romain Luc Marie Gosmini

Olivier Mirguet

Original Assignee

Glaxosmithkline Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-11-05

Filing date

2016-03-22

Publication date

2016-04-29

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42667965&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SMT201600081(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2009-11-05 Priority claimed from GB0919433A external-priority patent/GB0919433D0/en

2010-06-22 Priority claimed from GBGB1010509.6A external-priority patent/GB201010509D0/en

2016-03-22 Application filed by Glaxosmithkline Llc filed Critical Glaxosmithkline Llc

2016-04-29 Publication of SMT201600081B publication Critical patent/SMT201600081B/it

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
- A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

SM201600081T 2009-11-05 2016-03-22 Inibitore di bromodominio di benzodiazepina SMT201600081B (it)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB0919433A GB0919433D0 (en)	2009-11-05	2009-11-05	Novel compounds
GBGB1010509.6A GB201010509D0 (en)	2010-06-22	2010-06-22	Novel compounds
PCT/EP2010/061518 WO2011054553A1 (en)	2009-11-05	2010-08-06	Benzodiazepine bromodomain inhibitor

Publications (1)

Publication Number	Publication Date
SMT201600081B true SMT201600081B (it)	2016-04-29

Family

ID=42667965

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
SM201400024T SMT201400024B (it)	2009-11-05	2014-02-20	Inibitore del bromodominio di benzodiazepine
SM201600081T SMT201600081B (it)	2009-11-05	2016-03-22	Inibitore di bromodominio di benzodiazepina

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
SM201400024T SMT201400024B (it)	2009-11-05	2014-02-20	Inibitore del bromodominio di benzodiazepine

Country Status (33)

Country	Link
US (3)	US9023842B2 (it)
EP (3)	EP2496580B1 (it)
JP (1)	JP5524343B2 (it)
KR (1)	KR101424989B1 (it)
CN (1)	CN102762569B (it)
AU (1)	AU2010314395B2 (it)
BR (1)	BR112012010706A2 (it)
CA (1)	CA2779355C (it)
CL (1)	CL2012001178A1 (it)
CO (1)	CO6540003A2 (it)
CR (1)	CR20120283A (it)
CY (2)	CY1114988T1 (it)
DK (2)	DK2496580T3 (it)
DO (1)	DOP2012000114A (it)
EA (1)	EA020390B1 (it)
ES (3)	ES2652304T3 (it)
HK (1)	HK1220188A1 (it)
HR (2)	HRP20140107T1 (it)
HU (1)	HUE026421T2 (it)
IL (2)	IL219090A0 (it)
MA (1)	MA33803B1 (it)
ME (1)	ME02360B (it)
MX (1)	MX2012005295A (it)
MY (1)	MY160456A (it)
NZ (1)	NZ599258A (it)
PE (1)	PE20121181A1 (it)
PH (1)	PH12012500894A1 (it)
PL (2)	PL2722334T3 (it)
PT (2)	PT2496580E (it)
RS (2)	RS53179B (it)
SI (2)	SI2496580T1 (it)
SM (2)	SMT201400024B (it)
WO (1)	WO2011054553A1 (it)

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* Cited by examiner, † Cited by third party
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Also Published As

Publication number	Publication date
SMT201400024B (it)	2014-07-07
AU2010314395B2 (en)	2015-04-09
EP3037423B1 (en)	2017-09-20
US20150210706A1 (en)	2015-07-30
IL235983B (en)	2018-01-31
HK1175458A1 (en)	2013-07-05
EA201290183A1 (ru)	2012-12-28
US20120220573A1 (en)	2012-08-30
RS53179B (sr)	2014-06-30
JP5524343B2 (ja)	2014-06-18
CR20120283A (es)	2012-08-14
CY1114988T1 (el)	2016-12-14
CA2779355C (en)	2018-01-16
PL2496580T3 (pl)	2014-06-30
SI2722334T1 (sl)	2016-03-31
PT2496580E (pt)	2014-02-21
EP2722334A1 (en)	2014-04-23
PT2722334E (pt)	2016-03-11
MY160456A (en)	2017-03-15
DOP2012000114A (es)	2012-08-15
ME02360B (me)	2016-06-20
SI2496580T1 (sl)	2014-02-28
CO6540003A2 (es)	2012-10-16
US20170197972A1 (en)	2017-07-13
US9023842B2 (en)	2015-05-05
NZ599258A (en)	2014-05-30
HRP20140107T1 (hr)	2014-04-25
IL235983A0 (en)	2015-01-29
AU2010314395A1 (en)	2012-05-24
HK1220188A1 (en)	2017-04-28
EP3037423A1 (en)	2016-06-29
HUE026421T2 (en)	2016-05-30
MX2012005295A (es)	2012-06-19
PL2722334T3 (pl)	2016-06-30
EP2722334B1 (en)	2016-01-13
ES2446647T3 (es)	2014-03-10
ES2652304T3 (es)	2018-02-01
ES2563057T3 (es)	2016-03-10
DK2722334T3 (en)	2016-03-07
KR20120099250A (ko)	2012-09-07
PE20121181A1 (es)	2012-09-13
PH12012500894A1 (en)	2022-03-09
EP2496580B1 (en)	2013-12-11
HK1191012A1 (en)	2014-07-18
IL219090A0 (en)	2012-06-28
DK2496580T3 (da)	2014-02-24
JP2013510107A (ja)	2013-03-21
CN102762569B (zh)	2015-04-01
KR101424989B1 (ko)	2014-07-31
BR112012010706A2 (pt)	2016-03-29
WO2011054553A1 (en)	2011-05-12
CN102762569A (zh)	2012-10-31
CY1117479T1 (el)	2017-04-26
CA2779355A1 (en)	2011-05-12
EP2496580A1 (en)	2012-09-12
CL2012001178A1 (es)	2012-10-05
RS54592B1 (sr)	2016-08-31
EA020390B1 (ru)	2014-10-30
MA33803B1 (fr)	2012-12-03
HRP20160119T1 (hr)	2016-02-26

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DK2246336T3 (da)	2020-07-20	Fibroseinhibitor
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DE112009005462T8 (de)	2013-03-28	Lenkungsssteuervorrichtung
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FI20095754A0 (fi)	2009-07-03	Tuloilmalaite
EP2435048A4 (en)	2013-07-10	RADIOACTIVELY MARKED PDE10 HEMMER
DK2488157T3 (da)	2021-01-25	Forbedrede formuleringer
BRPI1010159A2 (pt)	2016-03-29	bistuti