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PT937083E - Substancia cristalina de cefditoren pivoxil e sua producao - Google Patents

Substancia cristalina de cefditoren pivoxil e sua producao

Info

Publication number
PT937083E
PT937083E PT97940434T PT97940434T PT937083E PT 937083 E PT937083 E PT 937083E PT 97940434 T PT97940434 T PT 97940434T PT 97940434 T PT97940434 T PT 97940434T PT 937083 E PT937083 E PT 937083E
Authority
PT
Portugal
Prior art keywords
crystaline
substance
production
cefditoren pivoxil
pivoxil
Prior art date
Application number
PT97940434T
Other languages
English (en)
Inventor
Tatsuo Watanabe
Yasushi Murai
Katsuharu Iinuma
Kiyoshi Yasui
Masahiro Onodera
Masamichi Sukegawa
Yuichi Yamamoto
Original Assignee
Meiji Seika Kaisha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Seika Kaisha filed Critical Meiji Seika Kaisha
Publication of PT937083E publication Critical patent/PT937083E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Liquid Crystal Substances (AREA)
PT97940434T 1996-09-20 1997-09-19 Substancia cristalina de cefditoren pivoxil e sua producao PT937083E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP24956196 1996-09-20

Publications (1)

Publication Number Publication Date
PT937083E true PT937083E (pt) 2003-08-29

Family

ID=17194838

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97940434T PT937083E (pt) 1996-09-20 1997-09-19 Substancia cristalina de cefditoren pivoxil e sua producao

Country Status (25)

Country Link
US (2) US6294669B1 (pt)
EP (1) EP0937083B1 (pt)
JP (1) JP3403206B2 (pt)
KR (1) KR100441907B1 (pt)
CN (1) CN1116299C (pt)
AR (1) AR008483A1 (pt)
AT (1) ATE238310T1 (pt)
AU (1) AU714735B2 (pt)
BR (1) BR9712072A (pt)
CA (1) CA2265686C (pt)
CZ (1) CZ295199B6 (pt)
DE (1) DE69721290T2 (pt)
EA (1) EA001526B1 (pt)
ES (1) ES2198593T3 (pt)
HU (1) HU224196B1 (pt)
ID (1) ID22064A (pt)
IL (1) IL129016A (pt)
NZ (1) NZ334883A (pt)
PL (1) PL189548B1 (pt)
PT (1) PT937083E (pt)
RO (1) RO120196B1 (pt)
SK (1) SK284973B6 (pt)
TR (1) TR199900614T2 (pt)
UA (1) UA55426C2 (pt)
WO (1) WO1998012200A1 (pt)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL189548B1 (pl) * 1996-09-20 2005-08-31 Meiji Seika Kaisha Krystaliczny cefditoren piwoksylu i sposób jego wytwarzania
TR200001903T2 (tr) * 1998-01-07 2000-11-21 Meiji Seika Kaisha, Ltd. Kristalografik açıdan kararlı, şekilsiz sefalosporin bileşimleri ve bunların üretilmesine ilişkin işlem.
HK1049656A1 (zh) * 1999-10-08 2003-05-23 Smithkline Beecham Corporation Fab i抑制剂
HU226640B1 (en) * 1999-10-18 2009-05-28 Egis Gyogyszergyar Nyilvanosan Process for producing amorphous atorvastatin calcium salt
JP2001131071A (ja) * 1999-10-29 2001-05-15 Meiji Seika Kaisha Ltd 非晶質および非晶質を含有する医薬組成物
US7049310B2 (en) * 2001-04-06 2006-05-23 Affinium Pharmaceuticals, Inc. Fab I inhibitors
JP2006500364A (ja) * 2002-08-16 2006-01-05 イムノージェン インコーポレーテッド 高い反応性と溶解度を有する架橋剤および小分子薬物の標的化送達用コンジュゲートの調製におけるそれらの使用
PT1555024E (pt) * 2002-10-02 2010-11-18 Meiji Seika Kaisha Composição medicinal antibacteriana com absorção oral melhorada
AU2003276525A1 (en) * 2002-11-15 2004-06-15 Orchid Chemicals And Pharmaceuticals Ltd Novel amorphous hydrate of a cephalosporin antibiotic
US7790709B2 (en) 2002-12-06 2010-09-07 Affinium Pharmaceuticals, Inc. Heterocyclic compounds, methods of making them and their use in therapy
DE602004016831D1 (de) * 2003-03-17 2008-11-13 Affinium Pharm Inc Pharmazeutische zusammensetzungen inhibitoren von fab i und weitere antibiotika enthaltend
DE602004022643D1 (de) * 2003-03-27 2009-10-01 Basilea Pharmaceutica Ag Cephalosporin in kristalliner form
US8088387B2 (en) * 2003-10-10 2012-01-03 Immunogen Inc. Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
EP1660505A2 (en) * 2003-08-14 2006-05-31 Ranbaxy Laboratories Limited Process for selective preparation of z-isomer of cefditoren and pharmaceutically acceptable salts and esters thereof
ATE539738T1 (de) 2003-10-08 2012-01-15 Meiji Seika Pharma Co Ltd Nichtkristalline antibakterielle zusammensetzung mit cefditoren-pivoxil
JP2007510709A (ja) * 2003-11-07 2007-04-26 ランバクシー ラボラトリーズ リミテッド 高純度３−（２−置換ビニル）セファロスポリンの製法
JP2005162696A (ja) * 2003-12-04 2005-06-23 Nichiko Pharmaceutical Co Ltd 溶出性に優れたセフジトレンピボキシル製剤
CA2568914C (en) * 2004-06-04 2013-09-24 Affinium Pharmaceuticals, Inc. Therapeutic agents, and methods of making and using the same
WO2006024900A1 (en) * 2004-08-31 2006-03-09 Ranbaxy Laboratories Limited Highly pure cefditoren pivoxil
JP2009518399A (ja) * 2005-12-05 2009-05-07 アフィニウム ファーマシューティカルズ， インク． Ｆａｂｉ阻害剤および抗菌剤としてのヘテロ環アクリルアミド化合物
US20080069879A1 (en) * 2006-05-02 2008-03-20 Ravishekhar Bhiwgade Stable solid dosage form containing amorphous cefditoren pivoxil and process for preparation thereof
EP2687533B1 (en) 2006-07-20 2017-07-19 Debiopharm International SA Acrylamide derivatives as FAB I inhibitors
WO2008098374A1 (en) 2007-02-16 2008-08-21 Affinium Pharmaceuticals, Inc. Salts, prodrugs and polymorphs of fab i inhibitors
EP2520578A1 (en) 2011-05-06 2012-11-07 Lupin Limited Process for purification of cephalosporins
CN103421025B (zh) * 2012-05-21 2016-05-11 上海医药工业研究院 制备7α-甲氧基头孢菌素C的方法
HRP20190980T1 (hr) 2012-06-19 2019-08-23 Debiopharm International Sa Derivati predlijeka (e)-n-metil-n((3-metilbenzofuran-2 il)metil)-3-(7-okso-5,6,7,8-tetrahidro-1,8-naftiridin-3-il)akrilamida
KR101561963B1 (ko) * 2013-05-23 2015-10-22 영진약품공업 주식회사 세프디토렌 피복실의 신규 결정 형태 및 이의 제조 방법
CN103665002B (zh) * 2013-12-18 2016-02-03 成都医路康医学技术服务有限公司 一种头孢妥仑匹酯的制备方法
WO2016114727A1 (en) 2015-01-16 2016-07-21 Öğün Yusuf Toktamiş Cefditoren pivoxil compositions with improved stability and production methods thereof
EP3419628B1 (en) 2016-02-26 2020-10-14 Debiopharm International SA Medicament for treatment of diabetic foot infections
HUE062061T2 (hu) 2019-02-14 2023-09-28 Debiopharm Int Sa Afabicin készítmény, eljárás annak elõállítására
PH12021553086A1 (en) 2019-06-14 2023-08-14 Debiopharm Int Sa Medicament and use thereof for treating bacterial infections involving biofilm

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE58487B1 (en) 1984-09-07 1993-09-22 Kaisha Maiji Seika New cephalosporin compounds and the production thereof
ES2157989T3 (es) * 1993-09-29 2001-09-01 Meiji Seika Kaisha Nuevos derivados de cefalosporina.
EP0658558B1 (en) * 1993-11-17 2001-01-24 Biochemie Gesellschaft M.B.H. Separation of cephalosporin isomers
PL189548B1 (pl) * 1996-09-20 2005-08-31 Meiji Seika Kaisha Krystaliczny cefditoren piwoksylu i sposób jego wytwarzania

Also Published As

Publication number Publication date
EA199900311A1 (ru) 1999-10-28
AU714735B2 (en) 2000-01-13
RO120196B1 (ro) 2005-10-28
CA2265686A1 (en) 1998-03-26
KR100441907B1 (ko) 2004-07-27
JP2001500521A (ja) 2001-01-16
IL129016A (en) 2003-01-12
CN1116299C (zh) 2003-07-30
JP3403206B2 (ja) 2003-05-06
US6294669B1 (en) 2001-09-25
HUP9903454A3 (en) 2001-04-28
NZ334883A (en) 2000-09-29
IL129016A0 (en) 2000-02-17
HK1022912A1 (en) 2000-08-25
AU4222297A (en) 1998-04-14
CZ295199B6 (cs) 2005-06-15
EP0937083A1 (en) 1999-08-25
HU224196B1 (hu) 2005-06-28
UA55426C2 (uk) 2003-04-15
BR9712072A (pt) 1999-08-24
TR199900614T2 (xx) 1999-06-21
US6441162B2 (en) 2002-08-27
WO1998012200A1 (en) 1998-03-26
KR20000048496A (ko) 2000-07-25
PL332314A1 (en) 1999-08-30
US20020002279A1 (en) 2002-01-03
AR008483A1 (es) 2000-01-19
ID22064A (id) 1999-08-26
HUP9903454A2 (hu) 2000-03-28
EP0937083B1 (en) 2003-04-23
EA001526B1 (ru) 2001-04-23
PL189548B1 (pl) 2005-08-31
CA2265686C (en) 2006-10-31
CN1234036A (zh) 1999-11-03
DE69721290T2 (de) 2004-01-22
ATE238310T1 (de) 2003-05-15
ES2198593T3 (es) 2004-02-01
SK284973B6 (sk) 2006-03-02
SK35499A3 (en) 2000-03-13
CZ97599A3 (cs) 1999-08-11
DE69721290D1 (de) 2003-05-28

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