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PT92728A - Processo para a preparacao de derivados de piperazinilo e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de derivados de piperazinilo e de composicoes farmaceuticas que os contem

Info

Publication number
PT92728A
PT92728A PT92728A PT9272889A PT92728A PT 92728 A PT92728 A PT 92728A PT 92728 A PT92728 A PT 92728A PT 9272889 A PT9272889 A PT 9272889A PT 92728 A PT92728 A PT 92728A
Authority
PT
Portugal
Prior art keywords
pharmaceutical compositions
compositions containing
compounds
preparation
piperazinyl derivatives
Prior art date
Application number
PT92728A
Other languages
English (en)
Other versions
PT92728B (pt
Inventor
Jens Perregaard
John Willie Stenberg
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of PT92728A publication Critical patent/PT92728A/pt
Publication of PT92728B publication Critical patent/PT92728B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PT92728A 1988-12-28 1989-12-27 Processo para a preparacao de derivados de piperazinilo e de composicoes farmaceuticas que os contem PT92728B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888830312A GB8830312D0 (en) 1988-12-28 1988-12-28 Heterocyclic compounds

Publications (2)

Publication Number Publication Date
PT92728A true PT92728A (pt) 1990-06-29
PT92728B PT92728B (pt) 1995-12-29

Family

ID=10649223

Family Applications (1)

Application Number Title Priority Date Filing Date
PT92728A PT92728B (pt) 1988-12-28 1989-12-27 Processo para a preparacao de derivados de piperazinilo e de composicoes farmaceuticas que os contem

Country Status (17)

Country Link
US (1) US5002948A (pt)
EP (1) EP0376607B1 (pt)
JP (1) JP2895121B2 (pt)
AT (1) ATE102184T1 (pt)
AU (1) AU637991B2 (pt)
CA (1) CA2006356C (pt)
DE (1) DE68913487T2 (pt)
DK (1) DK169266B1 (pt)
ES (1) ES2062050T3 (pt)
FI (1) FI93005C (pt)
GB (1) GB8830312D0 (pt)
IE (1) IE62668B1 (pt)
IL (1) IL92990A (pt)
NO (1) NO174772C (pt)
NZ (1) NZ231855A (pt)
PT (1) PT92728B (pt)
ZA (1) ZA899960B (pt)

Families Citing this family (82)

* Cited by examiner, † Cited by third party
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DE3923045A1 (de) * 1989-07-13 1991-01-17 Merck Patent Gmbh Indolderivate
ATE145208T1 (de) * 1990-07-06 1996-11-15 Yoshitomi Pharmaceutical Kondensierte thiophenverbindungen und deren verwendung
US5643784A (en) * 1990-12-04 1997-07-01 H, Lundbeck A/S Indan derivatives
FR2670491B1 (fr) * 1990-12-14 1993-02-05 Adir Nouvelles piperazines 1,4-disubstituees, leur procede de preparation et les compositions pharmaceutiques les renfermant.
DE4101686A1 (de) * 1991-01-22 1992-07-23 Merck Patent Gmbh Indolderivate
NZ243065A (en) * 1991-06-13 1995-07-26 Lundbeck & Co As H Piperidine derivatives and pharmaceutical compositions
DE4127849A1 (de) * 1991-08-22 1993-02-25 Merck Patent Gmbh Benzodioxanderivate
CA2084531A1 (en) * 1991-12-19 1993-06-20 David W. Smith Antimigraine 4-pyrimidinyl and pyridinyl derivatives of indol-3yl-alkyl piperazines
DK55192D0 (da) * 1992-04-28 1992-04-28 Lundbeck & Co As H 1-piperazino-1,2-dihydroindenderivater
DK78692D0 (da) * 1992-06-12 1992-06-12 Lundbeck & Co As H Dimere piperidin- og piperazinderivater
FR2692264B1 (fr) * 1992-06-12 1994-08-05 Adir Nouvelles piperazines 1,4-disubstituees, leur procede de preparation et les compositions pharmaceutiques les contenant.
ES2050623B1 (es) * 1992-11-06 1994-12-16 Merck Patent Gmbh Derivados de 1,4-benzodioxano.
DK148392D0 (da) * 1992-12-09 1992-12-09 Lundbeck & Co As H Heterocykliske forbindelser
CA2152160A1 (en) * 1992-12-21 1994-07-07 Tomoyuki Ikemoto N-substituted indole derivative
GB9305623D0 (en) * 1993-03-18 1993-05-05 Merck Sharp & Dohme Therapeutic agents
RU2118322C1 (ru) * 1993-07-05 1998-08-27 Дюфар Интернэшнл Рисерч Б.В. 2,3-дигидро-1,4-бензодиокси-5-ил-пиперазиновые производные или их соли
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AR013206A1 (es) * 1997-07-25 2000-12-13 Lundbeck & Co As H Derivados indol y 2,3-dihidroindol, composiciones farmaceuticas que contienen estos compuestos y el uso de dichos compuestos para la preparacion de un medicamento para el tratamiento de desordenes sensibles a la inhibicion de la reabsorcion de serotonina y antagonismo de receptores 5-ht1a.
WO1999051576A1 (en) * 1998-04-08 1999-10-14 American Home Products Corporation N-aryloxyethylamine derivatives for the treatment of depression
AR022303A1 (es) 1999-01-22 2002-09-04 Lundbeck & Co As H Derivados de piperidina, tetrahidropiridina y piperazina, su preparacion y utilizacion
US7067513B1 (en) * 1999-08-23 2006-06-27 Solvay Pharmaceuticals B.V. Phenylpiperazines
PT1246816E (pt) * 1999-12-30 2004-08-31 Lundbeck & Co As H Derivados de fenilpiperazina substituidos sua preparacao e utilizacao
CA2395867A1 (en) * 1999-12-30 2001-07-12 Kim Andersen Phenylpiperazinyl derivatives
AR027134A1 (es) * 1999-12-30 2003-03-12 Lundbeck & Co As H Derivados de indol.
US7211594B2 (en) * 2000-07-31 2007-05-01 Signal Pharmaceuticals, Llc Indazole compounds and compositions thereof as JNK inhibitors and for the treatment of diseases associated therewith
US6897231B2 (en) * 2000-07-31 2005-05-24 Signal Pharmaceuticals, Inc. Indazole derivatives as JNK inhibitors and compositions and methods related thereto
AR035521A1 (es) * 2000-12-22 2004-06-02 Lundbeck & Co As H Derivados de 3-indolina y composicion farmaceutica que los comprende
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US6559169B2 (en) 2001-04-24 2003-05-06 Wyeth Antidepressant azaheterocyclymethyl derivatives of 2,3-dihydro-1,4-benzodioxan
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BRPI0716436B8 (pt) 2006-08-25 2021-05-25 Boehringer Ingelheim Int sistema de liberação controlada e método para fabricação do mesmo
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WO2011014128A1 (en) * 2009-07-30 2011-02-03 National University Of Singapore Small molecule inhibitors of isoprenylcysteine carboxyl methyltransferase with potential anticancer activity
US8912220B2 (en) * 2009-08-10 2014-12-16 Galenea Pharmaceuticals Compounds and methods of use thereof
CN102993186B (zh) * 2012-12-20 2015-11-18 北京海步国际医药科技发展有限公司 一种新型的哌嗪衍生物
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CN106065018B (zh) * 2015-04-23 2020-04-21 广东东阳光药业有限公司 取代的吲哚化合物及其使用方法和用途
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Also Published As

Publication number Publication date
EP0376607A1 (en) 1990-07-04
AU637991B2 (en) 1993-06-17
NO895281D0 (no) 1989-12-27
FI896300A0 (fi) 1989-12-28
US5002948A (en) 1991-03-26
IL92990A0 (en) 1990-09-17
IE893976L (en) 1990-06-13
DK645689A (da) 1990-06-29
NZ231855A (en) 1992-02-25
EP0376607B1 (en) 1994-03-02
IE62668B1 (en) 1995-02-22
ATE102184T1 (de) 1994-03-15
AU4719889A (en) 1990-07-05
DK645689D0 (da) 1989-12-19
NO895281L (no) 1990-06-29
DE68913487D1 (de) 1994-04-07
DK169266B1 (da) 1994-09-26
FI93005B (fi) 1994-10-31
FI93005C (fi) 1995-02-10
DE68913487T2 (de) 1994-08-04
PT92728B (pt) 1995-12-29
ES2062050T3 (es) 1994-12-16
JPH02225460A (ja) 1990-09-07
ZA899960B (en) 1990-11-28
JP2895121B2 (ja) 1999-05-24
CA2006356A1 (en) 1990-06-28
GB8830312D0 (en) 1989-02-22
CA2006356C (en) 1999-09-14
NO174772B (no) 1994-03-28
IL92990A (en) 1995-01-24
NO174772C (no) 1994-07-06

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