PT2001862E - Sais de malato e polimorfos do ácido (3s,5s)-7-[3- amino-5-metil-piperidinil]-1-ciclopropil-1,4-dihidro- 8-metoxi-4-oxo-3-quinolinocarboxílico - Google Patents

Sais de malato e polimorfos do ácido (3s,5s)-7-[3- amino-5-metil-piperidinil]-1-ciclopropil-1,4-dihidro- 8-metoxi-4-oxo-3-quinolinocarboxílico Download PDF

Info

Publication number: PT2001862E
Authority: PT; Portugal
Prior art keywords: polymorphs; piperidinyl; cyclopropyl; dihydro; oxo
Prior art date: 2006-03-28

Application number

PT07735261T

Other languages

English (en)

Inventor

Nancy Lee Redman-Furey

Jane Ellen Godlewski

Michael Lloyd Dicks

Original Assignee

Warner Chilcott Co Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-03-28

Filing date

2007-03-26

Publication date

2011-07-20

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38441484&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2001862(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2007-03-26 Application filed by Warner Chilcott Co Llc filed Critical Warner Chilcott Co Llc

2011-07-20 Publication of PT2001862E publication Critical patent/PT2001862E/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

PT07735261T 2006-03-28 2007-03-26 Sais de malato e polimorfos do ácido (3s,5s)-7-[3- amino-5-metil-piperidinil]-1-ciclopropil-1,4-dihidro- 8-metoxi-4-oxo-3-quinolinocarboxílico PT2001862E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US78648306P	2006-03-28	2006-03-28

Publications (1)

Publication Number	Publication Date
PT2001862E true PT2001862E (pt)	2011-07-20

Family

ID=38441484

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT07735261T PT2001862E (pt)	2006-03-28	2007-03-26	Sais de malato e polimorfos do ácido (3s,5s)-7-[3- amino-5-metil-piperidinil]-1-ciclopropil-1,4-dihidro- 8-metoxi-4-oxo-3-quinolinocarboxílico

Country Status (27)

Country	Link
US (1)	US8039485B2 (pt)
EP (1)	EP2001862B1 (pt)
JP (1)	JP5097967B2 (pt)
KR (1)	KR101102288B1 (pt)
AR (2)	AR060189A1 (pt)
AT (1)	ATE507219T1 (pt)
AU (1)	AU2007230630B2 (pt)
BR (1)	BRPI0709772B8 (pt)
CA (1)	CA2647346C (pt)
CY (1)	CY1111683T1 (pt)
DE (1)	DE602007014191D1 (pt)
DK (1)	DK2001862T3 (pt)
ES (1)	ES2366150T3 (pt)
HR (1)	HRP20110558T1 (pt)
IL (1)	IL193990A (pt)
MA (1)	MA30554B1 (pt)
MX (1)	MX2008012328A (pt)
MY (1)	MY148393A (pt)
NZ (1)	NZ570494A (pt)
PE (1)	PE20080175A1 (pt)
PL (1)	PL2001862T3 (pt)
PT (1)	PT2001862E (pt)
SI (1)	SI2001862T1 (pt)
SM (1)	SMP200800058B (pt)
TW (1)	TWI364419B (pt)
WO (1)	WO2007110834A2 (pt)
ZA (1)	ZA200807158B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1999125A2 (en) *	2006-03-28	2008-12-10	The Procter and Gamble Company	A coupling process for preparing quinolone intermediates
US8658183B2 (en) *	2007-08-09	2014-02-25	Taigen Biotechnology Company, Ltd.	Antimicrobial parenteral formulation
NZ588898A (en) *	2008-07-01	2012-09-28	Taigen Biotechnology Co Ltd	Use of nemonoxacin for treating antibiotic-resistant staphylococcus aureus infection
CN101618039B (zh) *	2008-07-02	2012-04-11	太景生物科技股份有限公司	肺炎的治疗药物
US8553466B2 (en)	2010-03-04	2013-10-08	Samsung Electronics Co., Ltd.	Non-volatile memory device, erasing method thereof, and memory system including the same
CZ304984B6 (cs)	2012-10-12	2015-03-11	Zentiva, K.S.	Zlepšený způsob výroby a nové intermediáty syntézy elvitegraviru
CZ304983B6 (cs) *	2012-10-12	2015-03-11	Zentiva, K.S.	Způsob výroby a nové intermediáty syntézy elvitegraviru
CN103145615B (zh) *	2013-03-20	2015-07-29	浙江医药股份有限公司	一种奈诺沙星螯合物的后处理方法
CN114437026A (zh) *	2021-10-26	2022-05-06	浙江医药股份有限公司新昌制药厂	一种低组合物杂质的苹果酸奈诺沙星原料药及其制备方法
CN116332831B (zh) *	2023-03-15	2025-10-28	浙江医药股份有限公司新昌制药厂	氨基被Boc保护的3-氨基-5-甲基哌啶的提纯方法

Family Cites Families (88)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4017622A (en)	1972-12-18	1977-04-12	Dainippon Pharmaceutical Co., Ltd.	Piperazine derivatives
JPS5186476A (en)	1975-01-17	1976-07-29	Yoshitomi Pharmaceutical	Shinkina kinoronkarubonsanjudotaino seiho
JPS5845426B2 (ja)	1978-09-29	1983-10-08	杏林製薬株式会社	置換キノリンカルボン酸誘導体
JPS604820B2 (ja)	1979-02-26	1985-02-06	大塚製薬株式会社	キノリンカルボン酸誘導体
JPS5649382A (en)	1979-09-28	1981-05-02	Dainippon Pharmaceut Co Ltd	6-fluoro-7-cyclic amino-1,8-naphthylidine derivative and its salt
US4665079A (en)	1984-02-17	1987-05-12	Warner-Lambert Company	Antibacterial agents
US5281612A (en)	1982-09-09	1994-01-25	Warner-Lambert Company	Naphthyridine antibacterial agents
IE55898B1 (en)	1982-09-09	1991-02-14	Warner Lambert Co	Antibacterial agents
DE3248506A1 (de)	1982-12-29	1984-07-05	Bayer Ag, 5090 Leverkusen	1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7(alkyl-1-piperazinyl)-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
US4994599A (en)	1987-11-20	1991-02-19	Abbott Laboratories	Intermediates for producing quinolone-3-carboxylic acids
JPS60221484A (ja)	1984-04-17	1985-11-06	Fuji Photo Film Co Ltd	放射線像変換方法およびその方法に用いられる放射線像変換パネル
DE3420798A1 (de)	1984-06-04	1985-12-05	Bayer Ag, 5090 Leverkusen	7-(3-aryl-l-piperazinyl)- sowie 7-(3-cyclohexyl-l-piperazinyl)-3-chinoloncarbonsaeuren
US4822801A (en)	1984-07-20	1989-04-18	Warner-Lambert Company	4-oxo-1,4-dihydroquinoline-3-carboxylic acid derivative as antibacterial agents
US4771054A (en)	1985-01-23	1988-09-13	Warner-Lambert Company	Antibacterial agents
AU5427286A (en)	1985-03-08	1986-09-11	Kyorin Pharmaceutical Co. Ltd.	7-(1-pyrrolidinyl)-3-quinolinecarboxylic acid derivatives
JPS61205258A (ja)	1985-03-08	1986-09-11	Kyorin Pharmaceut Co Ltd	キノロンカルボン酸誘導体及びその製造方法
JPS61225181A (ja)	1986-02-04	1986-10-06	Kyorin Pharmaceut Co Ltd	キノロンカルボン酸誘導体及びその製造方法
IL79189A (en)	1985-06-26	1990-07-12	Daiichi Seiyaku Co	Quinoline and/or naphthyridine-4-oxo-3-carboxylic acid derivatives,process for their preparation and pharmaceutical compositions comprising them
JPS6236377A (ja)	1985-07-03	1987-02-17	Kyorin Pharmaceut Co Ltd	キノロンカルボン酸誘導体
JPH089597B2 (ja)	1986-01-21	1996-01-31	杏林製薬株式会社	選択毒性に優れた８‐アルコキシキノロンカルボン酸およびその塩並びにその製造方法
DE3705621C2 (de)	1986-02-25	1997-01-09	Otsuka Pharma Co Ltd	Heterocyclisch substituierte Chinoloncarbonsäurederivate
JPS62205060A (ja)	1986-03-04	1987-09-09	Kyorin Pharmaceut Co Ltd	８位置換キノロンカルボン酸誘導体
JPS62215572A (ja)	1986-03-17	1987-09-22	Kyorin Pharmaceut Co Ltd	キノロンカルボン酸誘導体
JPH0717608B2 (ja)	1986-04-25	1995-03-01	杏林製薬株式会社	６−アルコキシキノロンカルボン酸誘導体
DE3704907A1 (de)	1987-02-17	1988-08-25	Bayer Ag	Topisch anwendbare zubereitungen von gyrase-inhibitoren in kombination mit kortikosteroiden
US4780468A (en)	1987-08-07	1988-10-25	Warner-Lambert Company	8-trifluoromethyl quinolones as antibacterial agents
US4997946A (en)	1987-08-18	1991-03-05	Eastman Kodak Company	Process for the iodination of hydroxyaromatic and aminoaromatic compounds
JPH0676400B2 (ja)	1987-08-25	1994-09-28	大日本製薬株式会社	新規ピリドンカルボン酸誘導体、そのエステルおよびその塩
US4921857A (en)	1987-09-18	1990-05-01	Merck & Co., Inc.	4-Oxo-4h-quinolizine-3-carboxylic acids and derivatives thereof
US4920120A (en)	1988-01-25	1990-04-24	Warner-Lambert Company	Antibacterial agents
JPH0395177A (ja)	1988-05-19	1991-04-19	Chugai Pharmaceut Co Ltd	新規キノロンカルボン酸誘導体
JP2844079B2 (ja)	1988-05-23	1999-01-06	塩野義製薬株式会社	ピリドンカルボン酸系抗菌剤
DE3906365A1 (de)	1988-07-15	1990-01-18	Bayer Ag	7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
FI95130C (fi)	1988-07-20	1995-12-27	Sankyo Co	Menetelmä lääkeaineena käyttökelpoisten 4-oksokinoliini-3-karboksyylihapon johdannaisten valmistamiseksi
US5286723A (en)	1988-08-31	1994-02-15	Daiichi Seiyaku Co., Ltd.	Spiro compound
US5328908A (en)	1988-10-24	1994-07-12	Procter & Gamble Pharmaceuticals, Inc.	Antimicrobial quinolone thioureas
EP0366189A3 (en)	1988-10-24	1992-01-02	Norwich Eaton Pharmaceuticals, Inc.	Novel antimicrobial lactam-quinolones
CA2001203C (en)	1988-10-24	2001-02-13	Thomas P. Demuth, Jr.	Novel antimicrobial dithiocarbamoyl quinolones
US5164402A (en)	1989-08-16	1992-11-17	Pfizer Inc	Azabicyclo quinolone and naphthyridinone carboxylic acids
IE66202B1 (en)	1989-08-16	1995-12-13	Pfizer	Azabicyclo quinolone carboxylic acids
CN1054980A (zh)	1990-02-19	1991-10-02	杏林制药株式会社	具有旋光活性的8-甲氧基喹诺酮羧酸衍生物，它们的制备方法以及它们的中间体
US5116834A (en)	1990-04-12	1992-05-26	Warner-Lambert Company	Quinolinecarboxylic acid antibacterial agents
US5726182A (en)	1990-05-02	1998-03-10	Abbott Laboratories	Quinolizinone type compounds
US5580872A (en)	1990-05-02	1996-12-03	Abbott Laboratories	Quinolizinone type compounds
WO1991016894A1 (en)	1990-05-02	1991-11-14	Abbott Laboratories	Quinolizinone type compounds
JPH0778065B2 (ja)	1990-07-06	1995-08-23	杏林製薬株式会社	（６，７―置換―８―アルコキシ―１―シクロプロピル―１，４―ジヒドロ―４―オキソ―３―キノリンカルボン酸―ｏ▲上３▼，ｏ▲上４▼）ビス（アシルオキシ―ｏ）ホウ素化合物及びその塩並びにその製造方法
US5072001A (en)	1990-11-30	1991-12-10	Warner-Lambert Company	Certain optically active substituted 3-pyrraidine acetic acid derivatives useful as intermediates
US5364861A (en)	1990-11-30	1994-11-15	Warner-Lambert Company	Optical isomers of 7-[3-(1,1-dialkylmethyl-1-amino-1-pyrrolidinyl]-quinolones and naphthyridones as antibacterial agents
US5258528A (en)	1990-11-30	1993-11-02	Warner-Lambert Company	Individual stereoisomers of pyrrolidine methanamines substituted on the ring nitrogen by a 1-phenylethyl group
DE4120646A1 (de)	1991-06-22	1992-12-24	Bayer Ag	7-isoindolinyl-chinolon- und naphthyridoncarbonsaeure-derivate
DE4123918A1 (de)	1991-07-19	1993-01-21	Bayer Ag	8-vinyl- und 8-ethinyl-chinoloncarbonsaeuren
US5412098A (en)	1991-12-27	1995-05-02	Wakunaga Seiyaku Kabushiki Kaisha	Quinolone derivative or salt thereof and antibacterial containing the same
EP0550016A1 (en)	1991-12-31	1993-07-07	Korea Research Institute Of Chemical Technology	Novel quinolone carboxylic acid derivatives and processes for preparing same
NO304832B1 (no)	1992-05-27	1999-02-22	Ube Industries	Aminokinolonderivater samt middel mot HIV
DE4230804A1 (de)	1992-09-15	1994-03-17	Bayer Ag	7-Isoindolinyl-chinolon- und -naphthyridon-Derivate
DE4234078A1 (de)	1992-10-09	1994-04-14	Bayer Ag	Chinoloncarbonsäuren
KR0148277B1 (ko)	1993-01-18	1998-11-02	채영복	신규한 플루오르퀴놀론계 유도체 및 그의 제조방법
DE4301246A1 (de)	1993-01-19	1994-07-21	Bayer Ag	Chinolon- und Naphthyridoncarbonsäurederivate
DE4301245A1 (de)	1993-01-19	1994-07-21	Bayer Ag	Fluor-trifluormethylbenzoesäure-Derivate
CA2152828A1 (en)	1993-03-16	1994-07-07	Shin-Ichi Uesato	8-methoxy-quinolonecarboxylic acid derivatives
TW252107B (pt)	1993-08-27	1995-07-21	Hokuriku Pharmacetical Co Ltd
JPH09503783A (ja)	1993-10-14	1997-04-15	アボツト・ラボラトリーズ	キノリジノン型化合物
WO1996005192A1 (en)	1994-08-12	1996-02-22	Toyama Chemical Co., Ltd.	Novel quinolone- or naphthyridonecarboxylic acid derivative or salt thereof
CA2212226A1 (en)	1995-02-02	1995-08-10	Katsumi Chiba	Bicyclic amino group-substituted pyridonecarboxylic acid derivatives, esters thereof and salts thereof, and bicyclic amines useful as intermediates thereof
JP3745433B2 (ja)	1995-02-02	2006-02-15	第一製薬株式会社	複素環式化合物
DK0807630T3 (da)	1995-02-02	2003-09-01	Daiichi Seiyaku Co	Heterocykliske forbindelser
DE19512484A1 (de)	1995-04-04	1996-10-17	Bayer Ag	Kohlenhydratmodifizierte Cytostatika
JPH11510478A (ja)	1995-06-06	1999-09-14	アボツト・ラボラトリーズ	キノリジノン型化合物
IT1279532B1 (it)	1995-07-24	1997-12-16	Mediolanum Farmaceutici Spa	Derivati chinolonici non fluorurati e loro impiego come agenti antibatterici
PT911328E (pt)	1995-11-22	2006-05-31	Daiichi Seiyaku Co	Derivados susbstituidos de aminocicloalquilpirrolidina
KR100531967B1 (ko)	1996-10-25	2005-11-30	다이이찌 세이야꾸 가부시기가이샤	트리사이클릭 아민 유도체, 이를 포함하는 항균제 및 퀴놀론 화합물의 제조방법
US6274592B1 (en)	1997-02-04	2001-08-14	Senju Pharmaceutical Co., Ltd.	Method for stabilizing arylcarboxylic acid, stabilizer thereof and aqueous solution containing stabilized arylcarboxylic acid
KR20010012740A (ko)	1997-05-21	2001-02-26	스즈키 다다시	시스-이치환된 아미노사이클로알킬 피롤리딘 유도체
MY119816A (en)	1997-05-30	2005-07-29	Daiichi Seiyaku Co	Substituted cyclobutylamine derivatives
KR100241673B1 (ko)	1997-08-09	2000-03-02	김충섭	퀴놀리진 카르복실산 유도체
AU735186B2 (en) *	1997-09-15	2001-07-05	Warner Chilcott Company, Llc	Antimicrobial quinolones, their compositions and uses
US6387928B1 (en)	1997-09-15	2002-05-14	The Procter & Gamble Co.	Antimicrobial quinolones, their compositions and uses
GB9822440D0 (en)	1998-10-14	1998-12-09	Smithkline Beecham Plc	Medicaments
GB9914486D0 (en)	1999-06-21	1999-08-18	Smithkline Beecham Plc	Medicaments
MXPA02005989A (es)	2000-01-24	2002-10-23	Warner Lambert Co	Agentes antibacteriales de 3-aminoquinazolin-2,4-diona.
ES2249489T3 (es)	2000-12-14	2006-04-01	THE PROCTER & GAMBLE COMPANY	Quinolonas antimicrobianas.
JP4250353B2 (ja)	2001-06-22	2009-04-08	エドワーズ株式会社	真空ポンプ
US6900224B2 (en)	2002-07-31	2005-05-31	The Procter & Gamble Company	Antimicrobial quinolones, their compositions and uses
US6803469B2 (en)	2002-08-05	2004-10-12	The Procter & Gamble Company	Process for preparing quinolone antibiotic intermediates
SI1675852T1 (sl) *	2003-09-22	2009-06-30	Janssen Pharmaceutica Nv	7-amino alkilidenil-heterociklični kinoloni in naftiridoni
US7732612B2 (en)	2004-09-09	2010-06-08	Janssen Pharmaceutica, N.V.	7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
EP1999106B1 (en) *	2006-03-28	2012-06-27	TaiGen Biotechnology Co., Ltd.	A hydride reduction process for preparing quinolone intermediates
EP1999125A2 (en)	2006-03-28	2008-12-10	The Procter and Gamble Company	A coupling process for preparing quinolone intermediates

2007
- 2007-03-26 AU AU2007230630A patent/AU2007230630B2/en active Active
- 2007-03-26 AT AT07735261T patent/ATE507219T1/de active
- 2007-03-26 US US11/728,343 patent/US8039485B2/en active Active
- 2007-03-26 PL PL07735261T patent/PL2001862T3/pl unknown
- 2007-03-26 MY MYPI20083531A patent/MY148393A/en unknown
- 2007-03-26 BR BRPI0709772A patent/BRPI0709772B8/pt not_active IP Right Cessation
- 2007-03-26 ES ES07735261T patent/ES2366150T3/es active Active
- 2007-03-26 PT PT07735261T patent/PT2001862E/pt unknown
- 2007-03-26 CA CA2647346A patent/CA2647346C/en active Active
- 2007-03-26 DE DE602007014191T patent/DE602007014191D1/de active Active
- 2007-03-26 SI SI200730599T patent/SI2001862T1/sl unknown
- 2007-03-26 DK DK07735261.5T patent/DK2001862T3/da active
- 2007-03-26 WO PCT/IB2007/051055 patent/WO2007110834A2/en not_active Ceased
- 2007-03-26 JP JP2009502298A patent/JP5097967B2/ja active Active
- 2007-03-26 MX MX2008012328A patent/MX2008012328A/es active IP Right Grant
- 2007-03-26 SM SM200800058T patent/SMP200800058B/it unknown
- 2007-03-26 NZ NZ570494A patent/NZ570494A/en unknown
- 2007-03-26 HR HR20110558T patent/HRP20110558T1/hr unknown
- 2007-03-26 KR KR1020087023397A patent/KR101102288B1/ko active Active
- 2007-03-26 EP EP07735261A patent/EP2001862B1/en active Active
- 2007-03-27 TW TW096110617A patent/TWI364419B/zh active
- 2007-03-28 AR ARP070101308A patent/AR060189A1/es not_active Application Discontinuation
- 2007-03-28 PE PE2007000348A patent/PE20080175A1/es active IP Right Grant
- 2007-04-09 AR ARP070101472A patent/AR060377A1/es not_active Application Discontinuation
2008
- 2008-08-19 ZA ZA200807158A patent/ZA200807158B/xx unknown
- 2008-09-09 IL IL193990A patent/IL193990A/en active IP Right Grant
- 2008-10-15 MA MA31295A patent/MA30554B1/fr unknown
2011
- 2011-07-11 CY CY20111100668T patent/CY1111683T1/el unknown

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Publication number	Publication date
DK2001862T3 (da)	2011-08-08
TWI364419B (en)	2012-05-21
PL2001862T3 (pl)	2011-09-30
DE602007014191D1 (en)	2011-06-09
PE20080175A1 (es)	2008-03-14
BRPI0709772B1 (pt)	2019-10-15
US8039485B2 (en)	2011-10-18
IL193990A (en)	2014-12-31
AR060377A1 (es)	2008-06-11
TW200808759A (en)	2008-02-16
CA2647346A1 (en)	2007-10-04
EP2001862B1 (en)	2011-04-27
SMAP200800058A (it)	2008-10-29
AR060189A1 (es)	2008-05-28
SI2001862T1 (sl)	2011-10-28
MX2008012328A (es)	2008-10-09
KR101102288B1 (ko)	2012-01-03
HRP20110558T1 (hr)	2011-09-30
ATE507219T1 (de)	2011-05-15
US20070232650A1 (en)	2007-10-04
BRPI0709772B8 (pt)	2021-05-25
JP5097967B2 (ja)	2012-12-12
BRPI0709772A2 (pt)	2011-07-26
RU2417222C2 (ru)	2011-04-27
SMP200800058B (it)	2009-09-07
AU2007230630B2 (en)	2012-12-20
MY148393A (en)	2013-04-15
ZA200807158B (en)	2009-09-30
KR20090004887A (ko)	2009-01-12
NZ570494A (en)	2011-09-30
RU2008134544A (ru)	2010-05-10
WO2007110834A3 (en)	2007-12-06
MA30554B1 (fr)	2009-07-01
AU2007230630A1 (en)	2007-10-04
JP2009531417A (ja)	2009-09-03
EP2001862A2 (en)	2008-12-17
CY1111683T1 (el)	2015-10-07
WO2007110834A2 (en)	2007-10-04
ES2366150T3 (es)	2011-10-17
CA2647346C (en)	2011-07-19

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