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PE20140640A1 - Composicion de complejo oral que contiene ester de acido graso omega-3 e inhibidor de reductasa hmg-coa - Google Patents

Composicion de complejo oral que contiene ester de acido graso omega-3 e inhibidor de reductasa hmg-coa

Info

Publication number
PE20140640A1
PE20140640A1 PE2013002066A PE2013002066A PE20140640A1 PE 20140640 A1 PE20140640 A1 PE 20140640A1 PE 2013002066 A PE2013002066 A PE 2013002066A PE 2013002066 A PE2013002066 A PE 2013002066A PE 20140640 A1 PE20140640 A1 PE 20140640A1
Authority
PE
Peru
Prior art keywords
composition
fatty acid
capsule
coa
coating
Prior art date
Application number
PE2013002066A
Other languages
English (en)
Inventor
Yong Ii Kim
Eun Jin Yoon
Ho Taek Im
Yoon Sub Shin
Jae Hyun Park
Jong Soo Woo
Original Assignee
Hanmi Pharm Ind Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47280992&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20140640(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hanmi Pharm Ind Co Ltd filed Critical Hanmi Pharm Ind Co Ltd
Publication of PE20140640A1 publication Critical patent/PE20140640A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

REFERIDA A UNA COMPOSICION DE COMPLEJO ORAL QUE COMPRENDE: a) UN NUCLEO DE CAPSULA BLANDA QUE CONTIENE ESTERES DE ACIDO GRASO OMEGA 3 TALES COMO ESTERES ETILICOS DE ACIDO EICOSAPENTAENOICO Y ACIDO DOCOSANHEXAENOICO, b) UNA PRIMERA CAPA DE RECUBRIMIENTO QUE ENVUELVE AL NUCLEO DE CAPSULA BLANDA Y COMPRENDE UN MATERIAL DE RECUBRIMIENTO HIDROFOBICO TAL COMO ACETATO DE CELULOSA, ACETATO POLIVINILICO, ETIL CELULOSA, COPOLIMEROS DE ACIDO (MET)ACRILICO Y UNA MEZCLA DE LOS MISMOS, c) UNA SEGUNDA CAPA DE RECUBRIMIENTO DEPOSITADA SOBRE LA PRIMERA CAPA DE RECUBRIMIENTO Y LA CUAL CONTIENE ROSUVASTATINA O UNA SAL FARMACEUTICAMENTE ACEPTABLE DE LA MISMA Y ALCOHOL POLIVINILICO, COPOLIMERO DE INJERTO ALCOHOL POLIVINILICO-POLIETILENO GLICOL O UNA MEZCLA DE LOS MISMOS. TAMBIEN ESTA REFERIDA A UN METODO DE PREPARACION. DICHA COMPOSICION ES UTIL EN EL TRATAMIENTO DE HIPERLIPIDEMIA
PE2013002066A 2011-03-23 2012-03-23 Composicion de complejo oral que contiene ester de acido graso omega-3 e inhibidor de reductasa hmg-coa PE20140640A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20110025940 2011-03-23
KR1020110041168A KR101310710B1 (ko) 2011-03-23 2011-04-29 오메가-3 지방산 에스테르 및 ＨＭＧ-ＣｏＡ 환원효소 억제제를 포함하는 경구용 복합 조성물

Publications (1)

Publication Number Publication Date
PE20140640A1 true PE20140640A1 (es) 2014-06-11

Family

ID=47280992

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2013002066A PE20140640A1 (es) 2011-03-23 2012-03-23 Composicion de complejo oral que contiene ester de acido graso omega-3 e inhibidor de reductasa hmg-coa

Country Status (31)

Country Link
US (1) US20140010872A1 (es)
EP (1) EP2688558B1 (es)
JP (1) JP2014508802A (es)
KR (1) KR101310710B1 (es)
CN (1) CN103442699B (es)
AR (1) AR085547A1 (es)
AU (1) AU2012231944B2 (es)
BR (1) BR112013023819A2 (es)
CA (1) CA2830342C (es)
CL (1) CL2013002611A1 (es)
CO (1) CO6801750A2 (es)
CR (1) CR20130491A (es)
DO (1) DOP2013000210A (es)
EA (1) EA023405B1 (es)
EC (1) ECSP13012959A (es)
ES (1) ES2550392T3 (es)
GT (1) GT201300217A (es)
IL (1) IL228516A (es)
JO (1) JO3071B1 (es)
MA (1) MA35042B1 (es)
MX (1) MX343097B (es)
MY (1) MY157200A (es)
NI (1) NI201300086A (es)
PE (1) PE20140640A1 (es)
PH (1) PH12013501946A1 (es)
SA (1) SA112330374B1 (es)
SG (1) SG193491A1 (es)
TW (1) TWI571271B (es)
UA (1) UA106457C2 (es)
WO (1) WO2012128587A2 (es)
ZA (1) ZA201307871B (es)

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Also Published As

Publication number Publication date
EA023405B1 (ru) 2016-05-31
NI201300086A (es) 2014-05-05
EA201391372A1 (ru) 2014-01-30
JO3071B1 (ar) 2017-03-15
EP2688558B1 (en) 2015-10-14
WO2012128587A3 (en) 2012-11-15
EP2688558A2 (en) 2014-01-29
SA112330374B1 (ar) 2015-01-08
MY157200A (en) 2016-05-13
ECSP13012959A (es) 2013-11-29
HK1189173A1 (en) 2014-05-30
NZ616907A (en) 2016-02-26
IL228516A0 (en) 2013-12-31
TW201249483A (en) 2012-12-16
CN103442699B (zh) 2015-07-01
DOP2013000210A (es) 2014-01-31
ZA201307871B (en) 2015-01-28
UA106457C2 (ru) 2014-08-26
CN103442699A (zh) 2013-12-11
SG193491A1 (en) 2013-10-30
JP2014508802A (ja) 2014-04-10
CR20130491A (es) 2013-10-22
GT201300217A (es) 2014-12-30
CA2830342C (en) 2016-01-19
BR112013023819A2 (pt) 2016-12-13
PH12013501946A1 (en) 2014-01-06
MX343097B (es) 2016-10-25
AR085547A1 (es) 2013-10-09
CO6801750A2 (es) 2013-11-29
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