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MX2009009838A - Esteres de acidos grasos de glucocorticoides como agentes antiinflamatorios y anti-cancer. - Google Patents

Esteres de acidos grasos de glucocorticoides como agentes antiinflamatorios y anti-cancer.

Info

Publication number
MX2009009838A
MX2009009838A MX2009009838A MX2009009838A MX2009009838A MX 2009009838 A MX2009009838 A MX 2009009838A MX 2009009838 A MX2009009838 A MX 2009009838A MX 2009009838 A MX2009009838 A MX 2009009838A MX 2009009838 A MX2009009838 A MX 2009009838A
Authority
MX
Mexico
Prior art keywords
glucocorticoids
inflammatory
fatty acid
acid esters
cancer agents
Prior art date
Application number
MX2009009838A
Other languages
English (en)
Inventor
Finn Myhren
Marit Liland Sandvold
Ole Henrik Eriksen
Steinar Hagen
Original Assignee
Clavis Pharma Asa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clavis Pharma Asa filed Critical Clavis Pharma Asa
Publication of MX2009009838A publication Critical patent/MX2009009838A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se refiere a ciertos derivados de ácidos grasos insaturados de los ésteres de ácidos grasos de los glucocorticoides activos terapéuticamente, como agentes antiinflamatorios y anti-cáncer y a las formulaciones farmacéuticas que los contienen.
MX2009009838A 2007-03-20 2008-03-13 Esteres de acidos grasos de glucocorticoides como agentes antiinflamatorios y anti-cancer. MX2009009838A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO20071485A NO331891B1 (no) 2007-03-20 2007-03-20 Kjemiske forbindelser, et farmasoytisk preparat inneholdende slike forbindelser, samt anvendelse derav for behandling av kreft, inflammasjon og KOLS
PCT/NO2008/000096 WO2008115069A2 (en) 2007-03-20 2008-03-13 Fatty acid esters of glucocorticoids as anti-inflammatory and anti-cancer agents

Publications (1)

Publication Number Publication Date
MX2009009838A true MX2009009838A (es) 2010-01-15

Family

ID=39734182

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009009838A MX2009009838A (es) 2007-03-20 2008-03-13 Esteres de acidos grasos de glucocorticoides como agentes antiinflamatorios y anti-cancer.

Country Status (16)

Country Link
US (1) US9428540B2 (es)
EP (1) EP2121723A2 (es)
JP (2) JP2010522233A (es)
KR (1) KR20090123961A (es)
CN (1) CN101687904A (es)
AU (1) AU2008227246B2 (es)
CA (1) CA2680155A1 (es)
IL (1) IL200655A0 (es)
MX (1) MX2009009838A (es)
NO (1) NO331891B1 (es)
NZ (1) NZ579382A (es)
RU (1) RU2462472C2 (es)
TW (1) TWI428133B (es)
UA (1) UA96794C2 (es)
WO (1) WO2008115069A2 (es)
ZA (1) ZA200906226B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8497292B2 (en) 2005-12-28 2013-07-30 Translational Therapeutics, Inc. Translational dysfunction based therapeutics
NO331891B1 (no) 2007-03-20 2012-04-30 Clavis Pharma Asa Kjemiske forbindelser, et farmasoytisk preparat inneholdende slike forbindelser, samt anvendelse derav for behandling av kreft, inflammasjon og KOLS
GB201006181D0 (en) 2010-04-14 2010-06-02 Ayanda As Composition
PT105723B (pt) * 2011-05-26 2014-03-24 Hovione Farmaci Ncia S A Método para a preparação de compostos orgânicos biologicamente activos
US9155747B2 (en) * 2012-09-13 2015-10-13 Chiesi Farmaceutici S.P.A. Isoxazolidine derivatives
SG10202001787QA (en) 2016-06-02 2020-04-29 Abbvie Inc Glucocorticoid receptor agonist and immunoconjugates thereof
TW201834698A (zh) * 2017-03-03 2018-10-01 國立研究開發法人國立癌症研究中心 抗ｉｌ－７ｒ抗體之抗體藥物共軛物與處置癌或發炎用之包含抗ｉｌ－７ｒ抗體與細胞傷害劑之抗體藥物共軛物之醫藥組成物
CN108659090A (zh) * 2017-03-31 2018-10-16 天津药业研究院有限公司 一种17β-硫代羧酸氯甲酯类甾体化合物的制备方法
PE20201286A1 (es) 2017-12-01 2020-11-24 Abbvie Inc Agonista del receptor de glucocorticoides e inmunoconjugados de este

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1227992A (es) * 1968-01-23 1971-04-15 Koninklijke Gist Spiritus
IT1043956B (it) * 1970-10-17 1980-02-29 Isf Spa 21 esteri di acidi grassi insaturi del desa e beta metazone
JPS56138200A (en) * 1980-02-15 1981-10-28 Glaxo Group Ltd Androstane carbothioate compound
SE8403905D0 (sv) * 1984-07-30 1984-07-30 Draco Ab Liposomes and steroid esters
JPH0381286A (ja) * 1989-08-22 1991-04-05 Green Cross Corp:The ステロイド外用剤
JPH05132498A (ja) * 1991-11-08 1993-05-28 Asahi Glass Co Ltd ステロイド誘導体およびその製剤
GB2321455A (en) * 1997-01-24 1998-07-29 Norsk Hydro As Lipophilic derivatives of biologically active compounds
WO2001070642A2 (en) 2000-03-24 2001-09-27 Dsm N.V. Radiation-curable coatings suitable for high-speed application onto optical fibers
GB0017988D0 (en) 2000-07-21 2000-09-13 Glaxo Group Ltd Novel process
GB0202563D0 (en) * 2002-02-04 2002-03-20 Glaxo Group Ltd Process
WO2004033478A2 (en) * 2002-10-08 2004-04-22 Sepracor Inc. Fatty acid modified forms of glucocorticoids and their use as anti-inflammatory
NO331891B1 (no) 2007-03-20 2012-04-30 Clavis Pharma Asa Kjemiske forbindelser, et farmasoytisk preparat inneholdende slike forbindelser, samt anvendelse derav for behandling av kreft, inflammasjon og KOLS

Also Published As

Publication number Publication date
AU2008227246B2 (en) 2012-06-14
CA2680155A1 (en) 2008-09-25
ZA200906226B (en) 2010-05-26
US20100099654A1 (en) 2010-04-22
RU2009138488A (ru) 2011-04-27
JP2010522233A (ja) 2010-07-01
WO2008115069A3 (en) 2008-11-13
RU2462472C2 (ru) 2012-09-27
NO20071485L (no) 2008-09-22
TW200846010A (en) 2008-12-01
CN101687904A (zh) 2010-03-31
EP2121723A2 (en) 2009-11-25
IL200655A0 (en) 2010-05-17
WO2008115069A2 (en) 2008-09-25
UA96794C2 (ru) 2011-12-12
NO331891B1 (no) 2012-04-30
NZ579382A (en) 2011-09-30
US9428540B2 (en) 2016-08-30
TWI428133B (zh) 2014-03-01
JP2014012657A (ja) 2014-01-23
AU2008227246A1 (en) 2008-09-25
KR20090123961A (ko) 2009-12-02

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