PE20050332A1 - Compuestos piperidinicos 1,4-disustituidos como ligandos del neuropeptido y - Google Patents
Compuestos piperidinicos 1,4-disustituidos como ligandos del neuropeptido yInfo
- Publication number
- PE20050332A1 PE20050332A1 PE2004000734A PE2004000734A PE20050332A1 PE 20050332 A1 PE20050332 A1 PE 20050332A1 PE 2004000734 A PE2004000734 A PE 2004000734A PE 2004000734 A PE2004000734 A PE 2004000734A PE 20050332 A1 PE20050332 A1 PE 20050332A1
- Authority
- PE
- Peru
- Prior art keywords
- radical
- cycloaliphatic
- aliphatic
- compounds
- disustituted
- Prior art date
Links
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical class C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 title abstract 2
- 239000003446 ligand Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
- C04B35/622—Forming processes; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
- C04B35/626—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B
- C04B35/63—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B using additives specially adapted for forming the products, e.g.. binder binders
- C04B35/632—Organic additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Ceramic Engineering (AREA)
- Manufacturing & Machinery (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Psychiatry (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Structural Engineering (AREA)
- Inorganic Chemistry (AREA)
- Rheumatology (AREA)
- Materials Engineering (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Nutrition Science (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SE REFIERE A COMPUESTOS PIPERIDINICOS 1,4-DISUSTITUIDOS DE FORMULA I, EN DONDE R1, R2, R3 Y R4 SON, INDEPENDIENTEMENTE ENTRE SI, H, HALOGENO, UN RADICAL ALIFATICO, UN RADICAL CICLOALIFATICO, ENTRE OTROS; R5 ES H, UN RADICAL ALIFATICO o UN RADICAL CICLOALIFATICO; R6, R7, R8 Y R9 SON, INDEPENDIENTEMENTE ENTRE SI, H, UN RADICAL ALIFATICO, UN RADICAL CICLOALIFATICO ENTRE OTROS; A ES CHR18 o CHR18-CH2; B ES UN RADICAL ALIFATICO, UN RADICAL CICLOALIFATICO, ENTRE OTROS; R10 ES H, UN RADICAL ALIFATICO, UN RADICAL CICLOALIFATICO, UN RADICAL ARILO, ENTRE OTROS; R11 ES UN RADICAL ALIFATICO, UN RADICAL CICLOALIFATICO, UN RADICAL ARILO, ENTRE OTROS; O R10 Y R11 JUNTO CON EL ATOMO PUENTE DE N FORMAN UN ANILLO HETEROCICLICO SATURADO, INSATURADO O AROMATICO; R18 ES H, UN RADICAL ALIFATICO, UN RADICAL CICLOALIFATICO, ENTRE OTROS. SON COMPUESTOS PREFERIDOS: 2-[4-(2-HIDROXIMETIL-FENILAMINO)-PIPERIDIN-1-IL]-N-QUINOLIN-3-IL-ACETAMIDA; 2-[4-(2-HIDROXIMETIL-FENILAMINO)-PIPERIDIN-1-IL]-N-QUINOLIN-5-IL-ACETAMIDA; 2-[4-(2-HIDROXIMETIL-FENILAMINO)-PIPERIDIN-1-IL]-N-QUINOLIN-6-IL-ACETAMIDA; ENTRE OTROS. TAMBIEN SE REFIERE A UN PROCESO DE PREPARACION DE ESTOS COMPUESTOS Y UN MEDICAMENTO QUE LOS CONTIENE. ESTOS COMPUESTOS REGULAN LOS RECEPTORES DEL NEUROPEPTIDO Y ESPECIFICAMENTE DEL NEUROPEPTIDO Y5 (NPY5)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200301813A ES2222833B1 (es) | 2003-07-30 | 2003-07-30 | Compuestos piperidinicos 1,4-disustituidos, su preparacion y su uso como medicamentos. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20050332A1 true PE20050332A1 (es) | 2005-06-12 |
Family
ID=34130546
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2004000734A PE20050332A1 (es) | 2003-07-30 | 2004-08-02 | Compuestos piperidinicos 1,4-disustituidos como ligandos del neuropeptido y |
Country Status (19)
| Country | Link |
|---|---|
| US (4) | US20070105853A1 (es) |
| EP (2) | EP1651220B1 (es) |
| JP (2) | JP2007500162A (es) |
| CN (2) | CN1832745A (es) |
| AR (1) | AR045154A1 (es) |
| AT (2) | ATE348614T1 (es) |
| AU (2) | AU2004262482A1 (es) |
| BR (2) | BRPI0413091A (es) |
| CA (2) | CA2534096A1 (es) |
| DE (2) | DE602004003829T2 (es) |
| ES (3) | ES2222833B1 (es) |
| MX (2) | MXPA06001140A (es) |
| MY (1) | MY136965A (es) |
| NO (2) | NO20060553L (es) |
| PE (1) | PE20050332A1 (es) |
| PT (2) | PT1651220E (es) |
| RU (2) | RU2006105792A (es) |
| TW (1) | TW200510379A (es) |
| WO (2) | WO2005013988A1 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9560804B1 (en) | 2010-12-15 | 2017-02-07 | Marion Calmer | Stalk roll with flutes defining a recess |
| ES2222833B1 (es) * | 2003-07-30 | 2006-03-01 | Laboratorios Del Dr. Esteve, S.A. | Compuestos piperidinicos 1,4-disustituidos, su preparacion y su uso como medicamentos. |
| EP1918281A1 (en) * | 2006-11-02 | 2008-05-07 | Laboratorios del Dr. Esteve S.A. | Phenylamino-substituted piperidine compounds, their preparation and use as medicaments |
| WO2008103310A1 (en) | 2007-02-16 | 2008-08-28 | Synta Pharmaceuticals Corp. | Substituted fused-ring compounds for inflammation and immune-related uses |
| WO2010053861A2 (en) * | 2008-11-07 | 2010-05-14 | H. Lundbeck A/S | Biologically active amides |
| US20230295116A1 (en) * | 2020-08-11 | 2023-09-21 | Board Of Trustees Of Michigan State University | Proteasome enhancers and uses thereof |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997019682A1 (en) | 1995-12-01 | 1997-06-05 | Synaptic Pharmaceutical Corporation | Aryl sulfonamide and sulfamide derivatives and uses thereof |
| AU7692996A (en) | 1995-12-01 | 1997-06-27 | Ciba-Geigy Ag | Receptor antagonists |
| DE69720051T2 (de) | 1996-12-03 | 2003-09-04 | Banyu Pharmaceutical Co., Ltd. | Harnstoffderivate |
| US6048900A (en) * | 1998-02-13 | 2000-04-11 | Bayer Corporation | Amide derivatives and methods for using the same as selective neuropeptide Y receptor antagonists |
| AU6144098A (en) * | 1997-02-14 | 1998-09-08 | Bayer Corporation | Amide derivatives as selective neuropeptide y receptor antagonists |
| WO1998040356A1 (en) | 1997-03-12 | 1998-09-17 | Banyu Pharmaceutical Co., Ltd. | Drugs containing aminopyridine derivatives as the active ingredient |
| US7534857B2 (en) * | 1997-12-19 | 2009-05-19 | Centegen, Inc. | Methods and compositions for the treatment and prevention of staphylococcal infections |
| US6187777B1 (en) | 1998-02-06 | 2001-02-13 | Amgen Inc. | Compounds and methods which modulate feeding behavior and related diseases |
| HUP0103887A3 (en) | 1998-10-07 | 2002-06-28 | Ortho Mcneil Pharm Inc | N-aralkylaminotetralins as ligands for the neuropeptide y y5 receptor and pharmaceutical compositions containing such compounds |
| WO2001007409A1 (en) | 1999-07-23 | 2001-02-01 | Astrazeneca Uk Limited | Carbazole derivatives and their use as neuropeptide y5 receptor ligands |
| US6399631B1 (en) | 1999-07-23 | 2002-06-04 | Pfizer Inc. | Carbazole neuropeptide Y5 antagonists |
| HUP0202143A3 (en) * | 1999-07-28 | 2003-12-29 | Ortho Mcneil Pharm Inc | Amine and amide derivatives as ligands for the neuropeptide y y5 receptor pharmaceutical compositions containing them and their use |
| AU769081B2 (en) | 1999-08-26 | 2004-01-15 | Bristol-Myers Squibb Company | NPY antagonists: spiroisoquinolinone derivatives |
| DK1409477T3 (da) * | 2001-07-24 | 2008-12-08 | Richter Gedeon Nyrt | Piperdinderivater som NMDA receptorantagonister |
| US7067549B2 (en) * | 2001-12-31 | 2006-06-27 | Actelion Pharmaceuticals Ag | Pyrrolidone carboxamides |
| ES2193875B2 (es) | 2002-04-09 | 2005-03-01 | Laboratorios Del Dr. Esteve, S.A. | Derivados de benzoxazinona, su preparacion y su aplicacion como medicamentos. |
| ES2222833B1 (es) * | 2003-07-30 | 2006-03-01 | Laboratorios Del Dr. Esteve, S.A. | Compuestos piperidinicos 1,4-disustituidos, su preparacion y su uso como medicamentos. |
| ES2228267B1 (es) * | 2003-07-30 | 2006-07-01 | Laboratorios Del Dr. Esteve, S.A. | Combinacion de sustancias activas conteniendo al menos un compuesto con afinidad por el receptor del neuropeptido y (npy) y al menos un compuesto con afinidad por el receptor 5-ht6. |
-
2003
- 2003-07-30 ES ES200301813A patent/ES2222833B1/es not_active Expired - Fee Related
-
2004
- 2004-07-29 JP JP2006521526A patent/JP2007500162A/ja active Pending
- 2004-07-29 CN CNA2004800222637A patent/CN1832745A/zh active Pending
- 2004-07-29 JP JP2006521533A patent/JP2007500169A/ja active Pending
- 2004-07-29 RU RU2006105792/04A patent/RU2006105792A/ru unknown
- 2004-07-29 AU AU2004262482A patent/AU2004262482A1/en not_active Abandoned
- 2004-07-29 AT AT04763608T patent/ATE348614T1/de not_active IP Right Cessation
- 2004-07-29 WO PCT/EP2004/008508 patent/WO2005013988A1/en not_active Ceased
- 2004-07-29 ES ES04763608T patent/ES2279419T3/es not_active Expired - Lifetime
- 2004-07-29 US US10/566,399 patent/US20070105853A1/en not_active Abandoned
- 2004-07-29 AR ARP040102696A patent/AR045154A1/es unknown
- 2004-07-29 MX MXPA06001140A patent/MXPA06001140A/es not_active Application Discontinuation
- 2004-07-29 AT AT04741322T patent/ATE348615T1/de not_active IP Right Cessation
- 2004-07-29 BR BRPI0413091-0A patent/BRPI0413091A/pt not_active Application Discontinuation
- 2004-07-29 PT PT04741322T patent/PT1651220E/pt unknown
- 2004-07-29 TW TW093122665A patent/TW200510379A/zh unknown
- 2004-07-29 CA CA002534096A patent/CA2534096A1/en not_active Abandoned
- 2004-07-29 AU AU2004262491A patent/AU2004262491A1/en not_active Abandoned
- 2004-07-29 WO PCT/EP2004/008517 patent/WO2005013990A1/en not_active Ceased
- 2004-07-29 DE DE602004003829T patent/DE602004003829T2/de not_active Expired - Lifetime
- 2004-07-29 BR BRPI0412860-5A patent/BRPI0412860A/pt not_active IP Right Cessation
- 2004-07-29 US US10/565,979 patent/US7888510B2/en not_active Expired - Fee Related
- 2004-07-29 EP EP04741322A patent/EP1651220B1/en not_active Expired - Lifetime
- 2004-07-29 MX MXPA06001226A patent/MXPA06001226A/es not_active Application Discontinuation
- 2004-07-29 EP EP04763608A patent/EP1648458B1/en not_active Expired - Lifetime
- 2004-07-29 CN CNA2004800219418A patent/CN1829516A/zh active Pending
- 2004-07-29 MY MYPI20043075A patent/MY136965A/en unknown
- 2004-07-29 CA CA002534101A patent/CA2534101A1/en not_active Abandoned
- 2004-07-29 RU RU2006105711/04A patent/RU2006105711A/ru unknown
- 2004-07-29 ES ES04741322T patent/ES2279400T3/es not_active Expired - Lifetime
- 2004-07-29 PT PT04763608T patent/PT1648458E/pt unknown
- 2004-07-29 DE DE602004003831T patent/DE602004003831T2/de not_active Expired - Lifetime
- 2004-08-02 PE PE2004000734A patent/PE20050332A1/es not_active Application Discontinuation
-
2006
- 2006-02-02 NO NO20060553A patent/NO20060553L/no not_active Application Discontinuation
- 2006-02-07 NO NO20060605A patent/NO20060605L/no not_active Application Discontinuation
-
2010
- 2010-07-12 US US12/834,211 patent/US20100280072A1/en not_active Abandoned
-
2011
- 2011-01-06 US US12/985,646 patent/US20110172270A1/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PE20230238A1 (es) | Inhibidores de kras g12c | |
| PE20040935A1 (es) | Analogos de 2-quinazolina sustituida-4-ilamina como moduladores de los receptores de capsaicina | |
| AR034792A1 (es) | Derivados de 1-fenilsulfonil-1,3-dihidro-2h-indol-2-ona, su preparacion y su aplicacion en terapeutica | |
| PE20040720A1 (es) | Derivados de benzodioxol | |
| CO5590895A2 (es) | Derivados de sulfonamidas, su preparacion y su aplicacion como medicamentos | |
| HUP0300693A2 (hu) | Eljárás epotilon-analógok és -intermedierek előállítására | |
| AR051092A1 (es) | Derivados heterociclicos y su uso como inhibidores de la estearoil-coa | |
| NO20050429L (no) | Substituert kinolin-CCR5-reseptorantagonister | |
| ES2062460T3 (es) | Nuevos derivados de la isoindolona, su preparacion y las composiciones farmaceuticas que les contienen. | |
| AR006720A1 (es) | Un compuesto derivado de azahexano heterociclico, su uso para la preparacion de una composicion farmaceutica, procedimiento para prepararlo y una composicion farmaceutica que lo comprende | |
| PE20070078A1 (es) | Compuestos heterociclicos macrociclicos como inhibidores de aspartil proteasa | |
| AR041395A1 (es) | Compuesto de piridina composicion farmaceutica que lo comprende y su uso para prepararla | |
| PE20081845A1 (es) | Nuevos derivados de aminopirimidina como inhibidores de plk1 | |
| AR052902A1 (es) | Derivados de piridazina, composicion farmaceutica que los contiene y su uso como agentes terapeuticos para enfermedades mediadas por la estearoil-coa desaturasa | |
| PE20050132A1 (es) | Piperazinas heterociclicas sustituidas | |
| CY1108744T1 (el) | 2-οξο-1,2,4,5-τετραϋδρo-1,3-βενζοδιαζεπιν-3-υλ-πιπεριδινες ως ανταγωνιστες της cgrp | |
| AR051202A1 (es) | Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa | |
| PE20081851A1 (es) | Derivados de espiropiperidina-glicinamida | |
| AR048567A1 (es) | Derivados de benzoxazinona, su preparacion y composiciones farmaceuticas. | |
| PE20040757A1 (es) | Derivados de benzoxazina | |
| PE20020063A1 (es) | Bis-arilsulfonas como ligandos del receptor de 5-ht | |
| PE20040698A1 (es) | Derivados de isoindolina | |
| PE20071161A1 (es) | Derivados de urea sustituidos como moduladores del sarcomero cardiaco | |
| NO905368L (no) | Serotonin-antagonister, deres fremstilling og anvendelse. | |
| AR045793A1 (es) | Compuestos derivados de 3-heterociclil-indol |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |