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LT4249073T - Pirimidinai, skirti brutono tirozino kinazės skaidymui - Google Patents

Pirimidinai, skirti brutono tirozino kinazės skaidymui

Info

Publication number
LT4249073T
LT4249073T LTEP23162731.6T LT23162731T LT4249073T LT 4249073 T LT4249073 T LT 4249073T LT 23162731 T LT23162731 T LT 23162731T LT 4249073 T LT4249073 T LT 4249073T
Authority
LT
Lithuania
Prior art keywords
bruton
pyrimidines
degrading
tyrosine kinase
tyrosine
Prior art date
Application number
LTEP23162731.6T
Other languages
English (en)
Inventor
Zhiguo BIAN
Jason Burke
Zhaozhong Jia
Xingyu Jiang
Matthew Katcher
Venkat Reddy Mali
Violeta Marin
Elizabeth Noey
Akinori Okano
Alexey Rivkin
Spencer Scholz
Kevin Woller
Xianrui Zhao
Ashley ADAMS
Berenger BIANNIC
Shahab MORTEZAEI
Joshua Payette
Jeffery Zablocki
Original Assignee
Abbvie Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbvie Inc. filed Critical Abbvie Inc.
Publication of LT4249073T publication Critical patent/LT4249073T/lt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
LTEP23162731.6T 2022-03-22 2023-03-17 Pirimidinai, skirti brutono tirozino kinazės skaidymui LT4249073T (lt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US202263322505P 2022-03-22 2022-03-22

Publications (1)

Publication Number Publication Date
LT4249073T true LT4249073T (lt) 2025-01-27

Family

ID=85776045

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP23162731.6T LT4249073T (lt) 2022-03-22 2023-03-17 Pirimidinai, skirti brutono tirozino kinazės skaidymui

Country Status (22)

Country Link
US (2) US12172992B2 (lt)
EP (2) EP4480482A3 (lt)
JP (1) JP7805983B2 (lt)
KR (1) KR20240163634A (lt)
CN (1) CN119072475A (lt)
AR (1) AR128842A1 (lt)
AU (1) AU2023237882A1 (lt)
CO (1) CO2024012427A2 (lt)
DK (1) DK4249073T3 (lt)
ES (1) ES3014292T3 (lt)
FI (1) FI4249073T3 (lt)
HR (1) HRP20241722T1 (lt)
HU (1) HUE070665T2 (lt)
IL (1) IL314260A (lt)
LT (1) LT4249073T (lt)
MX (1) MX2024011120A (lt)
PL (1) PL4249073T3 (lt)
PT (1) PT4249073T (lt)
RS (1) RS66349B1 (lt)
SI (1) SI4249073T1 (lt)
TW (1) TW202346287A (lt)
WO (1) WO2023183811A1 (lt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118475571A (zh) * 2021-12-30 2024-08-09 百济神州有限公司 通过使布鲁顿酪氨酸激酶(btk)抑制剂与e3连接酶配体缀合来降解btk及使用方法

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CN118475571A (zh) 2021-12-30 2024-08-09 百济神州有限公司 通过使布鲁顿酪氨酸激酶(btk)抑制剂与e3连接酶配体缀合来降解btk及使用方法

Also Published As

Publication number Publication date
RS66349B1 (sr) 2025-01-31
MX2024011120A (es) 2024-09-18
HUE070665T2 (hu) 2025-06-28
PT4249073T (pt) 2025-01-06
FI4249073T3 (fi) 2025-02-03
EP4249073A1 (en) 2023-09-27
PL4249073T3 (pl) 2025-03-17
ES3014292T3 (en) 2025-04-21
AR128842A1 (es) 2024-06-19
CN119072475A (zh) 2024-12-03
JP2023140319A (ja) 2023-10-04
IL314260A (en) 2024-09-01
EP4480482A2 (en) 2024-12-25
US12172992B2 (en) 2024-12-24
WO2023183811A1 (en) 2023-09-28
US20250304568A1 (en) 2025-10-02
US20240109877A1 (en) 2024-04-04
HRP20241722T1 (hr) 2025-02-28
TW202346287A (zh) 2023-12-01
JP7805983B2 (ja) 2026-01-26
SI4249073T1 (sl) 2025-02-28
DK4249073T3 (da) 2025-01-02
CO2024012427A2 (es) 2024-09-30
AU2023237882A1 (en) 2024-08-01
KR20240163634A (ko) 2024-11-19
EP4480482A3 (en) 2025-03-26
EP4249073B1 (en) 2024-12-11

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