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LT2540728T - Heterociklinis junginys - Google Patents

Heterociklinis junginys

Info

Publication number
LT2540728T
LT2540728T LTEP11744685.6T LT11744685T LT2540728T LT 2540728 T LT2540728 T LT 2540728T LT 11744685 T LT11744685 T LT 11744685T LT 2540728 T LT2540728 T LT 2540728T
Authority
LT
Lithuania
Prior art keywords
heterocyclic compound
heterocyclic
compound
Prior art date
Application number
LTEP11744685.6T
Other languages
English (en)
Inventor
Misaki Homma
Toru Miyazaki
Yuya Oguro
Osamu Kurasawa
Original Assignee
Takeda Pharmaceutical Company Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44482985&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LT2540728(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceutical Company Limited filed Critical Takeda Pharmaceutical Company Limited
Publication of LT2540728T publication Critical patent/LT2540728T/lt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/541Non-condensed thiazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/20Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
LTEP11744685.6T 2010-02-17 2011-02-16 Heterociklinis junginys LT2540728T (lt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2010031899 2010-02-17
JP2010131950 2010-06-09
PCT/JP2011/053303 WO2011102399A1 (ja) 2010-02-17 2011-02-16 複素環化合物

Publications (1)

Publication Number Publication Date
LT2540728T true LT2540728T (lt) 2019-06-25

Family

ID=44482985

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP11744685.6T LT2540728T (lt) 2010-02-17 2011-02-16 Heterociklinis junginys

Country Status (37)

Country Link
US (6) US8722660B2 (lt)
EP (2) EP3533797B1 (lt)
JP (1) JP5689454B2 (lt)
KR (1) KR101735868B1 (lt)
CN (1) CN102844320B (lt)
AU (1) AU2011216404B2 (lt)
BR (1) BR112012020311B1 (lt)
CA (1) CA2790284C (lt)
CL (1) CL2012002250A1 (lt)
CO (1) CO6592104A2 (lt)
CR (1) CR20120448A (lt)
CY (1) CY1121792T1 (lt)
DK (1) DK2540728T3 (lt)
DO (1) DOP2012000224A (lt)
EA (1) EA020724B1 (lt)
EC (1) ECSP12012160A (lt)
ES (1) ES2733221T3 (lt)
GE (1) GEP20146202B (lt)
HR (1) HRP20190947T1 (lt)
HU (1) HUE043514T2 (lt)
IL (1) IL221442A0 (lt)
LT (1) LT2540728T (lt)
MA (1) MA34064B1 (lt)
ME (1) ME03410B (lt)
MX (1) MX353500B (lt)
MY (1) MY164776A (lt)
NZ (1) NZ602089A (lt)
PE (1) PE20130184A1 (lt)
PH (1) PH12012501650B1 (lt)
PL (1) PL2540728T3 (lt)
PT (1) PT2540728T (lt)
RS (1) RS58796B1 (lt)
SG (1) SG183304A1 (lt)
SI (1) SI2540728T1 (lt)
SM (1) SMT201900385T1 (lt)
TN (1) TN2012000401A1 (lt)
WO (1) WO2011102399A1 (lt)

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US10174032B2 (en) * 2014-05-05 2019-01-08 Signalrx Pharmaceuticals, Inc. Heterocyclic compound classes for signaling modulation
KR102006320B1 (ko) 2015-12-07 2019-08-02 지머젠 인코포레이티드 Htp 게놈 공학 플랫폼에 의한 미생물 균주 개량
AU2016378723B2 (en) 2015-12-22 2021-09-30 SHY Therapeutics LLC Compounds for the treatment of cancer and inflammatory disease
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EA035560B1 (ru) * 2016-07-28 2020-07-07 Такеда Фармасьютикал Компани Лимитед Кристаллические формы гемигидрата 2-[(2s)-1-азабицикло[2.2.2]окт-2-ил]-6-(3-метил-1h-пиразол-4-ил)тиено[3,2- d]пиримидин-4(3h)-она
JP7071383B2 (ja) 2016-11-08 2022-05-18 キャンサー・リサーチ・テクノロジー・リミテッド cdc7阻害剤としてのピリミジノン誘導体
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TWI846703B (zh) 2018-06-19 2024-07-01 日商武田藥品工業股份有限公司 癌症治療方法
EP3823599B1 (en) * 2018-07-19 2024-08-28 Takeda Pharmaceutical Company Limited Pharmaceutical compositions with a cdc7 inhibitor
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US12391705B2 (en) 2018-12-19 2025-08-19 Shy Therapeutics, Llc Compounds that interact with the Ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease
KR20220027883A (ko) * 2019-05-30 2022-03-08 치아타이 티안큉 파마수티컬 그룹 주식회사 Cdc7 억제제로서의 테트라사이클릭 화합물
BR112022000734A2 (pt) * 2019-07-19 2022-04-12 Takeda Pharmaceuticals Co Método para tratar câncer em um paciente, uso de composto 1, e, composto 1
US20220389026A1 (en) * 2019-08-20 2022-12-08 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Tetracyclic compound used as cdc7 inhibitor
US20230101747A1 (en) * 2019-12-06 2023-03-30 Schrödinger, Inc. Cyclic compounds and methods of using same
WO2022055963A1 (en) * 2020-09-10 2022-03-17 Schrödinger, Inc. Heterocyclic pericondensed cdc7 kinase inhibitors for the treatment of cancer
AU2021386437A1 (en) * 2020-11-30 2023-06-29 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Salt form used as cdc7 inhibitor and crystal form thereof
CN112661770B (zh) * 2020-12-24 2022-11-08 南京正济医药研究有限公司 一种化合物及利用其制备取代的[5,6]环-4(3h)-嘧啶酮化合物的方法
WO2022167999A1 (en) 2021-02-08 2022-08-11 Takeda Pharmaceutical Company Limited Combination therapy for cancer treatment
CN117120447A (zh) * 2021-03-18 2023-11-24 薛定谔公司 环状化合物和其使用方法
TW202300150A (zh) * 2021-03-18 2023-01-01 美商薛定諤公司 環狀化合物及其使用方法
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Also Published As

Publication number Publication date
US8933069B2 (en) 2015-01-13
DK2540728T3 (da) 2019-05-13
EP3533797B1 (en) 2023-12-20
MX353500B (es) 2018-01-16
US20140235615A1 (en) 2014-08-21
MA34064B1 (fr) 2013-03-05
WO2011102399A1 (ja) 2011-08-25
CL2012002250A1 (es) 2013-02-08
CA2790284C (en) 2019-01-08
JPWO2011102399A1 (ja) 2013-06-17
TN2012000401A1 (en) 2014-01-30
PT2540728T (pt) 2019-07-11
ME03410B (me) 2020-01-20
IL221442A0 (en) 2012-10-31
MX2012009602A (es) 2012-12-17
DOP2012000224A (es) 2013-01-31
EP2540728A1 (en) 2013-01-02
US20140228352A1 (en) 2014-08-14
PH12012501650A1 (en) 2012-10-22
CN102844320B (zh) 2016-03-23
NZ602089A (en) 2014-05-30
PE20130184A1 (es) 2013-03-09
CA2790284A1 (en) 2011-08-25
EA201290800A1 (ru) 2013-03-29
SI2540728T1 (sl) 2019-06-28
US20160310494A1 (en) 2016-10-27
CR20120448A (es) 2012-11-13
EP3533797A1 (en) 2019-09-04
ES2733221T3 (es) 2019-11-28
KR20130001246A (ko) 2013-01-03
CN102844320A (zh) 2012-12-26
JP5689454B2 (ja) 2015-03-25
US8921354B2 (en) 2014-12-30
ECSP12012160A (es) 2013-03-28
CY1121792T1 (el) 2020-07-31
US9388195B2 (en) 2016-07-12
GEP20146202B (en) 2014-11-25
PL2540728T3 (pl) 2019-09-30
EP2540728B1 (en) 2019-04-10
US8722660B2 (en) 2014-05-13
US20130029969A1 (en) 2013-01-31
US20170209452A1 (en) 2017-07-27
MY164776A (en) 2018-01-30
US9655900B2 (en) 2017-05-23
RS58796B1 (sr) 2019-07-31
SMT201900385T1 (it) 2019-09-09
HUE043514T2 (hu) 2019-08-28
HRP20190947T1 (hr) 2019-07-26
AU2011216404A1 (en) 2012-09-20
AU2011216404B2 (en) 2016-04-07
CO6592104A2 (es) 2013-01-02
US20150158882A1 (en) 2015-06-11
PH12012501650B1 (en) 2018-11-07
BR112012020311A2 (pt) 2017-03-01
SG183304A1 (en) 2012-09-27
BR112012020311B1 (pt) 2019-01-29
EP2540728A4 (en) 2013-11-06
KR101735868B1 (ko) 2017-05-15
EA020724B1 (ru) 2015-01-30

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