IS7545A - 7-Arýl-3,9-díasabísýkló(3.3.1)nón-6-en afleiður og notkun þeirra sem renín hindra í meðferð á háþrýstingi, hjarta- og æða- eða nýrna sjúkdómum - Google Patents

7-Arýl-3,9-díasabísýkló(3.3.1)nón-6-en afleiður og notkun þeirra sem renín hindra í meðferð á háþrýstingi, hjarta- og æða- eða nýrna sjúkdómum

Info

Publication number: IS7545A
Authority: IS; Iceland
Prior art keywords: renin; diazabicyclo; hypertension; cardiovascular; aryl
Prior art date: 2002-04-29

Application number

IS7545A

Other languages

English (en)

Inventor

Bazencon Olivier

Bur Daniel

Fischli Walter

Remen Lubos

Richard-Bildstein Sylvia

Weber Hans-Peter

Weller Thomas

Original Assignee

Actelion Pharmaceuticals Ltd.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-04-29

Filing date

2004-11-22

Publication date

2004-11-22

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29286070&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IS7545(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2004-11-22 Application filed by Actelion Pharmaceuticals Ltd. filed Critical Actelion Pharmaceuticals Ltd.

2004-11-22 Publication of IS7545A publication Critical patent/IS7545A/is

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4995—Pyrazines or piperazines forming part of bridged ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Cardiology (AREA)
Diabetes (AREA)
Heart & Thoracic Surgery (AREA)
Endocrinology (AREA)
Ophthalmology & Optometry (AREA)
Urology & Nephrology (AREA)
Immunology (AREA)
Vascular Medicine (AREA)
Emergency Medicine (AREA)
Hematology (AREA)
Obesity (AREA)
Gynecology & Obstetrics (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

IS7545A 2002-04-29 2004-11-22 7-Arýl-3,9-díasabísýkló(3.3.1)nón-6-en afleiður og notkun þeirra sem renín hindra í meðferð á háþrýstingi, hjarta- og æða- eða nýrna sjúkdómum IS7545A (is)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP0204705		2002-04-29
PCT/EP2003/003721 WO2003093267A1 (en)	2002-04-29	2003-04-08	7-aryl-3,9-diazabicyclo(3.3.1)non-6-ene derivatives and their use as renin inhibitors in the treatment of hypertension, cardiovascular or renal diseases

Publications (1)

Publication Number	Publication Date
IS7545A true IS7545A (is)	2004-11-22

Family

ID=29286070

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS7545A IS7545A (is)	2002-04-29	2004-11-22	7-Arýl-3,9-díasabísýkló(3.3.1)nón-6-en afleiður og notkun þeirra sem renín hindra í meðferð á háþrýstingi, hjarta- og æða- eða nýrna sjúkdómum

Country Status (26)

Country	Link
US (2)	US7427613B2 (is)
EP (1)	EP1501830B1 (is)
JP (1)	JP4041123B2 (is)
KR (1)	KR100783863B1 (is)
CN (1)	CN1649870A (is)
AT (1)	ATE527261T1 (is)
AU (1)	AU2003233963B2 (is)
BR (1)	BR0309498A (is)
CA (1)	CA2483241C (is)
CL (1)	CL2003002042A1 (is)
CO (1)	CO5631443A2 (is)
EC (1)	ECSP045378A (is)
ES (1)	ES2372931T3 (is)
HR (1)	HRP20041132A2 (is)
IL (1)	IL164767A0 (is)
IS (1)	IS7545A (is)
MA (1)	MA27305A1 (is)
MX (1)	MXPA04010608A (is)
NO (1)	NO20045042L (is)
NZ (1)	NZ536750A (is)
PL (1)	PL372141A1 (is)
RU (1)	RU2343153C2 (is)
TW (1)	TW200514786A (is)
UA (1)	UA80821C2 (is)
WO (1)	WO2003093267A1 (is)
ZA (1)	ZA200408283B (is)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20060217371A1 (en) *	2003-04-28	2006-09-28	Olivier Bezencon	Diazabicyclononene and tetrahydropyriddine derivatives as renin inhibitors
US20060258648A1 (en) *	2003-04-30	2006-11-16	Olivier Bezencon	9-Azabicyclo'3.3.1 inon-6-ee derivatives with a heteroatom at the 3-position as renin inhibitors
JP2006524657A (ja) *	2003-04-30	2006-11-02	アクテリオン　ファマシューティカルズ　リミテッド	新規トロパン誘導体
MXPA05011496A (es) *	2003-04-30	2005-12-15	Actelion Pharmaceuticals Ltd	Derivados de azabiciclononeno.
EP1622564A2 (en) *	2003-05-02	2006-02-08	Actelion Pharmaceuticals Ltd.	Diazabicyclononene derivatives
WO2004105762A1 (en) *	2003-05-30	2004-12-09	Actelion Pharmaceuticals Ltd	Medical use of diazabicyclononene derivatives as inhibitors of parasite aspartic proteases
US20080234305A1 (en) *	2003-10-09	2008-09-25	Olivier Bezencon	Novel Tetrahydropyridine Derivatives
WO2005040165A1 (en) *	2003-10-13	2005-05-06	Actelion Pharmaceuticals Ltd	Diazabicyclononene derivatives and their use as renin inhibitors
US20070135405A1 (en) *	2003-10-23	2007-06-14	Olivier Bezencon	Novel diazabicyclononene and tetrahydropyridine derivatives with a new polar side-chain
CN1890240A (zh) *	2003-12-05	2007-01-03	埃科特莱茵药品有限公司	二氮杂二环壬烯衍生物及其作为血管紧张肽原酶抑制剂的用途
JP2007513107A (ja) *	2003-12-05	2007-05-24	アクテリオン　ファマシューティカルズ　リミテッド	ジアザビシクロノネンおよび新側鎖を有するテトラヒドロピリジン誘導体
WO2006021403A1 (en) *	2004-08-25	2006-03-02	Actelion Pharmaceuticals Ltd	Bicyclononene derivatives
DE602005020314D1 (de) *	2004-08-25	2010-05-12	Actelion Pharmaceuticals Ltd	Bicyclononen-derivate als renin-inhibitoren
WO2006021401A2 (en) *	2004-08-25	2006-03-02	Actelion Pharmaceuticals Ltd	Bicylononene derivatives
WO2006021399A2 (en) *	2004-08-25	2006-03-02	Actelion Pharmaceuticals Ltd	Azabicyclononene derivatives as renin inhibitors
AR052263A1 (es) *	2004-12-08	2007-03-07	Actelion Pharmaceuticals Ltd	Derivado de diazabiciclononeno
WO2006063610A1 (en) *	2004-12-17	2006-06-22	Actelion Pharmaceuticals Ltd	Heteroaryl substituted diazabicyclononene derivatives
GB0428526D0 (en)	2004-12-30	2005-02-09	Novartis Ag	Organic compounds
RU2007132438A (ru) *	2005-01-28	2009-03-10	Актелион Фармасьютикалз Лтд (Ch)	Циклопропил-(2,3-диметилбензил)амид 7-{4-[2-(2,6-дихлор-4-метилфенокси)этокси]фенил}-3,9-диазабицикло[3.3.1]нон-6-ен-6-карбоновой кислоты в качестве ингибиторов ренина для лечения артериальной гипертензии
US7799805B2 (en)	2005-05-27	2010-09-21	Actelion Pharmaceuticals Ltd.	Piperidine carboxylic acid amide derivatives
GB0514203D0 (en)	2005-07-11	2005-08-17	Novartis Ag	Organic compounds
PT2420491E (pt)	2005-12-30	2013-10-14	Novartis Ag	Compostos de piperidina 3,5-substituída como inibidores de renina
JP2009526767A (ja)	2006-02-02	2009-07-23	アクテリオンファーマシューティカルズリミテッド	新規二級アミン
WO2007102127A2 (en) *	2006-03-08	2007-09-13	Actelion Pharmaceuticals Ltd	New amines
US8343968B2 (en)	2007-05-24	2013-01-01	Merck Canada Inc.	Case of renin inhibitors
ES2541107T3 (es)	2007-06-25	2015-07-16	Novartis Ag	Derivados de N5-(2-etoxietil)-N3-(2-piridinil)-3,5-piperidindicarboxamida para su uso como inhibidores de renina
WO2009023964A1 (en)	2007-08-20	2009-02-26	Merck Frosst Canada Ltd.	Renin inhibitors
JP4790871B2 (ja)	2008-05-05	2011-10-12	メルクフロストカナダリミテツド	レニン阻害剤としての３，４−置換ピペリジン誘導体
CN109721613B (zh) *	2017-10-27	2021-07-30	四川科伦博泰生物医药股份有限公司	含季铵离子的大环酰胺化合物及其药物组合物和用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3509161A (en) *	1967-07-10	1970-04-28	Boehringer & Soehne Gmbh	3-phenyl-granatene-(2)-derivatives
GB9020927D0 (en)	1990-09-26	1990-11-07	Beecham Group Plc	Pharmaceuticals
US5268361A (en) *	1991-06-07	1993-12-07	Sri International	Hydroxyazido derivatives and related compounds as renin inhibitors
US5374719A (en) *	1993-06-04	1994-12-20	Eli Lilly And Company	Process for converting loracarbef dihydrate to loracarbef monohydrate
PL193686B1 (pl)	1995-09-07	2007-03-30	Hoffmann La Roche	Pochodne piperydyny, środki lecznicze zawierającepochodne piperydyny, sposoby wytwarzania tych pochodnych oraz zastosowanie pochodnych
EP0966464B1 (en)	1997-03-03	2003-05-28	Basilea Pharmaceutica AG	Substituted 2,4-diaminopyrimidines
US20060223795A1 (en) *	2003-05-02	2006-10-05	Oliver Bezencon	Novel diazabicyclononene derivatives
CN1890240A (zh) *	2003-12-05	2007-01-03	埃科特莱茵药品有限公司	二氮杂二环壬烯衍生物及其作为血管紧张肽原酶抑制剂的用途

2003
- 2003-04-08 ES ES03727287T patent/ES2372931T3/es not_active Expired - Lifetime
- 2003-04-08 US US10/513,103 patent/US7427613B2/en not_active Expired - Fee Related
- 2003-04-08 PL PL03372141A patent/PL372141A1/xx not_active Application Discontinuation
- 2003-04-08 IL IL16476703A patent/IL164767A0/xx unknown
- 2003-04-08 NZ NZ536750A patent/NZ536750A/xx unknown
- 2003-04-08 AU AU2003233963A patent/AU2003233963B2/en not_active Ceased
- 2003-04-08 WO PCT/EP2003/003721 patent/WO2003093267A1/en not_active Ceased
- 2003-04-08 AT AT03727287T patent/ATE527261T1/de not_active IP Right Cessation
- 2003-04-08 CA CA2483241A patent/CA2483241C/en not_active Expired - Fee Related
- 2003-04-08 MX MXPA04010608A patent/MXPA04010608A/es not_active Application Discontinuation
- 2003-04-08 HR HR20041132A patent/HRP20041132A2/xx not_active Application Discontinuation
- 2003-04-08 CN CNA038097664A patent/CN1649870A/zh active Pending
- 2003-04-08 EP EP03727287A patent/EP1501830B1/en not_active Expired - Lifetime
- 2003-04-08 JP JP2004501406A patent/JP4041123B2/ja not_active Expired - Fee Related
- 2003-04-08 BR BR0309498-7A patent/BR0309498A/pt not_active IP Right Cessation
- 2003-04-08 RU RU2004134320/04A patent/RU2343153C2/ru not_active IP Right Cessation
- 2003-04-08 KR KR1020047016845A patent/KR100783863B1/ko not_active Expired - Fee Related
- 2003-08-04 UA UA20041109469A patent/UA80821C2/uk unknown
- 2003-10-10 CL CL200302042A patent/CL2003002042A1/es unknown
- 2003-10-23 TW TW092129421A patent/TW200514786A/zh unknown
2004
- 2004-10-13 ZA ZA200408283A patent/ZA200408283B/xx unknown
- 2004-10-22 MA MA27914A patent/MA27305A1/fr unknown
- 2004-10-22 EC EC2004005378A patent/ECSP045378A/es unknown
- 2004-10-22 CO CO04106347A patent/CO5631443A2/es not_active Application Discontinuation
- 2004-11-19 NO NO20045042A patent/NO20045042L/no not_active Application Discontinuation
- 2004-11-22 IS IS7545A patent/IS7545A/is unknown
2008
- 2008-07-07 US US12/168,666 patent/US20080312242A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP1501830B1 (en)	2011-10-05
US20080312242A1 (en)	2008-12-18
CO5631443A2 (es)	2006-04-28
HRP20041132A2 (en)	2006-07-31
BR0309498A (pt)	2005-02-15
JP4041123B2 (ja)	2008-01-30
CA2483241C (en)	2011-05-31
UA80821C2 (en)	2007-11-12
PL372141A1 (en)	2005-07-11
CN1649870A (zh)	2005-08-03
KR20040101546A (ko)	2004-12-02
NZ536750A (en)	2007-02-23
TW200514786A (en)	2005-05-01
RU2004134320A (ru)	2005-08-27
WO2003093267A1 (en)	2003-11-13
CA2483241A1 (en)	2003-11-13
KR100783863B1 (ko)	2007-12-10
AU2003233963B2 (en)	2008-09-11
EP1501830A1 (en)	2005-02-02
RU2343153C2 (ru)	2009-01-10
AU2003233963A1 (en)	2003-11-17
ATE527261T1 (de)	2011-10-15
IL164767A0 (en)	2005-12-18
MA27305A1 (fr)	2005-05-02
US7427613B2 (en)	2008-09-23
ES2372931T3 (es)	2012-01-27
CL2003002042A1 (es)	2005-02-04
US20050176700A1 (en)	2005-08-11
MXPA04010608A (es)	2004-12-13
NO20045042L (no)	2004-11-19
ECSP045378A (es)	2004-11-26
ZA200408283B (en)	2006-05-31
JP2005527602A (ja)	2005-09-15

Publication	Publication Date	Title
IS7545A (is)	2004-11-22	7-Arýl-3,9-díasabísýkló(3.3.1)nón-6-en afleiður og notkun þeirra sem renín hindra í meðferð á háþrýstingi, hjarta- og æða- eða nýrna sjúkdómum
TW200514772A (en)	2005-05-01	Novel tetrahydropyridine derivatives
IS7965A (is)	2005-07-29	Þíenópýrimidíndíón og notkun þeirra í breytingu ásjálfsnæmissjúkdómi
IL187438A0 (en)	2008-02-09	Pyrrolopyridine derivatives and pharmaceutical compositions containing the same
WO2004046120A3 (en)	2004-08-12	Diaminotriazoles useful as inhibitors of protein kinases
WO2001087882A3 (en)	2002-05-23	Substituted pyrrolopyridinone derivatives useful as phosphodiesterase inhibitors
YU87202A (sh)	2006-05-25	Derivati arilmetilamina koji se koriste kao inhibitori triptaze
TNSN07435A1 (en)	2009-03-17	Novel piperidine carboxylic acid amide derivatives
MXPA05011711A (es)	2006-01-23	Derivados de diazabiciclononeno.
MXPA05011496A (es)	2005-12-15	Derivados de azabiciclononeno.
MXPA05011498A (es)	2005-12-15	Derivados de 9-azabiciclo[3.3.1]non-6-eno con un heteroatomo en la posicion 3 como inhibidores de renina.
WO2005030209A8 (en)	2006-05-11	Pyridine derivatives and use thereof as urotensin ii antagonists
MXPA04002282A (es)	2005-03-07	Nuevos compuestos y preparaciones como inhibidores de la catepsina.
MXPA05011497A (es)	2005-12-15	Derivados de tropano y su uso como inhibidores de la enzima de conversion de angiotensina (ace).
TW200621773A (en)	2006-07-01	Bicyclononene derivatives
WO2003080631A8 (en)	2004-06-10	Plasma carboxypeptidase b inhibitors
TW200628468A (en)	2006-08-16	Bicyclononene derivatives
TW200621774A (en)	2006-07-01	Bicyclononene derivatives
SG146685A1 (en)	2008-10-30	Dihydroporphine derivatives, processes for their preparation, and pharmaceutical compositions containing them
WO2006021399A3 (en)	2006-10-26	Azabicyclononene derivatives as renin inhibitors
MX2007006745A (es)	2007-07-09	Nuevo derivado de diazabiciclononeno.
WO2004054983A3 (en)	2004-08-05	1-n-phenylamino-1h-imidazole derivatives as aromatase inhibitors
WO2006059304A3 (en)	2006-10-12	Novel lactame derivatives as renin inhibitors
MXPA05014081A (es)	2006-03-09	Derivados de benzofurano y su uso en el tratamiento de infecciones microbianas.
UA95909C2 (en)	2011-09-26	Piperidine carboxylic acid amide derivatives