IN185328B - - Google Patents

Info

Publication number: IN185328B
Authority: IN; India

Application number

Other languages

English (en)

Inventor

Gerard Gal Claudine Se Valette

Original Assignee

Sanofi Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-10-24

Filing date

1996-10-23

Publication date

2000-12-30

1996-10-23 Application filed by Sanofi Sa filed Critical Sanofi Sa

2000-12-30 Publication of IN185328B publication Critical patent/IN185328B/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/96—Spiro-condensed ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Diabetes (AREA)
Biomedical Technology (AREA)
Ophthalmology & Optometry (AREA)
Cardiology (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Psychiatry (AREA)
Endocrinology (AREA)
Addiction (AREA)
Urology & Nephrology (AREA)
Obesity (AREA)
Hospice & Palliative Care (AREA)
Gastroenterology & Hepatology (AREA)
Vascular Medicine (AREA)
Pain & Pain Management (AREA)
Pulmonology (AREA)
Emergency Medicine (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

IN2288DE1996 1995-10-24 1996-10-23 IN185328B (is)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9512533A FR2740136B1 (fr)	1995-10-24	1995-10-24	Derives d'indolin-2-one, procede pour leur preparation et les compositions pharmaceutiques les contenant

Publications (1)

Publication Number	Publication Date
IN185328B true IN185328B (is)	2000-12-30

Family

ID=9483867

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IN2288DE1996 IN185328B (is)	1995-10-24	1996-10-23

Country Status (30)

Country	Link
US (2)	US5994350A (is)
EP (1)	EP0873309B1 (is)
JP (2)	JP3274471B2 (is)
KR (1)	KR100298925B1 (is)
CN (1)	CN1106384C (is)
AR (1)	AR004225A1 (is)
AT (1)	ATE229940T1 (is)
AU (1)	AU715841B2 (is)
BR (1)	BR9611198A (is)
CZ (1)	CZ295585B6 (is)
DE (1)	DE69625517T2 (is)
DK (1)	DK0873309T3 (is)
EE (1)	EE04433B1 (is)
ES (1)	ES2191769T3 (is)
FR (1)	FR2740136B1 (is)
HU (1)	HUP9900331A3 (is)
IL (1)	IL124002A (is)
IN (1)	IN185328B (is)
IS (1)	IS1949B (is)
MY (1)	MY115864A (is)
NO (1)	NO310974B1 (is)
NZ (1)	NZ320352A (is)
PL (1)	PL187093B1 (is)
RU (1)	RU2167864C2 (is)
SK (1)	SK284546B6 (is)
TR (1)	TR199800719T2 (is)
TW (1)	TW474917B (is)
UA (1)	UA59345C2 (is)
WO (1)	WO1997015556A1 (is)
ZA (1)	ZA968945B (is)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2757157B1 (fr) *	1996-12-13	1999-12-31	Sanofi Sa	Derives d'indolin-2-one, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2775598A1 (fr)	1998-03-06	1999-09-10	Sanofi Sa	Compositions pharmaceutiques contenant en association un antagoniste selectif des recepteurs v1a de l'arginine-vasopressine et un antagoniste selectif des recepteur v2 de l'arginine-vasopressine
FR2778103A1 (fr) *	1998-04-29	1999-11-05	Sanofi Sa	Compositions pharmaceutiques contenant en association un antagoniste v1a de l'arginine-vasopressine et un antagoniste des recepteurs at1 de l'angiotensine ii
HU225150B1 (en)	1999-07-15	2006-07-28	Sanofi Aventis	Novel process for producing 2-methoxy-4-(t-butylaminocarbonyl)-benzenesulfonyl chloride
HUP9902374A3 (en) *	1999-07-15	2002-11-28	Sanofi Aventis	Process for producing spiro[(4-cyclohexanone)-[3h]indol-2'[1'h]-on derivatives and intermediates
HU225703B1 (en) *	1999-07-15	2007-06-28	Sanofi Aventis	Process for producing spiro[cis-4-(betha-hydroxy-ethyloxi)-cyclohexane-[3h]indole]-2'[1'h]-one derivatives
HUP9902376A3 (en)	1999-07-15	2002-11-28	Sanofi Aventis	Process for producing n-(1,1-dimethyl)-4-[[s'-ethoxi-4-cis-[2-(4-morpholino)-ethoxi]-2'-oxospiro[cyclohexane-1,3'-[3h]indole]-1'(2'h)yl]-sulfonyl]-3-methoxybenzamide and its salts
US20030103983A1 (en) *	2002-05-09	2003-06-05	Pressler Milton Lethan	Ace inhibitor-vasopressin antagonist combinations
WO2002044179A1 (en) *	2000-11-28	2002-06-06	Yamanouchi Pharmaceutical Co., Ltd.	1,4,5,6-tetrahydroimidazo[4,5-d]diazepine derivatives or salts thereof
WO2002047679A2 (en) *	2000-12-15	2002-06-20	Emory University	Nonpeptide agonists and antagonists of vasopressin receptors
AU2002247127A1 (en)	2001-02-14	2002-08-28	Duke University	Therapy for cerebral vasospasm
JP4520145B2 (ja) *	2001-07-31	2010-08-04	サノフィ−アベンティス	３−スピロ［シクロヘキサン−１，３’−［３ｈ］インドリン］−２’−オン誘導体の調製のための方法
US7414052B2 (en)	2004-03-30	2008-08-19	Wyeth	Phenylaminopropanol derivatives and methods of their use
US7517899B2 (en)	2004-03-30	2009-04-14	Wyeth	Phenylaminopropanol derivatives and methods of their use
CA2568640C (en)	2004-06-04	2011-08-09	Teva Pharmaceutical Industries Ltd.	Pharmaceutical composition containing irbesartan
FR2874920B1 (fr) *	2004-09-09	2006-10-20	Sanofi Aventis Sa	Derives de 3-spiro-indolin-2-one comme ligand des recepteurs de la vasopressine
FR2874921B1 (fr) *	2004-09-09	2006-10-20	Sanofi Aventis Sa	Derives de 3-spiro-indolin-2-one, leur preparation et leur application en therapeutique
BRPI0519013A2 (pt) *	2004-12-13	2009-11-03	Lilly Co Eli	composto ou esteroisÈmeros únicos, misturas de esteroisÈmeros, sais, tautÈmeros ou pró-drogas destes farmaceuticamente aceitáveis, composição farmacêutica, e, uso de um composto
US20120115842A1 (en) *	2004-12-31	2012-05-10	Wilfried Lubisch	Substituted Oxindole Derivatives, Medicaments Containing Said Derivatives and Use Thereof
DE102005014936A1 (de) *	2005-03-24	2006-12-14	Abbott Gmbh & Co. Kg	Substituierte Oxindol-Derivate, diese enthaltende Arzneimittel und deren Verwendung
MY158766A (en)	2005-04-11	2016-11-15	Xenon Pharmaceuticals Inc	Spiro-oxindole compounds and their uses as therapeutic agents
AR053710A1 (es) *	2005-04-11	2007-05-16	Xenon Pharmaceuticals Inc	Compuestos espiroheterociclicos y sus usos como agentes terapeuticos
AR056317A1 (es) *	2005-04-20	2007-10-03	Xenon Pharmaceuticals Inc	Compuestos de oxindol y composicion farmaceutica
US7351706B2 (en) *	2006-01-05	2008-04-01	Hoffmann-La Roche Inc.	Indol-3-yl-carbonyl-spiro-piperidine derivatives
JP5460324B2 (ja) *	2006-10-12	2014-04-02	ゼノン・ファーマシューティカルズ・インコーポレイテッド	治療剤としてのスピロ−オキシインドール化合物の使用
CL2007002953A1 (es) *	2006-10-12	2008-02-01	Xenon Pharmaceuticals Inc	Compuestos derivados de espiro-oxindol; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto en el tratamiento del dolor, cancer, prurito, hiperplasia prostatica benigna, hipercolesterolemia.
CN101522685A (zh) *	2006-10-12	2009-09-02	泽农医药公司	三环螺-吲哚酮衍生物及其作为治疗剂的用途
FR2927625B1 (fr)	2008-02-19	2010-03-12	Sanofi Aventis	Nouveaux derives de 3-aminoalkyl-1,3-dihydro-2h-indol-2-one, leur preparation et leur application en therapeutique
US7723372B2 (en)	2008-03-19	2010-05-25	Hoffman-La Roche Inc.	Spiroindolinone derivatives
FR2930249B1 (fr)	2008-04-21	2010-05-14	Sanofi Aventis	Nouveaux derives de 3-aminoalkyl-1,3-dihydro-2h-indol-2-one, leur preparation et leur application en therapeutique.
JP5570172B2 (ja) *	2008-10-08	2014-08-13	持田製薬株式会社	喫煙による循環機能不全の予防／改善または治療剤
CN105218565A (zh)	2008-10-17	2016-01-06	泽农医药公司	螺羟吲哚化合物及其作为治疗剂的用途
WO2010045197A1 (en) *	2008-10-17	2010-04-22	Xenon Pharmaceuticals, Inc.	Spiro-oxindole compounds and their use as therapeutic agents
AR077252A1 (es)	2009-06-29	2011-08-10	Xenon Pharmaceuticals Inc	Enantiomeros de compuestos de espirooxindol y sus usos como agentes terapeuticos
WO2011047173A2 (en) *	2009-10-14	2011-04-21	Xenon Pharmaceuticals Inc.	Pharmaceutical compositions for oral administration
US8445696B2 (en)	2009-10-14	2013-05-21	Xenon Pharmaceuticals Inc.	Synthetic methods for spiro-oxindole compounds
US8088815B2 (en)	2009-12-02	2012-01-03	Hoffman-La Roche Inc.	Spiroindolinone pyrrolidines
US8288431B2 (en)	2010-02-17	2012-10-16	Hoffmann-La Roche Inc.	Substituted spiroindolinones
CA2788440A1 (en)	2010-02-26	2011-09-01	Xenon Pharmaceuticals Inc.	Pharmaceutical compositions of spiro-oxindole compound for topical administration and their use as therapeutic agents
US8217044B2 (en)	2010-04-28	2012-07-10	Hoffmann-La Roche Inc.	Spiroindolinone pyrrolidines
MD4202C1 (ro) *	2012-03-21	2013-09-30	Институт Химии Академии Наук Молдовы	Procedeu de obţinere a derivaţilor carbometoxi ai spiro[ciclopropan-oxindolilor]
MD4201C1 (ro) *	2012-03-21	2013-09-30	Институт Химии Академии Наук Молдовы	Procedeu de obţinere a derivaţilor carbonitrilici ai spiro[ciclopropan-oxindolilor]
MX382981B (es) *	2013-03-08	2025-03-12	Wockhardt Ltd	Proceso para la preparacion de (2s, 5r)-7-oxo-6-sulfooxi-2-[((3r)-piperidin-3-carbonil)carbonil hidrazino]-1,6-diaza-biciclo[3.2.1] -octano.
AR103636A1 (es)	2015-02-05	2017-05-24	Teva Pharmaceuticals Int Gmbh	Métodos de tratamiento de neuralgia postherpética con una formulación tópica de un compuesto de espiro-oxindol
TW201938171A (zh)	2017-12-15	2019-10-01	匈牙利商羅特格登公司	作為血管升壓素Ｖ１ａ受體拮抗劑之三環化合物
HU231206B1 (hu)	2017-12-15	2021-10-28	Richter Gedeon Nyrt.	Triazolobenzazepinek

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3818830A1 (de) *	1988-06-03	1989-12-14	Boehringer Mannheim Gmbh	Bicyclische carboxamide, verfahren zu ihrer herstellung, deren vorstufen, und diese verbindungen enthaltende arzneimittel
FR2686878B1 (fr) *	1992-01-30	1995-06-30	Sanofi Elf	Derives du n-sulfonyl oxo-2 indole, leur preparation, les compositions pharmaceutiques en contenant.
US5663431A (en) *	1992-01-30	1997-09-02	Sanofi	1-benzenesulfonyl-1,3-dihydro-indol-2-one derivatives, their preparation and pharmaceutical compositions in which they are present
FR2708605A1 (fr) *	1993-07-30	1995-02-10	Sanofi Sa	Dérivés du N-sulfonylindol-2-one, leur préparation, les compositions pharmaceutiques en contenant.
US5686624A (en) *	1992-01-30	1997-11-11	Sanofi	1-benzenesulfonyl-1,3-dihydro-indol-2-one derivatives, their preparation and pharmaceutical compositions in which they are present
FR2708606B1 (fr) *	1993-07-30	1995-10-27	Sanofi Sa	Dérivés du N-phénylalkylindol-2-one, leur préparation, les compositions pharmaceutiques en contenant.

1995
- 1995-10-24 FR FR9512533A patent/FR2740136B1/fr not_active Expired - Fee Related
1996
- 1996-10-22 TW TW085112955A patent/TW474917B/zh not_active IP Right Cessation
- 1996-10-23 AR ARP960104863A patent/AR004225A1/es active IP Right Grant
- 1996-10-23 IN IN2288DE1996 patent/IN185328B/en unknown
- 1996-10-23 MY MYPI96004404A patent/MY115864A/en unknown
- 1996-10-24 BR BR9611198A patent/BR9611198A/pt not_active IP Right Cessation
- 1996-10-24 HU HU9900331A patent/HUP9900331A3/hu unknown
- 1996-10-24 CZ CZ19981267A patent/CZ295585B6/cs not_active IP Right Cessation
- 1996-10-24 AT AT96934967T patent/ATE229940T1/de active
- 1996-10-24 KR KR1019980702996A patent/KR100298925B1/ko not_active Expired - Fee Related
- 1996-10-24 ZA ZA968945A patent/ZA968945B/xx unknown
- 1996-10-24 TR TR1998/00719T patent/TR199800719T2/xx unknown
- 1996-10-24 ES ES96934967T patent/ES2191769T3/es not_active Expired - Lifetime
- 1996-10-24 EP EP96934967A patent/EP0873309B1/fr not_active Expired - Lifetime
- 1996-10-24 PL PL96326555A patent/PL187093B1/pl not_active IP Right Cessation
- 1996-10-24 SK SK490-98A patent/SK284546B6/sk not_active IP Right Cessation
- 1996-10-24 WO PCT/FR1996/001666 patent/WO1997015556A1/fr not_active Ceased
- 1996-10-24 AU AU73080/96A patent/AU715841B2/en not_active Ceased
- 1996-10-24 JP JP51636397A patent/JP3274471B2/ja not_active Expired - Fee Related
- 1996-10-24 US US09/051,900 patent/US5994350A/en not_active Expired - Lifetime
- 1996-10-24 UA UA98042064A patent/UA59345C2/uk unknown
- 1996-10-24 DK DK96934967T patent/DK0873309T3/da active
- 1996-10-24 RU RU98109945/04A patent/RU2167864C2/ru not_active IP Right Cessation
- 1996-10-24 CN CN96198579A patent/CN1106384C/zh not_active Expired - Fee Related
- 1996-10-24 DE DE69625517T patent/DE69625517T2/de not_active Expired - Lifetime
- 1996-10-24 EE EE9800151A patent/EE04433B1/xx not_active IP Right Cessation
- 1996-10-24 NZ NZ320352A patent/NZ320352A/xx not_active IP Right Cessation
- 1996-10-24 IL IL12400296A patent/IL124002A/en not_active IP Right Cessation
1998
- 1998-04-14 IS IS4714A patent/IS1949B/is unknown
- 1998-04-23 NO NO19981817A patent/NO310974B1/no not_active IP Right Cessation
1999
- 1999-10-12 US US09/417,190 patent/US6046341A/en not_active Expired - Lifetime
2001
- 2001-03-16 JP JP2001075467A patent/JP2001302631A/ja active Pending

Also Published As

Publication number	Publication date
ES2191769T3 (es)	2003-09-16
ATE229940T1 (de)	2003-01-15
RU2167864C2 (ru)	2001-05-27
IS1949B (is)	2004-10-13
CN1202886A (zh)	1998-12-23
MX9803269A (es)	1998-09-30
HUP9900331A2 (hu)	1999-05-28
PL187093B1 (pl)	2004-05-31
NO981817L (no)	1998-04-23
EP0873309B1 (fr)	2002-12-18
WO1997015556A1 (fr)	1997-05-01
US6046341A (en)	2000-04-04
BR9611198A (pt)	1999-04-06
TR199800719T2 (xx)	1998-08-21
IL124002A (en)	2002-11-10
IS4714A (is)	1998-04-14
AU715841B2 (en)	2000-02-10
CZ295585B6 (cs)	2005-08-17
UA59345C2 (uk)	2003-09-15
SK49098A3 (en)	1998-09-09
DE69625517T2 (de)	2003-09-11
KR19990067056A (ko)	1999-08-16
AR004225A1 (es)	1998-11-04
JPH11509232A (ja)	1999-08-17
NZ320352A (en)	2000-01-28
US5994350A (en)	1999-11-30
DK0873309T3 (da)	2003-03-17
DE69625517D1 (de)	2003-01-30
NO981817D0 (no)	1998-04-23
TW474917B (en)	2002-02-01
CZ126798A3 (cs)	1998-08-12
EE9800151A (et)	1998-12-15
KR100298925B1 (ko)	2001-09-06
AU7308096A (en)	1997-05-15
PL326555A1 (en)	1998-09-28
EP0873309A1 (fr)	1998-10-28
JP2001302631A (ja)	2001-10-31
FR2740136B1 (fr)	1998-01-09
SK284546B6 (sk)	2005-06-02
HUP9900331A3 (en)	1999-11-29
JP3274471B2 (ja)	2002-04-15
EE04433B1 (et)	2005-02-15
HK1016596A1 (en)	1999-11-05
MY115864A (en)	2003-09-30
CN1106384C (zh)	2003-04-23
FR2740136A1 (fr)	1997-04-25
ZA968945B (en)	1997-05-29
NO310974B1 (no)	2001-09-24

Publication	Publication Date	Title
BR122012014331A2 (is)	1999-01-05
BRPI9612258B1 (is)	2011-05-31
EP0771696A3 (is)	1997-06-18
FR11C0007I1 (is)	2011-04-22
BRPI9612138B1 (is)	2009-09-22
IN185328B (is)	2000-12-30
IN187598B (is)	2002-05-25
CH0741373H1 (is)	2011-10-14
IN186068B (is)	2001-06-16
BR7501503U (is)	1997-11-25
IN184880B (is)	2000-09-30
IN183334B (is)	1999-11-20
IN182569B (is)	1999-05-08
IN183587B (is)	2000-02-19
AU1627395A (is)	1995-06-30
ECSDI950293S (is)	1997-06-27
IN184189B (is)	2000-07-01
BR7502120U (is)	1998-04-14
IN184588B (is)	2000-09-09
CN3035870S (is)	1995-10-04
CN3035868S (is)	1995-10-04
EP0726193A3 (is)	1996-09-04
CN3034829S (is)	1995-09-06
CN3031655S (is)	1995-05-10
CN3029801S (is)	1995-01-25