HUP0101545A1 - Peptideket időben elnyújtva kibocsátó gyógyászati készítmények és eljárás az előállításukra - Google Patents
Peptideket időben elnyújtva kibocsátó gyógyászati készítmények és eljárás az előállításukraInfo
- Publication number
- HUP0101545A1 HUP0101545A1 HU0101545A HUP0101545A HUP0101545A1 HU P0101545 A1 HUP0101545 A1 HU P0101545A1 HU 0101545 A HU0101545 A HU 0101545A HU P0101545 A HUP0101545 A HU P0101545A HU P0101545 A1 HUP0101545 A1 HU P0101545A1
- Authority
- HU
- Hungary
- Prior art keywords
- preparation
- pharmaceutical compositions
- release
- peptide release
- patient
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 238000002360 preparation method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000002035 prolonged effect Effects 0.000 title 1
- 239000000499 gel Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000007787 solid Substances 0.000 abstract 2
- 239000011230 binding agent Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Abstract
A találmány új, peptideket időben elnyújtva kibocsátó gyógyászatikészítményekre és az előállításukra vonatkozó eljárásra vonatkozik. Agélesedő és vízoldékony peptid sót valamint adott esetben alkalmaskötőanyagot tartalmazó szilárd vagy félszilárd gyógyászatikészítményben a peptid só nagy fajlagos felülettel rendelkezik, és abetegbe injektálva a beteg testének anyagaival érintkezve gélesedik,amely gél a peptidet időben elnyújtva, legalább 15 napon át képeskibocsátani. Ó
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9803667A FR2776520B1 (fr) | 1998-03-25 | 1998-03-25 | Nouvelles compositions pharmaceutiques destinees a la liberation prolongee de peptides et leur procede de preparation |
| PCT/FR1999/000667 WO1999048517A1 (fr) | 1998-03-25 | 1999-03-22 | Compositions pharmaceutiques destinees a la liberation prolongee de peptides et leur procede de preparation |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HUP0101545A1 true HUP0101545A1 (hu) | 2001-11-28 |
| HUP0101545A3 HUP0101545A3 (en) | 2001-12-28 |
| HU228903B1 HU228903B1 (en) | 2013-06-28 |
Family
ID=9524472
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0101545A HU228903B1 (en) | 1998-03-25 | 1999-03-22 | Pharmaceutical compositions for prolonged peptide release and preparation method |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6503534B1 (hu) |
| EP (1) | EP1066049B1 (hu) |
| JP (1) | JP4162381B2 (hu) |
| AR (1) | AR020062A1 (hu) |
| AT (1) | ATE241377T1 (hu) |
| AU (1) | AU756148B2 (hu) |
| CA (1) | CA2324901C (hu) |
| CZ (1) | CZ298941B6 (hu) |
| DE (1) | DE69908326T2 (hu) |
| DK (1) | DK1066049T3 (hu) |
| ES (1) | ES2200507T3 (hu) |
| FR (1) | FR2776520B1 (hu) |
| HU (1) | HU228903B1 (hu) |
| IL (2) | IL138533A0 (hu) |
| NO (1) | NO324621B1 (hu) |
| PL (1) | PL197775B1 (hu) |
| PT (1) | PT1066049E (hu) |
| RU (1) | RU2224538C2 (hu) |
| WO (1) | WO1999048517A1 (hu) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0117057D0 (en) * | 2001-07-12 | 2001-09-05 | Ferring Bv | Pharmaceutical composition |
| DK1565160T3 (da) * | 2002-09-27 | 2014-04-28 | Terna Zentaris Gmbh | Administrationsform til farmaceutisk aktive peptider med vedvarende frigivelse og en fremgangsmåde til fremstilling deraf |
| RU2255760C2 (ru) * | 2003-03-11 | 2005-07-10 | Общество с ограниченной ответственностью фирма "Фермент" | Средство, обладающее иммуномодулирующим, противомикробным, антиоксидантным и регенерирующим действием (варианты) |
| WO2004087102A2 (en) * | 2003-03-26 | 2004-10-14 | Teva Pharmaceutical Industries Ltd. | A process for preparing a pharmaceutical active ingredient with high specific surface area |
| PL1684782T3 (pl) | 2003-10-03 | 2016-03-31 | Thorn Bioscience Llc | Sposób synchronizacji owulacji dla zsynchronizowanego rozmnażania bez wykrywania rui |
| WO2005058252A2 (en) * | 2003-12-16 | 2005-06-30 | Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. | Glp-1 pharmaceutical compositions |
| US20090023644A1 (en) * | 2004-01-13 | 2009-01-22 | Southard Jeffery L | Methods of using cgrp for cardiovascular and renal indications |
| JP2007517913A (ja) * | 2004-01-13 | 2007-07-05 | バソジェニックス ファーマシューティカルズ, インコーポレイテッド | カルシトニン遺伝子関連ペプチドを投与することによって急性心筋梗塞を処置するための方法およびカルシトニン遺伝子関連ペプチドを含有する組成物 |
| WO2005067890A2 (en) * | 2004-01-13 | 2005-07-28 | Vasogenix Pharmaceuticals, Inc. | Controlled release cgrp delivery composition for cardiovascular and renal indications |
| US7772182B2 (en) * | 2004-08-05 | 2010-08-10 | Alza Corporation | Stable suspension formulations of erythropoietin receptor agonists |
| GB0428151D0 (en) | 2004-12-22 | 2005-01-26 | Novartis Ag | Organic compounds |
| GB0511269D0 (en) * | 2005-06-02 | 2005-07-13 | Creative Peptides Sweden Ab | Sustained release preparation of pro-insulin C-peptide |
| ES2638792T3 (es) * | 2005-07-28 | 2017-10-24 | Carbon Sink Inc. | Eliminación de dióxido de carbono del aire |
| GB0517627D0 (en) | 2005-08-30 | 2005-10-05 | Tyco Electronics Ltd Uk | Bus-bar and connector |
| ES2779992T3 (es) | 2005-12-20 | 2020-08-21 | Univ Duke | Métodos y composiciones para suministrar agentes activos con propiedades farmacológicas potenciadas |
| US20130172274A1 (en) | 2005-12-20 | 2013-07-04 | Duke University | Methods and compositions for delivering active agents with enhanced pharmacological properties |
| US8841255B2 (en) | 2005-12-20 | 2014-09-23 | Duke University | Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides |
| US20070219811A1 (en) * | 2006-03-16 | 2007-09-20 | Kim John S | Method for using an internet-based CRM application to create an on-line leads marketplace |
| AU2007339280B2 (en) * | 2006-12-21 | 2013-12-05 | Stryker Corporation | Sustained-release formulations comprising crystals, macromolecular gels, and particulate suspensions of biologic agents |
| JP2010523501A (ja) * | 2007-04-04 | 2010-07-15 | セラテクノロジーズ インコーポレイティド | Ghrh分子の医薬製剤 |
| TWI539959B (zh) | 2008-02-11 | 2016-07-01 | 菲瑞茵國際中心股份有限公司 | 治療轉移階段攝護腺癌的方法 |
| CA2726894A1 (en) | 2008-06-27 | 2009-12-30 | Duke University | Therapeutic agents comprising elastin-like peptides |
| EP2421545B1 (en) | 2009-04-23 | 2017-12-06 | JBS United Animal Health II LLC | Method and composition for synchronizing time of insemination |
| AU2010243273B2 (en) | 2009-05-01 | 2016-06-16 | Ferring B.V. | Composition for the treatment of prostate cancer |
| TW201043221A (en) * | 2009-05-06 | 2010-12-16 | Ferring Int Ct Sa | Kit and method for preparation of a Degarelix solution |
| US20110039787A1 (en) * | 2009-07-06 | 2011-02-17 | Ferring International Center S.A. | Compositions, kits and methods for treating benign prostate hyperplasia |
| CA2804755C (en) | 2009-08-14 | 2018-06-05 | Phasebio Pharmaceuticals, Inc. | Modified vasoactive intestinal peptides |
| JP6029472B2 (ja) * | 2010-01-13 | 2016-11-24 | イプセン ファルマ ソシエテ パール アクシオン サンプリフィエIpsen Pharma S.A.S. | ソマトスタチン類似体(アナログ)の持続的放出のための医薬組成物の製造方法 |
| LT2632934T (lt) | 2010-10-27 | 2017-01-10 | Ferring B.V. | Degarelikso ir jo tarpinių darinių gamybos būdas |
| EP2447276A1 (en) | 2010-10-27 | 2012-05-02 | Ferring B.V. | Process for the manufacture of Degarelix and its intermediates |
| JO3755B1 (ar) | 2011-01-26 | 2021-01-31 | Ferring Bv | تركيبات تستوستيرون |
| EP2717902B1 (en) | 2011-06-06 | 2018-01-24 | Phasebio Pharmaceuticals, Inc. | Use of modified vasoactive intestinal peptides in the treatment of hypertension |
| DE102011114864A1 (de) | 2011-10-05 | 2013-04-11 | Acino Ag | Verfahren zur Herstellung einer homogenen Pulvermischung und Verfahren zur Herstellung eines Implantats sowie Implantat |
| PL4512389T1 (pl) | 2012-06-01 | 2025-09-01 | Ferring B.V. | Produkt leczniczy degareliksu |
| JP2016508030A (ja) | 2012-11-28 | 2016-03-17 | ジェイビーエス ユナイテッド アニマル ヘルス セカンド エルエルシー | 未経産ブタにおける授精の時期を同期化するための方法および組成物 |
| EP2823808A1 (en) | 2013-07-09 | 2015-01-14 | Ipsen Pharma S.A.S. | Pharmaceutical composition for a sustained release of lanreotide |
| TW201605488A (zh) | 2013-10-15 | 2016-02-16 | 大塚製藥股份有限公司 | 用以預防及/或治療多囊腎病之藥物 |
| EP2910255A1 (en) * | 2014-02-19 | 2015-08-26 | MedSkin Solutions Dr. Suwelack AG | Methods for the production of biopolymers with defined average molecular weight |
| TW201625218A (zh) * | 2014-04-18 | 2016-07-16 | Jbs聯合動物保健有限責任公司 | 製造含gnrh凝膠之方法 |
| WO2015172046A1 (en) | 2014-05-08 | 2015-11-12 | Phasebio Pharmaceuticals, Inc. | Methods and compositions for treating cystic fibrosis |
| AU2016219513B2 (en) | 2015-02-09 | 2021-09-30 | Immunoforge Co., Ltd. | Methods and compositions for treating muscle disease and disorders |
| WO2020170185A1 (en) * | 2019-02-21 | 2020-08-27 | Dr. Reddy’S Laboratories Limited | Substantially pure lanreotide or its salt & process thereof |
| GR1009814B (el) * | 2019-07-29 | 2020-09-11 | Φαρματεν Α.Β.Ε.Ε. | Φαρμακευτικο σκευασμα που περιλαμβανει ενα πεπτιδιο αναλογο σωματοστατινης |
| CN110577567A (zh) * | 2019-09-03 | 2019-12-17 | 杭州诺泰澳赛诺医药技术开发有限公司 | 一种制备高比表面积活性多肽或蛋白的方法 |
| WO2023092148A1 (en) * | 2021-11-22 | 2023-05-25 | SpecGx LLC | Injectable sustained release pharmaceutical composition |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69005800T2 (de) * | 1989-05-01 | 1994-05-19 | Alkermes Inc | Verfahren zur herstellung von kleinen partikeln von biologisch aktiven molekülen. |
| JP3100005B2 (ja) * | 1992-07-28 | 2000-10-16 | 雪印乳業株式会社 | ヒト免疫不全ウィルス感染・増殖抑制剤 |
| US5595760A (en) * | 1994-09-02 | 1997-01-21 | Delab | Sustained release of peptides from pharmaceutical compositions |
-
1998
- 1998-03-25 FR FR9803667A patent/FR2776520B1/fr not_active Expired - Lifetime
-
1999
- 1999-03-22 WO PCT/FR1999/000667 patent/WO1999048517A1/fr not_active Ceased
- 1999-03-22 CA CA2324901A patent/CA2324901C/fr not_active Expired - Lifetime
- 1999-03-22 EP EP99910418A patent/EP1066049B1/fr not_active Expired - Lifetime
- 1999-03-22 ES ES99910418T patent/ES2200507T3/es not_active Expired - Lifetime
- 1999-03-22 CZ CZ20003432A patent/CZ298941B6/cs not_active IP Right Cessation
- 1999-03-22 PT PT99910418T patent/PT1066049E/pt unknown
- 1999-03-22 DK DK99910418T patent/DK1066049T3/da active
- 1999-03-22 HU HU0101545A patent/HU228903B1/hu unknown
- 1999-03-22 PL PL343005A patent/PL197775B1/pl unknown
- 1999-03-22 IL IL13853399A patent/IL138533A0/xx active IP Right Grant
- 1999-03-22 US US09/646,519 patent/US6503534B1/en not_active Expired - Lifetime
- 1999-03-22 RU RU2000126755/15A patent/RU2224538C2/ru active
- 1999-03-22 DE DE69908326T patent/DE69908326T2/de not_active Expired - Lifetime
- 1999-03-22 AU AU29384/99A patent/AU756148B2/en not_active Expired
- 1999-03-22 AT AT99910418T patent/ATE241377T1/de active
- 1999-03-22 JP JP2000537564A patent/JP4162381B2/ja not_active Expired - Lifetime
- 1999-03-23 AR ARP990101275A patent/AR020062A1/es not_active Application Discontinuation
-
2000
- 2000-09-18 IL IL138533A patent/IL138533A/en not_active IP Right Cessation
- 2000-09-22 NO NO20004741A patent/NO324621B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69908326D1 (de) | 2003-07-03 |
| RU2224538C2 (ru) | 2004-02-27 |
| HUP0101545A3 (en) | 2001-12-28 |
| EP1066049A1 (fr) | 2001-01-10 |
| AU756148B2 (en) | 2003-01-02 |
| US6503534B1 (en) | 2003-01-07 |
| DE69908326T2 (de) | 2004-03-25 |
| EP1066049B1 (fr) | 2003-05-28 |
| NO324621B1 (no) | 2007-11-26 |
| NO20004741D0 (no) | 2000-09-22 |
| CA2324901A1 (fr) | 1999-09-30 |
| NO20004741L (no) | 2000-11-22 |
| AU2938499A (en) | 1999-10-18 |
| ES2200507T3 (es) | 2004-03-01 |
| FR2776520A1 (fr) | 1999-10-01 |
| JP4162381B2 (ja) | 2008-10-08 |
| PL343005A1 (en) | 2001-07-30 |
| WO1999048517A1 (fr) | 1999-09-30 |
| AR020062A1 (es) | 2002-04-10 |
| PL197775B1 (pl) | 2008-04-30 |
| CA2324901C (fr) | 2012-01-24 |
| CZ20003432A3 (cs) | 2001-02-14 |
| IL138533A (en) | 2006-12-31 |
| FR2776520B1 (fr) | 2000-05-05 |
| ATE241377T1 (de) | 2003-06-15 |
| DK1066049T3 (da) | 2003-09-29 |
| IL138533A0 (en) | 2001-10-31 |
| HU228903B1 (en) | 2013-06-28 |
| JP2002507578A (ja) | 2002-03-12 |
| CZ298941B6 (cs) | 2008-03-19 |
| PT1066049E (pt) | 2003-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HC9A | Change of name, address |
Owner name: IPSEN PHARMA S.A.S., FR Free format text: FORMER OWNER(S): SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.), FR |