AR020062A1 - Una composicion farmaceutica solida o semisolida para la liberacion sostenida de peptidos - Google Patents
Una composicion farmaceutica solida o semisolida para la liberacion sostenida de peptidosInfo
- Publication number
- AR020062A1 AR020062A1 ARP990101275A ARP990101275A AR020062A1 AR 020062 A1 AR020062 A1 AR 020062A1 AR P990101275 A ARP990101275 A AR P990101275A AR P990101275 A ARP990101275 A AR P990101275A AR 020062 A1 AR020062 A1 AR 020062A1
- Authority
- AR
- Argentina
- Prior art keywords
- solid
- pharmaceutical composition
- peptides
- sustained release
- semisolid pharmaceutical
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 239000007787 solid Substances 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 238000013268 sustained release Methods 0.000 title 1
- 239000012730 sustained-release form Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000000499 gel Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Abstract
Una composicion farmacéutica solida o semisolida que contiene una sal de péptido soluble gelificable de alta área específica superficial. Esta composiciontambién puede comprender un excipiente y/o agua. Una vez inyectada en un paciente, la composicion se gelifica y libera la sal de péptido durante un períodoprolongado de al menos 15 días.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9803667A FR2776520B1 (fr) | 1998-03-25 | 1998-03-25 | Nouvelles compositions pharmaceutiques destinees a la liberation prolongee de peptides et leur procede de preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR020062A1 true AR020062A1 (es) | 2002-04-10 |
Family
ID=9524472
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP990101275A AR020062A1 (es) | 1998-03-25 | 1999-03-23 | Una composicion farmaceutica solida o semisolida para la liberacion sostenida de peptidos |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6503534B1 (es) |
| EP (1) | EP1066049B1 (es) |
| JP (1) | JP4162381B2 (es) |
| AR (1) | AR020062A1 (es) |
| AT (1) | ATE241377T1 (es) |
| AU (1) | AU756148B2 (es) |
| CA (1) | CA2324901C (es) |
| CZ (1) | CZ298941B6 (es) |
| DE (1) | DE69908326T2 (es) |
| DK (1) | DK1066049T3 (es) |
| ES (1) | ES2200507T3 (es) |
| FR (1) | FR2776520B1 (es) |
| HU (1) | HU228903B1 (es) |
| IL (2) | IL138533A0 (es) |
| NO (1) | NO324621B1 (es) |
| PL (1) | PL197775B1 (es) |
| PT (1) | PT1066049E (es) |
| RU (1) | RU2224538C2 (es) |
| WO (1) | WO1999048517A1 (es) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0117057D0 (en) * | 2001-07-12 | 2001-09-05 | Ferring Bv | Pharmaceutical composition |
| PL208073B1 (pl) * | 2002-09-27 | 2011-03-31 | Aeterna Zentaris Gmbh | Żelowy preparat farmaceutyczny oraz sposób jego otrzymywania i zestaw do jego wytwarzania |
| RU2255760C2 (ru) * | 2003-03-11 | 2005-07-10 | Общество с ограниченной ответственностью фирма "Фермент" | Средство, обладающее иммуномодулирующим, противомикробным, антиоксидантным и регенерирующим действием (варианты) |
| US20040247689A1 (en) * | 2003-03-26 | 2004-12-09 | Guy Samburski | Process for preparing a pharmaceutical active ingredient with high specific surface area |
| PT1684782E (pt) | 2003-10-03 | 2015-12-21 | Thorn Bioscience Llc | Processo para a sincronização da ovulação para reprodução regulada sem detecção do cio |
| EP1694278A4 (en) * | 2003-12-16 | 2009-08-12 | Ipsen Pharma | GLP-1 PHARMACEUTICAL COMPOSITIONS |
| WO2005067890A2 (en) * | 2004-01-13 | 2005-07-28 | Vasogenix Pharmaceuticals, Inc. | Controlled release cgrp delivery composition for cardiovascular and renal indications |
| EP1703916A2 (en) * | 2004-01-13 | 2006-09-27 | Vasogenix Pharmaceuticals, Inc. | Methods for treating acute myocardial infarction by calcitonin gene related peptide and compositions containing the same |
| US20090023644A1 (en) * | 2004-01-13 | 2009-01-22 | Southard Jeffery L | Methods of using cgrp for cardiovascular and renal indications |
| US7772182B2 (en) * | 2004-08-05 | 2010-08-10 | Alza Corporation | Stable suspension formulations of erythropoietin receptor agonists |
| GB0428151D0 (en) * | 2004-12-22 | 2005-01-26 | Novartis Ag | Organic compounds |
| GB0511269D0 (en) * | 2005-06-02 | 2005-07-13 | Creative Peptides Sweden Ab | Sustained release preparation of pro-insulin C-peptide |
| CN102160957A (zh) * | 2005-07-28 | 2011-08-24 | 乞力马扎罗能量公司 | 从空气中除去二氧化碳 |
| GB0517627D0 (en) | 2005-08-30 | 2005-10-05 | Tyco Electronics Ltd Uk | Bus-bar and connector |
| US8841255B2 (en) * | 2005-12-20 | 2014-09-23 | Duke University | Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides |
| EP1971355B1 (en) | 2005-12-20 | 2020-03-11 | Duke University | Methods and compositions for delivering active agents with enhanced pharmacological properties |
| US20130172274A1 (en) | 2005-12-20 | 2013-07-04 | Duke University | Methods and compositions for delivering active agents with enhanced pharmacological properties |
| US20070219811A1 (en) * | 2006-03-16 | 2007-09-20 | Kim John S | Method for using an internet-based CRM application to create an on-line leads marketplace |
| CA2671925A1 (en) * | 2006-12-21 | 2008-07-10 | Stryker Corporation | Sustained-release formulations comprising crystals, macromolecular gels, and particulate suspensions of biologic agents |
| EP2142207A4 (en) * | 2007-04-04 | 2013-01-16 | Theratechnologies Inc | PHARMACEUTICAL FORMULATIONS OF GHRH MOLECULES |
| JOP20090061B1 (ar) | 2008-02-11 | 2021-08-17 | Ferring Int Center Sa | طريقة معالجة سرطان البروستاتا بمضادات الهرمونات التناسلية GnRH |
| WO2009158704A2 (en) | 2008-06-27 | 2009-12-30 | Duke University | Therapeutic agents comprising elastin-like peptides |
| PL2421545T3 (pl) | 2009-04-23 | 2018-05-30 | Jbs United Animal Health Ii Llc | Sposób i kompozycja do synchronizacji czasu inseminacji |
| WO2010125468A1 (en) | 2009-05-01 | 2010-11-04 | Ferring International Center Sa | Composition for the treatment of prostate cancer |
| TW201043221A (en) * | 2009-05-06 | 2010-12-16 | Ferring Int Ct Sa | Kit and method for preparation of a Degarelix solution |
| US20110039787A1 (en) * | 2009-07-06 | 2011-02-17 | Ferring International Center S.A. | Compositions, kits and methods for treating benign prostate hyperplasia |
| PL3311828T3 (pl) * | 2009-08-14 | 2021-11-22 | Phasebio Pharmaceuticals, Inc. | Zmodyfikowane wazoaktywne peptydy jelitowe |
| US9352012B2 (en) * | 2010-01-13 | 2016-05-31 | Ipsen Pharma S.A.S. | Process for the preparation of pharmaceutical compositions for the sustained release of somatostatin analogs |
| EP2447276A1 (en) | 2010-10-27 | 2012-05-02 | Ferring B.V. | Process for the manufacture of Degarelix and its intermediates |
| PT2632934T (pt) | 2010-10-27 | 2017-01-06 | Ferring Bv | Processo para o fabrico de degarelix e seus intermediários |
| JO3755B1 (ar) | 2011-01-26 | 2021-01-31 | Ferring Bv | تركيبات تستوستيرون |
| WO2012170524A1 (en) | 2011-06-06 | 2012-12-13 | Phasebio Pharmaceuticals, Inc. | Use of modified vasoactive intestinal peptides in the treatment of hypertension |
| DE102011114864A1 (de) | 2011-10-05 | 2013-04-11 | Acino Ag | Verfahren zur Herstellung einer homogenen Pulvermischung und Verfahren zur Herstellung eines Implantats sowie Implantat |
| CA2874927A1 (en) | 2012-06-01 | 2013-12-05 | Gregoire Schwach | Manufacture of degarelix |
| JP2016508030A (ja) | 2012-11-28 | 2016-03-17 | ジェイビーエス ユナイテッド アニマル ヘルス セカンド エルエルシー | 未経産ブタにおける授精の時期を同期化するための方法および組成物 |
| EP2823808A1 (en) | 2013-07-09 | 2015-01-14 | Ipsen Pharma S.A.S. | Pharmaceutical composition for a sustained release of lanreotide |
| TW201605488A (zh) | 2013-10-15 | 2016-02-16 | 大塚製藥股份有限公司 | 用以預防及/或治療多囊腎病之藥物 |
| EP2910255A1 (en) * | 2014-02-19 | 2015-08-26 | MedSkin Solutions Dr. Suwelack AG | Methods for the production of biopolymers with defined average molecular weight |
| TW201625218A (zh) * | 2014-04-18 | 2016-07-16 | Jbs聯合動物保健有限責任公司 | 製造含gnrh凝膠之方法 |
| AU2015255752B2 (en) | 2014-05-08 | 2020-07-23 | Immunoforge Co., Ltd. | Methods and compositions for treating Cystic Fibrosis |
| JP6824888B2 (ja) | 2015-02-09 | 2021-02-03 | フェーズバイオ ファーマシューティカルズ,インコーポレイテッド | 筋肉の疾患および障害を治療するための方法および組成物 |
| WO2020170185A1 (en) * | 2019-02-21 | 2020-08-27 | Dr. Reddy’S Laboratories Limited | Substantially pure lanreotide or its salt & process thereof |
| GR1009814B (el) * | 2019-07-29 | 2020-09-11 | Φαρματεν Α.Β.Ε.Ε. | Φαρμακευτικο σκευασμα που περιλαμβανει ενα πεπτιδιο αναλογο σωματοστατινης |
| CN110577567A (zh) * | 2019-09-03 | 2019-12-17 | 杭州诺泰澳赛诺医药技术开发有限公司 | 一种制备高比表面积活性多肽或蛋白的方法 |
| EP4436633A4 (en) * | 2021-11-22 | 2025-10-08 | SpecGx LLC | INJECTABLE PHARMACEUTICAL COMPOSITION WITH EXTENDED RELEASE |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2030551C (en) * | 1989-05-01 | 1998-08-25 | Wayne Gombotz | Process for producing small particles of biologically active molecules |
| JP3100005B2 (ja) * | 1992-07-28 | 2000-10-16 | 雪印乳業株式会社 | ヒト免疫不全ウィルス感染・増殖抑制剤 |
| US5595760A (en) * | 1994-09-02 | 1997-01-21 | Delab | Sustained release of peptides from pharmaceutical compositions |
-
1998
- 1998-03-25 FR FR9803667A patent/FR2776520B1/fr not_active Expired - Lifetime
-
1999
- 1999-03-22 RU RU2000126755/15A patent/RU2224538C2/ru active
- 1999-03-22 JP JP2000537564A patent/JP4162381B2/ja not_active Expired - Lifetime
- 1999-03-22 AU AU29384/99A patent/AU756148B2/en not_active Expired
- 1999-03-22 CZ CZ20003432A patent/CZ298941B6/cs not_active IP Right Cessation
- 1999-03-22 PL PL343005A patent/PL197775B1/pl unknown
- 1999-03-22 DK DK99910418T patent/DK1066049T3/da active
- 1999-03-22 DE DE69908326T patent/DE69908326T2/de not_active Expired - Lifetime
- 1999-03-22 CA CA2324901A patent/CA2324901C/fr not_active Expired - Lifetime
- 1999-03-22 HU HU0101545A patent/HU228903B1/hu unknown
- 1999-03-22 EP EP99910418A patent/EP1066049B1/fr not_active Expired - Lifetime
- 1999-03-22 WO PCT/FR1999/000667 patent/WO1999048517A1/fr not_active Ceased
- 1999-03-22 ES ES99910418T patent/ES2200507T3/es not_active Expired - Lifetime
- 1999-03-22 AT AT99910418T patent/ATE241377T1/de active
- 1999-03-22 US US09/646,519 patent/US6503534B1/en not_active Expired - Lifetime
- 1999-03-22 IL IL13853399A patent/IL138533A0/xx active IP Right Grant
- 1999-03-22 PT PT99910418T patent/PT1066049E/pt unknown
- 1999-03-23 AR ARP990101275A patent/AR020062A1/es not_active Application Discontinuation
-
2000
- 2000-09-18 IL IL138533A patent/IL138533A/en not_active IP Right Cessation
- 2000-09-22 NO NO20004741A patent/NO324621B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PL197775B1 (pl) | 2008-04-30 |
| DE69908326T2 (de) | 2004-03-25 |
| WO1999048517A1 (fr) | 1999-09-30 |
| HUP0101545A1 (hu) | 2001-11-28 |
| FR2776520A1 (fr) | 1999-10-01 |
| IL138533A (en) | 2006-12-31 |
| RU2224538C2 (ru) | 2004-02-27 |
| ES2200507T3 (es) | 2004-03-01 |
| HUP0101545A3 (en) | 2001-12-28 |
| CZ298941B6 (cs) | 2008-03-19 |
| DK1066049T3 (da) | 2003-09-29 |
| CZ20003432A3 (cs) | 2001-02-14 |
| JP2002507578A (ja) | 2002-03-12 |
| DE69908326D1 (de) | 2003-07-03 |
| US6503534B1 (en) | 2003-01-07 |
| PL343005A1 (en) | 2001-07-30 |
| AU756148B2 (en) | 2003-01-02 |
| IL138533A0 (en) | 2001-10-31 |
| EP1066049A1 (fr) | 2001-01-10 |
| NO324621B1 (no) | 2007-11-26 |
| CA2324901C (fr) | 2012-01-24 |
| ATE241377T1 (de) | 2003-06-15 |
| NO20004741D0 (no) | 2000-09-22 |
| NO20004741L (no) | 2000-11-22 |
| JP4162381B2 (ja) | 2008-10-08 |
| EP1066049B1 (fr) | 2003-05-28 |
| AU2938499A (en) | 1999-10-18 |
| PT1066049E (pt) | 2003-10-31 |
| FR2776520B1 (fr) | 2000-05-05 |
| HU228903B1 (en) | 2013-06-28 |
| CA2324901A1 (fr) | 1999-09-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure | ||
| FC | Refusal |