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HK1000095B - 23(c1-c6芳基肟)ll-f28249化合物的制造程序 - Google Patents

23(c1-c6芳基肟)ll-f28249化合物的制造程序 Download PDF

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Publication number
HK1000095B
HK1000095B HK97101524.7A HK97101524A HK1000095B HK 1000095 B HK1000095 B HK 1000095B HK 97101524 A HK97101524 A HK 97101524A HK 1000095 B HK1000095 B HK 1000095B
Authority
HK
Hong Kong
Prior art keywords
nitrobenzoyl
compound
mmole
yield
dimethyl sulfoxide
Prior art date
Application number
HK97101524.7A
Other languages
German (de)
English (en)
French (fr)
Other versions
HK1000095A1 (zh
Inventor
Roy Maulding Donald
Kumar Anil
Original Assignee
Wyeth Holdings Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/405,793 external-priority patent/US4988824A/en
Application filed by Wyeth Holdings Corporation filed Critical Wyeth Holdings Corporation
Publication of HK1000095B publication Critical patent/HK1000095B/zh
Publication of HK1000095A1 publication Critical patent/HK1000095A1/zh

Links

HK97101524A 1989-09-11 1997-07-09 23(c1-c6芳基肟)ll-f28249化合物的製造程序 HK1000095A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US405793 1989-09-11
US07/405,793 US4988824A (en) 1989-09-11 1989-09-11 Process for the preparation of 23-(C1-C6 alkyloxime)-LL-F28249 compounds

Publications (2)

Publication Number Publication Date
HK1000095B true HK1000095B (zh) 1997-11-21
HK1000095A1 HK1000095A1 (zh) 1997-11-21

Family

ID=23605260

Family Applications (1)

Application Number Title Priority Date Filing Date
HK97101524A HK1000095A1 (zh) 1989-09-11 1997-07-09 23(c1-c6芳基肟)ll-f28249化合物的製造程序

Country Status (28)

Country Link
US (1) US4988824A (zh)
EP (1) EP0421081B1 (zh)
JP (1) JP2939312B2 (zh)
KR (1) KR0160977B1 (zh)
CN (1) CN1028428C (zh)
AT (1) ATE107650T1 (zh)
AU (1) AU634579B2 (zh)
BG (1) BG60620B1 (zh)
BR (1) BR9004493A (zh)
CA (1) CA2024919C (zh)
DE (1) DE69010129T2 (zh)
DK (1) DK0421081T3 (zh)
ES (1) ES2057291T3 (zh)
GE (1) GEP19981003B (zh)
HK (1) HK1000095A1 (zh)
HU (1) HU206721B (zh)
IE (1) IE66030B1 (zh)
IL (1) IL95303A (zh)
LV (1) LV10503B (zh)
MD (1) MD425C2 (zh)
NZ (1) NZ235151A (zh)
PL (1) PL165332B1 (zh)
PT (1) PT95242B (zh)
RU (1) RU2030416C1 (zh)
SI (1) SI9011711A (zh)
UA (1) UA26907C2 (zh)
YU (1) YU47520B (zh)
ZA (1) ZA907186B (zh)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU660205B2 (en) 1991-12-23 1995-06-15 Virbac, Inc Systemic control of parasites
US5439924A (en) * 1991-12-23 1995-08-08 Virbac, Inc. Systemic control of parasites
US5478951A (en) 1994-06-22 1995-12-26 American Cyanamid Company Method for the purification of 23-E isomers of 23-imino derivatives of LL-F28249 compounds
ATE199628T1 (de) 1995-02-24 2001-03-15 Novartis Erfind Verwalt Gmbh Zusammensetzung zur bekämpfung von parasiten
ES2174027T3 (es) * 1995-06-30 2002-11-01 American Cyanamid Co Composiciones estables que contienen macrolidos y macrolidos combinados con unas vacunas.
WO1999017760A2 (en) 1997-10-02 1999-04-15 Microcide Pharmaceuticals, Inc. Fungal or mammalian cell efflux pump inhibitors for enhancing susceptibility of the cell to a drug
US6762327B2 (en) * 2002-04-29 2004-07-13 Wyeth Selective oxidation process with enhanced safety
US7348417B2 (en) * 2003-08-07 2008-03-25 Wyeth Method of purifying moxidectin through crystallization
NZ548934A (en) * 2006-05-08 2007-01-26 Wyeth Corp Process for preparing moxidectin
AU2006203459B2 (en) * 2006-05-08 2010-02-25 Wyeth Intermediates and processes using them
NZ548936A (en) * 2006-06-22 2007-02-23 Wyeth Corp Selective oxidation of LL-F28249-alpha using o-iodoxybenzoic acid
PL3351546T3 (pl) 2011-12-02 2024-09-09 Boehringer Ingelheim Vetmedica Gmbh Długodziałające wstrzykiwalne postaci moksydektyny
CN104277050B (zh) * 2013-07-04 2016-05-04 北大方正集团有限公司 一种制备莫西克汀的方法
CN104017001B (zh) * 2014-06-18 2016-01-13 大连九信生物化工科技有限公司 一种化学合成莫西克汀的方法
CN104292239A (zh) * 2014-09-30 2015-01-21 大连九信生物化工科技有限公司 一种消除莫西克汀生产过程中副产物二甲基硫醚的方法
CN104628740B (zh) * 2015-02-13 2017-06-16 河北圣雪大成制药有限责任公司 一种化学合成及纯化莫西克汀的方法
CN104860961B (zh) * 2015-04-10 2017-08-04 新宇药业股份有限公司 一种制备5‑氧（对‑硝基苯甲酰）‑尼莫克汀的方法
CN106831811B (zh) * 2015-08-12 2018-10-26 内蒙古佳瑞米精细化工有限公司 一种制备高含量尼莫克汀的方法
CN114591347B (zh) * 2022-03-29 2023-03-24 河北美荷药业有限公司 莫西菌素中间体及制备方法、莫西菌素的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4201861A (en) * 1977-10-03 1980-05-06 Merck & Co., Inc. Acyl derivatives of C-076 compounds
IL78621A (en) * 1985-04-30 1991-06-30 American Cyanamid Co Mylbemycin analogs,their preparation and pesticidal compositions containing them
CA1296329C (en) * 1986-06-06 1992-02-25 Derek R. Sutherland Macrolide compounds
ES2058082T3 (es) * 1986-09-12 1994-11-01 American Cyanamid Co Derivados 23-oxo (ceto) y 23-imino de compuestos ll-f28249.
US4916154A (en) * 1986-09-12 1990-04-10 American Cyanamid Company 23-Imino derivatives of LL-F28249 compounds
US4855317A (en) * 1987-03-06 1989-08-08 Ciba-Geigy Corporation Insecticides and parasiticides
GB8721377D0 (en) * 1987-09-11 1987-10-21 Glaxo Group Ltd Chemical compounds
GB8721376D0 (en) * 1987-09-11 1987-10-21 Glaxo Group Ltd Chemical compounds
EP0341974B1 (en) * 1988-05-10 1996-01-24 American Cyanamid Company Macrolide compounds
GB8813150D0 (en) * 1988-06-03 1988-07-06 American Cyanamid Co Chemical compounds
US4900758A (en) * 1989-05-11 1990-02-13 Ici Americas Inc. Novel insecticides
EP0423445B1 (en) * 1989-09-11 1995-11-08 American Cyanamid Company 13-alkyl-23-imino and 13-halo-23-imino derivatives of LL-F28249 compounds and their use as endo- and ectoparasiticidal insecticidal, acaricidal and nematocidal agents

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