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GT200600306A - Inhibidores de glutamato agrecanasa - Google Patents

Inhibidores de glutamato agrecanasa

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Publication number
GT200600306A
GT200600306A GT200600306A GT200600306A GT200600306A GT 200600306 A GT200600306 A GT 200600306A GT 200600306 A GT200600306 A GT 200600306A GT 200600306 A GT200600306 A GT 200600306A GT 200600306 A GT200600306 A GT 200600306A
Authority
GT
Guatemala
Prior art keywords
agrecanasa
glutamate inhibitors
inhibitors
compounds
glutamate
Prior art date
Application number
GT200600306A
Other languages
English (en)
Inventor
Phaik-Eng Sum
David Brian How
Joshua James Sabatini
Jason Shaoyun Xiang
Manus Ipek
Eric Feyfant
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GT200600306A publication Critical patent/GT200600306A/es

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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • C07D213/82—Amides; Imides in position 3
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Abstract

LA PRESENTE INVENCIÓN SE REFIERE A COMPUESTOS DE LA FÓRMULA GENERAL I EN LA QUE R1,R2,R3,R4,W,M,P, SON GRUPOS FUNCIONALES DESCRITOS EN EL EXPEDIENTE. ESTOS COMPUESTOS SON INHIBIDORES DE METALOPROTEINASAS POR LO QUE SON DE UTILIDAD EN CUADROS DE OSTEOARTRITIS.
GT200600306A 2005-07-11 2006-07-11 Inhibidores de glutamato agrecanasa GT200600306A (es)

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KR20060109937A (ko) 2003-12-15 2006-10-23 니뽄 다바코 산교 가부시키가이샤 Ｎ-치환-ｎ-술포닐아미노시클로프로판 화합물 및 그의약제학적 용도

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RU2007149182A (ru) 2009-08-20
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AU2006268183B2 (en) 2012-08-09
UA94412C2 (en) 2011-05-10
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US20070043066A1 (en) 2007-02-22
KR20080031379A (ko) 2008-04-08
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AU2006268183A1 (en) 2007-01-18
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RU2436768C2 (ru) 2011-12-20
ECSP088092A (es) 2008-02-20

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