FI924160A7 - Benzanilidderivat - Google Patents

Benzanilidderivat Download PDF

Info

Publication number: FI924160A7
Authority: FI; Finland
Prior art keywords: benzane; derivatives; benzane derivatives
Prior art date: 1991-09-18

Application number

FI924160A

Other languages

English (en)

Finnish (fi)

Other versions

FI924160A0 (fi

Inventor

Alexander William Oxford

William Leonard Mitchell

John Bradshaw

John Watson Clitherow

Malcolm Carter

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-09-18

Filing date

1992-09-17

Publication date

1993-03-19

1991-09-18 Priority claimed from GB919119931A external-priority patent/GB9119931D0/en

1992-03-12 Priority claimed from GB929205338A external-priority patent/GB9205338D0/en

1992-09-17 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

1992-09-17 Publication of FI924160A0 publication Critical patent/FI924160A0/fi

1993-03-19 Publication of FI924160A7 publication Critical patent/FI924160A7/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
- C07D249/06—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
- C07D271/07—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
- C07D271/107—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles with two aryl or substituted aryl radicals attached in positions 2 and 5
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/06—1,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Psychiatry (AREA)
Endocrinology (AREA)
Pain & Pain Management (AREA)
Cardiology (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Heart & Thoracic Surgery (AREA)
Diabetes (AREA)
Gynecology & Obstetrics (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

FI924160A 1991-09-18 1992-09-17 Benzanilidderivat FI924160A7 (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB919119931A GB9119931D0 (en)	1991-09-18	1991-09-18	Chemical compounds
GB929205338A GB9205338D0 (en)	1992-03-12	1992-03-12	Chemical compounds

Publications (2)

Publication Number	Publication Date
FI924160A0 FI924160A0 (fi)	1992-09-17
FI924160A7 true FI924160A7 (fi)	1993-03-19

Family

ID=26299553

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI924160A FI924160A7 (fi)	1991-09-18	1992-09-17	Benzanilidderivat

Country Status (26)

Country	Link
US (2)	US5340810A (is)
EP (1)	EP0533268B1 (is)
JP (1)	JP3295143B2 (is)
KR (1)	KR930006011A (is)
CN (1)	CN1071919A (is)
AP (1)	AP303A (is)
AT (1)	ATE204262T1 (is)
AU (1)	AU656021B2 (is)
CA (1)	CA2078505A1 (is)
CZ (1)	CZ285492A3 (is)
DE (1)	DE69232003T2 (is)
DK (1)	DK0533268T3 (is)
ES (1)	ES2162792T3 (is)
FI (1)	FI924160A7 (is)
HU (1)	HUT65608A (is)
IL (1)	IL103198A (is)
IS (1)	IS1618B (is)
MX (1)	MX9205280A (is)
MY (1)	MY130233A (is)
NO (1)	NO923618L (is)
NZ (1)	NZ244373A (is)
OA (1)	OA10049A (is)
PL (1)	PL295960A1 (is)
PT (1)	PT533268E (is)
RU (1)	RU2077535C1 (is)
TW (1)	TW224097B (is)

Families Citing this family (84)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW240217B (is) *	1992-12-30	1995-02-11	Glaxo Group Ltd
US5834471A (en) *	1993-08-06	1998-11-10	Smithkline Beecham P.L.C.	Amide derivatives as 5HT1D receptor antagonists
US5905080A (en) *	1993-08-20	1999-05-18	Smithkline Beecham, P.L.C.	Amide and urea derivatives as 5HT1D receptor antagonists
DE69417427T2 (de) *	1993-09-03	1999-11-25	Smithkline Beecham P.L.C., Brentford	Indol- und indolin-derivate als 5ht1d rezeptor antagonisten
EP0716656A1 (en) *	1993-09-03	1996-06-19	Smithkline Beecham Plc	Amide derivatives as 5ht1d receptor antagonists
EP0724580A1 (en) *	1993-10-19	1996-08-07	Smithkline Beecham Plc	Benzanilide derivatives as 5ht-1d receptor antagonists
EP0733048A1 (en) *	1993-12-07	1996-09-25	Smithkline Beecham Plc	Heterocyclic biphenylylamides useful as 5ht1d antagonists
US20020086053A1 (en) *	1993-12-15	2002-07-04	Smithkline Beecham Plc	Formulations, tablets of paroxetine and process to prepare them
GB9326008D0 (en) *	1993-12-21	1994-02-23	Smithkline Beecham Plc	Novel compounds
WO1995017398A1 (en) *	1993-12-21	1995-06-29	Smithkline Beecham Plc	Indole, indoline and quinoline derivatives with 5ht1d (anti-depressive) activity
JPH09512804A (ja) *	1994-05-06	1997-12-22	スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー	５−ｈｔ１ｄアンタゴニストとして有用なビフェニルカルボキシアミド類
AU2565595A (en) *	1994-05-28	1995-12-21	Smithkline Beecham Plc	Amide derivatives having 5ht1d-antagonist activity
FR2722788B1 (fr) *	1994-07-20	1996-10-04	Pf Medicament	Nouvelles piperazides derivees d'aryl piperazine, leurs procedes de preparation, leur utilisation a titre de medicament et les compositions pharmaceutiques les comprenant
US5597826A (en)	1994-09-14	1997-01-28	Pfizer Inc.	Compositions containing sertraline and a 5-HT1D receptor agonist or antagonist
US5527920A (en) *	1994-11-18	1996-06-18	Singh; Inder P.	Economical manufacturing process for 1,2,3-triazoles
AP757A (en)	1994-12-22	1999-09-06	Smithkline Beecham Plc	Tetracyclic spiro piperidine compounds, a process for their preparation and their use as 5HT1D receptor antagonists in the treatment of CNS disorders.
GB9507203D0 (en) *	1995-04-07	1995-05-31	Smithkline Beecham Plc	Novel compounds
FR2740134B1 (fr) *	1995-10-18	1998-01-09	Pf Medicament	Derives d'amines cycliques d'aryl-piperazines, leur preparation et les compositions pharmaceutiques les contenant
JPH11514661A (ja) *	1995-11-08	1999-12-14	スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー	５ｍｔレセプターアンタゴニストとしてのスピロピペリジン誘導体
US5670526A (en) *	1995-12-21	1997-09-23	Otsuka Pharmaceutical Co., Ltd.	1,3,4-oxadiazoles
FR2744449B1 (fr) *	1996-02-02	1998-04-24	Pf Medicament	Nouvelles piperazines aromatiques derivees de cycloazanes substitues, ainsi que leur procede de preparation, les compositions pharmaceutiques et leur utilisation comme medicaments
FR2744450A1 (fr) *	1996-02-02	1997-08-08	Pf Medicament	Nouvelles naphtylpiperazines derivees de cycloazanes substitues, ainsi que leur procede de preparation, les compositions pharmaceutiques et leur utilisation comme medicaments
GB9605883D0 (en) *	1996-03-20	1996-05-22	Smithkline Beecham Plc	Novel compounds
GB9605945D0 (en) *	1996-03-21	1996-05-22	Smithkline Beecham Plc	Novel compounds
SE9601110D0 (sv) *	1996-03-22	1996-03-22	Astra Ab	Substituted 1,2,3,4-tetrahydronaphthalene derivatives
CN1128788C (zh)	1996-03-29	2003-11-26	辉瑞大药厂	苄基(亚苄基)－内酰胺衍生物,它们的制备以及作为5－ht1a和/或5－ht1d受体的选择性拮抗剂(激动剂)的用途
US6156783A (en) *	1996-04-30	2000-12-05	Smithkline Beecham P.L.C.	Spiroazabicyclic compounds, processes for their preparation, and their pharmaceutical use
JP3890453B2 (ja) *	1996-09-18	2007-03-07	リードケミカル株式会社	新規２，４−ジオキソピロリジンおよび２，４−ジオキソテトラヒドロフラン誘導体及び該化合物を有効成分とする医薬
FR2761064B1 (fr) *	1997-03-20	1999-06-04	Pf Medicament	Piperazines derivees d'amines cycliques, leur preparation et leur application comme medicaments
TR199902590T2 (xx) *	1997-04-18	2000-06-21	Smithkline Beecham P.L.C.	Birle�ik 5HT1A 5HT1B ve 5HT1D resept�r antagonist aktivitesi olan indol t�revleri.
SE9900190D0 (sv)	1999-01-22	1999-01-22	Astra Ab	New compounds
SE9702799D0 (sv)	1997-07-25	1997-07-25	Astra Ab	New compounds
CA2299286A1 (en) *	1997-08-09	1999-02-18	Laramie Mary Gaster	Bicyclic compounds as ligands for 5-ht1 receptors
SE9703375D0 (sv) *	1997-09-18	1997-09-18	Astra Ab	A new combination
SE9703376D0 (sv) *	1997-09-18	1997-09-18	Astra Ab	A new combination
SE9703374D0 (sv) *	1997-09-18	1997-09-18	Astra Ab	A new combination
KR20010070997A (ko) *	1998-07-20	2001-07-28	플레믹 크리스티안	비페닐 유도체
GB9826412D0 (en) *	1998-12-03	1999-01-27	Glaxo Group Ltd	Chemical compounds
PT1216239E (pt)	1999-09-25	2004-05-31	Smithkline Beecham Plc	Derivados de piperazina como antagonistas de 5-ht1b
SE9904724D0 (sv)	1999-12-22	1999-12-22	Carlsson A Research Ab	New modulators of dopamine neurotransmission I
USRE46117E1 (en)	1999-12-22	2016-08-23	Teva Pharmaceuticals International Gmbh	Modulators of dopamine neurotransmission
SE9904723D0 (sv)	1999-12-22	1999-12-22	Carlsson A Research Ab	New modulators of dopamine neurotransmission II
PE20020506A1 (es)	2000-08-22	2002-07-09	Glaxo Group Ltd	Derivados de pirazol fusionados como inhibidores de la proteina cinasa
US6514482B1 (en) *	2000-09-19	2003-02-04	Advanced Inhalation Research, Inc.	Pulmonary delivery in treating disorders of the central nervous system
US6613308B2 (en)	2000-09-19	2003-09-02	Advanced Inhalation Research, Inc.	Pulmonary delivery in treating disorders of the central nervous system
WO2002044159A2 (en) *	2000-11-29	2002-06-06	Eli Lilly And Company	1-(2-m-methanesulfonamidophenylethyl)-4-(m-trifluoromethylphenyl)piperazine and pharmaceutically acceptable salts and solvates thereof and their use in the treatment of incontinence
WO2003024448A2 (en)	2001-09-14	2003-03-27	Methylgene, Inc.	Inhibitors of histone deacetylase
GB0124931D0 (en)	2001-10-17	2001-12-05	Glaxo Group Ltd	Chemical compounds
GB0124936D0 (en) *	2001-10-17	2001-12-05	Glaxo Group Ltd	Chemical compounds
GB0124933D0 (en)	2001-10-17	2001-12-05	Glaxo Group Ltd	Chemical compounds
GB0124941D0 (en)	2001-10-17	2001-12-05	Glaxo Group Ltd	Chemical compounds
GB0124939D0 (en)	2001-10-17	2001-12-05	Glaxo Group Ltd	Chemical compounds
GB0124934D0 (en)	2001-10-17	2001-12-05	Glaxo Group Ltd	Chemical compounds
GB0124932D0 (en) *	2001-10-17	2001-12-05	Glaxo Group Ltd	Chemical compounds
GB0124938D0 (en)	2001-10-17	2001-12-05	Glaxo Group Ltd	Chemical compounds
KR101058292B1 (ko)	2002-02-12	2011-08-22	글락소스미스클라인 엘엘씨	Ｐ38 억제제로 유용한 니코틴아미드 유도체
DK1531798T3 (da)	2002-03-20	2012-08-13	Civitas Therapeutics Inc	Pulmonal frigørelse af Levodopa
US6930137B2 (en) *	2002-05-31	2005-08-16	Fina Technology, Inc.	Method of improving blown film processing performance and physical properties
GB0217757D0 (en)	2002-07-31	2002-09-11	Glaxo Group Ltd	Novel compounds
SE0203778D0 (sv) *	2002-12-09	2002-12-09	Astrazeneca Ab	A new oral immediated release dosage form
WO2004073634A2 (en) *	2003-02-20	2004-09-02	Encysive Pharmaceuticals Inc.	Phenylenediamine urotensin-ii receptor antagonists and ccr-9 antagonists
US7288538B2 (en)	2003-02-20	2007-10-30	Encysive Pharmaceuticals, Inc.	Phenylenediamine urotensin-II receptor antagonists and CCR-9 antagonists
GB0308185D0 (en)	2003-04-09	2003-05-14	Smithkline Beecham Corp	Novel compounds
GB0308201D0 (en)	2003-04-09	2003-05-14	Smithkline Beecham Corp	Novel compounds
GB0308186D0 (en)	2003-04-09	2003-05-14	Smithkline Beecham Corp	Novel compounds
GB0318814D0 (en)	2003-08-11	2003-09-10	Smithkline Beecham Corp	Novel compounds
AU2003304416A1 (en) *	2003-08-13	2005-03-07	Bf Research Institute, Inc.	Probe for disease with amyloid deposit, amyloid-staining agent, remedy and preventive for disease with amyloid deposit and diagnostic probe and staining agent for neurofibril change
DE602004028150D1 (de) *	2003-11-26	2010-08-26	Pfizer Prod Inc	Aminopyrazolderivate als gsk-3-inhibitoren
AR049478A1 (es)	2004-03-25	2006-08-09	Solvay Pharm Bv	Un procedimiento para la preparacion de 3-amino-8-(1-piperazinil)-2h-1-benzopiran-2-ona. sales e hidratos y composiciones farmaceuticas.
US20050215551A1 (en) *	2004-03-25	2005-09-29	Solvay Pharmaceuticals B.V.	1-[2H-1-benzopyran-2-one-8-yl]- piperazine derivatives for the treatment of movement disorders
KR101245075B1 (ko)	2004-06-08	2013-03-18	엔에스아베 필리알 아프 뉴로서치 스웨덴 아베 스베리게	도파민 신경전달의 모듈레이터로서 신 2기치환된페닐피페리딘/피페라진
US7851629B2 (en)	2004-06-08	2010-12-14	Nsab, Filial Af Neurosearch Sweden Ab, Sverige	Disubstituted phenylpiperidines as modulators of dopamine and serotonin neurotransmission
KR101319235B1 (ko)	2004-10-13	2013-10-16	아이백스 인터내셔널 게엠베하	4-(3-메탄설폰일페닐)-1-ｎ-프로필-피페리딘의 합성 공정
SE529246C2 (sv)	2005-10-13	2007-06-12	Neurosearch Sweden Ab	Nya disubstituerade fenyl-piperidiner som modulatorer för dopaminneurotransmission
WO2007077457A2 (en) *	2006-01-06	2007-07-12	The Royal Veterinary College	Treatment of equine laminitis with 5-ht1b/ 1d antagonists
EP1921072A1 (en) *	2006-11-10	2008-05-14	Laboratorios del Dr. Esteve S.A.	1,2,3-Triazole derivatives as cannabinoid-receptor modulators
CA2842410A1 (en) *	2010-07-23	2012-01-26	The Board Of Trustees Of The University Of Illinois	Apparatus and methods for the automated synthesis of small molecules
WO2012079232A1 (zh) *	2010-12-15	2012-06-21	Lai Hung-Cheng	用于治疗癌症的化合物及其应用
RU2538964C1 (ru)	2010-12-17	2015-01-10	Мицубиси Танабе Фарма Корпорейшн	Соединение с последовательной арициклической структурой, обладающее активностью ингибирования ацилкофермента а: диацилглицеринацилтрансферазы (dgat1)
CA2856749A1 (en)	2011-12-08	2013-06-13	IVAX International GmbH	The hydrobromide salt of pridopidine
US20130267552A1 (en)	2012-04-04	2013-10-10	IVAX International GmbH	Pharmaceutical compositions for combination therapy
EP2862856B1 (en)	2012-06-15	2018-08-01	Mitsubishi Tanabe Pharma Corporation	Imidazole and triazole compounds as dgat-1 inhibitors
WO2020183011A1 (en)	2019-03-14	2020-09-17	Institut Curie	Htr1d inhibitors and uses thereof in the treatment of cancer
US20250270200A1 (en) *	2022-04-21	2025-08-28	Nimbus Clotho, Inc.	Ctps1 inhibitors and uses thereof

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3192213A (en) *	1962-10-12	1965-06-29	Olin Mathieson	Aminoalkyl anilides
DE1668723A1 (de) *	1966-09-16	1971-04-08	Toyo Jozo Kk	Verfahren zum Herstellen von Verbindungen mit Saeureamid-Bindung
AU499714B2 (en) *	1974-10-14	1979-05-03	Chugai Seiyaku Kabushiki Kaisha	Bis(benzamido)-benzene derivatives & process for preparing thesame
US4058523A (en) *	1974-10-14	1977-11-15	Chugai Seiyaku Kabushiki Kaisha	Bis(benzamido)-benzene derivatives
US4013647A (en) *	1976-03-23	1977-03-22	American Home Products Corporation	Morpholine containing tetrazole-5-carboxamide derivatives
DE3005287A1 (de) *	1980-02-13	1981-08-20	Basf Ag, 6700 Ludwigshafen	Phenylpiperazinderivate von 1,3,4-oxadiazolylphenolen, ihre herstellung und diese enthaltende therapeutische mittel
DE3100575A1 (de) *	1981-01-10	1982-09-02	Dr. Karl Thomae Gmbh, 7950 Biberach	"neue benzoesaeuren, ihre herstellung und ihre verwendung als arzneimittel"
US4735959A (en) *	1981-01-10	1988-04-05	Dr. Karl Thomae Gmbh	Carboxylic acid amides and pharmaceutical compositions containing them
US4562201A (en) *	1982-07-26	1985-12-31	American Hospital Supply Corporation	Aminomethyl benzanilides
US4579866A (en) *	1984-05-29	1986-04-01	Usv Pharmaceutical Corp.	Phenylacetamides as anti-allergy, anti-asthma and anti-inflammatory agents
US4778796A (en) *	1985-07-19	1988-10-18	Dainippon Pharmaceutical Co., Ltd.	ω-(3-pyridyl)alkenamide derivatives and anti-allergenic pharmaceutical compositions containing same
DE3600288A1 (de) *	1986-01-08	1987-07-16	Bayer Ag	Verwendung von amiden zur verbesserung der kulturpflanzen-vertraeglichkeit von herbizid wirksamen sulfonylharnstoff-derivaten
CA1334092C (en) *	1986-07-11	1995-01-24	David John Carini	Angiotensin ii receptor blocking imidazoles
US4853398A (en) *	1987-04-13	1989-08-01	Eli Lilly And Company	Leukotriene antagonists and use thereas
US4826990A (en) *	1987-09-30	1989-05-02	American Home Products Corporation	2-aryl substituted heterocyclic compounds as antiallergic and antiinflammatory agents
ZA89135B (en) *	1988-01-11	1989-10-25	Duphar Int Res	Method of treating hematologic diseases and pharmaceutical composition to be used therefor
DE3810848A1 (de) *	1988-03-30	1989-10-19	Boehringer Ingelheim Kg	Neue 2,3,4-substituierte imidazole und 3,4,5-substituierte 1,2,4-triazole, ihre herstellung und verwendung
DE68903263T2 (de) *	1988-10-10	1993-05-19	Akzo Nv	Substituierte aromatische verbindungen mit zentraler nervensystem-wirkung.

1992
- 1992-09-14 DK DK92202806T patent/DK0533268T3/da active
- 1992-09-14 ES ES92202806T patent/ES2162792T3/es not_active Expired - Lifetime
- 1992-09-14 DE DE69232003T patent/DE69232003T2/de not_active Expired - Fee Related
- 1992-09-14 EP EP92202806A patent/EP0533268B1/en not_active Expired - Lifetime
- 1992-09-14 PT PT92202806T patent/PT533268E/pt unknown
- 1992-09-14 AT AT92202806T patent/ATE204262T1/de not_active IP Right Cessation
- 1992-09-17 PL PL29596092A patent/PL295960A1/xx unknown
- 1992-09-17 US US07/946,098 patent/US5340810A/en not_active Expired - Fee Related
- 1992-09-17 IS IS3915A patent/IS1618B/is unknown
- 1992-09-17 NZ NZ244373A patent/NZ244373A/en unknown
- 1992-09-17 CN CN92111660A patent/CN1071919A/zh active Pending
- 1992-09-17 MX MX9205280A patent/MX9205280A/es not_active IP Right Cessation
- 1992-09-17 KR KR1019920016904A patent/KR930006011A/ko not_active Ceased
- 1992-09-17 HU HU9202968A patent/HUT65608A/hu unknown
- 1992-09-17 RU SU925052871A patent/RU2077535C1/ru active
- 1992-09-17 JP JP27361992A patent/JP3295143B2/ja not_active Expired - Fee Related
- 1992-09-17 AP APAP/P/1992/000427A patent/AP303A/en active
- 1992-09-17 OA OA60277A patent/OA10049A/en unknown
- 1992-09-17 FI FI924160A patent/FI924160A7/fi not_active Application Discontinuation
- 1992-09-17 IL IL10319892A patent/IL103198A/en not_active IP Right Cessation
- 1992-09-17 CZ CS922854A patent/CZ285492A3/cs unknown
- 1992-09-17 CA CA002078505A patent/CA2078505A1/en not_active Abandoned
- 1992-09-17 NO NO92923618A patent/NO923618L/no unknown
- 1992-09-17 MY MYPI92001663A patent/MY130233A/en unknown
- 1992-09-17 AU AU24530/92A patent/AU656021B2/en not_active Ceased
- 1992-09-17 TW TW081107321A patent/TW224097B/zh active
1994
- 1994-05-03 US US08/237,297 patent/US5510350A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
NO923618D0 (no)	1992-09-17
IL103198A0 (en)	1993-02-21
NO923618L (no)	1993-03-19
IL103198A (en)	1996-06-18
AU656021B2 (en)	1995-01-19
EP0533268A1 (en)	1993-03-24
DE69232003T2 (de)	2002-04-25
KR930006011A (ko)	1993-04-20
EP0533268B1 (en)	2001-08-16
NZ244373A (en)	1995-03-28
DK0533268T3 (da)	2001-12-03
CZ285492A3 (en)	1993-04-14
MX9205280A (es)	1993-03-01
AU2453092A (en)	1993-03-25
MY130233A (en)	2007-06-29
AP9200427A0 (en)	1992-10-31
DE69232003D1 (de)	2001-09-20
ES2162792T3 (es)	2002-01-16
IS1618B (is)	1996-10-18
JP3295143B2 (ja)	2002-06-24
JPH06116251A (ja)	1994-04-26
HU9202968D0 (en)	1992-12-28
HUT65608A (en)	1994-07-28
US5510350A (en)	1996-04-23
FI924160A0 (fi)	1992-09-17
RU2077535C1 (ru)	1997-04-20
TW224097B (is)	1994-05-21
IS3915A (is)	1993-03-19
OA10049A (en)	1996-10-14
AP303A (en)	1994-01-28
US5340810A (en)	1994-08-23
CN1071919A (zh)	1993-05-12
CA2078505A1 (en)	1993-03-19
ATE204262T1 (de)	2001-09-15
PL295960A1 (en)	1993-09-06
PT533268E (pt)	2002-02-28

Publication	Publication Date	Title
DE69208877D1 (de)	1996-04-11	Chinuclidinderivate
FI924160A7 (fi)	1993-03-19	Benzanilidderivat
FI935726A7 (fi)	1993-12-20	Atsanorbornaanijohdannaisia
FI924159L (fi)	1993-03-19	Benzanilidderivat
NO922182L (no)	1992-12-04	Krystallinske oksatiolan-derivater
FI930262L (fi)	1993-01-22	Kinuklidinderivat
DE69119329D1 (de)	1996-06-13	Actinonin-Derivate
DE69125099D1 (de)	1997-04-17	Indolderivate
FI925523A0 (fi)	1992-12-04	Hydroxi- och alkoxipyridinderivat
FI925422L (fi)	1993-05-30	Indolopyrrolokarbazolderivat
FI913045A7 (fi)	1991-12-22	Heterosykleenijohdannaisia
FI921262L (fi)	1992-09-26	4-aryltiazol- eller 4-arylimidazolderivat
FI930878L (fi)	1993-04-16	A-substituerade tryptofan-dipeptoidderivat
FI923726L (fi)	1993-02-24	Sulfaterade glykosaminoglykanoidderivat
FI925763L (fi)	1993-06-21	Fungicida 2-imidazolin-5-on- och 2-imidazolin-5-tionderivat
FI922347A7 (fi)	1992-05-22	Atsaoksindolijohdannaiset
ATE144765T1 (de)	1996-11-15	Hiv-hemmende benzenacetamidderivate
FI930345L (fi)	1993-01-27	Foerfarande foer framstaellning av renat akrylamidosulfonsyramonomerderivat
DE69130255D1 (de)	1998-10-29	Oxadolderivate
FI930109L (fi)	1993-01-12	4-alkyl-imidazolderivat
FI935243L (fi)	1994-01-11	Pyridonkarboxylsyraderivat
DK0472733T3 (da)	1995-03-13	Phenantrenderivater
FI912598A7 (fi)	1991-12-01	Diokso-tetrahydrokinoliinijohdannaisia
FI912759A7 (fi)	1991-12-12	Pyridinyylipiperatsiinijohdannaisia
FI920394A7 (fi)	1992-08-02	3-kinuklidiinijohdannaiset

Legal Events

Date	Code	Title	Description
1997-04-08	FD	Application lapsed