FI880716A7 - Förfarande för framställning av terapeutiskt användbara arylpiperazinylalkylenfenylsubstituerade heterocykliska föreningar - Google Patents

Förfarande för framställning av terapeutiskt användbara arylpiperazinylalkylenfenylsubstituerade heterocykliska föreningar

Info

Publication number: FI880716A7
Authority: FI; Finland
Prior art keywords: arylpiperazinylalkylenephenyl; substituted heterocyclic; heterocyclic compounds; therapeutically useful; preparing therapeutically
Prior art date: 1987-02-17

Application number

FI880716A

Other languages

English (en)

Finnish (fi)

Other versions

FI880716A0 (sv

FI91752B (sv

FI91752C (sv

Inventor

Iii John Adams Lowe

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-02-17

Filing date

1988-02-16

Publication date

1988-08-18

1988-02-16 Application filed by Pfizer filed Critical Pfizer

1988-02-16 Publication of FI880716A0 publication Critical patent/FI880716A0/sv

1988-08-18 Publication of FI880716A7 publication Critical patent/FI880716A7/sv

1994-04-29 Publication of FI91752B publication Critical patent/FI91752B/sv

1994-08-10 Application granted granted Critical

1994-08-10 Publication of FI91752C publication Critical patent/FI91752C/sv

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/06—1,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Life Sciences & Earth Sciences (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Psychiatry (AREA)
Pharmacology & Pharmacy (AREA)
Neurology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

FI880716A 1987-02-17 1988-02-16 Förfarande för framställning av terapeutiskt användbara arylpiperazinylalkylenfenylsubstituerade heterocykliska föreningar FI91752C (sv)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US8700340		1987-02-17
US8700340		1987-02-17

Publications (4)

Publication Number	Publication Date
FI880716A0 FI880716A0 (sv)	1988-02-16
FI880716A7 true FI880716A7 (sv)	1988-08-18
FI91752B FI91752B (sv)	1994-04-29
FI91752C FI91752C (sv)	1994-08-10

Family

ID=22202287

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI880716A FI91752C (sv)	1987-02-17	1988-02-16	Förfarande för framställning av terapeutiskt användbara arylpiperazinylalkylenfenylsubstituerade heterocykliska föreningar

Country Status (30)

Country	Link
EP (1)	EP0279598B1 (sv)
JP (1)	JPH0699405B2 (sv)
KR (1)	KR900004126B1 (sv)
CN (1)	CN1015627B (sv)
AP (1)	AP88A (sv)
AR (1)	AR245125A1 (sv)
AT (1)	ATE94537T1 (sv)
AU (1)	AU583761B2 (sv)
CA (1)	CA1312080C (sv)
CS (1)	CS272783B2 (sv)
DD (1)	DD272080A5 (sv)
DE (1)	DE3884007T2 (sv)
DK (1)	DK170878B1 (sv)
EG (1)	EG18635A (sv)
ES (1)	ES2058249T3 (sv)
FI (1)	FI91752C (sv)
HU (1)	HU207731B (sv)
IE (1)	IE61258B1 (sv)
IL (1)	IL85368A0 (sv)
IN (1)	IN171858B (sv)
MA (1)	MA21183A1 (sv)
MX (1)	MX174210B (sv)
MY (1)	MY103210A (sv)
NO (1)	NO170582C (sv)
NZ (1)	NZ223530A (sv)
PL (1)	PL157118B1 (sv)
PT (1)	PT86766B (sv)
SU (1)	SU1634136A3 (sv)
YU (1)	YU46624B (sv)
ZA (1)	ZA881064B (sv)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MX173362B (es) *	1987-03-02	1994-02-23	Pfizer	Compuestos de piperazinil heterociclicos y procedimiento para su preparacion
SE8803429D0 (sv) *	1988-09-28	1988-09-28	Pharmacia Ab	Novel pyridyl- and pyrimidyl derivatives
FR2655988B1 (fr) *	1989-12-20	1994-05-20	Adir Cie	Nouveaux derives de la napht-1-yl piperazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US5162321A (en) *	1989-12-20	1992-11-10	Adir Et Compagnie	1-naphthyl piperazines useful as 5-HT1A receptor ligands
US5166156A (en) *	1989-12-20	1992-11-24	Adir Et Compagnie	Naphthyl piperazines useful as 5-HT1A receptor ligands
US5166157A (en) *	1989-12-20	1992-11-24	Adir Et Compagnie	Naphthyl piperazines useful as 5-HT1A receptor ligands
US5162324A (en) *	1989-12-20	1992-11-10	Adir Et Compagnie	Naphyl piperazines useful as 5-HT1A receptor ligands
JP3057763B2 (ja) *	1995-06-06	2000-07-04	ヘキスト・マリオン・ルセル・インコーポレイテツド	抗精神病薬としてのベンゾイソオキサゾール及びインダゾール誘導体
GB9517381D0 (en) *	1995-08-24	1995-10-25	Pharmacia Spa	Aryl and heteroaryl piperazine derivatives
PL327582A1 (en)	1995-12-29	1998-12-21	Boehringer Ingelheim Pharma	Derivatives of phenylthiazole exhibiting antiviral properties against herpes virues
US6288091B1 (en)	1995-12-29	2001-09-11	Boehringer Ingelheim Ltd.	Antiherpes virus compounds and methods for their preparation and use
WO1999001420A1 (en) *	1997-07-03	1999-01-14	Taito Co., Ltd.	Process for the preparation of 2-aminomalonic acid derivatives and intermediates used in the process
HK1215170A1 (zh)	2012-11-14	2016-08-19	The Johns Hopkins University	治療精神分裂症的方法和組合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2927924A (en) *	1958-04-03	1960-03-08	Lilly Co Eli	Novel phenethyl-substituted piperazines
GB948766A (en) *	1959-10-20	1964-02-05	May & Baker Ltd	Trifluoromethylphenylpiperazine derivatives
DE1695410A1 (de) *	1967-04-20	1971-04-08	Merck Patent Gmbh	Verfahren zur Herstellung von 1-(Thiazolyl-5-alkyl)-4-(pyridyl-2)-piperazinen
JPS5910675B2 (ja) *	1976-03-22	1984-03-10	ウェルファイド株式会社	アラルキルアミン誘導体
US4411901A (en) *	1981-12-23	1983-10-25	Mead Johnson & Company	Benzisothiazole and benzisoxazole piperazine derivatives
US4619930A (en) *	1985-01-16	1986-10-28	Bristol-Myers Company	Antipsychotic cyclic imide derivatives of 2-(4-butylpiperazin-1-yl)pyridines, compositions and use
JPH075579B2 (ja) *	1986-09-01	1995-01-25	吉富製薬株式会社	アミノチアゾ−ル化合物

1987
- 1987-02-17 MX MX010428A patent/MX174210B/es unknown
1988
- 1988-01-27 IN IN64/DEL/88A patent/IN171858B/en unknown
- 1988-02-09 IL IL85368A patent/IL85368A0/xx not_active IP Right Cessation
- 1988-02-12 DE DE88301171T patent/DE3884007T2/de not_active Expired - Fee Related
- 1988-02-12 ES ES88301171T patent/ES2058249T3/es not_active Expired - Lifetime
- 1988-02-12 EP EP88301171A patent/EP0279598B1/en not_active Expired - Lifetime
- 1988-02-12 AT AT88301171T patent/ATE94537T1/de not_active IP Right Cessation
- 1988-02-13 KR KR1019880001454A patent/KR900004126B1/ko not_active Expired
- 1988-02-15 PT PT86766A patent/PT86766B/pt not_active IP Right Cessation
- 1988-02-15 CA CA000558900A patent/CA1312080C/en not_active Expired - Lifetime
- 1988-02-15 CN CN88100986A patent/CN1015627B/zh not_active Expired
- 1988-02-15 JP JP63032593A patent/JPH0699405B2/ja not_active Expired - Fee Related
- 1988-02-15 MA MA21420A patent/MA21183A1/fr unknown
- 1988-02-15 PL PL1988270653A patent/PL157118B1/pl unknown
- 1988-02-16 DD DD88312959A patent/DD272080A5/de not_active IP Right Cessation
- 1988-02-16 AR AR88310090A patent/AR245125A1/es active
- 1988-02-16 AU AU11740/88A patent/AU583761B2/en not_active Ceased
- 1988-02-16 AP APAP/P/1988/000082A patent/AP88A/en active
- 1988-02-16 ZA ZA881064A patent/ZA881064B/xx unknown
- 1988-02-16 DK DK078888A patent/DK170878B1/da not_active IP Right Cessation
- 1988-02-16 IE IE42088A patent/IE61258B1/en not_active IP Right Cessation
- 1988-02-16 NO NO880667A patent/NO170582C/no not_active IP Right Cessation
- 1988-02-16 YU YU30388A patent/YU46624B/sh unknown
- 1988-02-16 FI FI880716A patent/FI91752C/sv active IP Right Grant
- 1988-02-16 HU HU88748A patent/HU207731B/hu unknown
- 1988-02-16 SU SU4355194A patent/SU1634136A3/ru active
- 1988-02-16 MY MYPI88000161A patent/MY103210A/en unknown
- 1988-02-16 NZ NZ223530A patent/NZ223530A/xx unknown
- 1988-02-16 CS CS96488A patent/CS272783B2/cs not_active IP Right Cessation
- 1988-02-17 EG EG9388A patent/EG18635A/xx active

Also Published As

Publication number	Publication date
AU1174088A (en)	1988-08-18
PL157118B1 (pl)	1992-04-30
PT86766B (pt)	1992-05-29
NO880667D0 (no)	1988-02-16
IL85368A0 (en)	1988-07-31
CN88100986A (zh)	1988-09-21
ZA881064B (en)	1989-09-27
MX10428A (es)	1993-09-01
AP88A (en)	1990-06-06
DK78888D0 (da)	1988-02-16
AP8800082A0 (en)	1988-02-01
NZ223530A (en)	1990-07-26
CS272783B2 (en)	1991-02-12
FI880716A0 (sv)	1988-02-16
YU46624B (sh)	1994-01-20
KR900004126B1 (ko)	1990-06-16
IN171858B (sv)	1993-01-23
DE3884007D1 (de)	1993-10-21
ES2058249T3 (es)	1994-11-01
SU1634136A3 (ru)	1991-03-07
NO170582C (no)	1992-11-04
EG18635A (en)	1994-04-30
NO170582B (no)	1992-07-27
KR880009964A (ko)	1988-10-06
CN1015627B (zh)	1992-02-26
JPH0699405B2 (ja)	1994-12-07
HUT50334A (en)	1990-01-29
PT86766A (pt)	1988-03-01
MX174210B (es)	1994-04-28
YU30388A (en)	1989-10-31
JPS63216875A (ja)	1988-09-09
FI91752B (sv)	1994-04-29
EP0279598B1 (en)	1993-09-15
DD272080A5 (de)	1989-09-27
AU583761B2 (en)	1989-05-04
MA21183A1 (fr)	1988-10-01
CA1312080C (en)	1992-12-29
IE880420L (en)	1988-08-17
ATE94537T1 (de)	1993-10-15
DE3884007T2 (de)	1994-01-20
MY103210A (en)	1993-05-29
PL270653A1 (en)	1988-12-08
HU207731B (en)	1993-05-28
AR245125A1 (es)	1993-12-30
FI91752C (sv)	1994-08-10
EP0279598A2 (en)	1988-08-24
DK170878B1 (da)	1996-02-26
NO880667L (no)	1988-08-18
EP0279598A3 (en)	1989-07-26
DK78888A (da)	1988-08-18
IE61258B1 (en)	1994-10-19
CS96488A2 (en)	1990-04-11

Publication	Publication Date	Title
FI883064A7 (sv)	1988-12-25	Förfarande för framställning av terapeutiskt användbara heterocykliska föreningar
FI893433A7 (sv)	1990-01-15	Förfarande för framställning av terapeutiskt användbara heterocykliska föreningar
FI880941A7 (sv)	1988-09-03	Förfarande för framställning av terapeutiskt användbara piperazinyl-heterocykliska föreningar
FI885917A7 (sv)	1989-06-25	Förfarande för framställning av heterocykliska föreningar
FI885409A7 (sv)	1989-05-24	Förfarande för framställning av nya terapeutiskt användbara pyridazinaminderivat
FI905941A7 (sv)	1991-06-07	Förfarande för framställning av terapeutiskt användbara heterocykliska 2-acylaminotiazolderivat
FI883249A7 (sv)	1989-01-11	Förfarande för framställning av terapeutiskt användbara 3-desmetylmevalonsyraderivat
FI881180L (sv)	1988-09-14	Förfarande för framställning av terapeutiskt användbara tetrahydronaftalenderivat
FI883050L (sv)	1988-12-25	Förfarande för framställning av terapeutiskt aktiva pyranoindolizinokinolinderivat
PT88596A (pt)	1988-10-01	Process for preparing 2-anilinopyrimidine derivatives useful aspesticidas
FI854797A7 (sv)	1986-06-22	Förfarande för framställning av terapeutiskt användbara oxetanoner
FI872785A7 (sv)	1987-12-24	Förfarande för framställning av terapeutiskt användbara triazolföreningar
FI880816A7 (sv)	1988-09-24	Förfarande för framställning av nya terapeutiskt användbara kinoxalinderivat
BG49939A3 (bg)	1992-03-16	Метод за получаване на 2-анилино-пиримидинови производни
FI893405L (sv)	1989-07-13	Förfarande för framställning av kinolonföreningar
FI882030A7 (sv)	1988-10-31	Förfarande för framställning av terapeutiskt aktiva polycykliska heterocykliska föreningar
FI884627A7 (sv)	1989-04-10	Förfarande för framställning av nya terapeutiskt användbara dideoxicytidinderivat
FI880869A7 (sv)	1988-08-26	Förfarande för framställning av terapeutiskt aktiva tetrazolderivat
FI884553A7 (sv)	1989-04-06	Analogiförfarande för framställning av terapeutiskt användbara 9-aminotetrahydroakridinderivat
FI883889A7 (sv)	1989-02-27	Förfarande för framställning av nya terapeutiskt användbara aristeromycin/adenosinderivat
FI883672A7 (sv)	1989-02-08	Förfarande för framställning av terapeutiskt användbara aminoalkoxifenylderivat
FI880467A7 (sv)	1988-08-05	Förfarande för framställning av terapeutiskt användbara substituerade 3,4-dihydro-2H-benzopyraner
FI884910A7 (sv)	1989-04-28	Förfarande för framställning av terapeutiskt användbart bensopyranderivat
FI880716A7 (sv)	1988-08-18	Förfarande för framställning av terapeutiskt användbara arylpiperazinylalkylenfenylsubstituerade heterocykliska föreningar
FI881525A7 (sv)	1988-10-02	Förfarande för framställning av nya terapeutiskt användbara N-arylpiperazinacetamidderivat

Legal Events

Date	Code	Title	Description
1994-04-05	BB	Publication of examined application
2004-08-31	FG	Patent granted	Owner name: PFIZER INC.