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FI20011622A0 - Förfarande för framställning av citalopram - Google Patents

Förfarande för framställning av citalopram

Info

Publication number
FI20011622A0
FI20011622A0 FI20011622A FI20011622A FI20011622A0 FI 20011622 A0 FI20011622 A0 FI 20011622A0 FI 20011622 A FI20011622 A FI 20011622A FI 20011622 A FI20011622 A FI 20011622A FI 20011622 A0 FI20011622 A0 FI 20011622A0
Authority
FI
Finland
Prior art keywords
citalopram
preparation
Prior art date
Application number
FI20011622A
Other languages
English (en)
Finnish (fi)
Other versions
FI20011622L (sv
FI20011622A7 (sv
Inventor
Hans Petersen
Haleh Ahmadian
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of FI20011622A0 publication Critical patent/FI20011622A0/sv
Publication of FI20011622L publication Critical patent/FI20011622L/sv
Publication of FI20011622A7 publication Critical patent/FI20011622A7/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Furan Compounds (AREA)
  • Steroid Compounds (AREA)
FI20011622A 2000-08-18 2001-08-09 Förfarande för framställning av citalopram FI20011622A7 (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200001231 2000-08-18

Publications (3)

Publication Number Publication Date
FI20011622A0 true FI20011622A0 (sv) 2001-08-09
FI20011622L FI20011622L (sv) 2002-02-19
FI20011622A7 FI20011622A7 (sv) 2002-02-19

Family

ID=8159660

Family Applications (2)

Application Number Title Priority Date Filing Date
FI20011622A FI20011622A7 (sv) 2000-08-18 2001-08-09 Förfarande för framställning av citalopram
FI20011621A FI20011621L (sv) 2000-08-18 2001-08-09 Förfarande för framställning av citalopram

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI20011621A FI20011621L (sv) 2000-08-18 2001-08-09 Förfarande för framställning av citalopram

Country Status (41)

Country Link
US (2) US6426422B1 (sv)
EP (2) EP1309581B1 (sv)
JP (2) JP2004506730A (sv)
KR (2) KR100887206B1 (sv)
CN (3) CN1239490C (sv)
AR (3) AR029597A1 (sv)
AT (4) ATE281448T1 (sv)
AU (6) AU7960901A (sv)
BE (2) BE1013443A6 (sv)
BG (2) BG65964B1 (sv)
CA (2) CA2354877C (sv)
CH (2) CH691969A5 (sv)
CL (2) CL2008002412A1 (sv)
CZ (2) CZ295863B6 (sv)
DE (4) DE60106933T2 (sv)
DK (4) DK1309582T3 (sv)
EA (2) EA005811B1 (sv)
ES (4) ES2230347T3 (sv)
FI (2) FI20011622A7 (sv)
FR (2) FR2813078B1 (sv)
GB (2) GB2362647B (sv)
GR (1) GR1004074B (sv)
HK (2) HK1044538B (sv)
HR (2) HRP20030064A2 (sv)
HU (2) HUP0103291A3 (sv)
IE (2) IES20010761A2 (sv)
IL (2) IL144817A0 (sv)
IS (2) IS2120B (sv)
ME (2) MEP2208A (sv)
MX (2) MXPA03001329A (sv)
NL (2) NL1018775C1 (sv)
NO (2) NO326570B1 (sv)
NZ (2) NZ523877A (sv)
PL (2) PL359969A1 (sv)
PT (2) PT1309581E (sv)
RS (2) RS50258B (sv)
SI (2) SI1309582T1 (sv)
SK (2) SK287008B6 (sv)
UA (2) UA72340C2 (sv)
WO (2) WO2002016341A1 (sv)
ZA (1) ZA200106683B (sv)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
KR100604156B1 (ko) * 1999-04-14 2006-07-25 하. 룬트벡 아크티에 셀스카브 시탈로프람의 제조방법
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
HK1043129B (zh) 1999-10-25 2004-10-21 H‧隆德贝克有限公司 西酞普蘭的製備方法
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
CN1398263A (zh) 1999-12-28 2003-02-19 H·隆德贝克有限公司 制备西酞普兰的方法
HK1052512B (zh) 1999-12-30 2006-03-03 H. 隆德贝克有限公司 西酞普兰的制备方法
PL197821B1 (pl) * 2000-01-14 2008-04-30 Lundbeck & Co As H Sposób wytwarzania 5-cyjanoftalidu
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
NZ521204A (en) * 2000-03-13 2004-03-26 H Stepwise alkylation of 5-substituted 1-(4-fluorophenyl)- 1,3-dihydroisobenzofurans for preparing citalopram, an anti depressant
TR200202166T2 (tr) 2000-03-13 2002-12-23 H. Lndbeck A/S Sitalopramın preparasyon metodu
NL1017500C1 (nl) 2000-03-13 2001-04-26 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
PT1265882E (pt) 2000-03-14 2004-06-30 Lundbeck & Co As H Metodo para preparacao de citalopram; composto e citalopram
HUP0300134A2 (en) * 2000-03-16 2003-05-28 Lundbeck & Co As H Method for the preparation of 5-cyano-1-(4-fluorophenyl)-1,3-dihydroisobenzofurans
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
IL144817A0 (en) 2000-08-18 2002-06-30 Lundbeck & Co As H Method for the preparation of citalopram
IL147226A (en) 2000-12-22 2006-04-10 Lundbeck & Co As H Process for the preparation of pure citalopram
AU2003222435A1 (en) * 2002-01-07 2003-07-24 Sun Pharmaceutical Industries Limited Process for the preparation of 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)- 1,3-dihydro-5-isobenzofuran carbonitrile
TWI306846B (en) * 2002-08-12 2009-03-01 Lundbeck & Co As H Method for the separation of intermediates which may be used for the preparation of escitalopram
AU2003223105A1 (en) * 2003-03-24 2004-10-18 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
US20050143350A1 (en) * 2003-11-19 2005-06-30 Seed John C. Combination drug therapy to treat obesity
CN100569765C (zh) 2003-12-19 2009-12-16 杭州民生药业集团有限公司 西酞普兰中间体晶体碱
WO2009111031A2 (en) * 2008-03-04 2009-09-11 Intra-Cellular Therapies, Inc. Methods of treating vasomotor symptoms
US20100087664A1 (en) * 2008-10-07 2010-04-08 Ravindra Vedantham Preparation of citalopram and salts thereof
JP6222973B2 (ja) * 2013-04-19 2017-11-01 日本テルペン化学株式会社 ジベンジルトリチオカーボネート誘導体
CN103936702A (zh) * 2014-05-07 2014-07-23 成都诺维尔生物医药有限公司 艾司西酞普兰杂质j的合成方法
US9809524B1 (en) * 2014-10-14 2017-11-07 Syngenta Participations Process for the preparation of 1-(3,5-dichloro-4-fluoro-phenyl)-2,2,2-trifluoro-ethanone
CN118724848A (zh) * 2023-03-29 2024-10-01 中国石油化工股份有限公司 一种制备2,5-呋喃二甲腈的方法

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143703A (sv) 1965-03-18
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
DE3926765A1 (de) 1989-08-12 1991-02-14 Hoechst Ag Verfahren zur verminderung von primaerem und sekundaerem amin in einem tertiaeren amin
DK213290D0 (da) 1990-09-06 1990-09-06 Lundbeck & Co As H Treatment of cerebrovascular disorders
US5296507A (en) 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
DE19626659A1 (de) 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
ZA9711376B (en) 1996-12-20 1998-07-21 Lundbeck & Co As H Indole or dihydroindole derivatives
SK283309B6 (sk) * 1997-07-08 2003-05-02 H. Lundbeck A/S Spôsob výroby citalopramu a medziprodukty
UA62985C2 (en) 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
ES2149734T3 (es) 1997-11-11 2003-02-16 Lundbeck & Co As H Metodo para la preparacion de citalopram.
WO2000023431A1 (en) 1998-10-20 2000-04-27 H. Lundbeck A/S Method for the preparation of citalopram
EP1140886B1 (en) 1998-12-23 2003-04-02 H. Lundbeck A/S Method for the preparation of 5-cyanophthalide
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
KR100604156B1 (ko) 1999-04-14 2006-07-25 하. 룬트벡 아크티에 셀스카브 시탈로프람의 제조방법
ITMI991579A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
EP1228056B1 (en) 1999-10-25 2004-09-22 H. Lundbeck A/S Method for the preparation of citalopram
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
IES20010143A2 (en) 2000-02-24 2001-07-25 Lundbeck & Co As H Method for the preparation of citalopram
NL1017415C1 (nl) 2000-02-24 2001-05-18 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
GB0005477D0 (en) * 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
IL144817A0 (en) 2000-08-18 2002-06-30 Lundbeck & Co As H Method for the preparation of citalopram
IL147226A (en) 2000-12-22 2006-04-10 Lundbeck & Co As H Process for the preparation of pure citalopram
SK284418B6 (sk) 2000-12-28 2005-04-01 H. Lundbeck A/S Spôsob výroby citalopramu

Also Published As

Publication number Publication date
DE60106932T2 (de) 2005-11-03
SI1309581T1 (en) 2005-04-30
IS2121B (is) 2006-06-15
AT4946U1 (de) 2002-01-25
ES2170735B2 (es) 2003-09-16
FI20011621A0 (sv) 2001-08-09
JP2004506730A (ja) 2004-03-04
ATE281448T1 (de) 2004-11-15
CL2008002412A1 (es) 2009-01-02
CZ294746B6 (cs) 2005-03-16
CN1159307C (zh) 2004-07-28
GB0119733D0 (en) 2001-10-03
NL1018776C1 (nl) 2001-10-24
NZ523877A (en) 2004-08-27
KR20030022378A (ko) 2003-03-15
DE60106933D1 (de) 2004-12-09
DK1309581T3 (da) 2005-03-14
GR1004074B (el) 2002-11-26
FR2813078B1 (fr) 2004-04-02
ES2170734B2 (es) 2003-09-16
BG107584A (bg) 2004-01-30
BE1013444A6 (fr) 2002-01-15
HRP20030064A2 (en) 2005-02-28
HRP20030065A2 (en) 2005-02-28
KR100887206B1 (ko) 2009-03-06
HK1068069A1 (en) 2005-04-22
IES20010761A2 (en) 2002-02-20
SK3202003A3 (en) 2003-08-05
FI20011622L (sv) 2002-02-19
EP1309581A1 (en) 2003-05-14
NL1018775C1 (nl) 2001-10-24
CH691968A5 (de) 2001-12-14
AU2001279609B2 (en) 2007-09-06
MXPA03000913A (es) 2003-06-24
RS50287B (sr) 2009-09-08
NZ523853A (en) 2004-07-30
FR2813078A1 (fr) 2002-02-22
EP1309582A1 (en) 2003-05-14
IL144816A0 (en) 2002-06-30
BG107583A (bg) 2004-01-30
EA200300277A1 (ru) 2003-08-28
GB2362647B (en) 2002-09-18
DE60106933T2 (de) 2005-12-01
BG65964B1 (bg) 2010-07-30
UA71676C2 (en) 2004-12-15
AU2001100278A4 (en) 2001-09-13
BE1013443A6 (fr) 2002-01-15
AR029598A1 (es) 2003-07-10
US20020025982A1 (en) 2002-02-28
NO20013943D0 (no) 2001-08-14
EA200300279A1 (ru) 2003-08-28
AU7960901A (en) 2002-03-04
GB0119734D0 (en) 2001-10-03
NO20013942D0 (no) 2001-08-14
DK200101216A (da) 2002-02-19
HUP0103295A2 (hu) 2002-05-29
NO20013942L (no) 2002-02-19
ZA200106683B (en) 2002-08-05
AU2001100271B4 (en) 2001-11-29
HK1047086A1 (en) 2003-02-07
BG65965B1 (bg) 2010-07-30
SI1309582T1 (en) 2005-06-30
EP1309582B1 (en) 2004-11-03
IL144816A (en) 2005-09-25
IES20010760A2 (en) 2002-02-20
DE60106932D1 (de) 2004-12-09
AR029597A1 (es) 2003-07-10
IL144817A0 (en) 2002-06-30
GB2365865A (en) 2002-02-27
FI20011621A7 (sv) 2002-02-19
FR2813077A1 (fr) 2002-02-22
ES2170734A1 (es) 2002-08-01
CA2354877A1 (en) 2002-02-18
CZ295863B6 (cs) 2005-11-16
CN1339436A (zh) 2002-03-13
NO326772B1 (no) 2009-02-16
CN1222517C (zh) 2005-10-12
NO326570B1 (no) 2009-01-12
PT1309582E (pt) 2005-03-31
AU2001100278B4 (en) 2001-11-29
WO2002016341A1 (en) 2002-02-28
PT1309581E (pt) 2005-03-31
CH691969A5 (de) 2001-12-14
HK1047086B (zh) 2005-04-22
IS6048A (is) 2001-10-19
JP2004506729A (ja) 2004-03-04
AU2001100271A4 (en) 2001-09-13
MEP2308A (xx) 2010-02-10
AR066694A2 (es) 2009-09-09
ATE281447T1 (de) 2004-11-15
DE10140029A1 (de) 2002-05-02
NO20013943L (no) 2002-02-19
RS50258B (sr) 2009-07-15
AU2001279608B2 (en) 2006-10-05
HK1044538A1 (en) 2002-10-25
GB2362647A (en) 2001-11-28
EP1309581B1 (en) 2004-11-03
US6509483B2 (en) 2003-01-21
ES2230347T3 (es) 2005-05-01
CA2354880C (en) 2003-06-03
FI20011621L (sv) 2002-02-19
AU7960801A (en) 2002-03-04
CN1515564A (zh) 2004-07-28
CA2354880A1 (en) 2002-01-22
HK1044538B (zh) 2006-07-07
SK3222003A3 (en) 2003-08-05
DE10140028A1 (de) 2002-04-18
EA005946B1 (ru) 2005-08-25
IS6047A (is) 2001-10-20
IS2120B (is) 2006-06-15
HUP0103295A3 (en) 2005-01-28
YU11503A (sh) 2006-05-25
FI20011622A7 (sv) 2002-02-19
CL2008002673A1 (es) 2009-01-02
UA72340C2 (uk) 2005-02-15
KR100887207B1 (ko) 2009-03-06
MEP2208A (xx) 2010-02-10
HUP0103291A2 (hu) 2002-05-29
FR2813077B1 (fr) 2004-08-20
YU6903A (sh) 2006-05-25
CN1239490C (zh) 2006-02-01
CZ20012958A3 (cs) 2002-04-17
WO2002016342A1 (en) 2002-02-28
PL359825A1 (pl) 2004-09-06
AT5026U1 (de) 2002-02-25
DK1309582T3 (da) 2005-03-14
DK200101219A (da) 2002-02-19
SK287008B6 (sk) 2009-09-07
GB2365865B (en) 2002-07-17
US6426422B1 (en) 2002-07-30
HU0103291D0 (en) 2001-10-28
CZ20012959A3 (cs) 2002-04-17
CN1339435A (zh) 2002-03-13
EA005811B1 (ru) 2005-06-30
KR20030022385A (ko) 2003-03-15
ES2228920T3 (es) 2005-04-16
SK287236B6 (sk) 2010-04-07
US20020026062A1 (en) 2002-02-28
MXPA03001329A (es) 2003-06-06
ES2170735A1 (es) 2002-08-01
GR20010100398A (el) 2002-05-24
PL359969A1 (en) 2004-09-06
CA2354877C (en) 2006-05-02
HUP0103291A3 (en) 2003-02-28

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