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ES8706653A1 - Un procedimiento para la preparacion depropionilamilidas - Google Patents

Un procedimiento para la preparacion depropionilamilidas

Info

Publication number
ES8706653A1
ES8706653A1 ES554933A ES554933A ES8706653A1 ES 8706653 A1 ES8706653 A1 ES 8706653A1 ES 554933 A ES554933 A ES 554933A ES 554933 A ES554933 A ES 554933A ES 8706653 A1 ES8706653 A1 ES 8706653A1
Authority
ES
Spain
Prior art keywords
propionylanilides
pharmacologically active
morbid
cold
useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES554933A
Other languages
English (en)
Other versions
ES554933A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Erregierre Industria Chimica SpA
Original Assignee
Erregierre Industria Chimica SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erregierre Industria Chimica SpA filed Critical Erregierre Industria Chimica SpA
Publication of ES8706653A1 publication Critical patent/ES8706653A1/es
Publication of ES554933A0 publication Critical patent/ES554933A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

METODO DE OBTENER PROPIONILANILIDAS. CONSISTE EN HACER REACCIONAR UN DERIVADO REACTIVO DE LOS ACIDOS DE FORMULA (II) CON UN DERIVADO DE ANILIDA DE FORMULA (III), EN UN MEDIO REACCIONAL, CONSTITUIDO POR UN DISOLVENTE ORGANICO INERTE, TAL COMO TETRAHIDROCLORURO DE CARBONO O DICLOROETANO, EN PRESENCIA DE AMINAS TERCIARIAS ALIFATICAS, AROMATICAS Y/O HETEROCICLICAS TALES COMO POR EJEMPLO, TRIMETILAMINA Y PIRIDINA, Y A TEMPERATURA ENTRE 5 Y 30GC PARA OBTENER PROPIONILANILIDAS DE FORMULA (I), DONDE R ES UN GRUPO 4-ISOBUTILFENIL, 3-BENZOIFENILO, 6-METOXI-2-NAFTILO Y 2-FLUORO-4-DIFENILO. TIENEN APLICACIONES FARMACEUTICAS POR SU ACTIVIDAD ANTIINFLAMATORIA, ANALGESICA Y ANTIPIRETICA. *FORMULA*
ES554933A 1985-05-15 1986-05-14 Un procedimiento para la preparacion depropionilamilidas Expired ES8706653A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20726/85A IT1191617B (it) 1985-05-15 1985-05-15 Propionilanilidi farmacologicamente attive

Publications (2)

Publication Number Publication Date
ES8706653A1 true ES8706653A1 (es) 1987-07-01
ES554933A0 ES554933A0 (es) 1987-07-01

Family

ID=11171140

Family Applications (1)

Application Number Title Priority Date Filing Date
ES554933A Expired ES8706653A1 (es) 1985-05-15 1986-05-14 Un procedimiento para la preparacion depropionilamilidas

Country Status (11)

Country Link
US (1) US4639449A (es)
EP (1) EP0202482B1 (es)
JP (1) JPS61263966A (es)
AT (1) ATE56445T1 (es)
CA (1) CA1260470A (es)
DE (1) DE3674060D1 (es)
DK (1) DK222886A (es)
ES (1) ES8706653A1 (es)
IT (1) IT1191617B (es)
NO (1) NO861917L (es)
PT (1) PT82535B (es)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1518375A1 (de) * 1965-06-08 1969-08-14 Thomae Gmbh Dr K Verfahren zur Herstellung von neuen 2-Amino-halogenbenzylaminen
US3769408A (en) * 1965-06-08 1973-10-30 Boehringer Sohn Ingelheim Pharmaceutical compositions containing a halo-substituted 2-amino-benzylamine-morpholide or a salt thereof

Also Published As

Publication number Publication date
IT1191617B (it) 1988-03-23
DK222886D0 (da) 1986-05-14
EP0202482B1 (en) 1990-09-12
PT82535A (en) 1986-06-01
IT8520726A0 (it) 1985-05-15
PT82535B (en) 1987-09-23
ATE56445T1 (de) 1990-09-15
CA1260470A (en) 1989-09-26
JPS61263966A (ja) 1986-11-21
DK222886A (da) 1986-11-16
EP0202482A1 (en) 1986-11-26
US4639449A (en) 1987-01-27
NO861917L (no) 1986-11-17
DE3674060D1 (de) 1990-10-18
ES554933A0 (es) 1987-07-01

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