ES8604249A1 - Un procedimiento para preparar pseudomonato de calcio cris- talino o un hidrato del mismo - Google Patents
Un procedimiento para preparar pseudomonato de calcio cris- talino o un hidrato del mismoInfo
- Publication number
- ES8604249A1 ES8604249A1 ES544329A ES544329A ES8604249A1 ES 8604249 A1 ES8604249 A1 ES 8604249A1 ES 544329 A ES544329 A ES 544329A ES 544329 A ES544329 A ES 544329A ES 8604249 A1 ES8604249 A1 ES 8604249A1
- Authority
- ES
- Spain
- Prior art keywords
- crystalline calcium
- calcium pseudomonate
- pseudomonate
- disclosed
- crystalline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- DDHVILIIHBIMQU-YJGQQKNPSA-L mupirocin calcium hydrate Chemical compound O.O.[Ca+2].C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@@H]1[C@@H](O)[C@@H](O)[C@H](C\C(C)=C\C(=O)OCCCCCCCCC([O-])=O)OC1.C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@@H]1[C@@H](O)[C@@H](O)[C@H](C\C(C)=C\C(=O)OCCCCCCCCC([O-])=O)OC1 DDHVILIIHBIMQU-YJGQQKNPSA-L 0.000 title abstract 2
- MINDHVHHQZYEEK-UHFFFAOYSA-N (E)-(2S,3R,4R,5S)-5-[(2S,3S,4S,5S)-2,3-epoxy-5-hydroxy-4-methylhexyl]tetrahydro-3,4-dihydroxy-(beta)-methyl-2H-pyran-2-crotonic acid ester with 9-hydroxynonanoic acid Natural products CC(O)C(C)C1OC1CC1C(O)C(O)C(CC(C)=CC(=O)OCCCCCCCCC(O)=O)OC1 MINDHVHHQZYEEK-UHFFFAOYSA-N 0.000 abstract 1
- 239000011575 calcium Substances 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- MINDHVHHQZYEEK-HBBNESRFSA-N mupirocin Chemical compound C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@@H]1[C@@H](O)[C@@H](O)[C@H](C\C(C)=C\C(=O)OCCCCCCCCC(O)=O)OC1 MINDHVHHQZYEEK-HBBNESRFSA-N 0.000 abstract 1
- 229960003128 mupirocin Drugs 0.000 abstract 1
- 229930194369 pseudomonic acid Natural products 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/195—Antibiotics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Husbandry (AREA)
- Food Science & Technology (AREA)
- Zoology (AREA)
- Birds (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Fodder In General (AREA)
- Plural Heterocyclic Compounds (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Electroluminescent Light Sources (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Materials For Photolithography (AREA)
- Gasification And Melting Of Waste (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR PSEUDOMONATO DE CALCIO CRISTALINO O UN HIDRATO DEL MISMO.COMPRENDE: A) HACER REACCIONAR UNA SOLUCION ACUOSA DE ACIDO PSEUDOMONICO CON UNA FUENTE DE IONES CALCIO, COMO OXIDO DE CALCIO, EN UN DISOLVENTE COMO AGUA Y METANOL O PROPANOL O ACETONA, PARA OBTENER PSEUDOMONATO DE CALCIO CRISTALINO; B) RECUPERAR EL PSEUDOMONATO DE CALCIO CRISTALINO POR CRISTALIZACION O PRECIPITACION EN EL DISOLVENTE ACUOSO, CON SEPARACION SELECTIVA, POR EVAPORACION DEL DISILVENTE ORGANICO; Y C) SEPARAR EL AGUA DE CRISTALIZACION POR CALENTAMIENTO A 70JC O POR ADICION DE PENTOXIDO DE FOSFORO, A 18-80JC, DURANTE 21 HORAS. SE UTILIZA EN FARMACOLOGIA PARA EL TRATAMIENTO DE INFECCIONES DE TRANSMISION SEXUAL, INFECCIONES DEL TRACTO RESPIRATORIO, MENINGITIS BACTERIANA, INFECCIONES DE LA PIEL Y TEJIDOS BLANDOS; Y EN BROMATOLOGIA COMO AGENTE PARA LA MEJORA DE LA GANANCIA DEL PESO DEL GANADO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB848415579A GB8415579D0 (en) | 1984-06-19 | 1984-06-19 | Compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES544329A0 ES544329A0 (es) | 1986-01-16 |
| ES8604249A1 true ES8604249A1 (es) | 1986-01-16 |
Family
ID=10562629
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES544329A Expired ES8604249A1 (es) | 1984-06-19 | 1985-06-18 | Un procedimiento para preparar pseudomonato de calcio cris- talino o un hidrato del mismo |
Country Status (27)
| Country | Link |
|---|---|
| US (5) | US4916155A (es) |
| EP (1) | EP0167856B1 (es) |
| JP (1) | JPH0723373B2 (es) |
| KR (1) | KR930002509B1 (es) |
| AT (1) | ATE49600T1 (es) |
| AU (1) | AU577595B2 (es) |
| CA (1) | CA1242437A (es) |
| DE (1) | DE3575428D1 (es) |
| DK (1) | DK164506C (es) |
| ES (1) | ES8604249A1 (es) |
| FI (2) | FI84179C (es) |
| GB (1) | GB8415579D0 (es) |
| GR (1) | GR851470B (es) |
| HU (1) | HU195515B (es) |
| IE (1) | IE58118B1 (es) |
| IL (1) | IL75536A (es) |
| JO (1) | JO1420B1 (es) |
| MX (1) | MX163401B (es) |
| MY (1) | MY102549A (es) |
| NO (1) | NO171593C (es) |
| NZ (1) | NZ212433A (es) |
| PH (1) | PH22951A (es) |
| PL (1) | PL254033A1 (es) |
| PT (1) | PT80657B (es) |
| YU (1) | YU45724B (es) |
| ZA (1) | ZA854549B (es) |
| ZM (1) | ZM4185A1 (es) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8415579D0 (en) * | 1984-06-19 | 1984-07-25 | Beecham Group Plc | Compounds |
| GB8530796D0 (en) * | 1985-12-13 | 1986-01-22 | Beecham Group Plc | Pharmaceutical composition |
| IE59628B1 (en) * | 1986-06-26 | 1994-03-09 | Beecham Group Plc | Treatment of fungal infections |
| US5273998A (en) * | 1990-05-11 | 1993-12-28 | Yoshitomi Pharmaceutical Industries, Ltd. | Process for making an optically active 3,4-dihydro-3,4-epoxy-2H-1-benzopyran compound |
| GB9507825D0 (en) * | 1995-04-18 | 1995-05-31 | Wet Pieter M De | Method of treatment |
| GB9616208D0 (en) | 1996-08-01 | 1996-09-11 | Smithkline Beecham Plc | Novel Compounds |
| HUP9904308A3 (en) * | 1996-10-01 | 2002-06-28 | Smithkline Beecham Plc | Use of mupirocin for manufacture of a medicament for the treatment of bacterial infections associated with colonisation by pathogenic organisms at the nasopharynx |
| CO4910145A1 (es) * | 1996-10-01 | 2000-04-24 | Smithkline Beecham Corp | Uso |
| GB9808470D0 (en) | 1998-04-22 | 1998-06-17 | Smithkline Beecham Plc | Novel process and apparatus |
| JP2003515311A (ja) * | 1999-02-03 | 2003-05-07 | ビオガル ジョジセルジャール アール テー． | 微生物学的方法によるシュードモン酸ａ抗生物質の調製方法 |
| TR200403211T3 (tr) * | 2001-06-21 | 2005-02-21 | Biogal Gyogyszergyar Rt | Psödomonik asit üretimi için metabolik olarak kontrol edilen fermantasyon işlemi. |
| IL162457A0 (en) * | 2001-12-28 | 2005-11-20 | Biogal Pharmaceutical Co | Processes for preparing crystalline and amorphous mupirocin calcium |
| IL150907A (en) * | 2002-07-25 | 2007-07-04 | Stephan Cherkez | Process for the preparation of stable amorphous calcium pseudomonate |
| WO2005009336A2 (en) * | 2003-05-01 | 2005-02-03 | Replidyne, Inc. | Antibacterial methods and compositions |
| ATE458476T1 (de) * | 2004-06-01 | 2010-03-15 | Teva Gyogyszergyar Zartkoeruen | Verfahren für die zubereitung der amorphen form eines medikamentes |
| AU2006215708B2 (en) * | 2005-02-21 | 2011-01-27 | Syngen Biotech Co., Ltd | Purification of mupirocin |
| AU2006242824B2 (en) * | 2005-05-03 | 2012-03-29 | Ranbaxy Laboratories Limited | Antimicrobial agents |
| US20070027046A1 (en) * | 2005-08-01 | 2007-02-01 | The Lubrizol Corporation | Novel Dispersants |
| GB2441328A (en) * | 2006-08-30 | 2008-03-05 | Alpharma Aps | A method for obtaining mupirocin calcium |
| US20110015413A1 (en) * | 2008-01-24 | 2011-01-20 | Nafis Defterdarovic | Process for preparing crystalline calcium mupirocin dihydrate |
| WO2010132833A1 (en) * | 2009-05-14 | 2010-11-18 | The Regents Of The University Of Michigan | Streptococcus vaccine compositions and methods of using the same |
| WO2012014109A1 (en) | 2010-07-30 | 2012-02-02 | Ranbaxy Laboratories Limited | Heterocyclic sulfonamides as inhibitors of transfer rna synthetase for use as antibacterial agents |
| WO2016133471A1 (en) | 2015-02-20 | 2016-08-25 | Pharmacti̇ve İlaç Sanayi̇ Ve Ti̇caret A. Ş. | A topical composition comprising mupirocin and dexpanthenol |
| KR102101297B1 (ko) | 2019-02-15 | 2020-05-26 | 주식회사 드림테크 | 급속 스팀 세척기 제어방법 |
| KR102269617B1 (ko) | 2020-10-27 | 2021-06-24 | 신현호 | 스팀 급속제조장치 및 그 제어방법 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1395907A (en) * | 1971-06-12 | 1975-05-29 | Beecham Group Ltd | Antibiotics |
| US4071536A (en) * | 1971-06-12 | 1978-01-31 | Beecham Group Limited | Antibiotics |
| GB1587058A (en) * | 1976-06-15 | 1981-03-25 | Beecham Group Ltd | Oxiranylmethyltetrahydropyran derivatives |
| GB1577730A (en) * | 1976-10-23 | 1980-10-29 | Beecham Group Ltd | Treatment of infections with pseudomonicacid salts or esters thereof |
| GB1577545A (en) * | 1977-07-27 | 1980-10-22 | Beecham Group Ltd | Treatment of swine dysenter |
| CA1115699A (en) * | 1978-05-20 | 1982-01-05 | Alan D. Curzons | Lithium pseudomonate and its preparation |
| GB2097670B (en) * | 1981-03-11 | 1985-02-27 | Beecham Group Ltd | Growth promotor containing pseudomonic acid |
| GB8313035D0 (en) * | 1983-05-12 | 1983-06-15 | Beecham Group Plc | Compound |
| GB8415579D0 (en) * | 1984-06-19 | 1984-07-25 | Beecham Group Plc | Compounds |
| US4892960A (en) * | 1985-01-28 | 1990-01-09 | International Minerals & Chemical Corp. | Crystalline lysocellin compositions and method of making |
-
1984
- 1984-06-19 GB GB848415579A patent/GB8415579D0/en active Pending
-
1985
- 1985-06-11 DE DE8585107163T patent/DE3575428D1/de not_active Expired - Lifetime
- 1985-06-11 EP EP85107163A patent/EP0167856B1/en not_active Expired - Lifetime
- 1985-06-11 AT AT85107163T patent/ATE49600T1/de not_active IP Right Cessation
- 1985-06-16 JO JO19851420A patent/JO1420B1/en active
- 1985-06-17 IE IE150685A patent/IE58118B1/en not_active IP Right Cessation
- 1985-06-17 AU AU43734/85A patent/AU577595B2/en not_active Expired
- 1985-06-17 PL PL25403385A patent/PL254033A1/xx unknown
- 1985-06-17 HU HU852380A patent/HU195515B/hu unknown
- 1985-06-17 ZM ZM41/85A patent/ZM4185A1/xx unknown
- 1985-06-17 GR GR851470A patent/GR851470B/el unknown
- 1985-06-17 CA CA000484212A patent/CA1242437A/en not_active Expired
- 1985-06-17 YU YU101385A patent/YU45724B/sh unknown
- 1985-06-17 ZA ZA854549A patent/ZA854549B/xx unknown
- 1985-06-17 NZ NZ212433A patent/NZ212433A/xx unknown
- 1985-06-17 NO NO852446A patent/NO171593C/no unknown
- 1985-06-17 IL IL75536A patent/IL75536A/xx not_active IP Right Cessation
- 1985-06-17 FI FI852407A patent/FI84179C/fi not_active IP Right Cessation
- 1985-06-18 MX MX6897A patent/MX163401B/es unknown
- 1985-06-18 PT PT80657A patent/PT80657B/pt unknown
- 1985-06-18 JP JP60130963A patent/JPH0723373B2/ja not_active Expired - Lifetime
- 1985-06-18 DK DK275585A patent/DK164506C/da not_active IP Right Cessation
- 1985-06-18 ES ES544329A patent/ES8604249A1/es not_active Expired
- 1985-06-18 KR KR1019850004305A patent/KR930002509B1/ko not_active Expired - Lifetime
- 1985-06-19 PH PH32428A patent/PH22951A/en unknown
-
1987
- 1987-09-21 MY MYPI87001798A patent/MY102549A/en unknown
-
1989
- 1989-04-13 US US07/338,446 patent/US4916155A/en not_active Expired - Lifetime
-
1990
- 1990-03-12 US US07/468,584 patent/US5191093A/en not_active Expired - Lifetime
-
1991
- 1991-07-04 FI FI913260A patent/FI88796C/fi not_active IP Right Cessation
-
1994
- 1994-02-28 US US08/203,681 patent/US5436266A/en not_active Expired - Lifetime
-
1995
- 1995-05-09 US US08/437,357 patent/US5569672A/en not_active Expired - Lifetime
- 1995-05-09 US US08/437,359 patent/US5792790A/en not_active Expired - Lifetime
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20051017 |