[go: up one dir, main page]

CH554876A - Procede pour preparer des arylpyrimidines. - Google Patents

Procede pour preparer des arylpyrimidines.

Info

Publication number
CH554876A
CH554876A CH1452971A CH1452971A CH554876A CH 554876 A CH554876 A CH 554876A CH 1452971 A CH1452971 A CH 1452971A CH 1452971 A CH1452971 A CH 1452971A CH 554876 A CH554876 A CH 554876A
Authority
CH
Switzerland
Prior art keywords
arylpyrimidines
preparing
preparing arylpyrimidines
Prior art date
Application number
CH1452971A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of CH554876A publication Critical patent/CH554876A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/30—Halogen atoms or nitro radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
    • C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56—One oxygen atom and one sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CH1452971A 1970-10-05 1971-10-05 Procede pour preparer des arylpyrimidines. CH554876A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7821670A 1970-10-05 1970-10-05

Publications (1)

Publication Number Publication Date
CH554876A true CH554876A (fr) 1974-10-15

Family

ID=22142671

Family Applications (4)

Application Number Title Priority Date Filing Date
CH772973A CH542218A (fr) 1970-10-05 1971-10-05 Procédé pour préparer des aryl-hydroxy-pyrimidines
CH1521472A CH554875A (fr) 1970-10-05 1971-10-05 Procede pour preparer des aryl-hydroxy-pyrimidines.
CH1532172A CH554346A (fr) 1970-10-05 1971-10-05 Procede pour preparer des arylpyrimidines.
CH1452971A CH554876A (fr) 1970-10-05 1971-10-05 Procede pour preparer des arylpyrimidines.

Family Applications Before (3)

Application Number Title Priority Date Filing Date
CH772973A CH542218A (fr) 1970-10-05 1971-10-05 Procédé pour préparer des aryl-hydroxy-pyrimidines
CH1521472A CH554875A (fr) 1970-10-05 1971-10-05 Procede pour preparer des aryl-hydroxy-pyrimidines.
CH1532172A CH554346A (fr) 1970-10-05 1971-10-05 Procede pour preparer des arylpyrimidines.

Country Status (16)

Country Link
US (1) US3707560A (fr)
JP (2) JPS5648511B1 (fr)
AT (4) AT315856B (fr)
AU (1) AU465734B2 (fr)
BE (1) BE773484A (fr)
CA (1) CA988519A (fr)
CH (4) CH542218A (fr)
DE (2) DE2149249C3 (fr)
DK (1) DK131858C (fr)
ES (4) ES395676A1 (fr)
FI (1) FI55502C (fr)
FR (1) FR2110227B1 (fr)
GB (2) GB1373535A (fr)
NL (1) NL168511C (fr)
SE (2) SE390304B (fr)
ZA (1) ZA716615B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004085433A3 (fr) * 2003-03-28 2004-12-16 Upjohn Co Modulateurs allosteriques positifs du recepteur nicotinique de l'acetylcholine

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3908012A (en) * 1970-10-05 1975-09-23 Pfizer Arylpyrimidines-inhibitors of platelet aggregation and bronchodilators
US3859288A (en) * 1970-10-05 1975-01-07 Pfizer Arylpyrimidines - inhibitors of platelet aggregation and bronchodilators
US3895112A (en) * 1970-10-05 1975-07-15 Pfizer Arylpyrimidines in the relaxation of smooth muscle
US3835132A (en) * 1972-02-01 1974-09-10 Shell Oil Co Morpholino-piperazinyl pyrimidines
US3950525A (en) * 1973-06-19 1976-04-13 Pfizer Inc. Relaxation of smooth muscle in a mammal
DE2343419A1 (de) * 1973-08-29 1975-03-13 Gruenenthal Chemie Verfahren zur herstellung von pyrimidinderivaten
US4725600A (en) * 1984-07-13 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Pyrimidine compounds having activity as a cardiotonic anti-hypertensive cerebrovascular vasodilator and anti-platelet aggregation agent
US4935516A (en) * 1988-01-29 1990-06-19 Ube Industries, Ltd. Process for preparing 4-hydroxypyrimidine
JPH0625157B2 (ja) * 1988-01-29 1994-04-06 宇部興産株式会社 ４―ヒドロキシピリミジン類の製造方法
DE3825647A1 (de) * 1988-07-28 1990-02-01 Geyer Gmbh & Co Christian Vorrichtung zur befestigung eines elektrischen schaltgeraetes
DE3905364A1 (de) * 1989-02-22 1990-08-23 Hoechst Ag Substituierte pyrimidin-derivate, verfahren zu ihrer herstellung und ihre verwendung als tool
WO2001005783A1 (fr) * 1999-07-15 2001-01-25 Pharmacopeia, Inc. Antagonistes du recepteur b1 de la bradykinine
ATE366045T1 (de) * 2002-03-15 2007-07-15 Ciba Sc Holding Ag Verwendung von 4-aminopyrimidinen zur antimikrobiellen behandlung von oberflächen
MXPA04011472A (es) * 2002-05-22 2005-02-14 Amgen Inc Derivados de amino-piridina, piridina y piridazina para usarse como ligandos del receptor vaniloide para el tratamiento del dolor.
EP1877400A1 (fr) * 2005-04-15 2008-01-16 Amgen, Inc Ligands recepteurs de vanilloide et leur utilisation dans les traitements
JP2009164373A (ja) * 2008-01-08 2009-07-23 Toshiba Corp 半導体装置
WO2011091153A1 (fr) * 2010-01-25 2011-07-28 Chdi, Inc. Certains inhibiteurs de kynurénine-3-monooxygénase, compositions pharmaceutiques, et procédés d'utilisation de ceux-ci
BR112014004845A2 (pt) 2011-08-30 2017-04-04 Chdi Foundation Inc pelo menos uma entidade química; pelo menos um composto; composição farmacêutica; uso de uma quantidade terapeuticamente eficaz de pelo menos uma entidade química; composição farmacêutica embalada
EP3243515B1 (fr) 2011-08-30 2019-10-16 CHDI Foundation, Inc. Inhibiteurs de kynurenine-3-monooxygenase, compositions pharmaceutiques et leurs procédés d'utilisation
EA034528B1 (ru) 2014-07-17 2020-02-17 Сиэйчдиай Фаундэйшн, Инк. Способ лечения нарушений, связанных с вич

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3047462A (en) * 1959-03-06 1962-07-31 Lab Jacques Logeais Soc D Expl Quinazolone anti-inflammatory composition

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004085433A3 (fr) * 2003-03-28 2004-12-16 Upjohn Co Modulateurs allosteriques positifs du recepteur nicotinique de l'acetylcholine

Also Published As

Publication number Publication date
NL168511C (nl) 1982-04-16
FR2110227B1 (fr) 1975-02-07
DE2149249B2 (de) 1974-11-07
DE2149249A1 (de) 1972-04-13
ES420209A1 (es) 1976-06-01
JPS5636468A (en) 1981-04-09
AT314540B (de) 1974-04-10
AT316563B (de) 1974-06-15
FR2110227A1 (fr) 1972-06-02
ES395676A1 (es) 1974-10-16
CH554875A (fr) 1974-10-15
CH542218A (fr) 1973-11-15
NL168511B (nl) 1981-11-16
DK131858C (da) 1976-02-16
DE2165962C2 (de) 1982-05-13
FI55502C (fi) 1979-08-10
AU465734B2 (en) 1975-10-09
SE385885B (sv) 1976-07-26
US3707560A (en) 1972-12-26
SE7410488L (fr) 1974-08-16
NL7113670A (fr) 1972-04-07
BE773484A (fr) 1972-04-05
CH554346A (fr) 1974-09-30
JPS578107B2 (fr) 1982-02-15
FI55502B (fi) 1979-04-30
GB1373536A (en) 1974-11-13
DE2149249C3 (de) 1975-07-03
AT315856B (de) 1974-05-15
DK131858B (da) 1975-09-15
ZA716615B (en) 1972-06-28
JPS5648511B1 (fr) 1981-11-16
AT317229B (de) 1974-08-26
CA988519A (en) 1976-05-04
ES420210A1 (es) 1976-06-01
AU3425971A (en) 1973-04-12
GB1373535A (en) 1974-11-13
SE390304B (sv) 1976-12-13
DE2165962A1 (de) 1972-08-31
ES420211A1 (es) 1976-03-16

Similar Documents

Publication Publication Date Title
BE775375A (fr) Procede pour preparer une composition vitrifiable
BE746534R (fr) Procede pour preparer du
CH554875A (fr) Procede pour preparer des aryl-hydroxy-pyrimidines.
BE762382A (fr) Procede pour decafeiner le cafe
FR2099535A1 (fr) Procede pour le nettoyage des textiles
BE774828A (fr) Procede pour ameliorer des pieces coulees
BE765185A (fr) Procede de fonderie
RO62510A (fr) Procede pour obtenir des 1,2,4-triazin-5-ones
BE792936A (fr) Procede pour produire des supraconducteurs
BE784559A (fr) Procede pour preparer des lactames
RO70060A (fr) Procede pour preparer un compose de 4-(4-biphenylile)-1-butanole
RO84248A (fr) Procede pour preparer 2(-aminophenylimino)-3-aza-cycloalcanes
RO63842A (fr) Procede pour preparer des 7-acyleamido-7-methoxy-cephal
BE789550A (fr) Procede pour preparer des dispersions photosensibles
CH546754A (fr) Procede pour la preparation des furanones.
CH553785A (fr) Procede de preparation de nouvelles dibenzoazepines.
RO62267A (fr) Procede pour la preparation des 1-phenoxy-2-hydroxy-3-hydroxyalkylaminopropanes
BE797983A (fr) Procede ameliore pour preparer des 2- quinoxalinecar boxamide-1,4-dioxydes
BE790093A (fr) Procede pour preparer des agents antibacteriens
CH551937A (fr) Procede de preparation de saligenol.
BE775308A (fr) Procede pour preparer des produits electrophotographiques ameliores
RO62296A (fr) Procede pour la preparation des phenylaminoalcanes
RO61927A2 (fr) Procede pour la preparation des tribromepyrazolylacetamides
RO62279A (fr) Procede de preparation des revelateurs de contraste pour roentgenographies
FR2282865A2 (fr) Procede pour preparer de nouvelles substances antibiotiques

Legal Events

Date Code Title Description
PL Patent ceased