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BRPI0908353B8 - composto ou um sal farmaceuticamente aceitavel do mesmo e composição farmaceutica - Google Patents

composto ou um sal farmaceuticamente aceitavel do mesmo e composição farmaceutica

Info

Publication number
BRPI0908353B8
BRPI0908353B8 BRPI0908353A BRPI0908353A BRPI0908353B8 BR PI0908353 B8 BRPI0908353 B8 BR PI0908353B8 BR PI0908353 A BRPI0908353 A BR PI0908353A BR PI0908353 A BRPI0908353 A BR PI0908353A BR PI0908353 B8 BRPI0908353 B8 BR PI0908353B8
Authority
BR
Brazil
Prior art keywords
pharmaceutically acceptable
pharmaceutical composition
compound
acceptable salt
compounds
Prior art date
Application number
BRPI0908353A
Other languages
English (en)
Inventor
Bailey Andrew
James Robbins Andrew
Stuart Lister Andrew
John Teobald Barry
Alcaraz Lilian
John Stocks Michael
David Kindon Nicholas
James Bull Richard
Johnson Timothy
Original Assignee
Astrazeneca Ab
Pulmagen Therapeutics Synergy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0802192A external-priority patent/GB0802192D0/en
Priority claimed from GB0822437A external-priority patent/GB0822437D0/en
Application filed by Astrazeneca Ab, Pulmagen Therapeutics Synergy filed Critical Astrazeneca Ab
Publication of BRPI0908353A2 publication Critical patent/BRPI0908353A2/pt
Publication of BRPI0908353B1 publication Critical patent/BRPI0908353B1/pt
Publication of BRPI0908353B8 publication Critical patent/BRPI0908353B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
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    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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    • A—HUMAN NECESSITIES
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  • Health & Medical Sciences (AREA)
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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
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Abstract

compostos, processo para a sua preparação e uso destes compostos, composição farmacêutica e processo para sua fabricação, produto farmacêutico. a presente invenção refere-se a derivados de amida espirocíclica da fórmula l, (l) sais farmaceuticamente aceitáveis dos mesmos, um processo para sua preparação, composições farmacêuticas contendo-os, e seu uso em terapia.
BRPI0908353A 2008-02-06 2009-02-04 composto ou um sal farmaceuticamente aceitavel do mesmo e composição farmaceutica BRPI0908353B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0802192A GB0802192D0 (en) 2008-02-06 2008-02-06 Compounds
GB0822437A GB0822437D0 (en) 2008-12-09 2008-12-09 Compounds
PCT/GB2009/000298 WO2009098448A1 (en) 2008-02-06 2009-02-04 Compounds

Publications (3)

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DK2242759T3 (da) 2012-12-17
BRPI0908353B1 (pt) 2019-11-05
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AU2009211251A1 (en) 2009-08-13
BRPI0908353A2 (pt) 2015-07-28
UY31639A1 (es) 2009-09-30
AR070571A1 (es) 2010-04-21
CU20100159A7 (es) 2011-10-31
IL207038A0 (en) 2010-12-30
EA018711B1 (ru) 2013-10-30
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PE20091572A1 (es) 2009-11-04
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MX2010008577A (es) 2010-11-25
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NI201000138A (es) 2012-09-10
IL207038A (en) 2015-10-29
CN102083839A (zh) 2011-06-01
US20120322788A1 (en) 2012-12-20
US20090298807A1 (en) 2009-12-03
WO2009098448A1 (en) 2009-08-13
SI2242759T1 (sl) 2013-01-31
CL2009000271A1 (es) 2010-06-18
DOP2010000246A (es) 2010-11-15
JP4934223B2 (ja) 2012-05-16
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US8629271B2 (en) 2014-01-14
CY1113734T1 (el) 2016-06-22
HK1149258A1 (en) 2011-09-30
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PT2242759E (pt) 2012-12-17
CR11623A (es) 2011-02-04
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MY149731A (en) 2013-10-14
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